Protein: PPIH
Peptidyl-prolyl cis-trans isomerase H (PPIase H) (EC 5.2.1.8) (Rotamase H) (Small nuclear ribonucleoprotein particle-specific cyclophilin H) (CypH) (U-snRNP-associated cyclophilin SnuCyp-20) (USA-CYP)

Gene: PPIH
Organism: Homo sapiens
Interactions: 95
UniProt ID: O43447

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0000413 - protein peptidyl-prolyl isomerization
GO:0003755 - peptidyl-prolyl cis-trans isomerase activity
GO:0005654 - nucleoplasm
GO:0005681 - spliceosomal complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

196913

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

8

5

Small-scale

0.970

High

203522

RBM39
RNA-binding protein 39

2

4

High-throughput

0.789

High

203530

PRP8
Pre-mRNA-processing-splicing factor 8

2

3

High-throughput

0.789

High

203549

PRP18
Pre-mRNA-splicing factor 18

2

1

High-throughput

0.783

High

203523

SART3
Squamous cell carcinoma antigen recognized by T-cells 3

2

10

High-throughput

0.776

High

203502

FUS
RNA-binding protein FUS

1

7

High-throughput

0.691

High

203521

HNRPD
Heterogeneous nuclear ribonucleoprotein D0

1

6

High-throughput

0.691

High

203527

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

4

High-throughput

0.691

High

203551

RBM42
RNA-binding protein 42

1

4

High-throughput

0.691

High

203515

XIAP
E3 ubiquitin-protein ligase XIAP

3

2

High-throughput

0.671

High

203487

MYC
Myc proto-oncogene protein

3

7

High-throughput

0.640

High

203503

HD
Huntingtin

2

1

High-throughput

0.621

High

203478

PPIH
Peptidyl-prolyl cis-trans isomerase H

1

5

Small-scale

0.621

High

203492

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

4

High-throughput

0.618

High

203528

LARP7
La-related protein 7

1

3

High-throughput

0.618

High

203536

THOC4
THO complex subunit 4

1

1

High-throughput

0.618

High

203547

N42L2
NEDD4-binding protein 2-like 2

3

1

High-throughput

0.616

High

203524

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

2

5

High-throughput

0.611

High

203542

LNX1
E3 ubiquitin-protein ligase LNX

2

5

High-throughput

0.606

High

203558

UBQL2
Ubiquilin-2

2

3

High-throughput

0.606

High

203500

VCAM1
Vascular cell adhesion protein 1

2

3

High-throughput

0.601

High

203565

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

2

4

Small-scale

0.601

High

203566

LSM4
U6 snRNA-associated Sm-like protein LSm4

2

4

High-throughput

0.584

High

203534

DOK3
Docking protein 3

2

0

High-throughput

0.580

High

203552

NIF3L
NIF3-like protein 1

2

0

High-throughput

0.580

High

202335

PRPF3
U4/U6 small nuclear ribonucleoprotein Prp3

2

0

Small-scale

0.561

High

203540

LNX2
Ligand of Numb protein X 2

1

5

High-throughput

0.560

High

203493

RU1C
U1 small nuclear ribonucleoprotein C

1

1

High-throughput

0.536

High

203495

TOP1
DNA topoisomerase 1

1

3

High-throughput

0.536

High

203497

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

1

2

High-throughput

0.536

High

203504

KI67
Proliferation marker protein Ki-67

1

7

High-throughput

0.536

High

203506

SOX2
Transcription factor SOX-2

1

5

High-throughput

0.536

High

203510

RUXF
Small nuclear ribonucleoprotein F

1

5

High-throughput

0.536

High

203512

SMD2
Small nuclear ribonucleoprotein Sm D2

1

1

High-throughput

0.536

High

203516

SSRP1
FACT complex subunit SSRP1

1

6

High-throughput

0.536

High

203518

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

6

High-throughput

0.536

High

203519

CUL3
Cullin-3

1

4

High-throughput

0.536

High

203525

SF3A1
Splicing factor 3A subunit 1

1

5

High-throughput

0.536

High

203539

PACE1
Protein-associating with the carboxyl-terminal domain of ezrin

1

1

High-throughput

0.536

High

203554

DDX21
Nucleolar RNA helicase 2

1

7

High-throughput

0.536

High

203559

LSM7
U6 snRNA-associated Sm-like protein LSm7

1

5

High-throughput

0.536

High

203533

MEPCE
7SK snRNA methylphosphate capping enzyme

2

3

High-throughput

0.533

High

203517

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

4

High-throughput

0.515

High

203499

XRCC1
DNA repair protein XRCC1

