Protein: PKP4
Plakophilin-4 (p0071)

Gene: PKP4
Organism: Homo sapiens
Interactions: 150
UniProt ID: Q99569

Gene Ontology (top 5):
GO:0000922 - spindle pole
GO:0001533 - cornified envelope
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005856 - cytoskeleton

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

702793

CADH5
Cadherin-5

3

20

Small-scale

0.863

High

522149

CADH1
Cadherin-1

3

20

Small-scale

0.849

High

717300

CTNB1
Catenin beta-1

3

18

High-throughput

0.847

High

350478

RASK
GTPase KRas

3

20

High-throughput

0.827

High

877542

CADH8
Cadherin-8

2

20

High-throughput

0.811

High

1216817

ARMC8
Armadillo repeat-containing protein 8

2

8

Small-scale

0.806

High

348884

RASN
GTPase NRas

2

20

High-throughput

0.754

High

349587

RASH
GTPase HRas

2

20

High-throughput

0.754

High

915915

RHOB
Rho-related GTP-binding protein RhoB

2

20

High-throughput

0.754

High

370276

ESR1
Estrogen receptor

2

20

High-throughput

0.737

High

1301433

ERBIN
Erbin

5

14

Small-scale

0.724

High

877557

CAD12
Cadherin-12

1

20

High-throughput

0.691

High

995170

GOGA2
Golgin subfamily A member 2

3

8

High-throughput

0.675

High

793147

PE2R3
Prostaglandin E2 receptor EP3 subtype

3

5

High-throughput

0.667

High

1304589

CLC11
C-type lectin domain family 11 member A

3

2

High-throughput

0.667

High

164527

PDZD2
PDZ domain-containing protein 2

2

20

Small-scale

0.634

High

331402

APBA3
Amyloid-beta A4 precursor protein-binding family A member 3

2

19

High-throughput

0.628

High

601576

FGFR2
Fibroblast growth factor receptor 2

2

20

High-throughput

0.628

High

626755

NK1R
Substance-P receptor

2

9

High-throughput

0.628

High

1304585

CTNA3
Catenin alpha-3

2

20

High-throughput

0.628

High

1050039

SCRIB
Protein scribble homolog

2

20

Small-scale

0.621

High

580255

CADH2
Cadherin-2

1

20

Small-scale

0.621

High

1055850

DSC3
Desmocollin-3

1

20

Small-scale

0.621

High

120604

RHOD
Rho-related GTP-binding protein RhoD

1

20

High-throughput

0.618

High

318211

DIRA3
GTP-binding protein Di-Ras3

1

20

High-throughput

0.618

High

436476

RHOC
Rho-related GTP-binding protein RhoC

1

20

High-throughput

0.618

High

545582

RAC2
Ras-related C3 botulinum toxin substrate 2

1

20

High-throughput

0.618

High

564657

RHOQ
Rho-related GTP-binding protein RhoQ

1

20

High-throughput

0.618

High

818388

SOX2
Transcription factor SOX-2

1

18

High-throughput

0.618

High

852602

RND2
Rho-related GTP-binding protein RhoN

1

20

High-throughput

0.618

High

892554

RAC3
Ras-related C3 botulinum toxin substrate 3

1

20

High-throughput

0.618

High

894349

CDC42
Cell division control protein 42 homolog

1

20

High-throughput

0.618

High

895237

RAB2A
Ras-related protein Rab-2A

1

11

High-throughput

0.618

High

900835

RHOA
Transforming protein RhoA

1

20

High-throughput

0.618

High

901228

RND3
Rho-related GTP-binding protein RhoE

1

20

High-throughput

0.618

High

914306

RB11A
Ras-related protein Rab-11A

1

7

High-throughput

0.618

High

925553

RAC1
Ras-related C3 botulinum toxin substrate 1

1

20

High-throughput

0.618

High

951261

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.618

High

1070361

RAB35
Ras-related protein Rab-35

1

12

High-throughput

0.618

High

1076721

RHOH
Rho-related GTP-binding protein RhoH

1

20

High-throughput

0.618

High

1183516

RHOU
Rho-related GTP-binding protein RhoU

1

20

High-throughput

0.618

High

1269212

RND1
Rho-related GTP-binding protein Rho6

1

20

High-throughput

0.618

High

1269441

ESR2
Estrogen receptor beta

1

20

High-throughput

0.618

High

1296726

RHOV
Rho-related GTP-binding protein RhoV

1

20

High-throughput

0.618

High

1304574

RHOJ
Rho-related GTP-binding protein RhoJ

1

20

High-throughput

0.618

High

1304576

RHOF
Rho-related GTP-binding protein RhoF

1

20

High-throughput

0.618

High

819557

KCNJ5
G protein-activated inward rectifier potassium channel 4

2

0

High-throughput

0.602

High

1021555

DLG1
Disks large homolog 1

2

13

Small-scale

0.595

High

834336

PSN1
Presenilin-1

1

5

Small-scale

0.586

High

325863

LATS1
Serine/threonine-protein kinase LATS1

