Protein: WDTC1
WD and tetratricopeptide repeats protein 1

Gene: WDTC1
Organism: Homo sapiens
Interactions: 144
UniProt ID: Q8N5D0

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0001701 - in utero embryonic development
GO:0004857 - enzyme inhibitor activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1082281

DDB1
DNA damage-binding protein 1

8

20

Small-scale

0.970

High

1032850

PHLP
Phosducin-like protein

2

5

High-throughput

0.811

High

1234407

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

2

14

High-throughput

0.802

High

1043102

CUL4A
Cullin-4A

10

20

Small-scale

0.754

High

1043455

CUL4B
Cullin-4B

4

20

Small-scale

0.703

High

1059451

NAA30
N-alpha-acetyltransferase 30

1

5

High-throughput

0.691

High

573365

TCPA
T-complex protein 1 subunit alpha

3

20

High-throughput

0.667

High

770929

TCPZ
T-complex protein 1 subunit zeta

3

20

High-throughput

0.667

High

943350

TCPB
T-complex protein 1 subunit beta

3

20

High-throughput

0.667

High

1234374

DDA1
DET1- and DDB1-associated protein 1

3

8

High-throughput

0.667

High

1234362

FBXW5
F-box/WD repeat-containing protein 5

1

0

High-throughput

0.656

High

826764

TCPG
T-complex protein 1 subunit gamma

2

20

High-throughput

0.628

High

843285

TCPD
T-complex protein 1 subunit delta

2

20

High-throughput

0.628

High

1089303

RHG44
Rho GTPase-activating protein 44

2

10

High-throughput

0.628

High

1234358

TCPW
T-complex protein 1 subunit zeta-2

2

20

High-throughput

0.628

High

1234373

TCPH
T-complex protein 1 subunit eta

2

20

High-throughput

0.628

High

1234383

EKI1
Ethanolamine kinase 1

2

2

High-throughput

0.628

High

147532

SOCS6
Suppressor of cytokine signaling 6

2

10

High-throughput

0.621

High

268175

EED
Polycomb protein EED

1

16

High-throughput

0.618

High

903365

WDR5
WD repeat-containing protein 5

1

18

High-throughput

0.618

High

929561

RACK1
Small ribosomal subunit protein RACK1

1

19

High-throughput

0.618

High

1123633

DCAF6
DDB1- and CUL4-associated factor 6

1

18

High-throughput

0.618

High

1146617

A16L1
Autophagy-related protein 16-1

1

19

High-throughput

0.618

High

1234352

WDTC1
WD and tetratricopeptide repeats protein 1

1

18

High-throughput

0.618

High

1234369

DNJC7
DnaJ homolog subfamily C member 7

1

19

High-throughput

0.618

High

1234379

UN45A
Protein unc-45 homolog A

1

20

High-throughput

0.618

High

1234393

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

9

High-throughput

0.618

High

1234399

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

2

High-throughput

0.618

High

1234400

FBW1B
F-box/WD repeat-containing protein 11

1

19

High-throughput

0.618

High

821313

TCPE
T-complex protein 1 subunit epsilon

2

20

High-throughput

0.611

High

157355

BCKD
Branched-chain alpha-ketoacid dehydrogenase kinase

3

3

High-throughput

0.609

High

947971

RT11
Small ribosomal subunit protein uS11m

3

9

High-throughput

0.609

High

1234380

GHC1
Mitochondrial glutamate carrier 1

3

8

High-throughput

0.609

High

1234405

NUDC
Nuclear migration protein nudC

2

18

High-throughput

0.584

High

1173378

STXB4
Syntaxin-binding protein 4

2

4

High-throughput

0.574

High

1234397

SEPT3
Neuronal-specific septin-3

2

12

High-throughput

0.574

High

1174058

UBP54
Inactive ubiquitin carboxyl-terminal hydrolase 54

1

11

High-throughput

0.553

High

197350

SERA
D-3-phosphoglycerate dehydrogenase

1

10

High-throughput

0.536

High

331392

APBA3
Amyloid-beta A4 precursor protein-binding family A member 3

1

3

High-throughput

0.536

High

795551

AL3B1
Aldehyde dehydrogenase family 3 member B1

1

11

High-throughput

0.536

High

897272

CSN2
COP9 signalosome complex subunit 2

1

11

High-throughput

0.536

High

1024185

CSN1
COP9 signalosome complex subunit 1

1

11

High-throughput

0.536

High

1033678

IKZF1
DNA-binding protein Ikaros

1

9

High-throughput

0.536

High

1234365

BOD1
Biorientation of chromosomes in cell division protein 1

1

2

High-throughput

0.536

High

1234366

TET5A
Terminal nucleotidyltransferase 5A

1

1

High-throughput

0.536

High

1234367

SPB11
Serpin B11

1

7

High-throughput

0.536

High

1234370

CSN8
COP9 signalosome complex subunit 8

1

2

High-throughput

0.536

High

1234377

UCK2
Uridine-cytidine kinase 2

1

2

High-throughput

0.536

High

1234389

DECR2
Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]

