Protein: CCNT1
Cyclin-T1 (CycT1) (Cyclin-T)

Gene: CCNT1
Organism: Homo sapiens
Interactions: 210
UniProt ID: O60563

Gene Ontology (top 5):
GO:0000079 - regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000976 - transcription cis-regulatory region binding
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

236725

CDK9
Cyclin-dependent kinase 9

54

20

Small-scale

0.997

High

236846

AFF4
AF4/FMR2 family member 4

7

2

Small-scale

0.967

High

236748

CDK6
Cyclin-dependent kinase 6

3

20

High-throughput

0.861

High

236727

AFF1
AF4/FMR2 family member 1

5

4

Small-scale

0.823

High

236671

HEXI1
Protein HEXIM1

18

4

Small-scale

0.767

High

236665

BRD4
Bromodomain-containing protein 4

12

15

Small-scale

0.758

High

236772

LARP7
La-related protein 7

8

6

Small-scale

0.749

High

236674

MYC
Myc proto-oncogene protein

6

7

Small-scale

0.730

High

236709

KPCI
Protein kinase C iota type

1

7

Small-scale

0.724

High

236716

KC1D
Casein kinase I isoform delta

1

4

High-throughput

0.691

High

236720

KC1E
Casein kinase I isoform epsilon

1

9

High-throughput

0.691

High

236723

CLK2
Dual specificity protein kinase CLK2

1

20

High-throughput

0.691

High

236724

CLK3
Dual specificity protein kinase CLK3

1

20

High-throughput

0.691

High

236759

PRP4K
Serine/threonine-protein kinase PRP4 homolog

1

20

High-throughput

0.691

High

236771

MK06
Mitogen-activated protein kinase 6

1

12

High-throughput

0.691

High

236811

DYRK2
Dual specificity tyrosine-phosphorylation-regulated kinase 2

1

20

High-throughput

0.691

High

236819

HEXI2
Protein HEXIM2

3

4

High-throughput

0.667

High

236833

ELL3
RNA polymerase II elongation factor ELL3

3

5

High-throughput

0.667

High

236675

ESR1
Estrogen receptor

3

19

Small-scale

0.660

High

236711

AF9
Protein AF-9

3

4

Small-scale

0.656

High

236786

MEPCE
7SK snRNA methylphosphate capping enzyme

3

1

High-throughput

0.656

High

236714

PI42A
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha

3

0

High-throughput

0.646

High

236718

CDK8
Cyclin-dependent kinase 8

1

20

Small-scale

0.646

High

236701

PML
Protein PML

2

9

Small-scale

0.634

High

236752

ENL
Protein ENL

2

8

Small-scale

0.628

High

236810

PSPC1
Paraspeckle component 1

2

3

High-throughput

0.628

High

236842

H2AW
Core histone macro-H2A.2

2

3

High-throughput

0.628

High

236691

CEBPB
CCAAT/enhancer-binding protein beta

2

4

Small-scale

0.624

High

236663

CCNT1
Cyclin-T1

1

7

Small-scale

0.621

High

236781

CTR9
RNA polymerase-associated protein CTR9 homolog

2

5

Small-scale

0.618

High

236664

CCNT2
Cyclin-T2

1

7

High-throughput

0.618

High

236669

CDK14
Cyclin-dependent kinase 14

1

20

High-throughput

0.618

High

236679

CDK1
Cyclin-dependent kinase 1

1

20

High-throughput

0.618

High

236695

CD11B
Cyclin-dependent kinase 11B

1

20

High-throughput

0.618

High

236764

CDK10
Cyclin-dependent kinase 10

1

20

High-throughput

0.618

High

236753

KMT2A
Histone-lysine N-methyltransferase 2A

2

6

Small-scale

0.611

High

123798

SPT5H
Transcription elongation factor SPT5

2

4

Small-scale

0.602

High

236775

BRDT
Bromodomain testis-specific protein

2

20

Small-scale

0.584

High

236797

SLX4
Structure-specific endonuclease subunit SLX4

2

3

High-throughput

0.584

High

236689

CATE
Cathepsin E

2

1

High-throughput

0.574

High

236706

AHR
Aryl hydrocarbon receptor

1

2

Small-scale

0.573

High

236843

MDFIC
MyoD family inhibitor domain-containing protein

1

