Protein: CATL1
Procathepsin L (EC 3.4.22.15) (Cathepsin L1) (Major excreted protein) (MEP) [Cleaved into: Cathepsin L; Cathepsin L heavy chain; Cathepsin L light chain]

Gene: CATL1, CTSL
Organism: Homo sapiens
Interactions: 223
UniProt ID: P07711

Gene Ontology (top 5):
GO:0001968 - fibronectin binding
GO:0002250 - adaptive immune response
GO:0004197 - cysteine-type endopeptidase activity
GO:0005518 - collagen binding
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

429802

CATH
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H

3

6

High-throughput

0.861

High

345044

CYTA
Cystatin-A

3

6

Small-scale

0.857

High

245778

CATL2
Cathepsin L2

3

6

High-throughput

0.855

High

283668

CYTF
Cystatin-F

2

13

High-throughput

0.811

High

344922

CYTN
Cystatin-SN

2

13

High-throughput

0.811

High

429843

CATK
Cathepsin K

2

6

High-throughput

0.811

High

130182

BT3A3
Butyrophilin subfamily 3 member A3

1

2

High-throughput

0.698

High

344815

CYTC
Cystatin-C

1

13

High-throughput

0.691

High

345171

KNG1
Kininogen-1

1

13

High-throughput

0.691

High

376059

CYTB
Cystatin-B

1

6

High-throughput

0.691

High

429900

CYTM
Cystatin-M

1

13

High-throughput

0.691

High

429901

GRDN
Girdin

3

3

High-throughput

0.667

High

429797

CATL1
Procathepsin L

1

6

High-throughput

0.665

High

429856

CLH2
Clathrin heavy chain 2

3

0

High-throughput

0.638

High

429904

CATL3
Putative inactive cathepsin L-like protein CTSL3P

2

7

High-throughput

0.637

High

429811

MPRI
Cation-independent mannose-6-phosphate receptor

2

4

High-throughput

0.621

High

429829

SPB3
Serpin B3

2

2

Small-scale

0.619

High

429907

CREL2
Protein disulfide isomerase CRELD2

2

2

High-throughput

0.576

High

213450

SGTA
Small glutamine-rich tetratricopeptide repeat-containing protein alpha

1

5

High-throughput

0.573

High

429873

RELB
Transcription factor RelB

1

3

High-throughput

0.541

High

409492

HEPS
Serine protease hepsin

1

3

High-throughput

0.536

High

429937

TMPSD
Transmembrane protease serine 13

1

3

High-throughput

0.536

High

429922

RSPH1
Radial spoke head 1 homolog

1

0

High-throughput

0.518

High

117559

MYO1C
Unconventional myosin-Ic

1

5

High-throughput

0.515

High

164553

SPTN2
Spectrin beta chain, non-erythrocytic 2

1

6

High-throughput

0.515

High

216145

CALU
Calumenin

1

3

High-throughput

0.515

High

254032

WDR1
WD repeat-containing protein 1

1

1

High-throughput

0.515

High

280181

CBPD
Carboxypeptidase D

1

1

High-throughput

0.515

High

297271

MYO1D
Unconventional myosin-Id

1

5

High-throughput

0.515

High

382264

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

2

High-throughput

0.515

High

385933

P53
Cellular tumor antigen p53

1

1

High-throughput

0.515

High

393943

A4
Amyloid-beta precursor protein

1

1

High-throughput

0.515

High

429798

