Protein: NHR49
Nuclear hormone receptor family member nhr-49

Gene: NHR49, nhr-49
Organism: Caenorhabditis elegans
Interactions: 70
UniProt ID: O45666

Gene Ontology (top 5):
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0004879 - nuclear receptor activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

234151

NHR19
Nuclear hormone receptor family member nhr-19

4

20

Small-scale

0.904

High

234167

NHR76
Nuclear hormone receptor family member nhr-76

4

20

Small-scale

0.904

High

234177

NHR13
Nuclear hormone receptor family member nhr-13

4

20

Small-scale

0.904

High

234178

Q9NAJ3
Nuclear receptor domain-containing protein

4

20

Small-scale

0.904

High

234174

NHR71
Nuclear hormone receptor family member nhr-71

4

20

Small-scale

0.889

High

115197

NHR66
Nuclear hormone receptor family member nhr-66

3

20

Small-scale

0.869

High

234144

NHR49
Nuclear hormone receptor family member nhr-49

3

20

Small-scale

0.869

High

114037

G5EGP2
Nuclear receptor domain-containing protein

3

19

Small-scale

0.852

High

196754

NHR79
Nuclear hormone receptor family member nhr-79

3

20

Small-scale

0.852

High

233373

O44577
NR LBD domain-containing protein

3

19

Small-scale

0.852

High

234153

NHR22
Nuclear hormone receptor family member nhr-22

3

20

Small-scale

0.852

High

234166

Q3LQX0
Nuclear Hormone Receptor family

3

20

Small-scale

0.825

High

195399

O16346
Nuclear Hormone Receptor family

2

19

High-throughput

0.815

High

234152

NHR20
Nuclear hormone receptor family member nhr-20

2

20

High-throughput

0.815

High

234145

O45987
Nuclear Hormone Receptor family

2

20

Small-scale

0.791

High

234183

Q9U1R0
Nuclear Hormone Receptor family

2

20

Small-scale

0.791

High

234165

NHR11
Nuclear hormone receptor family member nhr-11

2

20

Small-scale

0.768

High

234169

Q86PJ4
Nuclear Hormone Receptor family

2

20

High-throughput

0.730

High

234161

MED15
Mediator of RNA polymerase II transcription subunit 15

4

8

Small-scale

0.681

High

195589

O16537
Nuclear receptor domain-containing protein

1

19

High-throughput

0.656

High

195590

O16538
Nuclear receptor

1

19

High-throughput

0.656

High

195887

O17013
Nuclear Hormone Receptor family

1

19

High-throughput

0.656

High

195888

O17020
Nuclear Hormone Receptor family

1

19

High-throughput

0.656

High

195938

O17081
Nuclear Hormone Receptor family

1

19

High-throughput

0.656

High

196432

NH169
Nuclear hormone receptor family member nhr-169

1

19

High-throughput

0.656

High

233913

O45507
Nuclear Hormone Receptor family

1

19

High-throughput

0.656

High

234149

P90822
Nuclear Hormone Receptor family

1

20

High-throughput

0.656

High

234159

Q20097
Nuclear Hormone Receptor family

1

20

High-throughput

0.656

High

234172

Q95Y05
NR LBD domain-containing protein

1

20

High-throughput

0.656

High

234173

Q9BKZ8
Nuclear receptor domain-containing protein

1

20

High-throughput

0.656

High

234182

NH121
Nuclear hormone receptor family member nhr-121

1

20

High-throughput

0.656

High

234185

NHR85
Nuclear hormone receptor family member nhr-85

1

20

High-throughput

0.656

High

234186

NHR67
Nuclear hormone receptor family member nhr-67

1

20

High-throughput

0.656

High

234168

Q86PI8
Nuclear receptor NHR-114

1

20

High-throughput

0.621

High

234180

HMBX1
Homeobox-containing protein 1

2

14

Small-scale

0.613

High

112616

NH114
Nuclear hormone receptor 114

1

20

High-throughput

0.590

High

234158

Q19438
Nuclear Hormone Receptor family

1

20

High-throughput

0.590

High

234170

NHR80
Nuclear hormone receptor family member nhr-80

1

20

Small-scale

0.575

High

234187

Q9XXK5
Suppressor of Constitutive Dauer formation

2

11

Small-scale

0.559

High

111457

PAX3H
Paired box protein 3 homolog

1

14

High-throughput

0.508

High

111578

DCP66
Transcription factor dcp-66

1

4

High-throughput

0.508

High

112058

OVOLH
Transcription factor ovo-like homolog lin-48

1

10

High-throughput

0.508

High

196280

EYA1
Protein phosphatase eya-1

1

6

High-throughput

0.508

High

196818

MAB3
Protein male abnormal 3

1

5

High-throughput

0.508

High

233876

O45494
C2H2-type domain-containing protein

1

9

High-throughput

0.508

High

234148

HM09
Homeobox protein ceh-9

1

17

High-throughput

0.508

High

234150

RAPSN
43 kDa receptor-associated protein of the synapse homolog

1

8

High-throughput

0.508

High

234154

PHA4
Defective pharyngeal development protein 4

1

20

High-throughput

0.508

High

234156

HMX
Homeobox protein mls-2

1

20

High-throughput

0.508

High

234157

ZTF2
Zinc finger protein ztf-2

1

8

High-throughput

0.508

High

234162

EGL43
Zinc finger protein egl-43

1

9

High-throughput

0.508

High

234164

KMT5A
Histone-lysine N-methyltransferase set-1

1

20

High-throughput

0.508

High

234175

Q9N360
C2H2-type domain-containing protein

1

9

High-throughput

0.508

High

92566

D3YT85
DM domain-containing protein

1

9

High-throughput

0.481

High

234147

PLK1
Serine/threonine-protein kinase plk-1

1

4

High-throughput

0.479

High

234171

MBK1
Dual specificity tyrosine-phosphorylation-regulated kinase mbk-1

1

11

High-throughput

0.479

High

234155

Q18477
Histone deacetylase 11

1

16

High-throughput

0.464

High

234160

Q21177
Uncharacterized protein

1

9

High-throughput

0.464

High

234176

Q9N410
BHLH domain-containing protein

1

6

High-throughput

0.464

High

234179

Q9TXM1
Uncharacterized protein

1

0

High-throughput

0.458

High

115704

ZTF16
Zinc finger protein ztf-16

1

13

High-throughput

0.457

High

233685

O45075
PHD-type domain-containing protein

1

15

High-throughput

0.457

High

234146

O62159
DM domain-containing protein

1

9

High-throughput

0.457

High

234184

TAF12
Transcription initiation factor TFIID subunit 12

1

3

High-throughput

0.457

High

232263

O44490
ELKS/RAB6-interacting/CAST family member 2

1

8

High-throughput

0.437

High

234163

Q22032
Transthyretin-like family protein

2

0

Small-scale

0.319

High

234181

Q9TZ84
Ubiquitin-like domain-containing protein

2

0

Small-scale

0.319

High

72175

PLIN1
Perilipin-1 homolog

1

0

Small-scale

0.251

Low

96215

E9P875
Neurexin-3-beta

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025