Protein: ARL8
ADP-ribosylation factor-like protein 8 (Novel small G protein indispensable for equal chromosome segregation) (dGie)

Gene: ARL8
Organism: Drosophila melanogaster
Interactions: 108
UniProt ID: Q9VHV5

Gene Ontology (top 5):
GO:0000819 - sister chromatid segregation
GO:0001666 - response to hypoxia
GO:0003924 - GTPase activity
GO:0005525 - GTP binding
GO:0005737 - cytoplasm

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

958895

ARF1
ADP-ribosylation factor 1

2

19

High-throughput

0.737

High

829670

ARF4
ADP ribosylation factor 4

1

18

High-throughput

0.618

High

1022342

DIF
Dorsal-related immunity factor Dif

2

1

High-throughput

0.594

High

197097

O18332
FI01544p

2

18

High-throughput

0.571

High

304255

ERD2
ER lumen protein-retaining receptor

2

5

High-throughput

0.571

High

652095

ATC1
Calcium-transporting ATPase sarcoplasmic/endoplasmic reticulum type

2

11

High-throughput

0.571

High

715152

CLH
Clathrin heavy chain

2

4

High-throughput

0.571

High

1346270

Q8T8W3
AT21416p

2

3

High-throughput

0.571

High

1463767

RAB5
Ras-related protein Rab5

2

18

High-throughput

0.571

High

1465614

Q9V470
Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial

2

7

High-throughput

0.571

High

1476810

ACADM
Medium-chain specific acyl-CoA dehydrogenase, mitochondrial

2

3

High-throughput

0.571

High

304400

RIPL
RILP-like protein homolog

1

12

Small-scale

0.552

High

875285

TCPG
T-complex protein 1 subunit gamma

2

6

High-throughput

0.521

High

1011992

CCD1P
Probable cytochrome P450 12d1 proximal, mitochondrial

2

2

High-throughput

0.521

High

1176102

DX39B
ATP-dependent RNA helicase WM6

2

5

High-throughput

0.521

High

1267404

Q7KLX3
Translocon-associated protein subunit delta

2

5

High-throughput

0.521

High

1267722

Q7KMQ0
26S proteasome regulatory subunit 7

2

4

High-throughput

0.521

High

1268183

Q7KN94
Electron transfer flavoprotein subunit alpha

2

3

High-throughput

0.521

High

1376860

LDH
L-lactate dehydrogenase

2

3

High-throughput

0.521

High

1378485

Q95U38
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

2

7

High-throughput

0.521

High

1466751

Q9V9Q4
LD43819p

2

3

High-throughput

0.521

High

1476802

Q9VPR1
GH02075p

2

2

High-throughput

0.521

High

1476813

Q9VUZ0
Translocon-associated protein subunit beta

2

3

High-throughput

0.521

High

1476815

Q9VV75
AT02348p

2

4

High-throughput

0.521

High

1476820

Q9VWL0
Mec2

2

12

High-throughput

0.521

High

1476821

Q9VXQ5
Chaperonin containing TCP1 subunit 6

2

4

High-throughput

0.521

High

1476824

GALE
UDP-glucose 4-epimerase

2

5

High-throughput

0.521

High

1476825

Q9W3N1
RH59310p

2

9

High-throughput

0.521

High

1476797

Q9VMV9
Reticulon-like protein

1

14

High-throughput

0.494

High

1476798

Q9VMW2
Reticulon-like protein

1

14

High-throughput

0.481

High

197175

RAB2
Ras-related protein Rab-2

1

17

High-throughput

0.479

High

1172918

RHOL
Ras-like GTP-binding protein RhoL

1

20

High-throughput

0.479

High

1476795

MSS4
Guanine nucleotide exchange factor MSS4 homolog

1

4

High-throughput

0.479

High

1476807

Q9VRW5
MIP10846p1

1

1

High-throughput

0.464

High

1261307

Q7JQK2
RH04488p

1

1

High-throughput

0.451

High

304146

RAB7
Ras-related protein Rab7

1

18

High-throughput

0.445

High

355978

O96692
small monomeric GTPase

1

18

High-throughput

0.445

High

565033

ATNA
Sodium/potassium-transporting ATPase subunit alpha

1

11

High-throughput

0.445

High

782781

2AAA
Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit

1

2

High-throughput

0.445

High

828056

CDC42
Cdc42 homolog

1

20

High-throughput

0.445

High

911480

IMA
Importin subunit alpha

1

2

High-throughput

0.445

High

1070992

Q0KI98
Tryptophan--tRNA ligase, cytoplasmic

1

2

High-throughput

0.445

High

1285639

Q86BK8
Ras-related protein Rab-14

1

17

High-throughput

0.445

High

1464445

Q9V3V6
26S proteasome regulatory complex subunit p50

1

12

High-throughput

0.445

High

1464795

Q9V3Z4
GH11341p

1

1

High-throughput

0.445

High

1465454

Q9V455
Importin subunit alpha

1

2

High-throughput

0.445

High

1468474

Q9VAW3
glutamine--fructose-6-phosphate transaminase

1

1

High-throughput

0.445

High

1468644

Q9VAY2
Heat shock protein 83

1

10

High-throughput

0.445

High

1476786

Q9VI53
LD44267p

1

3

High-throughput

0.445

High

1476799

Q9VN44
FI07923p

1

5

High-throughput

0.445

High

1476800

CATF
Cathepsin F

1

2

High-throughput

0.445

High

1476801

RHEB
GTP-binding protein Rheb homolog

1

20

High-throughput

0.445

High

1476819

Q9VWI2
N(Alpha)-acetyltransferase 15/16, isoform A