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

2

High-throughput

0.515

High

429806

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

2

High-throughput

0.515

High

429815

PDIA4
Protein disulfide-isomerase A4

1

8

High-throughput

0.515

High

429816

P4HA1
Prolyl 4-hydroxylase subunit alpha-1

1

1

High-throughput

0.515

High

429818

SYDC
Aspartate--tRNA ligase, cytoplasmic

1

2

High-throughput

0.515

High

429821

PFKAL
ATP-dependent 6-phosphofructokinase, liver type

1

3

High-throughput

0.515

High

429827

CALR
Calreticulin

1

5

High-throughput

0.515

High

429840

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

1

High-throughput

0.515

High

429874

PFKAP
ATP-dependent 6-phosphofructokinase, platelet type

1

3

High-throughput

0.515

High

429882

AIMP1
Aminoacyl tRNA synthase complex-interacting multifunctional protein 1

1

2

High-throughput

0.515

High

429888

DX39B
Spliceosome RNA helicase DDX39B

1

1

High-throughput

0.515

High

429894

SYK
Lysine--tRNA ligase

1

2

High-throughput

0.515

High

429898

SAFB1
Scaffold attachment factor B1

1

2

High-throughput

0.515

High

429902

DHB12
Very-long-chain 3-oxoacyl-CoA reductase

1

1

High-throughput

0.515

High

429921

IPO4
Importin-4

1

1

High-throughput

0.515

High

429947

DJB11
DnaJ homolog subfamily B member 11

1

4

High-throughput

0.515

High

429958

HYOU1
Hypoxia up-regulated protein 1

1

1

High-throughput

0.515

High

361299

APOA1
Apolipoprotein A-I

1

0

High-throughput

0.513

High

363692

ALBU
Albumin

1

0

High-throughput

0.513

High

429859

GEM
GTP-binding protein GEM

1

1

High-throughput

0.508

High

429822

RXRA
Retinoic acid receptor RXR-alpha

1

1

Small-scale

0.501

High

429931

RARR2
Retinoic acid receptor responder protein 2

1

1

Small-scale

0.501

High

123463

PGRC1
Membrane-associated progesterone receptor component 1

1

0

High-throughput

0.493

High

364139

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.493

High

429837

LONM
Lon protease homolog, mitochondrial

1

0

High-throughput

0.493

High

429842

SYIC
Isoleucine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.493

High

267850

EED
Polycomb protein EED

1

0

High-throughput

0.486

High

429838

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

0

Small-scale

0.486

High

169016

ARPC3
Actin-related protein 2/3 complex subunit 3

1

1

High-throughput

0.479

High

199861

SPIT2
Kunitz-type protease inhibitor 2

1

1

High-throughput

0.479

High

201556

MCA3
Eukaryotic translation elongation factor 1 epsilon-1

1

1

High-throughput

0.479

High

211465

ACTN4
Alpha-actinin-4

1

4

High-throughput

0.479

High

214470

MYO1B
Unconventional myosin-Ib

1

5

High-throughput

0.479

High

237013

PLOD3
Multifunctional procollagen lysine hydroxylase and glycosyltransferase LH3 [Includes: Procollagen-lysine,2-oxoglutarate 5-dioxygenase 3

