Protein: CLCN7
H(+)/Cl(-) exchange transporter 7 (Chloride channel 7 alpha subunit) (Chloride channel protein 7) (ClC-7)

Gene: CLCN7
Organism: Homo sapiens
Interactions: 137
UniProt ID: P51798

Gene Ontology (top 5):
GO:0005247 - voltage-gated chloride channel activity
GO:0005254 - chloride channel activity
GO:0005524 - ATP binding
GO:0005765 - lysosomal membrane
GO:0015108 - chloride transmembrane transporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

850392

OSTM1
Osteopetrosis-associated transmembrane protein 1

4

1

Small-scale

0.910

High

121131

LEG8
Galectin-8

3

8

High-throughput

0.667

High

207546

RNF13
E3 ubiquitin-protein ligase RNF13

3

0

High-throughput

0.638

High

850403

MCLN3
Mucolipin-3

3

0

High-throughput

0.638

High

844446

RAB5C
Ras-related protein Rab-5C

2

2

High-throughput

0.611

High

310270

LYPD3
Ly6/PLAUR domain-containing protein 3

3

1

High-throughput

0.609

High

850432

LYVE1
Lymphatic vessel endothelial hyaluronic acid receptor 1

2

1

High-throughput

0.606

High

850371

VAC14
Protein VAC14 homolog

2

0

High-throughput

0.602

High

850416

MANS1
MANSC domain-containing protein 1

2

0

High-throughput

0.602

High

359778

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

3

2

High-throughput

0.586

High

348585

RASN
GTPase NRas

2

5

High-throughput

0.584

High

349990

RASK
GTPase KRas

2

5

High-throughput

0.584

High

850396

S66A2
Solute carrier family 66 member 2

2

0

High-throughput

0.580

High

850402

GDAP1
Ganglioside-induced differentiation-associated protein 1

2

0

High-throughput

0.580

High

850406

TLCD4
TLC domain-containing protein 4

2

0

High-throughput

0.580

High

850422

S38A7
Sodium-coupled neutral amino acid transporter 7

2

0

High-throughput

0.580

High

555102

CD44
CD44 antigen

2

1

High-throughput

0.574

High

390136

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

2

0

High-throughput

0.559

High

850387

TRI67
Tripartite motif-containing protein 67

1

2

High-throughput

0.553

High

131555

STK25
Serine/threonine-protein kinase 25

1

1

High-throughput

0.536

High

521818

CADH1
Cadherin-1

1

2

High-throughput

0.536

High

845415

RAB9A
Ras-related protein Rab-9A

2

4

High-throughput

0.533

High

850366

RHOB
Rho-related GTP-binding protein RhoB

2

9

High-throughput

0.533

High

793240

MUC18
Cell surface glycoprotein MUC18

1

0

High-throughput

0.517

High

126783

ACATN
Acetyl-coenzyme A transporter 1

1

0

High-throughput

0.513

High

196753

CYB5B
Cytochrome b5 type B

1

0

High-throughput

0.513

High

207032

XRCC3
DNA repair protein XRCC3

1

0

High-throughput

0.513

High

274969

RENR
Renin receptor

1

0

High-throughput

0.513

High

354684

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

0

High-throughput

0.513

High

503208

PPAL
Lysosomal acid phosphatase

1

0

High-throughput

0.513

High

850359

CTXN1
Cortexin-1

1

0

High-throughput

0.513

High

850413

TTYH1
Protein tweety homolog 1

1

0

High-throughput

0.513

High

850430

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.513

High

216695

CREB3
Cyclic AMP-responsive element-binding protein 3

1

1

High-throughput

0.508

High

850398

S15A4
Solute carrier family 15 member 4

1

0

High-throughput

0.493

High

850378

GLE1
mRNA export factor GLE1

1

0

High-throughput

0.493

High

234008

O10H2
Olfactory receptor 10H2

1

1

High-throughput

0.489

High

850376

LEG9B
Galectin-9B

1

8

High-throughput

0.489

High

850379

TTMP
TPA-induced transmembrane protein

1

1

High-throughput

0.489

High

850431

PCDGL
Protocadherin gamma-C4

1

1

High-throughput

0.489

High

850358

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

High-throughput

0.481

High

167873

NPC1
NPC intracellular cholesterol transporter 1

1

1

High-throughput

0.479

High