2

9

High-throughput

0.584

High

1117391

TM52B
Transmembrane protein 52B

2

1

High-throughput

0.574

High

1255256

HAVR2
Hepatitis A virus cellular receptor 2

2

1

High-throughput

0.574

High

734744

TRI23
E3 ubiquitin-protein ligase TRIM23

1

8

High-throughput

0.573

High

1304570

LZTS2
Leucine zipper putative tumor suppressor 2

1

15

High-throughput

0.573

High

1133700

RHG21
Rho GTPase-activating protein 21

2

8

High-throughput

0.571

High

158112

TX1B3
Tax1-binding protein 3

1

20

High-throughput

0.536

High

486315

CCL3
C-C motif chemokine 3

1

2

High-throughput

0.536

High

666344

NK3R
Neuromedin-K receptor

1

8

High-throughput

0.536

High

713866

RYK
Tyrosine-protein kinase RYK

1

20

High-throughput

0.536

High

794091

MATR3
Matrin-3

1

6

High-throughput

0.536

High

821808

NEST
Nestin

1

15

High-throughput

0.536

High

960941

CLH1
Clathrin heavy chain 1

1

3

High-throughput

0.536

High

970728

APBA1
Amyloid-beta A4 precursor protein-binding family A member 1

1

20

High-throughput

0.536

High

1079134

STK11
Serine/threonine-protein kinase STK11

1

1

High-throughput

0.536

High

1086135

AMHR2
Anti-Muellerian hormone type-2 receptor

1

4

High-throughput

0.536

High

1273823

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

10

High-throughput

0.536

High

1299900

CC85A
Coiled-coil domain-containing protein 85A

1

4

High-throughput

0.536

High

1304571

RGAP1
Rac GTPase-activating protein 1

1

6

High-throughput

0.536

High

1304582

GPC5B
G-protein coupled receptor family C group 5 member B

1

3

High-throughput

0.536

High

1304583

FLRT1
Leucine-rich repeat transmembrane protein FLRT1

1

5

High-throughput

0.536

High

1304587

CLC4A
C-type lectin domain family 4 member A

1

3

High-throughput

0.536

High

1304588

KCC2A
Calcium/calmodulin-dependent protein kinase type II subunit alpha

1

3

High-throughput

0.536

High

1304592

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

11

High-throughput

0.536

High

1304593

BACE2
Beta-secretase 2

1

1

High-throughput

0.536

High

1304594

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

2

High-throughput

0.536

High

246026

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.513

High

1291885

MRAP2
Melanocortin-2 receptor accessory protein 2

1

0

High-throughput

0.513

High

175136

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

6

High-throughput

0.501

High

441207

PTPRC
Receptor-type tyrosine-protein phosphatase C

1

20

High-throughput

0.501

High

942372

DLG4
Disks large homolog 4

1

12

High-throughput

0.501

High

1020110

PTPRJ
Receptor-type tyrosine-protein phosphatase eta

1

20

High-throughput

0.501

High

1246428

INADL
InaD-like protein

1

20

High-throughput

0.501

High

813141

CAZA2
F-actin-capping protein subunit alpha-2

1

3

High-throughput

0.489

High

1200431

URP2
Fermitin family homolog 3

1

2

High-throughput

0.489

High

1238112

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

9

High-throughput

0.489

High

1304581

GTSE1
G2 and S phase-expressed protein 1

1

2

High-throughput

0.489

High

1304578

OSGEP
tRNA N6-adenosine threonylcarbamoyltransferase

1

0

High-throughput

0.486

High

551814

DESP
Desmoplakin

1

11

Small-scale

0.481

High

1173215

PAXI1
PAX-interacting protein 1

1

8

High-throughput

0.481

High

1252426

LNX1
E3 ubiquitin-protein ligase LNX

1

20

Small-scale

0.481

High

1257130

UBS3B
Ubiquitin-associated and SH3 domain-containing protein B

1

5

High-throughput

0.481

High

164461

TRI66
Tripartite motif-containing protein 66

1

11

High-throughput

0.479

High

212980

STX6
Syntaxin-6

1

2

High-throughput

0.479

High

279685

FLOT1
Flotillin-1

1

4

High-throughput

0.479

High

305603

ZFPL1
Zinc finger protein-like 1

1

3

High-throughput

0.479

High

308999

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

347685

MYC
Myc proto-oncogene protein

1

11

High-throughput

0.479

High

411829

LCK
Tyrosine-protein kinase Lck

1

16

High-throughput

0.479

High

433962

LYN
Tyrosine-protein kinase Lyn

1

16

High-throughput

0.479

High

507199

LAMP1
Lysosome-associated membrane glycoprotein 1

