Protein: H4
Histone H4

Gene: H4, His4
Organism: Drosophila melanogaster
Interactions: 81
UniProt ID: P84040

Gene Ontology (top 5):
GO:0000228 - nuclear chromosome
GO:0000786 - nucleosome
GO:0003677 - DNA binding
GO:0005694 - chromosome
GO:0006334 - nucleosome assembly

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1014795

CID
Histone H3-like centromeric protein cid

6

18

Small-scale

0.950

High

1014776

CAF1
Chromatin assembly factor 1 p55 subunit

5

11

Small-scale

0.836

High

145743

MOF
Histone acetyltransferase MOF

4

10

Small-scale

0.677

High

1014809

SMBT
Polycomb protein Sfmbt

3

11

Small-scale

0.667

High

777348

PARP
Poly [ADP-ribose] polymerase

3

5

Small-scale

0.664

High

1014773

Q0KIB3
Histone acetyltransferase type B catalytic subunit

1

5

Small-scale

0.648

High

1014774

ISWI
Chromatin-remodeling complex ATPase chain Iswi

1

16

Small-scale

0.647

High

380879

H2B
Histone H2B

1

20

Small-scale

0.621

High

477714

H2AV
Histone H2A.v

1

17

Small-scale

0.621

High

1014770

H2A
Histone H2A

1

15

Small-scale

0.621

High

1014787

Q8T0D3
Protein DEK

1

3

Small-scale

0.618

High

896151

MSL3
Protein male-specific lethal-3

2

5

Small-scale

0.602

High

1014802

KMT5A
Histone-lysine N-methyltransferase Set8

1

13

Small-scale

0.579

High

1014825

SUV42
Histone-lysine N-methyltransferase Suv4-20

1

5

Small-scale

0.579

High

594681

GROU
Protein groucho

1

7

Small-scale

0.553

High

1014771

DIF
Dorsal-related immunity factor Dif

2

1

High-throughput

0.542

High

1014806

SCM
Polycomb protein Scm

1

11

Small-scale

0.519

High

1014798

ANKHM
Ankyrin repeat and KH domain-containing protein mask

1

1

High-throughput

0.514

High

929152

DPOD1
DNA polymerase delta catalytic subunit

1

2

High-throughput

0.481

High

1014818

ATR
Serine/threonine-protein kinase ATR

1

6

High-throughput

0.481

High

54157

A1Z898
Chromatin assembly factor 1, p105 subunit

1

10

Small-scale

0.479

High

683675

PC
Polycomb group protein Pc

1

15

Small-scale

0.479

High

1014777

TAF9
Transcription initiation factor TFIID subunit 9

1

2

High-throughput

0.479

High

1014781

Q4V5A7
IP14655p

1

20

Small-scale

0.479

High

1014796

Q9V9T4
ATP-dependent chromatin assembly factor large subunit

1

20

Small-scale

0.479

High

1014799

Q9VCG6
IP14417p1

1

20

Small-scale

0.479

High

1014824

SPT6H
Transcription elongation factor SPT6

1

9

Small-scale

0.479

High

1014788

HIPPO
Serine/threonine-protein kinase hippo

1

3

High-throughput

0.464

High

1014819

GLD2B
Poly(A) RNA polymerase gld-2 homolog B

1

1

High-throughput

0.464

High

1014785

Q8MSC4
CG3509 protein

1

0

Small-scale

0.458

High

1014792

HDAC1
Histone deacetylase HDAC1

1

13

Small-scale

0.457

High

1014793

TIP60
Histone acetyltransferase Tip60

1

10

Small-scale

0.457

High

1014804

Q9VGW7
type I protein arginine methyltransferase

1

8

Small-scale

0.457

High

1014805

CARM1
Probable histone-arginine methyltransferase CARMER

1

9

Small-scale

0.457

High

1014826

EAF3
NuA4 complex subunit EAF3 homolog

1

7

Small-scale

0.457

High

235203

HTH
Homeobox protein homothorax

1

1

High-throughput

0.445

High

1014775

PCL
Polycomb protein Pcl

1

11

Small-scale