1

Small-scale

0.573

High

236760

SNW1
SNW domain-containing protein 1

2

1

Small-scale

0.571

High

236847

NUFP1
FMR1-interacting protein NUFIP1

1

0

Small-scale

0.537

High

130129

ELL2
RNA polymerase II elongation factor ELL2

1

11

High-throughput

0.536

High

196920

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

1

4

High-throughput

0.536

High

204574

E41L2
Band 4.1-like protein 2

1

2

High-throughput

0.536

High

214797

CPSF5
Cleavage and polyadenylation specificity factor subunit 5

1

2

High-throughput

0.536

High

236666

PR40A
Pre-mRNA-processing factor 40 homolog A

1

7

High-throughput

0.536

High

236668

TOX4
TOX high mobility group box family member 4

1

7

High-throughput

0.536

High

236672

MED26
Mediator of RNA polymerase II transcription subunit 26

1

2

High-throughput

0.536

High

236683

RSSA
Small ribosomal subunit protein uS2

1

2

High-throughput

0.536

High

236698

TYY1
Transcriptional repressor protein YY1

1

1

High-throughput

0.536

High

236707

RS19
Small ribosomal subunit protein eS19

1

1

High-throughput

0.536

High

236712

KI67
Proliferation marker protein Ki-67

1

1

High-throughput

0.536

High

236715

SOX2
Transcription factor SOX-2

1

4

High-throughput

0.536

High

236726

MECP2
Methyl-CpG-binding protein 2

1

1

High-throughput

0.536

High

236730

MFAP1
Microfibrillar-associated protein 1

1

1

High-throughput

0.536

High

236734

RS16
Small ribosomal subunit protein uS9

1

1

High-throughput

0.536

High

236739

RL40
Ubiquitin-ribosomal protein eL40 fusion protein

1

5

High-throughput

0.536

High

236750

APBA1
Amyloid-beta A4 precursor protein-binding family A member 1

1

1

High-throughput

0.536

High

236755

CPSF1
Cleavage and polyadenylation specificity factor subunit 1

1

4

High-throughput

0.536

High

236761

SRC8
Src substrate cortactin

1

4

High-throughput

0.536

High

236766

SF3B4
Splicing factor 3B subunit 4

1

3

High-throughput

0.536

High

236770

CPSF6
Cleavage and polyadenylation specificity factor subunit 6

1

4

High-throughput

0.536

High

236779

CDC73
Parafibromin

1

1

Small-scale

0.536

High

236780

TAF2
Transcription initiation factor TFIID subunit 2

1

1

High-throughput

0.536

High

236784

WDR82
WD repeat-containing protein 82

1

8

High-throughput

0.536

High

236790

NUFP2
FMR1-interacting protein NUFIP2

1

1

High-throughput

0.536

High

236794

DDX42
ATP-dependent RNA helicase DDX42

1

3

High-throughput

0.536

High

236798

CPSF7
Cleavage and polyadenylation specificity factor subunit 7

1

4

High-throughput

0.536

High

236805

RB15B
Putative RNA-binding protein 15B

1

7

High-throughput

0.536

High

236808

PPIL4
Peptidyl-prolyl cis-trans isomerase-like 4

1

3

High-throughput

0.536

High

236809

ATX2L
Ataxin-2-like protein

1

2

High-throughput

0.536

High

236821

PP1RA
Serine/threonine-protein phosphatase 1 regulatory subunit 10

1

1

High-throughput

0.536

High

236829

NSRP1
Nuclear speckle splicing regulatory protein 1

1

1

High-throughput

0.536

High

236835

E41L5
Band 4.1-like protein 5

1

3

High-throughput

0.536

High

236836

DDX21
Nucleolar RNA helicase 2

1

4

High-throughput

0.536

High

236837

DCA13
DDB1- and CUL4-associated factor 13

1

1

High-throughput

0.536

High

236839

SLTM
SAFB-like transcription modulator

1

2

High-throughput

0.536

High

236840

DDX56
Probable ATP-dependent RNA helicase DDX56

1

6

High-throughput

0.536

High

236844

CPSF2
Cleavage and polyadenylation specificity factor subunit 2