1

3

High-throughput

0.479

High

243259

DNJA2
DnaJ homolog subfamily A member 2

1

5

High-throughput

0.479

High

299821

ERLN2
Erlin-2

1

1

High-throughput

0.479

High

403734

ITB1
Integrin beta-1

1

1

High-throughput

0.479

High

411944

FYN
Tyrosine-protein kinase Fyn

1

1

High-throughput

0.479

High

429799

LAMB1
Laminin subunit beta-1

1

1

High-throughput

0.479

High

429800

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

1

High-throughput

0.479

High

429807

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.479

High

429809

LAMC1
Laminin subunit gamma-1

1

1

High-throughput

0.479

High

429812

ACTN1
Alpha-actinin-1

1

4

High-throughput

0.479

High

429813

XRCC6
X-ray repair cross-complementing protein 6

1

1

High-throughput

0.479

High

429814

XRCC5
X-ray repair cross-complementing protein 5

1

1

High-throughput

0.479

High

429817

ENPL
Endoplasmin

1

2

High-throughput

0.479

High

429823

MSH3
DNA mismatch repair protein Msh3

1

1

High-throughput

0.479

High

429824

VDAC1
Voltage-dependent anion-selective channel protein 1

1

2

High-throughput

0.479

High

429831

PDIA3
Protein disulfide-isomerase A3

1

9

High-throughput

0.479

High

429833

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

429835

BASI
Basigin

1

1

High-throughput

0.479

High

429839

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

1

High-throughput

0.479

High

429844

MSH2
DNA mismatch repair protein Msh2

1

1

High-throughput

0.479

High

429845

NAMPT
Nicotinamide phosphoribosyltransferase

1

1

High-throughput

0.479

High

429846

VDAC2
Voltage-dependent anion-selective channel protein 2

1

2

High-throughput

0.479

High

429851

LMAN1
Protein ERGIC-53

1

1

High-throughput

0.479

High

429852

EFTU
Elongation factor Tu, mitochondrial

1

1

High-throughput

0.479

High

429854

SERPH
Serpin H1

1

4

High-throughput

0.479

High

429858

SYYC
Tyrosine--tRNA ligase, cytoplasmic

1

2

High-throughput

0.479

High

429861

SYMC
Methionine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

429862

RBM11
Splicing regulator RBM11

1

2

High-throughput

0.479

High

429863

RAB10
Ras-related protein Rab-10

1

1

High-throughput

0.479

High

429868

GNAS2
Guanine nucleotide-binding protein G(s) subunit alpha isoforms short

1

1

High-throughput

0.479

High

429869

TPM4
Tropomyosin alpha-4 chain

1

3

High-throughput

0.479

High

429871

PRKDC
DNA-dependent protein kinase catalytic subunit

1

1

High-throughput

0.479

High

429875

KIF23
Kinesin-like protein KIF23

1

1

High-throughput

0.479

High

429876

M2OM
Mitochondrial 2-oxoglutarate/malate carrier protein

1

4

High-throughput

0.479

High

429879

CKAP4
Cytoskeleton-associated protein 4

1

4

High-throughput

0.479

High

429880

SSRP1
FACT complex subunit SSRP1

1

2

High-throughput

0.479

High

429881

TP53B
TP53-binding protein 1

1

1

High-throughput

0.479

High

429883

PRDX4
Peroxiredoxin-4

1

1

High-throughput

0.479

High

429887

SPTN1
Spectrin alpha chain, non-erythrocytic 1

1

6

High-throughput

0.479

High

429889

SAFB2
Scaffold attachment factor B2

1

2

High-throughput

0.479

High

429892

MDC1
Mediator of DNA damage checkpoint protein 1

1

1

High-throughput

0.479

High

429893

GANAB
Neutral alpha-glucosidase AB

1

1

High-throughput

0.479

High

429896

PON2
Serum paraoxonase/arylesterase 2

1

2

High-throughput

0.479

High

429899

MLF2
Myeloid leukemia factor 2

1

1

High-throughput

0.479

High

429903

TGO1
Transport and Golgi organization protein 1 homolog

1

1

High-throughput

0.479

High

429905

UBR4
E3 ubiquitin-protein ligase UBR4

1

1

High-throughput

0.479

High

429912

PLD3
5'-3' exonuclease PLD3

1

1

High-throughput

0.479

High

429913

GCC2
GRIP and coiled-coil domain-containing protein 2

1

3

High-throughput

0.479

High

429914

PELP1
Proline-, glutamic acid- and leucine-rich protein 1

1

1

High-throughput

0.479

High

429923

MYDGF
Myeloid-derived growth factor

1

1

High-throughput

0.479

High

429926

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

3

High-throughput

0.479

High

429930

RNF5
E3 ubiquitin-protein ligase RNF5

1

2

High-throughput

0.479

High

429939

TMX1
Thioredoxin-related transmembrane protein 1

