Protein: M3K7
Mitogen-activated protein kinase kinase kinase 7 (EC 2.7.11.25) (TGF-beta-activated kinase 1) (dTAK1)

Gene: M3K7, Tak1
Organism: Drosophila melanogaster
Interactions: 129
UniProt ID: Q9V3Q6

Gene Ontology (top 5):
GO:0004674 - protein serine/threonine kinase activity
GO:0004706 - JUN kinase kinase kinase activity
GO:0004709 - MAP kinase kinase kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1237453

Q6NQZ7
LD40663p

3

0

Small-scale

0.623

High

119964

M9PBW9
Rhea, isoform G

1

9

High-throughput

0.618

High

263558

O61444
mitogen-activated protein kinase kinase

1

20

Small-scale

0.618

High

1464138

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

19

High-throughput

0.618

High

1464141

ANLN
Anillin

1

2

High-throughput

0.618

High

1464152

FLNA
Filamin-A

1

3

High-throughput

0.618

High

1464167

Q9VPU7
Arouser, isoform C

1

20

High-throughput

0.618

High

1464192

RHGF
Rho GTPase-activating protein Graf

1

7

High-throughput

0.618

High

117917

M9MRE1
PDGF- and VEGF-receptor related, isoform K

1

0

High-throughput

0.586

High

852507

CADF
Cofilin/actin-depolymerizing factor homolog

1

0

High-throughput

0.586

High

1464191

Q9XZ57
Eb1, isoform E

1

0

High-throughput

0.586

High

120789

M9PE30
Transgelin

1

2

High-throughput

0.553

High

1266716

IMD
Protein immune deficiency

1

0

Small-scale

0.480

High

56375

ZASP
PDZ and LIM domain protein Zasp

1

13

High-throughput

0.479

High

146135

CH60A
Heat shock protein 60A

1

1

High-throughput

0.479

High

232177

SMD3
Small nuclear ribonucleoprotein Sm D3

1

1

High-throughput

0.479

High

444096

TBA1
Tubulin alpha-1 chain

1

4

High-throughput

0.479

High

444125

TBA2
Tubulin alpha-2 chain

1

4

High-throughput

0.479

High

444150

TBA3
Tubulin alpha-3 chain

1

4

High-throughput

0.479

High

475820

EF1A1
Elongation factor 1-alpha 1

1

1

High-throughput

0.479

High

476481

TBB3
Tubulin beta-3 chain

1

4

High-throughput

0.479

High

509804

UBIQP
Polyubiquitin [Cleaved into: Ubiquitin]

1

5

Small-scale

0.479

High

538261

HSP7D
Heat shock 70 kDa protein cognate 4

1

4

High-throughput

0.479

High

559815

EF2
Eukaryotic translation elongation factor 2

1

1

High-throughput

0.479

High

633076

NCD
Protein claret segregational

1

6

High-throughput

0.479

High

715342

HSP7A
Heat shock 70 kDa protein cognate 1

1

4

High-throughput

0.479

High

715406

HSP7E
Heat shock 70 kDa protein cognate 5

1

8

High-throughput

0.479

High

834824

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

1

High-throughput

0.479

High

875254

TCPG
T-complex protein 1 subunit gamma

1

1

High-throughput

0.479

High

909946

SRP
Box A-binding factor

1

1

High-throughput

0.479

High

963865

SODC
Superoxide dismutase [Cu-Zn]