1

1

High-throughput

0.536

High

236850

E41L3
Band 4.1-like protein 3

1

2

High-throughput

0.536

High

175797

P73
Tumor protein p73

1

9

Small-scale

0.515

High

236767

TAF7
Transcription initiation factor TFIID subunit 7

1

1

Small-scale

0.515

High

123144

CBX4
E3 SUMO-protein ligase CBX4

1

0

High-throughput

0.513

High

199621

SNUT1
U4/U6.U5 tri-snRNP-associated protein 1

1

0

High-throughput

0.513

High

236687

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.513

High

236722

RBM25
RNA-binding protein 25

1

0

High-throughput

0.513

High

236733

FGF12
Fibroblast growth factor 12

1

0

High-throughput

0.513

High

236740

IF5A1
Eukaryotic translation initiation factor 5A-1

1

0

High-throughput

0.513

High

236783

FIP1
Pre-mRNA 3'-end-processing factor FIP1

1

0

High-throughput

0.513

High

236804

FA98A
Protein FAM98A

1

0

High-throughput

0.513

High

236806

SNIP1
Smad nuclear-interacting protein 1

1

0

High-throughput

0.513

High

236822

POP1
Ribonucleases P/MRP protein subunit POP1

1

0

High-throughput

0.513

High

236824

TACO1
Translational activator of cytochrome c oxidase 1

1

0

High-throughput

0.513

High

236851

RCL1
RNA 3'-terminal phosphate cyclase-like protein

1

0

High-throughput

0.513

High

212083

HTSF1
17S U2 SnRNP complex component HTATSF1

1

4

Small-scale

0.501

High

236697

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

5

Small-scale

0.501

High

236704

T2FA
General transcription factor IIF subunit 1

1

1

Small-scale

0.501

High

236749

PURA
Transcriptional activator protein Pur-alpha

1

3

Small-scale

0.501

High

236754

EP300
Histone acetyltransferase p300

1

13

Small-scale

0.501

High

236773

GRAP1
GRIP1-associated protein 1

1

2

Small-scale

0.501

High

236815

KAT2B
Histone acetyltransferase KAT2B

1

15

Small-scale

0.501

High

236696

TCEA1
Transcription elongation factor A protein 1

1

4

Small-scale

0.500

High

236799

PAF1
RNA polymerase II-associated factor 1 homolog

1

1

Small-scale

0.500

High

236744

RT11
Small ribosomal subunit protein uS11m

1

4

High-throughput

0.489

High

236776

FA76B
Protein FAM76B

1

1

High-throughput

0.489

High

236817

ARRD3
Arrestin domain-containing protein 3

1

4

High-throughput

0.489

High

236825

MMTA2
Multiple myeloma tumor-associated protein 2

1

1

High-throughput

0.489

High

122394

MEN1
Menin

1

1

High-throughput

0.479

High

125032

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

5

High-throughput

0.479

High

134809

IMA3
Importin subunit alpha-3

1

2

High-throughput

0.479

High

199072

SIAH2
E3 ubiquitin-protein ligase SIAH2

1

2

Small-scale

0.479

High

200764

ARHG9
Rho guanine nucleotide exchange factor 9

1

3

High-throughput

0.479

High

202002

HNRPR
Heterogeneous nuclear ribonucleoprotein R

1

1

High-throughput

0.479

High

217413

AIRE
Autoimmune regulator

1

3

Small-scale

0.479

High

226001

PRKN
E3 ubiquitin-protein ligase parkin

1

8

High-throughput

0.479

High

236667

RECQ4
ATP-dependent DNA helicase Q4

1

4

High-throughput

0.479

High

236670

ARHGF
Rho guanine nucleotide exchange factor 15

1

1

High-throughput

0.479

High

236676

NTRK1
High affinity nerve growth factor receptor

1

3

High-throughput

0.479

High

236677

P53
Cellular tumor antigen p53

1

9

High-throughput

0.479

High

236678

HSPB1
Heat shock protein beta-1

1

4

High-throughput

0.479

High

236682

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

6

High-throughput

0.479

High

236684

ROA1
