Interactor 1: EYA2 (O00167)
Eyes absent homolog 2 (EC 3.1.3.48)
Gene: EYA2

Interactor 2: BAG3 (O95817)
BAG family molecular chaperone regulator 3 (BAG-3) (Bcl-2-associated athanogene 3) (Bcl-2-binding protein Bis) (Docking protein CAIR-1)
Gene: BAG3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.71 0.60 0.653

The method score is based on:

Property Details
Experiments 27880917, 32296183, unassigned1304
Identification Methods proximity labelling technology, two hybrid, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0097192 - extrinsic apoptotic signaling pathway in absence of ligand
Homologous interactions 2

Homologous interactions

Color coding for hit scores

1 538
Hs

1 575
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024