1

0

High-throughput

0.513

High

203486

BAG2
BAG family molecular chaperone regulator 2

1

1

High-throughput

0.508

High

203509

NH2L1
NHP2-like protein 1

1

2

Small-scale

0.481

High

203544

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

1

1

Small-scale

0.481

High

148165

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.479

High

170177

TIF1A
Transcription intermediary factor 1-alpha

1

1

High-throughput

0.479

High

203479

NUPR1
Nuclear protein 1

1

1

High-throughput

0.479

High

203480

BRD4
Bromodomain-containing protein 4

1

2

High-throughput

0.479

High

203482

RECQ4
ATP-dependent DNA helicase Q4

1

7

High-throughput

0.479

High

203485

LSM8
U6 snRNA-associated Sm-like protein LSm8

1

5

High-throughput

0.479

High

203488

RASN
GTPase NRas

1

6

High-throughput

0.479

High

203489

FINC
Fibronectin

1

3

High-throughput

0.479

High

203490

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

3

High-throughput

0.479

High

203491

MYCN
N-myc proto-oncogene protein

1

7

High-throughput

0.479

High

203494

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

3

High-throughput

0.479

High

203496

ITA4
Integrin alpha-4

1

1

High-throughput

0.479

High

203498

EGR1
Early growth response protein 1

1

1

High-throughput

0.479

High

203501

BRD2
Bromodomain-containing protein 2

1

2

High-throughput

0.479

High

203505

RECQ1
ATP-dependent DNA helicase Q1

1

7

High-throughput

0.479

High

203511

LSM6
U6 snRNA-associated Sm-like protein LSm6

1

5

High-throughput

0.479

High

203513

H4
Histone H4

1

1

High-throughput

0.479

High

203531

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.479

High

203532

PAXI1
PAX-interacting protein 1

1

3

High-throughput

0.479

High

203535

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

7

High-throughput

0.479

High

203537

ZCH18
Zinc finger CCCH domain-containing protein 18

1

11

High-throughput

0.479

High

203541

ZGPAT
Zinc finger CCCH-type with G patch domain-containing protein

1

1

Small-scale

0.479

High

203545

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

3

High-throughput

0.479

High

203546

ESR2
Estrogen receptor beta

1

9

High-throughput

0.479

High

203548

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.479

High

203556

OLA1
Obg-like ATPase 1

1

1

High-throughput

0.479

High

203557

ZRAN1
Ubiquitin thioesterase ZRANB1

1

4

High-throughput

0.479

High

203560

TNIK
TRAF2 and NCK-interacting protein kinase

1

1

High-throughput

0.479

High

203561

FZR1
Fizzy-related protein homolog

1

3

High-throughput

0.479

High

203563

LSM2
U6 snRNA-associated Sm-like protein LSm2

1

4

High-throughput

0.479

High

203564

TRRAP
Transformation/transcription domain-associated protein

1

3

High-throughput

0.479

High

122383

MEN1
Menin

1

0

High-throughput

0.458

High

203483

MET18
Histidine protein methyltransferase 1 homolog

1

0

High-throughput

0.458

High

203508

FOXA1
Hepatocyte nuclear factor 3-alpha

1

0

High-throughput

0.458

High

203514

RL32
Large ribosomal subunit protein eL32

1

0

High-throughput

0.458

High

203538

SKA3
Spindle and kinetochore-associated protein 3

1

0

Small-scale

0.458

High

203543

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

203550

B9D2
B9 domain-containing protein 2

1

0

High-throughput

0.458

High

203555

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

203481

WBP4
WW domain-binding protein 4

1

4

Small-scale

0.457

High

203520

DYR1A
Dual specificity tyrosine-phosphorylation-regulated kinase 1A

1

5

High-throughput

0.445

High

203526

SF01
Splicing factor 1

1

1

High-throughput

0.445

High

203529

LITD1
LINE-1 type transposase domain-containing protein 1

1

2

High-throughput

0.445

High

203507

CEBPA
CCAAT/enhancer-binding protein alpha

1

5

High-throughput

0.408

High

203484

PTBP3
Polypyrimidine tract-binding protein 3

1

2

High-throughput

0.407

High

203553

BPIA1
BPI fold-containing family A member 1

2

0

High-throughput

0.316

High

203562

RL26L
Ribosomal protein uL24-like

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024