Heterogeneous nuclear ribonucleoprotein A1

1

5

High-throughput

0.479

High

236686

ANDR
Androgen receptor

1

19

High-throughput

0.479

High

236688

XRCC6
X-ray repair cross-complementing protein 6

1

3

High-throughput

0.479

High

236690

RFA2
Replication protein A 32 kDa subunit

1

8

High-throughput

0.479

High

236692

DDX5
Probable ATP-dependent RNA helicase DDX5

1

3

High-throughput

0.479

High

236699

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

8

High-throughput

0.479

High

236703

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.479

High

236705

FUS
RNA-binding protein FUS

1

5

High-throughput

0.479

High

236713

RS9
Small ribosomal subunit protein uS4

1

1

High-throughput

0.479

High

236717

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

9

High-throughput

0.479

High

236719

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

1

Small-scale

0.479

High

236721

CEBPA
CCAAT/enhancer-binding protein alpha

1

4

High-throughput

0.479

High

236728

TERF1
Telomeric repeat-binding factor 1

1

2

High-throughput

0.479

High

236731

ELL
RNA polymerase II elongation factor ELL

1

5

Small-scale

0.479

High

236732

MAX
Protein max

1

7

Small-scale

0.479

High

236735

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

3

High-throughput

0.479

High

236736

RS14
Small ribosomal subunit protein uS11

1

4

High-throughput

0.479

High

236737

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

236738

RS27A
Ubiquitin-ribosomal protein eS31 fusion protein

1

4

High-throughput

0.479

High

236741

ACTC
Actin, alpha cardiac muscle 1

1

2

High-throughput

0.479

High

236742

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.479

High

236743

RED1
Double-stranded RNA-specific editase 1

1

1

High-throughput

0.479

High

236746

H33
Histone H3.3

1

2

High-throughput

0.479

High

236751

RL6
Large ribosomal subunit protein eL6

1

1

High-throughput

0.479

High

236756

AKP13
A-kinase anchor protein 13

1

4

High-throughput

0.479

High

236757

TIAM1
Rho guanine nucleotide exchange factor TIAM1

1

5

High-throughput

0.479

High

236758

TIF1B
Transcription intermediary factor 1-beta

1

8

High-throughput

0.479

High

236765

PCBP1
Poly(rC)-binding protein 1

1

2

High-throughput

0.479

High

236768

TERF2
Telomeric repeat-binding factor 2

1

2

High-throughput

0.479

High

236769

NCOA2
Nuclear receptor coactivator 2

1

2

Small-scale

0.479

High

236774

RHG29
Rho GTPase-activating protein 29

1

2

High-throughput

0.479

High

236777

RHG21
Rho GTPase-activating protein 21

1

2

High-throughput

0.479

High

236778

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

1

3

Small-scale

0.479

High

236788

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

3

High-throughput

0.479

High

236789

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

2

High-throughput

0.479

High

236792

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

236795

SIAH1
E3 ubiquitin-protein ligase SIAH1

1

2

Small-scale

0.479

High

236796

SMC5
Structural maintenance of chromosomes protein 5

1

2

High-throughput

0.479

High

236807

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

2

High-throughput

0.479

High

236812

ESR2
Estrogen receptor beta

1

19

High-throughput

0.479

High

236813

REQU
Zinc finger protein ubi-d4

1

3

High-throughput

0.479

High

236814

RBP56
TATA-binding protein-associated factor 2N

1

3

High-throughput

0.479

High

236818

RNF31
E3 ubiquitin-protein ligase RNF31