1

10

High-throughput

0.479

High

429940

GBB4
Guanine nucleotide-binding protein subunit beta-4

1

1

High-throughput

0.479

High

429941

XPO5
Exportin-5

1

2

High-throughput

0.479

High

429942

RAB18
Ras-related protein Rab-18

1

1

High-throughput

0.479

High

429949

ATS1
A disintegrin and metalloproteinase with thrombospondin motifs 1

1

1

High-throughput

0.479

High

429950

S2513
Electrogenic aspartate/glutamate antiporter SLC25A13, mitochondrial

1

2

High-throughput

0.479

High

429951

ACINU
Apoptotic chromatin condensation inducer in the nucleus

1

1

High-throughput

0.479

High

429953

MYO6
Unconventional myosin-VI

1

1

High-throughput

0.479

High

429954

CHIP
E3 ubiquitin-protein ligase CHIP

1

4

High-throughput

0.479

High

429955

VDAC3
Voltage-dependent anion-selective channel protein 3

1

2

High-throughput

0.479

High

429959

YTHD2
YTH domain-containing family protein 2

1

3

High-throughput

0.479

High

161001

CLGN
Calmegin

1

5

High-throughput

0.470

High

323548

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.470

High

390020

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

2

High-throughput

0.470

High

390661

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

1

High-throughput

0.470

High

429849

SYQ
Glutamine--tRNA ligase

1

2

High-throughput

0.470

High

429897

RCN1
Reticulocalbin-1

1

3

High-throughput

0.470

High

429848

BAG6
Large proline-rich protein BAG6

1

0

High-throughput

0.460

High

153267

CDIPT
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

1

0

High-throughput

0.458

High

168873

ARPC2
Actin-related protein 2/3 complex subunit 2

1

0

High-throughput

0.458

High

197190

SERA
D-3-phosphoglycerate dehydrogenase

1

0

High-throughput

0.458

High

204940

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.458

High

215094

LANC1
Glutathione S-transferase LANCL1

1

0

High-throughput

0.458

High

257738

SIN3B
Paired amphipathic helix protein Sin3b

1

0

High-throughput

0.458

High

268371

BAF
Barrier-to-autointegration factor

1

0

High-throughput

0.458

High

376409

APOB
Apolipoprotein B-100

1

0

High-throughput

0.458

High

417668

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.458

High

429291

SAP
Prosaposin

1

0

High-throughput

0.458

High

429801

SNRPA
U1 small nuclear ribonucleoprotein A

1

0

High-throughput

0.458

High

429803

PARP1
Poly [ADP-ribose] polymerase 1

1

0

High-throughput

0.458

High

429804

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

0

High-throughput

0.458

High

429805

CO4A
Complement C4-A

1

0

Small-scale

0.458

High

429808

CLUS
Clusterin

1

0

High-throughput

0.458

High

429810

ODPB
Pyruvate dehydrogenase E1 component subunit beta, mitochondrial

1

0

High-throughput

0.458

High

429819

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

429820

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

429826

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.458

High

429828

GRN
Progranulin

1

0

High-throughput

0.458

High

429832

PUR9
Bifunctional purine biosynthesis protein ATIC

1

0

High-throughput

0.458

High

429847

CBX5
Chromobox protein homolog 5

1

0

High-throughput

0.458

High

429850

ATPO
ATP synthase subunit O, mitochondrial

1

0

High-throughput

0.458

High

429855

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

429857

SYRC
Arginine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

429864

ARP3
Actin-related protein 3

1

0

High-throughput

0.458

High

429865

RHOA
Transforming protein RhoA

1

0

High-throughput

0.458

High

429866

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.458

High

429870

GTF2I
General transcription factor II-I

1

0

High-throughput

0.458

High

429872

TFAM
Transcription factor A, mitochondrial

1

0

High-throughput

0.458

High

429877

LGUL
Lactoylglutathione lyase

1

0

High-throughput

0.458

High

429878

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

429890

WRN
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN

1

0

High-throughput

0.458

High

429891

DSC3
Desmocollin-3

1

0

High-throughput

0.458

High

429910

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

429919

NUP35
Nucleoporin NUP35