1

1

High-throughput

0.479

High

1040527

CACT
NF-kappa-B inhibitor cactus

1

6

High-throughput

0.479

High

1174368

CP190
Centrosome-associated zinc finger protein Cp190

1

2

High-throughput

0.479

High

1174600

TBB1
Tubulin beta-1 chain

1

4

High-throughput

0.479

High

1265806

Q7K3J0
T-complex protein 1 subunit theta

1

3

High-throughput

0.479

High

1267253

Q7KKI0
T-complex protein 1 subunit epsilon

1

1

High-throughput

0.479

High

1285541

Q86BB4
Transforming acidic coiled-coil protein, isoform E

1

1

High-throughput

0.479

High

1379196

Q961C5
Alphabet, isoform E

1

8

Small-scale

0.479

High

1463929

RUVB2
RuvB-like helicase 2

1

3

High-throughput

0.479

High

1464038

PRDX2
Peroxiredoxin 2

1

2

High-throughput

0.479

High

1464142

Q9V9Q4
LD43819p

1

1

High-throughput

0.479

High

1464145

LARP
La-related protein 1

1

1

High-throughput

0.479

High

1464149

ANKHM
Ankyrin repeat and KH domain-containing protein mask

1

1

High-throughput

0.479

High

1464155

RUVB1
RuvB-like helicase 1

1

3

High-throughput

0.479

High

1464156

TRBID
Ubiquitin thioesterase trabid

1

4

Small-scale

0.479

High

1464162

SOYB
Putative ATP-dependent RNA helicase SoYb

1

2

High-throughput

0.479

High

1464163

PIRAG
Zinc finger protein piragua

1

5

High-throughput

0.479

High

1464165

CH60C
60 kDa heat shock protein homolog 2, mitochondrial

1

1

High-throughput

0.479

High

1464168

Q9VRL8
Blanks

1

1

High-throughput

0.479

High

1464170

FRL
Formin-like protein

1

1

High-throughput

0.479

High

1464174

NU153
Nuclear pore complex protein Nup153

1

2

High-throughput

0.479

High

1464183

Q9W2U7
LP18708p

1

1

High-throughput

0.479

High

1464186

Q9W392
T-complex protein 1 subunit beta

1

1

High-throughput

0.479

High

1464187

Q9W3I9
GH01161p

1

19

Small-scale

0.479

High

1464189

Q9W5R5
Sarcolemmal membrane-associated protein

1

1

High-throughput

0.479

High

1464190

Q9XYR0
LD20987p

1

15

Small-scale

0.479

High

57823

A1ZB77
Uncharacterized protein, isoform J

1

0

High-throughput

0.458

High

95303

E1JIM0
Non-specific lethal 1, isoform E

1

0

High-throughput

0.458

High

263488

O61380
Eukaryotic translation initiation factor 4G1, isoform A

1

0

High-throughput

0.458

High

465892

CO4A1
Collagen alpha-1(IV) chain

1

0

High-throughput

0.458

High

604349

CATA
Catalase

1

0

High-throughput

0.458

High

628957

OTE
Otefin

1

0

High-throughput

0.458

High

652070

ATC1
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

1

0

High-throughput

0.458

High

654877

MA205
205 kDa microtubule-associated protein

1

0

High-throughput

0.458

High

770966

ATPA
ATP synthase subunit alpha, mitochondrial

1

0

High-throughput

0.458

High

1173928

ISWI
Chromatin-remodeling complex ATPase chain Iswi

1

0

High-throughput

0.458

High

1265659

DMAP1
DNA methyltransferase 1-associated protein 1

1

0

High-throughput

0.458

High

1266339

DGT5
Augmin complex subunit dgt5

1

0

High-throughput

0.458

High

1286184

LIG
Protein lingerer

1

0

High-throughput

0.458

High

1306766

CASP8
Caspase-8

1

0

High-throughput

0.458

High

1346191

CNBP
CCHC-type zinc finger nucleic acid binding protein

1

0

High-throughput

0.458

High

1427759

Q9GQR5
RH02809p

1

0

High-throughput

0.458

High

1440028

JUPIT
Microtubule-associated protein Jupiter

1

0

High-throughput

0.458

High

1463190

FADD
Fas-associated death domain protein

1

0

High-throughput

0.458

High

1464143

Q9VA35
CIN85 and CD2AP related, isoform A

1

0

High-throughput

0.458

High

1464148

MOC2B
Molybdopterin synthase catalytic subunit

1

0

High-throughput

0.458

High

1464150

VRET
Protein vreteno

1

0

High-throughput

0.458

High

1464153

Q9VFF0
Mitochondrial-processing peptidase subunit beta

1

0

High-throughput

0.458

High

1464158

Q9VHL2
