Protein: Q0E8S4
Semaphorin-1A (Semaphorin-I)

Gene: Q0E8S4, Sema1a
Organism: Drosophila melanogaster
Interactions: 106
UniProt ID: Q0E8S4

Gene Ontology (top 5):
GO:0007399 - nervous system development
GO:0016020 - membrane
GO:0030154 - cell differentiation
GO:0030215 - semaphorin receptor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

54418

A1Z8J5
Shavenoid, isoform A

1

1

High-throughput

0.484

High

55685

A1Z9J3
Short stop, isoform H

1

2

High-throughput

0.484

High

746481

CYA1
Adenylate cyclase 1

1

3

High-throughput

0.484

High

778186

PTP10
Tyrosine-protein phosphatase 10D

1

3

High-throughput

0.484

High

1069491

RYR
Ryanodine receptor

1

4

High-throughput

0.484

High

1069537

Q9VRG4
ATP binding cassette subfamily A member 3, isoform B

1

4

High-throughput

0.484

High

1069562

STUM
Protein stum

1

1

High-throughput

0.484

High

52516

A1Z6Z9
Dilute class unconventional myosin, isoform A

1

1

High-throughput

0.445

High

479715

INSR
Insulin-like receptor

1

15

High-throughput

0.445

High

56054

A1Z9S6

1

9

High-throughput

0.442

High

57181

A1ZAV3
Misexpression suppressor of ras 4, isoform A

1

2

High-throughput

0.442

High

705007

EXU
Maternal protein exuperantia

1

1

High-throughput

0.442

High

753704

FAT
Cadherin-related tumor suppressor

1

5

High-throughput

0.442

High

828073

LA
La protein homolog

1

1

High-throughput

0.442

High

852485

CADF
Cofilin/actin-depolymerizing factor homolog

1

1

High-throughput

0.442

High

875347

DIA
Protein diaphanous

1

1

High-throughput

0.442

High

904449

HYD
E3 ubiquitin-protein ligase hyd

1

1

High-throughput

0.442

High

1069493

Q3YMU0
Protein disulfide-isomerase

1

3

High-throughput

0.442

High

1069495

Q7JUV6
GH06739p

1

3

High-throughput

0.442

High

1069496

Q7K4X4
GH24095p

1

3

High-throughput

0.442

High

1069497

Q7KND8
FI09619p

1

1

High-throughput

0.442

High

1069498

MICAL
[F-actin]-monooxygenase Mical

1

3

High-throughput

0.442

High

1069500

Q8IM86
Unc-13, isoform B

1

3

High-throughput

0.442

High

1069501

Q8IMW2
ubiquitinyl hydrolase 1

1

3

High-throughput

0.442

High

1069505

DOM
Helicase domino

1

3

High-throughput

0.442

High

1069507

Q9V3M9
Tektin

1

2

High-throughput

0.442

High

1069509

APLP
Apolipophorins

1

1

High-throughput

0.442

High

1069513

Q9VAV5
Dynein-1, subspecies f

1

8

High-throughput

0.442

High

1069514

Q9VC41
FI03419p

1

3

High-throughput

0.442

High

1069515

ANKHM
Ankyrin repeat and KH domain-containing protein mask

1

1

High-throughput

0.442

High

1069517

Q9VDG0
Dynein heavy chain at 93AB, isoform B

1

8

High-throughput

0.442

High

1069518

Q9VF02
Helicase 89B, isoform B

1

7

High-throughput

0.442

High

1069521

Q9VJ35
LD01527p

1

6

High-throughput

0.442

High

1069522

CADN2
Putative neural-cadherin 2

1

5

High-throughput

0.442

High

1069523

Q9VJC3
Cilia- and flagella-associated protein 91

1

1

High-throughput

0.442

High

1069525

TOR
Serine/threonine-protein kinase mTor

1

12

High-throughput

0.442

High

1069527

C2D1
Coiled-coil and C2 domain-containing protein 1-like

1

2

High-throughput

0.442

High

1069528

POE
Protein purity of essence

1

3

High-throughput

0.442

High

1069531

Q9VME5
Slow as molasses, isoform B

1

1

High-throughput

0.442

High

1069532

Q9VMS2
Nuclear receptor coactivator 6, isoform C

1

2

High-throughput

0.442

High

1069534

Q9VNH2
GM13341p

1

1

High-throughput

0.442

High

1069535

Q9VPL9
FI24801p1

1

3

High-throughput

0.442

High

1069536

Q9VPR0
LP14662p

1

2

High-throughput

0.442

High

1069538

TONSL
Tonsoku-like protein

1

4

High-throughput

0.442

High

1069539

Q9VSH1
GH01354p

1

1

High-throughput

0.442

High

1069540

PUS7
Pseudouridylate synthase 7 homolog

1

1

High-throughput

0.442

High

1069543

Q9VUB5
UpSET, isoform A

1

1

High-throughput

0.442

High

1069545

Q9VV82
Artemis, isoform A

1

3

High-throughput

0.442

High

1069547

Q9VVP2
MIP25823p1

1

1

High-throughput

0.442

High

1069548

FAT2
Fat-like cadherin-related tumor suppressor homolog

1

6

High-throughput

0.442

High

1069549

Q9VWZ3
Dynein heavy chain at 16F

1

8

High-throughput

0.442

High

1069550

Q9VX92
Rho GTPase activating protein at 15B, isoform C

1

5

High-throughput

0.442

High

1069554

Q9VZ77