1

0

High-throughput

0.458

High

429925

FAF2
FAS-associated factor 2

1

0

High-throughput

0.458

High

429928

CLCC1
Chloride channel CLIC-like protein 1

1

0

High-throughput

0.458

High

429929

RBM15
RNA-binding protein 15

1

0

High-throughput

0.458

High

429932

GRWD1
Glutamate-rich WD repeat-containing protein 1

1

0

High-throughput

0.458

High

429936

PDIP3
Polymerase delta-interacting protein 3

1

0

High-throughput

0.458

High

429944

T106B
Transmembrane protein 106B

1

0

High-throughput

0.458

High

429945

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

0

High-throughput

0.458

High

429948

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

429952

AKP8L
A-kinase anchor protein 8-like

1

0

High-throughput

0.458

High

429956

ITM2B
Integral membrane protein 2B

1

0

High-throughput

0.458

High

429960

SP16H
FACT complex subunit SPT16

1

0

High-throughput

0.458

High

429962

CLIC4
Chloride intracellular channel protein 4

1

0

High-throughput

0.458

High

429908

H32
Histone H3.2

1

1

Small-scale

0.445

High

164754

SC16A
Protein transport protein Sec16A

1

1

High-throughput

0.437

High

327155

TXD12
Thioredoxin domain-containing protein 12

1

1

High-throughput

0.437

High

355123

HBD
Hemoglobin subunit delta

1

1

High-throughput

0.437

High

429825

FKBP2
Peptidyl-prolyl cis-trans isomerase FKBP2

1

1

High-throughput

0.437

High

429830

ERP29
Endoplasmic reticulum resident protein 29

1

9

High-throughput

0.437

High

429895

NOMO1
BOS complex subunit NOMO1

1

1

High-throughput

0.437

High

429906

MIC13
MICOS complex subunit MIC13

1

1

High-throughput

0.437

High

429911

YTHD3
YTH domain-containing family protein 3

1

3

High-throughput

0.437

High

429916

EMC1
ER membrane protein complex subunit 1

1

1

High-throughput

0.437

High

429917

TTC13
Tetratricopeptide repeat protein 13

1

4

High-throughput

0.437

High

429934

EFHD1
EF-hand domain-containing protein D1

1

3

High-throughput

0.437

High

429938

YTHD1
YTH domain-containing family protein 1

1

3

High-throughput

0.437

High

429943

TOM22
Mitochondrial import receptor subunit TOM22 homolog

1

1

High-throughput

0.437

High

354029

IGHA1
Immunoglobulin heavy constant alpha 1

1

0

High-throughput

0.426

High

364509

TRFE
Serotransferrin

1

0

High-throughput

0.426

High

429918

MCPH1
Microcephalin

1

0

Small-scale

0.251

Low

130405

NDUA4
Cytochrome c oxidase subunit NDUFA4

1

0

High-throughput

0.249

Low

215420

SCO2
Protein SCO2 homolog, mitochondrial

1

0

High-throughput

0.249

Low

256444

ZC11A
Zinc finger CCCH domain-containing protein 11A

1

0

High-throughput

0.249

Low

429834

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

429836

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

High-throughput

0.249

Low

429841

ECHA
Trifunctional enzyme subunit alpha, mitochondrial

1

0

High-throughput

0.249

Low

429853

SRP09
Signal recognition particle 9 kDa protein

1

0

High-throughput

0.249

Low

429860

ECHB
Trifunctional enzyme subunit beta, mitochondrial

1

0

High-throughput

0.249

Low

429867

CNBP
CCHC-type zinc finger nucleic acid binding protein

1

0

High-throughput

0.249

Low

429884

NDK3
Nucleoside diphosphate kinase 3

1

0

High-throughput

0.249

Low

429885

SRSF9
Serine/arginine-rich splicing factor 9

1

0

High-throughput

0.249

Low

429886

CUL2
Cullin-2

1

0

High-throughput

0.249

Low

429909

RIR2B
Ribonucleoside-diphosphate reductase subunit M2 B

1

0

High-throughput

0.249

Low

429915

ATPF2
ATP synthase mitochondrial F1 complex assembly factor 2

1

0

High-throughput

0.249

Low

429920

THOC2
THO complex subunit 2

1

0

High-throughput

0.249

Low

429924

NCLN
BOS complex subunit NCLN

1

0

High-throughput

0.249

Low

429927

FMC1
Protein FMC1 homolog

1

0

High-throughput

0.249

Low

429933

NTPCR
Cancer-related nucleoside-triphosphatase

1

0

High-throughput

0.249

Low

429935

WDR18
WD repeat-containing protein 18

1

0

High-throughput

0.249

Low

429946

DHCR7
7-dehydrocholesterol reductase

1

0

High-throughput

0.249

Low

429957

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.249

Low

429961

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024