Protein: GRP3
Ras guanyl-releasing protein 3 (Calcium and DAG-regulated guanine nucleotide exchange factor III) (Guanine nucleotide exchange factor for Rap1)

Gene: GRP3, RASGRP3
Organism: Homo sapiens
Interactions: 17
UniProt ID: Q8IV61

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005096 - GTPase activator activity
GO:0005509 - calcium ion binding
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

408644

KPCB
Protein kinase C beta type

2

8

Small-scale

0.778

High

1217320

DYL2
Dynein light chain 2, cytoplasmic

1

1

High-throughput

0.740

High

984512

KPCD
Protein kinase C delta type

1

8

Small-scale

0.724

High

647081

1433T
14-3-3 protein theta

1

20

High-throughput

0.665

High

568728

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

1

7

Small-scale

0.647

High

969095

KPCE
Protein kinase C epsilon type

1

8

Small-scale

0.647

High

981056

KPCT
Protein kinase C theta type

1

8

Small-scale

0.647

High

277591

DGKI
Diacylglycerol kinase iota

1

5

Small-scale

0.618

High

349455

RASH
GTPase HRas

1

20

Small-scale

0.618

High

395116

A4
Amyloid-beta precursor protein

1

7

High-throughput

0.501

High

787265

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

2

Small-scale

0.501

High

126300

ST1C2
Sulfotransferase 1C2

1

1

High-throughput

0.494

High

175693

TRI18
E3 ubiquitin-protein ligase Midline-1

1

3

Small-scale

0.437

High

123388

GET1
Guided entry of tail-anchored proteins factor 1

2

0

High-throughput

0.316

High

1217319

DHB11
Estradiol 17-beta-dehydrogenase 11

2

0

High-throughput

0.316

High

896777

ARP3
Actin-related protein 3

1

0

Small-scale

0.249

Low

1217321

ZDH15
Palmitoyltransferase ZDHHC15

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024