Protein: O61380
Eukaryotic translation initiation factor 4G1, isoform A (Eukaryotic translation initiation factor 4G1, isoform C) (FI02056p) (Translation initiation factor eIF4G)

Gene: O61380, eIF4G1
Organism: Drosophila melanogaster
Interactions: 39
UniProt ID: O61380

Gene Ontology (top 5):
GO:0000278 - mitotic cell cycle
GO:0000340 - RNA 7-methylguanosine cap binding
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0003743 - translation initiation factor activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

263474

IF4E
Eukaryotic translation initiation factor 4E1

15

19

Small-scale

0.982

High

263497

Q9VSG1
eIF-4F 25 kDa subunit

3

19

Small-scale

0.829

High

263494

Q9VRY0
eIF-4F 25 kDa subunit

2

19

Small-scale

0.767

High

263495

Q9VSB6
eIF-4F 25 kDa subunit

2

19

Small-scale

0.767

High

263503

Q9W5B3
eIF-4F 25 kDa subunit

2

19

Small-scale

0.767

High

263475

IF4A
Eukaryotic initiation factor 4A

1

20

Small-scale

0.656

High

263470

PABP
Polyadenylate-binding protein

3

14

Small-scale

0.640

High

263471

DDX6
ATP-dependent RNA helicase me31b

1

15

High-throughput

0.618

High

263480

Q7K4L8
RNA helicase

1

4

High-throughput

0.575

High

263484

Q8SY39
ATP-dependent RNA helicase DDX54

1

5

High-throughput

0.575

High

263473

FAS2
Fasciclin-2

2

3

High-throughput

0.574

High

263490

Q9VCC9
LD23779p

2

5

High-throughput

0.548

High

263492

INO80
Chromatin-remodeling ATPase INO80

1

7

High-throughput

0.514

High

263469

AUB
Protein aubergine

1

4

Small-scale

0.479

High

263476

SIMA
Protein similar

1

2

High-throughput

0.479

High

263478

DIAP2
Death-associated inhibitor of apoptosis 2

1

3

High-throughput

0.479

High

263485

FOXO
Forkhead box protein O

1

7

High-throughput

0.479

High

263486

CAPR1
Caprin homolog

1

6

Small-scale

0.479

High

263487

FMR1
Fragile X messenger ribonucleoprotein 1 homolog

1

10

Small-scale

0.479

High

263502

PDPK1
3-phosphoinositide-dependent protein kinase 1

1

3

High-throughput

0.479

High

263496

SRP09
Signal recognition particle 9 kDa protein

1

2

High-throughput

0.464

High

263483

AKT1
RAC serine/threonine-protein kinase

1

0

High-throughput

0.458

High

263488

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

High-throughput

0.458

High

55756

A1Z9K0
Uncharacterized protein, isoform B

1

5

High-throughput

0.445

High

263482

NITO
RNA-binding protein spenito

1

15

Small-scale

0.445

High

263489

LARP
La-related protein 1

1

14

High-throughput

0.445

High

120257

M9PD17
Gigas, isoform B

1

1

High-throughput

0.437

High

263472

FAT
Cadherin-related tumor suppressor

1

2

High-throughput

0.437

High

263477

Q24171
AT08303p

1

12

High-throughput

0.437

High

263493

Q9VP20
RING-type E3 ubiquitin transferase

1

2

Small-scale

0.437

High

263500

Q9VWJ6
FI03615p

1

3

High-throughput

0.437

High

263501

LSD2
Lipid storage droplets surface-binding protein 2

1

0

High-throughput

0.426

High

262703

TENM
Teneurin-m

1

2

High-throughput

0.407

High

263491

Q9VDK7
Signal recognition particle subunit SRP72

1

1

High-throughput

0.407

High

263499

TEY
Protein Teyrha-meyrha

1

0

High-throughput

0.265

Low

68864

MBD56
Methyl-CpG-binding domain protein 5/6 homolog sba

1

0

High-throughput

0.249

Low

263479

Q6NQZ7
LD40663p

1

0

High-throughput

0.249

Low

263481

Q7K519
GH16429p

1

0

Small-scale

0.249

Low

263498

Q9VUK7
RE36140p

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025