169415

BET1
BET1 homolog

1

1

High-throughput

0.479

High

178444

STX7
Syntaxin-7

1

1

High-throughput

0.479

High

506935

LAMP1
Lysosome-associated membrane glycoprotein 1

1

2

High-throughput

0.479

High

525873

IFM1
Interferon-induced transmembrane protein 1

1

1

High-throughput

0.479

High

527360

LAMP2
Lysosome-associated membrane glycoprotein 2

1

2

High-throughput

0.479

High

592169

RAB5A
Ras-related protein Rab-5A

1

2

High-throughput

0.479

High

595155

LMNB1
Lamin-B1

1

2

High-throughput

0.479

High

844827

RAB7A
Ras-related protein Rab-7a

1

4

High-throughput

0.479

High

850361

CDC42
Cell division control protein 42 homolog

1

9

High-throughput

0.479

High

850362

RAB2A
Ras-related protein Rab-2A

1

2

High-throughput

0.479

High

850367

RAC1
Ras-related C3 botulinum toxin substrate 1

1

8

High-throughput

0.479

High

850369

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.479

High

850372

STX4
Syntaxin-4

1

1

High-throughput

0.479

High

850408

SEC62
Translocation protein SEC62

1

1

High-throughput

0.479

High

850414

DNJC5
DnaJ homolog subfamily C member 5

1

1

High-throughput

0.479

High

850420

TMPS4
Transmembrane protease serine 4

1

2

High-throughput

0.479

High

850427

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.479

High

850428

MYO6
Unconventional myosin-VI

1

1

High-throughput

0.479

High

850429

LAMP3
Lysosome-associated membrane glycoprotein 3

1

2

High-throughput

0.479

High

850384

Q6P5T0
AQP7 protein

1

3

High-throughput

0.470

High

163779

AT2A1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1

1

0

High-throughput

0.458

High

273737

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.458

High

390789

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

0

High-throughput

0.458

High

544950

AMPN
Aminopeptidase N

1

0

High-throughput

0.458

High

648691

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.458

High

795080

SSRA
Translocon-associated protein subunit alpha

1

0

High-throughput

0.458

High

825361

LMAN1
Protein ERGIC-53

1

0

High-throughput

0.458

High

828964

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

0

High-throughput

0.458

High

838729

EMD
Emerin

1

0

High-throughput

0.458

High

847410

BAP31
B-cell receptor-associated protein 31

1

0

High-throughput

0.458

High

850357

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.458

High

850364

ARF6
ADP-ribosylation factor 6

1

0

High-throughput

0.458

High

850365

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.458

High

850370

CAV1
Caveolin-1

1

0

High-throughput

0.458

High

850375

CAH9
Carbonic anhydrase 9

1

0

High-throughput

0.458

High

850382

LTOR1
Ragulator complex protein LAMTOR1

1

0

High-throughput

0.458

High

850399

CGAS
Cyclic GMP-AMP synthase

1

0

High-throughput

0.458

High

850407

PANX1
Pannexin-1

1

0

High-throughput

0.458

High

850411

DERL1
Derlin-1

1

0

High-throughput

0.458

High

850419

ST7
Suppressor of tumorigenicity 7 protein

1

0

High-throughput

0.458

High

850423

ELOV5
Very long chain fatty acid elongase 5

1

0

High-throughput

0.458

High

850424

TM216
Transmembrane protein 216

1

0

High-throughput

0.458

High

850425

B3GA1
Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1

1

0

High-throughput

0.458

High

146893

AQP7
Aquaporin-7

1

3

High-throughput

0.439

High

120357

RHOD
Rho-related GTP-binding protein RhoD

1

13

High-throughput

0.437

High

177846

TMPS2
Transmembrane protease serine 2

1

2

High-throughput

0.437

High

212771

STX6
Syntaxin-6

1

1

High-throughput

0.437

High

436214

RHOC
Rho-related GTP-binding protein RhoC

1

7

High-throughput

0.437

High

545274

RAC2
Ras-related C3 botulinum toxin substrate 2

1

7

High-throughput

0.437

High

564455

RHOQ