1

2

High-throughput

0.536

High

1234402

CSN3
COP9 signalosome complex subunit 3

1

10

High-throughput

0.536

High

146638

SOCS2
Suppressor of cytokine signaling 2

1

12

High-throughput

0.515

High

772056

VHL
von Hippel-Lindau disease tumor suppressor

1

3

High-throughput

0.515

High

1161241

TM10B
tRNA methyltransferase 10 homolog B

1

0

High-throughput

0.513

High

1234375

FUT8
Alpha-(1,6)-fucosyltransferase

1

0

High-throughput

0.513

High

1234395

CGBP1
CGG triplet repeat-binding protein 1

1

0

High-throughput

0.513

High

1087050

H2A2C
Histone H2A type 2-C

1

11

High-throughput

0.512

High

1234376

PG12A
Group XIIA secretory phospholipase A2

1

0

High-throughput

0.493

High

709266

GALNS
N-acetylgalactosamine-6-sulfatase

1

2

High-throughput

0.489

High

851149

PRELP
Prolargin

1

4

High-throughput

0.489

High

964672

IL5RA
Interleukin-5 receptor subunit alpha

1

9

High-throughput

0.489

High

1037560

PNOC
Prepronociceptin [Cleaved into: Nocistatin; Nociceptin

1

1

High-throughput

0.489

High

1234354

ZPLD1
Zona pellucida-like domain-containing protein 1

1

2

High-throughput

0.489

High

1234386

MED4
Mediator of RNA polymerase II transcription subunit 4

1

1

Small-scale

0.481

High

118763

AIP
AH receptor-interacting protein

1

20

High-throughput

0.479

High

136047

ACACB
Acetyl-CoA carboxylase 2

1

18

High-throughput

0.479

High

162990

XPO1
Exportin-1

1

20

High-throughput

0.479

High

171650

PFD6
Prefoldin subunit 6

1

6

High-throughput

0.479

High

172755

ZN185
Zinc finger protein 185

1

1

High-throughput

0.479

High

202663

TXNL1
Thioredoxin-like protein 1

1

18

High-throughput

0.479

High

228046

PRKN
E3 ubiquitin-protein ligase parkin

1

20

High-throughput

0.479

High

234246

PEPL
Periplakin

1

20

High-throughput

0.479

High

266385

TAD2A
Transcriptional adapter 2-alpha

1

16

High-throughput

0.479

High

306586

SCEL
Sciellin

1

1

High-throughput

0.479

High

319264

BRD1
Bromodomain-containing protein 1

1

11

High-throughput

0.479

High

323432

TTC4
Tetratricopeptide repeat protein 4

1

20

High-throughput

0.479

High

398273

PCCA
Propionyl-CoA carboxylase alpha chain, mitochondrial

1

16

High-throughput

0.479

High

398372

PCCB
Propionyl-CoA carboxylase beta chain, mitochondrial

1

20

High-throughput

0.479

High

416472

S10A9
Protein S100-A9

1

3

High-throughput

0.479

High

418456

NPM
Nucleophosmin

1

5

High-throughput

0.479

High

438351

HS90B
Heat shock protein HSP 90-beta

1

20

High-throughput

0.479

High

449311

LEG1
Galectin-1

1

9

High-throughput

0.479

High

513601

PYC
Pyruvate carboxylase, mitochondrial

1

18

High-throughput

0.479

High

551777

DESP
Desmoplakin

1

19

High-throughput

0.479

High

559829

H12
Histone H1.2

1

11

High-throughput

0.479

High

598227

FLNA
Filamin-A

1

12

High-throughput

0.479

High

779737

CCNF
Cyclin-F

1

9

High-throughput

0.479

High

806083

RL5
Large ribosomal subunit protein uL18

1

2

High-throughput

0.479

High

836463

5NTC
Cytosolic purine 5'-nucleotidase

1

1

High-throughput

0.479

High

858652

PPP5
Serine/threonine-protein phosphatase 5

1

7

High-throughput

0.479

High

882945

RBM11
Splicing regulator RBM11

1

10

High-throughput

0.479

High

901700

PFD3
Prefoldin subunit 3

1

7

High-throughput

0.479

High

921341

RBX1
E3 ubiquitin-protein ligase RBX1

1

6

High-throughput

0.479

High

972549

FKBP4
Peptidyl-prolyl cis-trans isomerase FKBP4

1

19

High-throughput

0.479

High

1024047

ACACA
Acetyl-CoA carboxylase 1

1

18

High-throughput

0.479

High

1042031

CUL3
Cullin-3

1

20

Small-scale

0.479

High

1049268

KEAP1
Kelch-like ECH-associated protein 1

1

3

High-throughput

0.479

High

1058191

LPIN1
Phosphatidate phosphatase LPIN1

1

1

High-throughput