0.445

High

564962

ATNA
Sodium/potassium-transporting ATPase subunit alpha

1

5

High-throughput

0.442

High

1014772

ATPB
ATP synthase subunit beta, mitochondrial

1

2

High-throughput

0.442

High

1014807

DDX3
ATP-dependent RNA helicase bel

1

6

High-throughput

0.442

High

98443

F0JAG2
MIP27703p

1

3

High-throughput

0.439

High

1014822

RAD50
DNA repair protein RAD50

1

7

High-throughput

0.439

High

355892

O96689
FI11703p

1

1

Small-scale

0.437

High

567628

FSH
Homeotic protein female sterile

1

20

Small-scale

0.437

High

929376

FKB39
39 kDa FK506-binding nuclear protein

1

3

Small-scale

0.437

High

1014778

NLP
Nucleoplasmin-like protein

1

2

Small-scale

0.437

High

1014797

Q9VB52
LD05287p

1

12

Small-scale

0.437

High

1014808

Q9VK21
Kelch-like protein diablo

1

1

High-throughput

0.437

High

1014820

NU301
Nucleosome-remodeling factor subunit NURF301

1

20

Small-scale

0.437

High

1014791

Q94513
Boundary element associated factor

1

0

Small-scale

0.426

High

1014784

Q86BI3
Zinc-finger protein at 72D, isoform B

1

4

High-throughput

0.417

High

84579

LINT
Serine protease filzig

1

1

High-throughput

0.407

High

120638

M9PE01
cyclin-dependent kinase

1

3

High-throughput

0.407

High

583734

AMAL
Protein amalgam

1

1

High-throughput

0.407

High

882977

SDC
Syndecan

1

1

High-throughput

0.407

High

1014779

Q32KE1
RE04201p

1

4

High-throughput

0.407

High

1014783

GAR1
H/ACA ribonucleoprotein complex subunit 1

1

2

High-throughput

0.407

High

1014790

Q8WR53
Hephaestus, isoform B

1

6

High-throughput

0.407

High

1014794

Q9BN17
Echinoid

1

1

High-throughput

0.407

High

1014800

DMDA
Dystrophin, isoforms A/C/F/G/H

1

4

High-throughput

0.407

High

1014814

RIM2
Mitochondrial carrier protein Rim2

1

3

High-throughput

0.407

High

1014801

Q9VEN2
Chromosome alignment defect 1

1

0

Small-scale

0.306

High

1014780

Q4QQB9
LP21121p

1

0

High-throughput

0.265

Low

1014827

Q9Y165
E2 ubiquitin-conjugating enzyme

1

0

High-throughput

0.265

Low

95544

E2QCZ3
Diamond

1

0

Small-scale

0.249

Low

197989

AMYR
Alpha-amylase-related protein

1

0

High-throughput

0.249

Low

756742

FAS2
Fasciclin-2

1

0

High-throughput

0.249

Low

1014782

Q7K490
SD03973p

1

0

High-throughput

0.249

Low

1014803

Q9VGQ8
Arfaptin

1

0

High-throughput

0.249

Low

1014812

INT15
Integrator complex subunit 15

1

0

High-throughput

0.249

Low

1014816

PYRG
CTP synthase

1

0

High-throughput

0.249

Low

1014817

RETIN
Retinin

1

0

High-throughput

0.249

Low

1014815

AKIRN
Akirin

1

0

Small-scale

0.238

Low

460017

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.232

Low

1014786

Q8SXF0
Small ribosomal subunit protein uS9m

1

0

High-throughput

0.232

Low

1014789

Q8T3J1
SD02419p

1

0

High-throughput

0.232

Low

1014810

PIWI
Protein piwi

1

0

High-throughput

0.232

Low

1014811

Q9VNP3
Mesoderm-expressed 2, isoform B

1

0

High-throughput

0.232

Low

1014813

Q9VPX2
Major facilitator superfamily transporter 3

1

0

High-throughput

0.232

Low

1014821

Q9W1H6
GH04238p

1

0

High-throughput

0.232

Low

1014823

Q9W258
Babos, isoform A

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025