1

9

High-throughput

0.479

High

547354

VATB1
V-type proton ATPase subunit B, kidney isoform

1

1

High-throughput

0.479

High

567234

CXA1
Gap junction alpha-1 protein

1

12

High-throughput

0.479

High

615823

GCSP
Glycine dehydrogenase

1

3

High-throughput

0.479

High

670172

MARCS
Myristoylated alanine-rich C-kinase substrate

1

9

High-throughput

0.479

High

716755

CTNA1
Catenin alpha-1

1

20

High-throughput

0.479

High

793439

MUC18
Cell surface glycoprotein MUC18

1

5

High-throughput

0.479

High

832660

MCM2
DNA replication licensing factor MCM2

1

15

High-throughput

0.479

High

856452

EFNA4
Ephrin-A4

1

3

High-throughput

0.479

High

872477

EPHA5
Ephrin type-A receptor 5

1

20

High-throughput

0.479

High

872696

EPHA4
Ephrin type-A receptor 4

1

20

High-throughput

0.479

High

876484

AFAD
Afadin

1

20

High-throughput

0.479

High

913065

ARF6
ADP-ribosylation factor 6

1

5

High-throughput

0.479

High

940540

CXAR
Coxsackievirus and adenovirus receptor

1

3

High-throughput

0.479

High

974988

CAV1
Caveolin-1

1

7

High-throughput

0.479

High

1017766

STX4
Syntaxin-4

1

5

High-throughput

0.479

High

1066575

KIF14
Kinesin-like protein KIF14

1

13

High-throughput

0.479

High

1069964

PTPRK
Receptor-type tyrosine-protein phosphatase kappa

1

20

High-throughput

0.479

High

1071686

KS6A2
Ribosomal protein S6 kinase alpha-2

1

8

High-throughput

0.479

High

1072580

EPHA7
Ephrin type-A receptor 7

1

20

High-throughput

0.479

High

1081579

NTRK3
NT-3 growth factor receptor

1

20

High-throughput

0.479

High

1084156

OCLN
Occludin

1

4

High-throughput

0.479

High

1152056

LTOR1
Ragulator complex protein LAMTOR1

1

3

High-throughput

0.479

High

1200325

DTX2
Probable E3 ubiquitin-protein ligase DTX2

1

6

High-throughput

0.479

High

1230345

CXD3
Gap junction delta-3 protein

1

12

High-throughput

0.479

High

1233425

NIN
Ninein

1

12

High-throughput

0.479

High

1256870

PARD3
Partitioning defective 3 homolog

1

20

High-throughput

0.479

High

1288571

ZBT10
Zinc finger and BTB domain-containing protein 10

1

4

Small-scale

0.479

High

1298924

LRRC7
Leucine-rich repeat-containing protein 7

1

14

Small-scale

0.479

High

1304572

DNJC5
DnaJ homolog subfamily C member 5

1

3

High-throughput

0.479

High

1304573

SAV1
Protein salvador homolog 1

1

16

High-throughput

0.479

High

1304575

PKHA4
Pleckstrin homology domain-containing family A member 4

1

20

High-throughput

0.479

High

1304577

E41LA
Band 4.1-like protein 4A

1

12

High-throughput

0.479

High

1304579

ANLN
Anillin

1

8

High-throughput

0.479

High

1304580

LATS2
Serine/threonine-protein kinase LATS2

1

11

High-throughput

0.479

High

1304584

ZRAN1
Ubiquitin thioesterase ZRANB1

1

13

High-throughput

0.479

High

1304586

BRPF3
Bromodomain and PHD finger-containing protein 3

1

9

High-throughput

0.479

High

306287

GBRAP
Gamma-aminobutyric acid receptor-associated protein

1

7

High-throughput

0.457

High

578356

PGAM1
Phosphoglycerate mutase 1

1

1

High-throughput

0.457

High

750886

VATA
V-type proton ATPase catalytic subunit A

1

2

High-throughput

0.445

High

1299725

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

9

High-throughput

0.445

High

1300660

MAGI1
Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1

1

20

High-throughput

0.445

High

1304590

ITM2B
Integral membrane protein 2B

1

4

High-throughput

0.445

High

132573

RCAS1
Receptor-binding cancer antigen expressed on SiSo cells

1

2

High-throughput

0.437

High

1203823

TMM17
Transmembrane protein 17

1

3

High-throughput

0.437

High

1283040

CK052
Uncharacterized protein C11orf52

1

5

High-throughput

0.437

High

1296875

SNX27
Sorting nexin-27

1

18

High-throughput

0.437

High

1304591

NINL
Ninein-like protein

1

11

High-throughput

0.437

High

1234811

ATPF2
ATP synthase mitochondrial F1 complex assembly factor 2

3

0

High-throughput

0.356

High

1101750

CF184
Cilia- and flagella-associated protein 184

1

0

High-throughput

0.279

Low

1165195

CP054
Transmembrane protein C16orf54

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024