Dynein, axonemal, heavy chain 3, isoform D

1

9

High-throughput

0.442

High

1069555

Q9VZF5
Kinesin-like protein

1

2

High-throughput

0.442

High

1069557

Q9W053
Zormin, isoform F

1

5

High-throughput

0.442

High

1069559

INT1
Integrator complex subunit 1

1

1

High-throughput

0.442

High

1069561

Q9W246
Uncharacterized protein

1

1

High-throughput

0.442

High

1069563

PANX
Protein panoramix

1

1

High-throughput

0.442

High

1069565

ZDHC8
Palmitoyltransferase ZDHHC8

1

3

High-throughput

0.442

High

1069566

Q9W3W6
Small ovary, isoform A

1

4

High-throughput

0.442

High

1069567

Q9W451
Female sterile

1

1

High-throughput

0.442

High

1069568

RTEL1
Regulator of telomere elongation helicase 1 homolog

1

1

High-throughput

0.442

High

1069569

Q9W4X4
Phosphatidylinositol 4-kinase alpha

1

5

High-throughput

0.442

High

1069570

FUTSC
Microtubule-associated protein futsch

1

10

High-throughput

0.442

High

1069571

RHGF
Rho GTPase-activating protein Graf

1

1

High-throughput

0.442

High

57047

A1ZAN6
Rho guanine nucleotide exchange factor 2, isoform D

1

2

High-throughput

0.407

High

262773

TENM
Teneurin-m

1

2

High-throughput

0.407

High

263810

CLOCK
Circadian locomoter output cycles protein kaput

1

1

High-throughput

0.407

High

900581

TAF1
Transcription initiation factor TFIID subunit 1

1

2

High-throughput

0.407

High

1019229

P91634
phosphatidylinositol 3-kinase

1

6

High-throughput

0.407

High

1024288

LAMA
Laminin subunit alpha

1

3

High-throughput

0.407

High

1069489

Q0E9F3
FI03652p

1

1

High-throughput

0.407

High

1069490

ISWI
Chromatin-remodeling complex ATPase chain Iswi

1

3

High-throughput

0.407

High

1069492

XPC
DNA repair protein complementing XP-C cells homolog

1

5

High-throughput

0.407

High

1069494

ATM
Serine/threonine-protein kinase ATM

1

9

High-throughput

0.407

High

1069499

TRA1
Transcription-associated protein 1

1

9

High-throughput

0.407

High

1069502

Q8SX22
RE68725p

1

9

High-throughput

0.407

High

1069503

Q95TU2
LD23187p

1

7

High-throughput

0.407

High

1069504

Q961C4
LD23619p

1

1

High-throughput

0.407

High

1069510

Q9V4D6
Asator, isoform D

1

2

High-throughput

0.407

High

1069511

PREP
Presequence protease, mitochondrial

1

2

High-throughput

0.407

High

1069512

SRRT
Serrate RNA effector molecule homolog

1

1

High-throughput

0.407

High

1069516

Q9VCE2
LD03179p

1

1

High-throughput

0.407

High

1069520

Q9VH10
TBC1 domain family member 30

1

3

High-throughput

0.407

High

1069524

CL190
Restin homolog

1

3

High-throughput

0.407

High

1069526

MPND
MPN domain-containing protein CG4751

1

1

High-throughput

0.407

High

1069529

Q9VM37
FI17813p1

1

1

High-throughput

0.407

High

1069530

Q9VM62
LD34181p

1

2

High-throughput

0.407

High

1069533

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

8

High-throughput

0.407

High

1069541

Q9VTH2
FI22313p1

1

2

High-throughput

0.407

High

1069542

CHRB
Protein charybde

1

1

High-throughput

0.407

High

1069544

Q9VUQ9
non-specific serine/threonine protein kinase

1

1

High-throughput

0.407

High

1069546

EXOC1
Exocyst complex component 1

1

1

High-throughput

0.407

High

1069551

Q9VXV3
Shattered

1

1

High-throughput

0.407

High

1069552

Q9VXW2
Probable ATP-dependent RNA helicase DDX46

1

3

High-throughput

0.407

High

1069553

Q9VZ30
C2H2-type domain-containing protein

1

5

High-throughput

0.407

High

1069556

HOBIT
Protein hobbit

1

1

High-throughput

0.407

High

1069564

CAPZA
F-actin-capping protein subunit alpha

1

1

High-throughput

0.407

High

607482

RS17
Small ribosomal subunit protein eS17

1

0

High-throughput

0.253

Low

809479

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.253

Low

898280

RL9
Large ribosomal subunit protein uL6

1

0

High-throughput

0.253

Low

1069506

PSMD6
26S proteasome non-ATPase regulatory subunit 6

1

0

High-throughput

0.253

Low

1069508

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

0

High-throughput

0.253

Low

1069560

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.253

Low

1069519

RS5B
Small ribosomal subunit protein uS7B

1

0

High-throughput

0.232

Low

1069558

Q9W1B9
Large ribosomal subunit protein uL11

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025