Protein: 5HT6R
5-hydroxytryptamine receptor 6 (5-HT-6) (5-HT6) (Serotonin receptor 6)

Gene: 5HT6R, HTR6
Organism: Homo sapiens
Interactions: 54
UniProt ID: P50406

Gene Ontology (top 5):
GO:0004969 - histamine receptor activity
GO:0004993 - G protein-coupled serotonin receptor activity
GO:0005886 - plasma membrane
GO:0005929 - cilium
GO:0007187 - G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

598443

NF1
Neurofibromin

2

1

Small-scale

0.624

High

839276

RPTOR
Regulatory-associated protein of mTOR

1

1

Small-scale

0.618

High

839294

ATX10
Ataxin-10

2

0

Small-scale

0.588

High

839270

CDK5
Cyclin-dependent kinase 5

1

0

Small-scale

0.586

High

412089

FYN
Tyrosine-protein kinase Fyn

1

4

Small-scale

0.586

High

807637

MAP1B
Microtubule-associated protein 1B

1

4

Small-scale

0.586

High

757514

IF4A3
Eukaryotic initiation factor 4A-III

1

1

High-throughput

0.541

High

839269

ACTB
Actin, cytoplasmic 1

1

5

High-throughput

0.541

High

839280

AP2M1
AP-2 complex subunit mu

1

3

High-throughput

0.541

High

839290

ABCA2
ATP-binding cassette sub-family A member 2

1

2

High-throughput

0.541

High

839292

TTYH1
Protein tweety homolog 1

1

2

High-throughput

0.541

High

839268

NOVA1
RNA-binding protein Nova-1

1

4

Small-scale

0.535

High

839278

CSN5
COP9 signalosome complex subunit 5

1

4

Small-scale

0.535

High

129081

SYT5
Synaptotagmin-5

1

0

High-throughput

0.518

High

380179

THY1
Thy-1 membrane glycoprotein

1

0

High-throughput

0.518

High

537537

AK1A1
Aldo-keto reductase family 1 member A1

1

0

High-throughput

0.518

High

674585

SC6A1
Sodium- and chloride-dependent GABA transporter 1

1

0

High-throughput

0.518

High

815352

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

High-throughput

0.518

High

839297

TMM98
Transmembrane protein 98

1

0

High-throughput

0.518

High

118708

AIP
AH receptor-interacting protein

1

1

High-throughput

0.494

High

551041

CHIN
N-chimaerin

1

3

High-throughput

0.494

High

839275

HDGR2
Hepatoma-derived growth factor-related protein 2

1

1

High-throughput

0.494

High

839284

DHRS1
Dehydrogenase/reductase SDR family member 1

1

1

High-throughput

0.494

High

839298

NRX3A
Neurexin-3

1

1

High-throughput

0.481

High

236410

RNBP6
Ran-binding protein 6

1

4

Small-scale

0.479

High

787421

MTOR
Serine/threonine-protein kinase mTOR

1

6

Small-scale

0.479

High

803879

NSF
Vesicle-fusing ATPase

1

2

Small-scale

0.479

High

839271

CLH1
Clathrin heavy chain 1

1

2

Small-scale

0.479

High

839279

TNPO1
Transportin-1

1

5

Small-scale

0.479

High

839267

DYN2
Dynamin-2

1

0

Small-scale

0.458

High

839282

COG3
Conserved oligomeric Golgi complex subunit 3

1

0

Small-scale

0.458

High

839283

EXOC2
Exocyst complex component 2

1

0

Small-scale

0.458

High

839295

NCDN
Neurochondrin

1

0

Small-scale

0.458

High

839293

NRX3B
Neurexin-3-beta

1

1

High-throughput

0.457

High

178133

IPO8
Importin-8

1

8

Small-scale

0.437

High

207911

XPOT
Exportin-T

1

4

Small-scale

0.437

High

226879

PRKN
E3 ubiquitin-protein ligase parkin

1

3

High-throughput

0.437

High

256737

CAND2
Cullin-associated NEDD8-dissociated protein 2

1

7

Small-scale

0.437

High

839272

ATM
Serine-protein kinase ATM

1

6

Small-scale

0.437

High

839273

ATR
Serine/threonine-protein kinase ATR

1

6

Small-scale

0.437

High

839285

SMG1
Serine/threonine-protein kinase SMG1

1

6

Small-scale

0.437

High

839286

CND3
Condensin complex subunit 3

1

1

Small-scale

0.437

High

839291

XPO4
Exportin-4

1

2

Small-scale

0.437

High

839296

COPG2
Coatomer subunit gamma-2

1

5

Small-scale

0.437

High

606865

IDS
Iduronate 2-sulfatase

1

0

High-throughput

0.282

High

839274

RUN3A
RUN domain-containing protein 3A

1

0

High-throughput

0.282

High

839277

PARP8
Protein mono-ADP-ribosyltransferase PARP8

1

0

High-throughput

0.282

High

839281

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.282

High

839287

CMS1
Protein CMSS1

1

0

High-throughput

0.282

High

839289

SRRT
Serrate RNA effector molecule homolog

1

0

High-throughput

0.282

High

839300

AP4S1
AP-4 complex subunit sigma-1

1

0

High-throughput

0.282

High

195894

TTI1
TELO2-interacting protein 1 homolog

1

0

Small-scale

0.249

Low

839288

TBCD
Tubulin-specific chaperone D

1

0

Small-scale

0.249

Low

839299

TELO2
Telomere length regulation protein TEL2 homolog

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024