Rho-related GTP-binding protein RhoQ

1

9

High-throughput

0.437

High

591530

RAB3B
Ras-related protein Rab-3B

1

1

High-throughput

0.437

High

591779

RAB4A
Ras-related protein Rab-4A

1

2

High-throughput

0.437

High

850355

RND2
Rho-related GTP-binding protein RhoN

1

11

High-throughput

0.437

High

850360

RAC3
Ras-related C3 botulinum toxin substrate 3

1

8

High-throughput

0.437

High

850363

RHOA
Transforming protein RhoA

1

8

High-throughput

0.437

High

850368

RHOG
Rho-related GTP-binding protein RhoG

1

7

High-throughput

0.437

High

850373

RAB35
Ras-related protein Rab-35

1

1

High-throughput

0.437

High

850374

RHOH
Rho-related GTP-binding protein RhoH

1

9

High-throughput

0.437

High

850388

RHOU
Rho-related GTP-binding protein RhoU

1

11

High-throughput

0.437

High

850391

TM11B
Transmembrane protease serine 11B

1

2

High-throughput

0.437

High

850415

RHOJ
Rho-related GTP-binding protein RhoJ

1

9

High-throughput

0.437

High

850417

RHOF
Rho-related GTP-binding protein RhoF

1

10

High-throughput

0.437

High

850394

F177A
Protein FAM177A1

3

0

High-throughput

0.347

High

850404

BIRC7
Baculoviral IAP repeat-containing protein 7

3

0

High-throughput

0.347

High

778571

PMEL
Melanocyte protein PMEL

2

0

High-throughput

0.328

High

850381

MBLC2
Acyl-coenzyme A thioesterase MBLAC2

2

0

High-throughput

0.328

High

123375

GET1
Guided entry of tail-anchored proteins factor 1

2

0

High-throughput

0.316

High

583865

CD53
Leukocyte surface antigen CD53

2

0

High-throughput

0.316

High

723020

OPRM
Mu-type opioid receptor

2

0

High-throughput

0.316

High

850390

T179B
Transmembrane protein 179B

2

0

High-throughput

0.316

High

850401

LHPL5
LHFPL tetraspan subfamily member 5 protein

2

0

High-throughput

0.316

High

850426

KCNN3
Small conductance calcium-activated potassium channel protein 3

2

0

High-throughput

0.316

High

121460

TR10A
Tumor necrosis factor receptor superfamily member 10A

1

0

High-throughput

0.279

Low

850356

BIEA
Biliverdin reductase A

1

0

High-throughput

0.279

Low

850377

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

0

High-throughput

0.279

Low

850380

CSCL2
CSC1-like protein 2

1

0

High-throughput

0.279

Low

850385

SAMD1
Sterile alpha motif domain-containing protein 1

1

0

High-throughput

0.279

Low

850386

LRC55
Leucine-rich repeat-containing protein 55

1

0

High-throughput

0.279

Low

850405

TET5A
Terminal nucleotidyltransferase 5A

1

0

High-throughput

0.279

Low

850409

TMM47
Transmembrane protein 47

1

0

High-throughput

0.279

Low

850418

RXFP1
Relaxin receptor 1

1

0

High-throughput

0.279

Low

850389

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

0

High-throughput

0.268

Low

171205

CTDSL
CTD small phosphatase-like protein

1

0

High-throughput

0.249

Low

205194

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

351997

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.249

Low

386350

P53
Cellular tumor antigen p53

1

0

High-throughput

0.249

Low

669937

MARCS
Myristoylated alanine-rich C-kinase substrate

1

0

High-throughput

0.249

Low

850383

TECT3
Tectonic-3

1

0

High-throughput

0.249

Low

850393

TMM17
Transmembrane protein 17

1

0

High-throughput

0.249

Low

850395

CXD3
Gap junction delta-3 protein

1

0

High-throughput

0.249

Low

850400

DHB11
Estradiol 17-beta-dehydrogenase 11

1

0

High-throughput

0.249

Low

850410

GORS1
Golgi reassembly-stacking protein 1

1

0

High-throughput

0.249

Low

850412

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

1

0

High-throughput

0.249

Low

850421

OTULL
Inactive ubiquitin thioesterase OTULINL

1

0

High-throughput

0.249

Low

850397

RYBP
RING1 and YY1-binding protein

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024