1

2

High-throughput

0.445

High

1476822

Q9VZL3
very-long-chain enoyl-CoA reductase

1

5

High-throughput

0.445

High

1476823

Q9W0E4
Aminopeptidase

1

4

High-throughput

0.445

High

1476827

Q9W4N8
LD30122p

1

6

High-throughput

0.445

High

1304454

Q8IP97
Peroxin-19

1

1

High-throughput

0.439

High

1260768

Q76NQ0
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

11

High-throughput

0.437

High

1476792

ZUC
Mitochondrial cardiolipin hydrolase

1

3

High-throughput

0.437

High

1476803

GOLP3
Golgi phosphoprotein 3 homolog sauron

1

3

High-throughput

0.437

High

553697

APT
Adenine phosphoribosyltransferase

1

0

High-throughput

0.426

High

1465183

Q9V434
Asparagine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.426

High

1476808

Q9VS47
Lysosomal dipeptide transporter MFSD1

1

0

High-throughput

0.426

High

1476817

CLC
Clathrin light chain

1

0

High-throughput

0.426

High

53705

A1Z843
Nodal modulator 3

1

1

High-throughput

0.407

High

360573

COX2
Cytochrome c oxidase subunit 2

1

2

High-throughput

0.407

High

875017

PRS4
26S proteasome regulatory subunit 4

1

6

High-throughput

0.407

High

1070113

Q0E9E2
Pyruvate carboxylase

1

12

High-throughput

0.407

High

1071042

Q0KIB3
Histone acetyltransferase type B catalytic subunit

1

1

High-throughput

0.407

High

1176326

VATA2
V-type proton ATPase catalytic subunit A isoform 2

1

7

High-throughput

0.407

High

1236891

Q6NP35
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

11

High-throughput

0.407

High

1237028

Q6NP72
GEO09659p1

1

2

High-throughput

0.407

High

1264541

Q7K110
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

7

High-throughput

0.407

High

1265835

Q7K3J0
T-complex protein 1 subunit theta

1

3

High-throughput

0.407

High

1268721

CCD1D
Probable cytochrome P450 12d1 distal, mitochondrial

1

2

High-throughput

0.407

High

1344443

Q8SYG3
E2 ubiquitin-conjugating enzyme

1

9

High-throughput

0.407

High

1346062

Q8T4G5
AFG3 like matrix AAA peptidase subunit 2, isoform A

1

8

High-throughput

0.407

High

1467957

Q9VAH7
N-terminal kinase-like protein

1

6

High-throughput

0.407

High

1468069

Q9VAL7
Calnexin 99A, isoform A

1

5

High-throughput

0.407

High

1468128

CISD2
CDGSH iron-sulfur domain protein

1

4

High-throughput

0.407

High

1474964

IPO9
Importin-9

1

3

High-throughput

0.407

High

1476279

Q9VHL2
T-complex protein 1 subunit eta

1

1

High-throughput

0.407

High

1476788

Q9VJD1
Glucosidase 2 subunit beta

1

1

High-throughput

0.407

High

1476789

Q9VK46
Protein YIPF

1

5

High-throughput

0.407

High

1476790

Q9VK56
ABC-type glutathione-S-conjugate transporter

1

5

High-throughput

0.407

High

1476791

NFS1
Cysteine desulfurase, mitochondrial

1

2

High-throughput

0.407

High

1476793

Q9VKU1
long-chain-fatty-acid--CoA ligase

1

1

High-throughput

0.407

High

1476794

Q9VKZ8
Ubiquitin carboxyl-terminal hydrolase

1

3

High-throughput

0.407

High

1476805

Q9VQL7
Fatty acid synthase

1

1

High-throughput

0.407

High

1476809

Q9VS57
RE14391p

1

2

High-throughput

0.407

High

1476811

SRP68
Signal recognition particle subunit SRP68

1

1

High-throughput

0.407

High

1476812

FRL
Formin-like protein

1

5

High-throughput

0.407

High

1476814

Q9VV51
1-Acylglycerol-3-phosphate O-acyltransferase 3, isoform A

1

3

High-throughput

0.407

High

1476816

Q9VW54
26S proteasome non-ATPase regulatory subunit 2

1

1

High-throughput

0.407

High

1476818

IDH3A
Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

1

1

High-throughput

0.407

High

1476826

Q9W414
Regulatory particle triple-A ATPase 4

1

4

High-throughput

0.407

High

1476829

Q9Y162
vesicle-fusing ATPase

1

10

High-throughput

0.407

High

1378067

FLOWR
Calcium channel flower

2

0

High-throughput

0.310

High

1476828

Q9Y156
BcDNA.GH02976

2

0

High-throughput

0.310

High

357224

U184
UPF0184 protein CG14818

1

0

High-throughput

0.265

Low

1343153

Q8STG9
DSec61alpha

1

0

High-throughput

0.232

Low

1375215

Q94883
DNA replication-related element factor, isoform A

1

0

High-throughput

0.232

Low

1465128

API5
Apoptosis inhibitor 5 homolog

1

0

High-throughput

0.232

Low

1474171

ELP6
Elongator complex protein 6

1

0

High-throughput

0.232

Low

1476787

Q9VI57
Dephospho-CoA kinase domain-containing protein

1

0

High-throughput

0.232

Low

1476796

Q9VM57
Septin interacting protein 2, isoform A

1

0

High-throughput

0.232

Low

1476804

Q9VQI5
Interferon-related developmental regulator 1

1

0

High-throughput

0.232

Low

1476806

Q9VQX6
LP05054p

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025