Protein: CPNS1
Calpain small subunit 1 (CSS1) (Calcium-activated neutral proteinase small subunit) (CANP small subunit) (Calcium-dependent protease small subunit) (CDPS) (Calcium-dependent protease small subunit 1) (Calpain regulatory subunit)

Gene: CPNS1, CAPNS1
Organism: Homo sapiens
Interactions: 80
UniProt ID: P04632

Gene Ontology (top 5):
GO:0004198 - calcium-dependent cysteine-type endopeptidase activity
GO:0005509 - calcium ion binding
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006508 - proteolysis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

385827

CAN1
Calpain-1 catalytic subunit

5

15

Small-scale

0.724

High

385837

CAN2
Calpain-2 catalytic subunit

4

15

Small-scale

0.686

High

385882

CPNS2
Calpain small subunit 2

3

17

High-throughput

0.667

High

385833

CFTR
Cystic fibrosis transmembrane conductance regulator

3

6

High-throughput

0.643

High

352433

TNFA
Tumor necrosis factor

3

0

High-throughput

0.638

High

385849

CCNF
Cyclin-F

2

6

High-throughput

0.584

High

385838

VCAM1
Vascular cell adhesion protein 1

2

5

High-throughput

0.571

High

385843

SHC1
SHC-transforming protein 1

2

3

High-throughput

0.571

High

385862

GRB2
Growth factor receptor-bound protein 2

2

1

High-throughput

0.571

High

385883

KCTD7
BTB/POZ domain-containing protein KCTD7

1

5

Small-scale

0.561

High

385872

ATRAP
Type-1 angiotensin II receptor-associated protein

1

0

High-throughput

0.549

High

129525

TRAF5
TNF receptor-associated factor 5

1

3

High-throughput

0.541

High

385831

CDK4
Cyclin-dependent kinase 4

1

8

High-throughput

0.541

High

385856

PAR2
Proteinase-activated receptor 2

1

4

High-throughput

0.541

High

385860

RAB1A
Ras-related protein Rab-1A

1

2

High-throughput

0.541

High

385842

MAP4
Microtubule-associated protein 4

1

11

High-throughput

0.536

High

385861

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

0

High-throughput

0.518

High

385875

GET4
Golgi to ER traffic protein 4 homolog

1

0

High-throughput

0.518

High

385894

DRG1
Developmentally-regulated GTP-binding protein 1

1

0

High-throughput

0.518

High

385840

RASA1
Ras GTPase-activating protein 1

1

13

Small-scale

0.515

High

385839

FILA
Filaggrin

1

3

Small-scale

0.501

High

385858

CDC42
Cell division control protein 42 homolog

1

8

High-throughput

0.501

High

385847

ARRC
Arrestin-C

1

1

High-throughput

0.494

High

385854

TERF1
Telomeric repeat-binding factor 1

1

1

High-throughput

0.494

High

385884

CF418
Cilia- and flagella-associated protein 418

1

0

High-throughput

0.493

High

385870

SPXN4
Sperm protein associated with the nucleus on the X chromosome N4

1

1

High-throughput

0.489

High

385845

IL2RG
Cytokine receptor common subunit gamma

1

3

Small-scale

0.481

High

385848

STAT3
Signal transducer and activator of transcription 3

1

3

High-throughput

0.481

High

125078

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

7

High-throughput

0.479

High

226237

PRKN
E3 ubiquitin-protein ligase parkin

1

12

High-throughput

0.479

High

296259

UBP1
Ubiquitin carboxyl-terminal hydrolase 1

1

3

Small-scale

0.479

High

345167

KNG1
Kininogen-1

1

1

High-throughput

0.479

High

362669

FINC
Fibronectin

1

5

High-throughput

0.479

High

368798

ESR1
Estrogen receptor

1

6

High-throughput

0.479

High

373495

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

5

High-throughput

0.479

High

385830

BIP
Endoplasmic reticulum chaperone BiP

1

4

High-throughput

0.479

High

385834

ITA4
Integrin alpha-4

1

5

High-throughput

0.479

High

385836

IL7RA
Interleukin-7 receptor subunit alpha

1

1

High-throughput

0.479

High

385851

FNTB
Protein farnesyltransferase subunit beta

1

3

High-throughput

0.479

High

385852

CDK7
Cyclin-dependent kinase 7

1

8

High-throughput

0.479

High

385853

RAB7A
Ras-related protein Rab-7a

1

5

High-throughput

0.479

High

385855

TERA
Transitional endoplasmic reticulum ATPase

1

3

High-throughput

0.479

High

385859

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

4

High-throughput

0.479

High

385866

CDC20
Cell division cycle protein 20 homolog

1

2

High-throughput

0.479

High

385867

CUL3
Cullin-3

1

8

Small-scale

0.479

High

385868

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

3

High-throughput

0.479

High

385869

CL16A
Protein CLEC16A

1

1

High-throughput

0.479

High

385876

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

7

High-throughput

0.479

High

385881

GCP3
Gamma-tubulin complex component 3

1

1

High-throughput

0.479

High

385885

GCP2
Gamma-tubulin complex component 2

1

1

High-throughput

0.479

High

385887

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

7

Small-scale

0.479

High

385889

ANLN
Anillin

1

4

High-throughput

0.479

High

385892

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

385893

RUVB1
RuvB-like 1

1

1

High-throughput

0.479

High

385891

PRGC1
Peroxisome proliferator-activated receptor gamma coactivator 1-alpha

1

0

High-throughput

0.460

High

385828

ADRB2
Beta-2 adrenergic receptor

1

0

High-throughput

0.458

High

385844

PURA2
Adenylosuccinate synthetase isozyme 2

1

0

High-throughput

0.458

High

385877

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.458

High

385879

NEDD1
Protein NEDD1

1

0

High-throughput

0.458

High

385865

FMR1
Fragile X messenger ribonucleoprotein 1

1

1

High-throughput

0.457

High

385829

TAU
Microtubule-associated protein tau

1

16

High-throughput

0.445

High

385832

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.438

High

214025

SPOP
Speckle-type POZ protein

1

6

High-throughput

0.437

High

329223

AGR2
Anterior gradient protein 2 homolog

1

1

High-throughput

0.437

High

385835

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.437

High

385841

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.437

High

385846

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.437

High

385850

MAGA3
Melanoma-associated antigen 3

1

4

Small-scale

0.437

High

385873

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.437

High

385880

DUS19
Dual specificity protein phosphatase 19

1

5

High-throughput

0.437

High

385890

PIHD1
PIH1 domain-containing protein 1

1

2

High-throughput

0.437

High

385895

AAR2
Protein AAR2 homolog

1

2

High-throughput

0.437

High

385886

LRCC1
Leucine-rich repeat and coiled-coil domain-containing protein 1

1

7

High-throughput

0.417

High

385864

XIAP
E3 ubiquitin-protein ligase XIAP

1

3

Small-scale

0.388

High

385857

ATPK
ATP synthase subunit f, mitochondrial

1

0

High-throughput

0.282

High

385878

SMYD1
Histone-lysine N-methyltransferase SMYD1

1

0

High-throughput

0.279

Low

385863

SARNP
SAP domain-containing ribonucleoprotein

1

0

High-throughput

0.249

Low

385871

TET5C
Terminal nucleotidyltransferase 5C

1

0

High-throughput

0.249

Low

385874

MEPCE
7SK snRNA methylphosphate capping enzyme

1

0

High-throughput

0.249

Low

385888

SIL1
Nucleotide exchange factor SIL1

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024