T-complex protein 1 subunit eta

1

0

High-throughput

0.458

High

1464160

SMD2
Probable small nuclear ribonucleoprotein Sm D2

1

0

High-throughput

0.458

High

1464164

CUP
Protein cup

1

0

High-throughput

0.458

High

1464175

Q9VXQ5
Chaperonin containing TCP1 subunit 6

1

0

High-throughput

0.458

High

1464180

Q9W1H5
Decapping protein 1, isoform A

1

0

High-throughput

0.458

High

53067

A1Z7K2
FI03455p

1

3

High-throughput

0.437

High

55926

A1Z9M5
Titin

1

1

High-throughput

0.437

High

57128

A1ZAU6
FI05912p

1

1

High-throughput

0.437

High

121569

M9PFI0
CCR4-NOT transcription complex subunit 4

1

1

High-throughput

0.437

High

197816

HCD2
3-hydroxyacyl-CoA dehydrogenase type-2

1

2

High-throughput

0.437

High

427000

EF1A2
Elongation factor 1-alpha 2

1

1

High-throughput

0.437

High

856472

RL7A
Large ribosomal subunit protein eL8

1

2

High-throughput

0.437

High

938925

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.437

High

1055721

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.437

High

1175946

ADT
ADP,ATP carrier protein

1

1

High-throughput

0.437

High

1263890

Q7K012
Brahma associated protein 55kD

1

3

High-throughput

0.437

High

1457981

NH2L1
NHP2-like protein 1 homolog

1

2

High-throughput

0.437

High

1464139

PDIA6
Protein disulfide-isomerase A6 homolog

1

5

High-throughput

0.437

High

1464140

HCF
Host cell factor

1

5

High-throughput

0.437

High

1464147

Q9VBU9
40S ribosomal protein S27

1

1

High-throughput

0.437

High

1464154

MBDR2
Protein MBD-R2

1

2

High-throughput

0.437

High

1464166

Q9VP57
LD15904p

1

5

High-throughput

0.437

High

1464169

Q9VUB5
UpSET, isoform A

1

2

High-throughput

0.437

High

1464171

RS10B
Small ribosomal subunit protein eS10B

1

2

High-throughput

0.437

High

1464177

Q9VZF2
LD05244p

1

2

High-throughput

0.437

High

1464182

SGF29
SAGA-associated factor 29kDa

1

1

High-throughput

0.437

High

1464184

CUBN
Cubilin homolog

1

2

High-throughput

0.437

High

607497

RS17
Small ribosomal subunit protein eS17

1

0

High-throughput

0.249

Low

891985

TAF6
Transcription initiation factor TFIID subunit 6

1

0

High-throughput

0.249

Low

898339

RL22
Large ribosomal subunit protein eL22

1

0

High-throughput

0.249

Low

1013240

STIM
Stromal interaction molecule homolog

1

0

High-throughput

0.249

Low

1070781

Q0KHZ6
Electron transfer flavoprotein subunit beta

1

0

High-throughput

0.249

Low

1264029

NUP50
Nuclear pore complex protein Nup50

1

0

High-throughput

0.249

Low

1264816

Q7K180
LD02709p

1

0

High-throughput

0.249

Low

1344638

Q8SYU0
Coiled-coil domain-containing protein 43

1

0

High-throughput

0.249

Low

1376893

CATL1
Cathepsin L1

1

0

High-throughput

0.249

Low

1464144

S39AD
Zinc transporter ZIP13 homolog

1

0

High-throughput

0.249

Low

1464146

Q9VBU6
Protein RER1

1

0

High-throughput

0.249

Low

1464151

Q9VD58
Isocitric dehydrogenase subunit beta

1

0

High-throughput

0.249

Low

1464157

Q9VHH8
Beag

1

0

High-throughput

0.249

Low

1464159

Q9VHT6
Uncharacterized protein, isoform A

1

0

High-throughput

0.249

Low

1464161

Q9VJD1
Glucosidase 2 subunit beta

1

0

High-throughput

0.249

Low

1464172

Q9VWP5
Hat-trick, isoform D

1

0

High-throughput

0.249

Low

1464173

CREBB
Cyclic AMP response element-binding protein B

1

0

High-throughput

0.249

Low

1464176

Q9VZ00
FI19420p1

1

0

High-throughput

0.249

Low

1464178

Q9W0A8
FI01658p

1

0

High-throughput

0.249

Low

1464179

Q9W1B9
Large ribosomal subunit protein uL11

1

0

High-throughput

0.249

Low

1464181

RS16
Small ribosomal subunit protein uS9

1

0

High-throughput

0.249

Low

1464185

RS28
Small ribosomal subunit protein eS28

1

0

High-throughput

0.249

Low

1464188

Q9W3V2
FI19713p1

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025