0.479

High

1082872

CDC37
Hsp90 co-chaperone Cdc37

1

6

High-throughput

0.479

High

1084332

SRSF7
Serine/arginine-rich splicing factor 7

1

17

High-throughput

0.479

High

1085314

FSCN1
Fascin

1

1

High-throughput

0.479

High

1086217

H31T
Histone H3.1t

1

13

High-throughput

0.479

High

1087260

H2B2E
Histone H2B type 2-E

1

12

High-throughput

0.479

High

1113808

GRDN
Girdin

1

20

High-throughput

0.479

High

1134368

KPRP
Keratinocyte proline-rich protein

1

2

High-throughput

0.479

High

1173690

VP13C
Intermembrane lipid transfer protein VPS13C

1

3

High-throughput

0.479

High

1217404

NUDC3
NudC domain-containing protein 3

1

18

High-throughput

0.479

High

1221019

MSRB3
Methionine-R-sulfoxide reductase B3

1

1

High-throughput

0.479

High

1234353

KNL1
Kinetochore scaffold 1

1

2

High-throughput

0.479

High

1234356

PP4R1
Serine/threonine-protein phosphatase 4 regulatory subunit 1

1

8

High-throughput

0.479

High

1234357

NUDC2
NudC domain-containing protein 2

1

18

High-throughput

0.479

High

1234359

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

8

High-throughput

0.479

High

1234360

CSN5
COP9 signalosome complex subunit 5

1

14

High-throughput

0.479

High

1234361

GLMN
Glomulin

1

2

High-throughput

0.479

High

1234363

CHM4C
Charged multivesicular body protein 4c

1

6

High-throughput

0.479

High

1234368

PFD5
Prefoldin subunit 5

1

6

High-throughput

0.479

High

1234381

CSN7B
COP9 signalosome complex subunit 7b

1

6

High-throughput

0.479

High

1234382

CYBP
Calcyclin-binding protein

1

2

High-throughput

0.479

High

1234384

MCCB
Methylcrotonoyl-CoA carboxylase beta chain, mitochondrial

1

20

High-throughput

0.479

High

1234387

PFD4
Prefoldin subunit 4

1

5

High-throughput

0.479

High

1234391

PIHD1
PIH1 domain-containing protein 1

1

4

High-throughput

0.479

High

1234392

WHRN
Whirlin

1

3

High-throughput

0.479

High

1234394

CSN7A
COP9 signalosome complex subunit 7a

1

6

High-throughput

0.479

High

1234396

ZRAN1
Ubiquitin thioesterase ZRANB1

1

11

High-throughput

0.479

High

1234398

PFD2
Prefoldin subunit 2

1

5

High-throughput

0.479

High

1234403

SRRM2
Serine/arginine repetitive matrix protein 2

1

17

High-throughput

0.479

High

1234404

RUVB2
RuvB-like 2

1

6

High-throughput

0.479

High

166441

PUR4
Phosphoribosylformylglycinamidine synthase

1

0

High-throughput

0.458

High

1234364

KBP
KIF-binding protein

1

0

High-throughput

0.458

High

1234371

METH
Methionine synthase

1

0

High-throughput

0.458

High

1234388

SIAS
Sialic acid synthase

1

0

High-throughput

0.458

High

1234401

MED23
Mediator of RNA polymerase II transcription subunit 23

1

1

Small-scale

0.457

High

1184907

CSN6
COP9 signalosome complex subunit 6

1

7

High-throughput

0.445

High

327194

TXD12
Thioredoxin domain-containing protein 12

1

6

High-throughput

0.437

High

671868

PDIA3
Protein disulfide-isomerase A3

1

11

High-throughput

0.437

High

1217266

ANKY2
Ankyrin repeat and MYND domain-containing protein 2

1

12

High-throughput

0.437

High

1234385

ZCC17
Zinc finger CCHC domain-containing protein 17

1

6

High-throughput

0.437

High

1234390

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

8

Small-scale

0.437

High

1168310

PPR21
Protein phosphatase 1 regulatory subunit 21

2

0

High-throughput

0.328

High

1234372

MIPEP
Mitochondrial intermediate peptidase

2

0

High-throughput

0.328

High

272369

MTU1
Mitochondrial tRNA-specific 2-thiouridylase 1

1

0

High-throughput

0.279

Low

1234355

PXYP1
2-phosphoxylose phosphatase 1

1

0

High-throughput

0.279

Low

1234378

CHST5
Carbohydrate sulfotransferase 5

1

0

High-throughput

0.279

Low

1234406

COQ4
Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024