Protein: INAR1
Interferon alpha/beta receptor 1 (IFN-R-1) (IFN-alpha/beta receptor 1) (Cytokine receptor class-II member 1) (Cytokine receptor family 2 member 1) (CRF2-1) (Type I interferon receptor 1)

Gene: INAR1, IFNAR1
Organism: Homo sapiens
Interactions: 58
UniProt ID: P17181

Gene Ontology (top 5):
GO:0004905 - type I interferon receptor activity
GO:0005764 - lysosome
GO:0005770 - late endosome
GO:0005886 - plasma membrane
GO:0007259 - cell surface receptor signaling pathway via JAK-STAT

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

352865

IFNB
Interferon beta

4

8

Small-scale

0.887

High

566015

INAR2
Interferon alpha/beta receptor 2

3

2

Small-scale

0.827

High

566003

TYK2
Non-receptor tyrosine-protein kinase TYK2

13

20

Small-scale

0.759

High

566017

STAT2
Signal transducer and activator of transcription 2

7

15

Small-scale

0.745

High

352767

IFNA2
Interferon alpha-2

2

8

Small-scale

0.719

High

546430

INGR1
Interferon gamma receptor 1

1

15

High-throughput

0.691

High

560035

CTLA4
Cytotoxic T-lymphocyte protein 4

1

4

High-throughput

0.691

High

566013

NOTC1
Neurogenic locus notch homolog protein 1

1

8

High-throughput

0.691

High

566038

FBW1B
F-box/WD repeat-containing protein 11

4

4

Small-scale

0.652

High

566039

FBW1A
F-box/WD repeat-containing protein 1A

4

4

Small-scale

0.633

High

565998

JAK1
Tyrosine-protein kinase JAK1

2

20

Small-scale

0.619

High

566005

IFNA8
Interferon alpha-8

1

8

Small-scale

0.618

High

566028

LAP4B
Lysosomal-associated transmembrane protein 4B

2

1

High-throughput

0.606

High

566031

AP2M1
AP-2 complex subunit mu

2

0

Small-scale

0.576

High

181792

SOCS1
Suppressor of cytokine signaling 1

2

20

Small-scale

0.563

High

566036

KPCD2
Serine/threonine-protein kinase D2

1

2

Small-scale

0.561

High

121439

TR10A
Tumor necrosis factor receptor superfamily member 10A

1

5

High-throughput

0.536

High

154306

TR10B
Tumor necrosis factor receptor superfamily member 10B

1

8

High-throughput

0.536

High

212734

STX6
Syntaxin-6

1

1

High-throughput

0.536

High

499229

KIT
Mast/stem cell growth factor receptor Kit

1

9

High-throughput

0.536

High

507837

FGFR1
Fibroblast growth factor receptor 1

1

16

High-throughput

0.536

High

565996

FGFR2
Fibroblast growth factor receptor 2

1

17

High-throughput

0.536

High

565999

AVR2A
Activin receptor type-2A

1

11

High-throughput

0.536

High

566009

BMR1A
Bone morphogenetic protein receptor type-1A

1

11

High-throughput

0.536

High

566025

PTPRS
Receptor-type tyrosine-protein phosphatase S

1

18

High-throughput

0.536

High

566027

LRP10
Low-density lipoprotein receptor-related protein 10

1

6

High-throughput

0.536

High

566030

TR19L
Tumor necrosis factor receptor superfamily member 19L

1

5

High-throughput

0.536

High

566040

LRP12
Low-density lipoprotein receptor-related protein 12

1

7

High-throughput

0.536

High

566033

ANM1
Protein arginine N-methyltransferase 1

1

1

Small-scale

0.523

High

566012

STAT6
Signal transducer and activator of transcription 6

1

15

Small-scale

0.515

High

566029

UBP7
Ubiquitin carboxyl-terminal hydrolase 7

1

4

Small-scale

0.512

High

566016

UB2R1
Ubiquitin-conjugating enzyme E2 R1

1

1

Small-scale

0.501

High

566026

MK14
Mitogen-activated protein kinase 14

1

5

Small-scale

0.501

High

566011

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

15

Small-scale

0.500

High

449179

LEG1
Galectin-1

1

16

High-throughput

0.489

High

566000

CALX
Calnexin

1

5

High-throughput

0.489

High

566034

NFIP1
NEDD4 family-interacting protein 1

1

2

High-throughput

0.489

High

566001

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

4

Small-scale

0.479

High

566010

STAT3
Signal transducer and activator of transcription 3

1

16

Small-scale

0.479

High

566024

TRAF2
TNF receptor-associated factor 2

1

8

Small-scale

0.470

High

499515

CH60
60 kDa heat shock protein, mitochondrial

1

0

Small-scale

0.458

High

566014

BRCC3
Lys-63-specific deubiquitinase BRCC36

1

3

Small-scale

0.457

High

566021

RACK1
Small ribosomal subunit protein RACK1

1

2

Small-scale

0.457

High

566002

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

19

Small-scale

0.437

High

566004

1433B
14-3-3 protein beta/alpha

1

3

Small-scale

0.437

High

566006

GLYC
Serine hydroxymethyltransferase, cytosolic

1

2

Small-scale

0.437

High

566007

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

2

Small-scale

0.437

High

566019

HNRPK
Heterogeneous nuclear ribonucleoprotein K

1

2

Small-scale

0.437

High

566022

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

9

Small-scale

0.437

High

566023

EP300
Histone acetyltransferase p300

1

5

Small-scale

0.437

High

566037

TRI10
Tripartite motif-containing protein 10

1

3

Small-scale

0.437

High

566008

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.279

Low

566018

MFAP3
Microfibril-associated glycoprotein 3

1

0

High-throughput

0.279

Low

566032

GMCL1
Germ cell-less protein-like 1

1

0

High-throughput

0.279

Low

566035

PAXX
Protein PAXX

1

0

High-throughput

0.279

Low

537792

KPYM
Pyruvate kinase PKM

1

0

Small-scale

0.249

Low

565997

UBA1
Ubiquitin-like modifier-activating enzyme 1

1

0

Small-scale

0.249

Low

566020

1433E
14-3-3 protein epsilon

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024