1

8

High-throughput

0.479

High

236823

BARD1
BRCA1-associated RING domain protein 1

1

1

High-throughput

0.479

High

236827

DOCK9
Dedicator of cytokinesis protein 9

1

2

High-throughput

0.479

High

236828

NSD3
Histone-lysine N-methyltransferase NSD3

1

3

Small-scale

0.479

High

236845

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

236848

VAV3
Guanine nucleotide exchange factor VAV3

1

2

High-throughput

0.479

High

236680

NPM
Nucleophosmin

1

0

High-throughput

0.458

High

236681

PROF1
Profilin-1

1

0

Small-scale

0.458

High

236729

PMS1
PMS1 protein homolog 1

1

0

High-throughput

0.458

High

236745

RL24
Large ribosomal subunit protein eL24

1

0

High-throughput

0.458

High

236747

DAB2
Disabled homolog 2

1

0

Small-scale

0.458

High

236762

MVP
Major vault protein

1

0

High-throughput

0.458

High

236763

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

236782

RICTR
Rapamycin-insensitive companion of mTOR

1

0

High-throughput

0.458

High

236802

KDM1B
Lysine-specific histone demethylase 2

1

0

Small-scale

0.458

High

236803

SERB1
SERPINE1 mRNA-binding protein 1

1

0

High-throughput

0.458

High

236816

CLUA1
Clusterin-associated protein 1

1

0

High-throughput

0.458

High

236826

DDA1
DET1- and DDB1-associated protein 1

1

0

High-throughput

0.458

High

236831

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

236832

MET17
Ribosome assembly protein METTL17, mitochondrial

1

0

High-throughput

0.458

High

236841

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

236849

ASF1A
Histone chaperone ASF1A

1

0

High-throughput

0.458

High

236673

PTBP3
Polypyrimidine tract-binding protein 3

1

5

High-throughput

0.445

High

236710

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

1

High-throughput

0.445

High

236820

CEP63
Centrosomal protein of 63 kDa

1

1

High-throughput

0.445

High

236693

PEPC
Gastricsin

1

1

Small-scale

0.437

High

236785

TRI67
Tripartite motif-containing protein 67

1

8

High-throughput

0.437

High

236787

OTU6A
OTU domain-containing protein 6A

1

2

Small-scale

0.437

High

236830

PKHA4
Pleckstrin homology domain-containing family A member 4

1

5

High-throughput

0.437

High

236838

ATD3A
ATPase family AAA domain-containing protein 3A

1

2

High-throughput

0.437

High

236834

SENP2
Sentrin-specific protease 2

1

0

High-throughput

0.426

High

236791

T150A
Transmembrane protein 150A

3

0

High-throughput

0.347

High

236793

CMTD1
Catechol O-methyltransferase domain-containing protein 1

3

0

High-throughput

0.347

High

236852

CCG2
Voltage-dependent calcium channel gamma-2 subunit

3

0

High-throughput

0.347

High

236700

GRN
Progranulin

1

0

Small-scale

0.299

High

153849

NHRF1
Na(+)/H(+) exchange regulatory cofactor NHE-RF1

1

0

High-throughput

0.279

Low

236685

OST4
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 4

1

0

High-throughput

0.279

Low

236694

TNR1B
Tumor necrosis factor receptor superfamily member 1B

1

0

High-throughput

0.279

Low

236702

AMRP
Alpha-2-macroglobulin receptor-associated protein

1

0

High-throughput

0.279

Low

236708

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

0

High-throughput

0.279

Low

236800

ABTB2
Ankyrin repeat and BTB/POZ domain-containing protein 2

1

0

High-throughput

0.279

Low

196240

PJA2
E3 ubiquitin-protein ligase Praja-2

1

0

Small-scale

0.249

Low

236801

KDF1
Keratinocyte differentiation factor 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024