Protein: SMN
Survival motor neuron protein

Gene: SMN
Organism: Drosophila melanogaster
Interactions: 90
UniProt ID: Q9VV74

Gene Ontology (top 5):
GO:0000387 - spliceosomal snRNP assembly
GO:0000398 - mRNA splicing, via spliceosome
GO:0002164 - larval development
GO:0003723 - RNA binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1487119

GEMI2
Gem-associated protein 2

9

2

Small-scale

0.964

High

1487118

SMN
Survival motor neuron protein

7

5

Small-scale

0.956

High

1463263

Q9V3C4
RNA helicase

8

5

Small-scale

0.743

High

1487132

GEM4A
Gem-associated protein 4a

4

1

Small-scale

0.672

High

1179058

POP7
Ribonuclease P protein subunit p20

1

1

Small-scale

0.586

High

1465934

RU2A
Probable U2 small nuclear ribonucleoprotein A'

2

4

High-throughput

0.571

High

57266

ICLN
Methylosome subunit pICln

2

1

Small-scale

0.552

High

1470145

SYFB
Phenylalanine--tRNA ligase beta subunit

2

0

High-throughput

0.547

High

612417

ACTN
Alpha-actinin, sarcomeric

1

0

Small-scale

0.537

High

874088

RAC2
Ras-related protein Rac2

1

2

High-throughput

0.508

High

1306445

INDRA
Zinc finger protein indra

1

0

High-throughput

0.486

High

1471387

Q9VDA2
Ladybird late, isoform A

1

0

High-throughput

0.486

High

1477221

TUTT
Terminal uridylyltransferase Tailor

1

0

High-throughput

0.486

High

84788

SPN1
Snurportin-1

1

1

Small-scale

0.479

High

232192

SMD3
Small nuclear ribonucleoprotein Sm D3

1

10

Small-scale

0.479

High

1052594

RSMB
Small nuclear ribonucleoprotein-associated protein B

1

5

Small-scale

0.479

High

1173433

CUL1
Cullin homolog 1

1

2

Small-scale

0.479

High

1305094

NAA38
N-alpha-acetyltransferase 38, NatC auxiliary subunit

1

10

Small-scale

0.479

High

1306719

GEM4B
Gem-associated protein 4b

1

1

Small-scale

0.479

High

1471475

Q9VDE3
LD08669p

1

2

Small-scale

0.479

High

1485516

Q9VSD6
D-Importin 7/RanBP7

1

1

Small-scale

0.479

High

1468606

Q9VAX8
116 kDa U5 small nuclear ribonucleoprotein component

1

0

High-throughput

0.460

High

305536

O77430
GEO01111p1

1

0

Small-scale

0.458

High

1472426

Q9VEA4
Trimethylguanosine synthase

1

0

Small-scale

0.458

High

1487130

SYFA
Phenylalanine--tRNA ligase alpha subunit

1

0

High-throughput

0.458

High

56897

A1ZAK3
Protein DEK

1

1

High-throughput

0.445

High

534503

ACT1
Actin-5C

1

1

High-throughput

0.445

High

847930

SNRPA
U1 small nuclear ribonucleoprotein A

1

7

High-throughput

0.445

High

887819

MCM2
DNA replication licensing factor Mcm2

1

1

High-throughput

0.445

High

1173253

RUXF
Small nuclear ribonucleoprotein F

1

9

High-throughput

0.445

High

1177499

Q29QQ9
Ribosomal RNA-processing protein 42

1

1

High-throughput

0.445

High

1465540

MCM6
DNA replication licensing factor Mcm6

1

1

High-throughput

0.445

High

1476589

Q9VHR5
Veneno

1

1

High-throughput

0.445

High

1476729

Q9VHT5
Large ribosomal subunit protein uL1m

1

1

High-throughput

0.445

High

1477030

SMD2
Probable small nuclear ribonucleoprotein Sm D2

1

1

High-throughput

0.445

High

1479980

Q9VKW8
U6 snRNA-associated Sm-like protein LSm4

1

10

High-throughput

0.445

High

1487120

RUXG
Probable small nuclear ribonucleoprotein G

1

13

High-throughput

0.445

High

1487129

Q9W224
Novel spermatogenesis regulator, isoform A

1

3

High-throughput

0.445

High

1487133

DDB1
DNA damage-binding protein 1

1

1

High-throughput

0.445

High

1487134

SYQ
Probable glutamine--tRNA ligase

1

2

High-throughput

0.445

High

1487135

Q9Y134
RNA helicase

1

7

High-throughput

0.445

High

1474615

Q9VGE4
FI04457p

1

1

Small-scale

0.437

High

567602

GPDA
Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic

1

0

High-throughput

0.426

High

614629

MLR
Myosin regulatory light chain 2

1

0

High-throughput

0.426

High

771374

MYSP2
Paramyosin, short form

1

0

High-throughput

0.426

High

868894

TNNC1
Troponin C, isoform 1

1

0

High-throughput

0.426

High

875561

PTPS
6-pyruvoyl tetrahydrobiopterin synthase

1

0

High-throughput

0.426

High

929079

DOD
Putative peptidyl-prolyl cis-trans isomerase dodo

1

0

High-throughput

0.426

High

1440203

NASP
Nuclear autoantigenic sperm protein homolog

1

0

High-throughput

0.426

High

1466185

SYF2
Pre-mRNA-splicing factor Syf2

1

0

High-throughput

0.426

High

1466666

SRRT
Serrate RNA effector molecule homolog

1

0

High-throughput

0.426

High

1470100

Q9VC93
Exosome complex exonuclease RRP44

1

0

High-throughput

0.426

High

1475387

Q9VGZ2
FI06805p

1

0

High-throughput

0.426

High

1483348

Q9VPM0
GH06023p

1

0

High-throughput

0.426

High

1485527

DBR1
Lariat debranching enzyme

1

0

High-throughput

0.426

High

1487124

UBA5
Ubiquitin-like modifier-activating enzyme 5

1

0

High-throughput

0.426

High

1487125

THUM1
THUMP domain-containing protein 1 homolog

1

0

High-throughput

0.426

High

1487128

Q9W1M9
Exosome complex component RRP4

1

0

High-throughput

0.426

High

1487131

Q9W4J4
GM14292p

1

0

High-throughput

0.426

High

620822

TNNT
Troponin T, skeletal muscle

1

1

High-throughput

0.407

High

1264311

Q7K0L8
FLICE-associated huge protein, isoform A

1

1

High-throughput

0.407

High

1345971

Q8T4A9
Exosome complex component RRP45

1

1

High-throughput

0.407

High

1483314

RM10
Large ribosomal subunit protein uL10m

1

1

High-throughput

0.407

High

1487122

Q9VYT3
FI23714p1

1

1

High-throughput

0.407

High

1487127

Q9W108
FI01540p

1

5

High-throughput

0.407

High

1046688

MTDC
Bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial

2

0

High-throughput

0.305

High

1467807

Q9VAC7
MIP04834p

1

0

High-throughput

0.265

Low

1478408

Q9VJD8
AT13217p1

1

0

High-throughput

0.265

Low

1305083

Q8IPY8
IP07509p

1

0

High-throughput

0.257

Low

53238

A1Z7L0
FI16617p1

1

0

High-throughput

0.251

Low

1484064

Q9VQ96
RH13166p

1

0

High-throughput

0.251

Low

1264848

Q7K1C3
Enoyl-CoA hydratase domain-containing protein 3, mitochondrial

1

0

High-throughput

0.249

Low

1474281

Q9VG23
GH22994p

1

0

High-throughput

0.249

Low

1487123

COMDA
COMM domain-containing protein 10 homolog Vlet

1

0

Small-scale

0.249

Low

482804

TPM2
Tropomyosin-2

1

0

High-throughput

0.232

Low

782901

TNNI
Troponin I

1

0

High-throughput

0.232

Low

1264938

Q7K1Q7
Ribosome assembly factor mrt4

1

0

High-throughput

0.232

Low

1301064

Q8I062
GH23305p

1

0

High-throughput

0.232

Low

1344579

Q8SYM9
FI04119p

1

0

High-throughput

0.232

Low

1473088

Q9VEP6
Adenylosuccinate lyase

1

0

High-throughput

0.232

Low

1477699

NESD
Protein nessun dorma

1

0

High-throughput

0.232

Low

1481391

Q9VM14
dihydrolipoyllysine-residue acetyltransferase

1

0

High-throughput

0.232

Low

1481423

Q9VM18
Trehalose 6-phosphate phosphatase

1

0

High-throughput

0.232

Low

1482966

Q9VNZ3
DNA-directed RNA polymerases I, II, and III subunit RPABC3

1

0

High-throughput

0.232

Low

1483551

Q9VPS0
GEO10683p1

1

0

High-throughput

0.232

Low

1485867

QTRT2
Queuine tRNA-ribosyltransferase accessory subunit 2

1

0

High-throughput

0.232

Low

1486742

RM39
Large ribosomal subunit protein mL39

1

0

High-throughput

0.232

Low

1487121

SUN
Protein stunted

1

0

High-throughput

0.232

Low

1487126

SAHH2
Adenosylhomocysteinase-like 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025