Protein: WAC
WW domain-containing adapter protein with coiled-coil

Gene: WAC
Organism: Homo sapiens
Interactions: 78
UniProt ID: Q9BTA9

Gene Ontology (top 5):
GO:0000993 - RNA polymerase II complex binding
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005681 - spliceosomal complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

256334

BRE1B
E3 ubiquitin-protein ligase BRE1B

4

5

Small-scale

0.708

High

1138213

BRE1A
E3 ubiquitin-protein ligase BRE1A

4

5

Small-scale

0.703

High

1311979

WAC
WW domain-containing adapter protein with coiled-coil

1

6

High-throughput

0.698

High

580091

K1C15
Keratin, type I cytoskeletal 15

4

0

High-throughput

0.671

High

387415

P53
Cellular tumor antigen p53

3

6

Small-scale

0.640

High

1081248

NF2L2
Nuclear factor erythroid 2-related factor 2

2

6

High-throughput

0.628

High

1127146

MTUS2
Microtubule-associated tumor suppressor candidate 2

2

2

High-throughput

0.628

High

1295185

VCIP1
Deubiquitinating protein VCPIP1

2

0

Small-scale

0.603

High

791927

HD
Huntingtin

2

3

High-throughput

0.596

High

861915

PLK1
Serine/threonine-protein kinase PLK1

1

3

Small-scale

0.578

High

160747

AURKA
Aurora kinase A

1

2

Small-scale

0.561

High

415047

CDK1
Cyclin-dependent kinase 1

1

2

Small-scale

0.561

High

625016

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

1

Small-scale

0.561

High

157234

BACH1
Transcription regulator protein BACH1

1

4

High-throughput

0.541

High

865079

TTC3
E3 ubiquitin-protein ligase TTC3

1

8

High-throughput

0.541

High

1255307

MIPT3
TRAF3-interacting protein 1

2

1

High-throughput

0.539

High

875270

TERA
Transitional endoplasmic reticulum ATPase

1

0

Small-scale

0.537

High

639064

S100P
Protein S100-P

1

1

High-throughput

0.536

High

1311982

RBM12
RNA-binding protein 12

1

3

High-throughput

0.536

High

1160000

KLC3
Kinesin light chain 3

1

3

High-throughput

0.523

High

1307558

AKAP9
A-kinase anchor protein 9

1

4

High-throughput

0.523

High

1311988

T3JAM
TRAF3-interacting JNK-activating modulator

1

4

High-throughput

0.523

High

1216546

ZDH17
Palmitoyltransferase ZDHHC17

1

1

High-throughput

0.518

High

1311981

UBQL4
Ubiquilin-4

1

3

High-throughput

0.508

High

476294

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

4

Small-scale

0.501

High

281053

KRT38
Keratin, type I cuticular Ha8

1

1

High-throughput

0.489

High

434427

TPM2
Tropomyosin beta chain

1

2

High-throughput

0.489

High

556662

CBR1
Carbonyl reductase [NADPH] 1

1

1

High-throughput

0.489

High

661414

S10A2
Protein S100-A2

1

1

High-throughput

0.489

High

1293689

C2AIL
CDKN2AIP N-terminal-like protein

1

1

High-throughput

0.489

High

802894

CRKL
Crk-like protein

1

7

High-throughput

0.481

High

1311984

HM20B
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-related

1

7

High-throughput

0.481

High

124068

SPT5H
Transcription elongation factor SPT5

1

8

High-throughput

0.479

High

487725

ANDR
Androgen receptor

1

15

High-throughput

0.479

High

523975

XRCC6
X-ray repair cross-complementing protein 6

1

2

High-throughput

0.479

High

553581

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.479

High

652106

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

721302

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.479

High

829056

UBE2A
Ubiquitin-conjugating enzyme E2 A

1

1

Small-scale

0.479

High

831649

CEBPA
CCAAT/enhancer-binding protein alpha

1

5

High-throughput

0.479

High

853970

NCBP2
Nuclear cap-binding protein subunit 2

1

1

High-throughput

0.479

High

917842

H4
Histone H4

1

4

High-throughput

0.479

High

927772

UBE2B
Ubiquitin-conjugating enzyme E2 B

1

1

Small-scale

0.479

High

941372

RNF4
E3 ubiquitin-protein ligase RNF4

1

2

High-throughput

0.479

High

967400

EWS
RNA-binding protein EWS

1

4

High-throughput

0.479

High

980860

TLE3
Transducin-like enhancer protein 3

1

4

High-throughput

0.479

High

1027227

CBX3
Chromobox protein homolog 3

1

5

High-throughput

0.479

High

1200626

NAA40
N-alpha-acetyltransferase 40

1

2

High-throughput

0.479

High

1221691

SMC5
Structural maintenance of chromosomes protein 5

1

3

High-throughput

0.479

High

1236471

SIR6
NAD-dependent protein deacylase sirtuin-6

1

4

Small-scale

0.479

High

1239161

ZBT38
Zinc finger and BTB domain-containing protein 38

1

1

Small-scale

0.479

High

1288275

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

3

High-throughput

0.479

High

1311987

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

1059262

GOGB1
Golgin subfamily B member 1

1

1

High-throughput

0.470

High

1311986

TFP11
Tuftelin-interacting protein 11

1

0

High-throughput

0.460

High

538601

CCNB1
G2/mitotic-specific cyclin-B1

1

0

Small-scale

0.458

High

1055466

DHX8
ATP-dependent RNA helicase DHX8

1

0

High-throughput

0.458

High

1148762

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

395623

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.457

High

1081138

CCDC6
Coiled-coil domain-containing protein 6

1

7

High-throughput

0.439

High

1144611

TENS2
Tensin-2

1

5

High-throughput

0.439

High

1252441

LNX1
E3 ubiquitin-protein ligase LNX

1

4

Small-scale

0.439

High

1311983

NDE1
Nuclear distribution protein nudE homolog 1

1

3

High-throughput

0.439

High

517436

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.438

High

297672

RHBT1
Rho-related BTB domain-containing protein 1

1

11

High-throughput

0.437

High

932356

ACTC
Actin, alpha cardiac muscle 1

1

6

High-throughput

0.437

High

1311980

RHBT2
Rho-related BTB domain-containing protein 2

1

11

High-throughput

0.437

High

1296678

C170L
Cep170-like protein

1

1

High-throughput

0.407

High

1262312

DYDC1
DPY30 domain-containing protein 1

2

0

High-throughput

0.330

High

1023784

TRAF1
TNF receptor-associated factor 1

1

0

High-throughput

0.299

High

1255515

SYTL5
Synaptotagmin-like protein 5

1

0

High-throughput

0.299

High

1311985

SLAI2
SLAIN motif-containing protein 2

1

0

High-throughput

0.279

Low

1046396

MOBP
Myelin-associated oligodendrocyte basic protein

1

0

High-throughput

0.251

Low

1082951

CDC37
Hsp90 co-chaperone Cdc37

1

0

High-throughput

0.251

Low

1268003

EDEM1
ER degradation-enhancing alpha-mannosidase-like protein 1

1

0

High-throughput

0.249

Low

886422

NAL12
NACHT, LRR and PYD domains-containing protein 12

1

0

Small-scale

0.238

Low

1270192

HTRA1
Serine protease HTRA1

1

0

Small-scale

0.238

Low


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Last updated: 15 Jul 2024