Protein: SCNNA
Amiloride-sensitive sodium channel subunit alpha (Alpha-NaCH) (Epithelial Na(+) channel subunit alpha) (Alpha-ENaC) (ENaCA) (Nonvoltage-gated sodium channel 1 subunit alpha) (SCNEA)

Gene: SCNNA, SCNN1A
Organism: Homo sapiens
Interactions: 65
UniProt ID: P37088

Gene Ontology (top 5):
GO:0001669 - acrosomal vesicle
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0005886 - plasma membrane
GO:0006883 - intracellular sodium ion homeostasis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

739583

SCNNB
Amiloride-sensitive sodium channel subunit beta

3

14

Small-scale

0.854

High

739584

SCNNG
Amiloride-sensitive sodium channel subunit gamma

3

14

Small-scale

0.827

High

739582

NEDD4
E3 ubiquitin-protein ligase NEDD4

7

20

Small-scale

0.752

High

739604

NED4L
E3 ubiquitin-protein ligase NEDD4-like

10

20

Small-scale

0.747

High

739602

ASIC4
Acid-sensing ion channel 4

1

13

High-throughput

0.691

High

158911

NCTR3
Natural cytotoxicity triggering receptor 3

1

0

High-throughput

0.656

High

739616

BTNL2
Butyrophilin-like protein 2

1

0

High-throughput

0.656

High

739585

SCNND
Amiloride-sensitive sodium channel subunit delta

1

14

Small-scale

0.618

High

271044

UBP2
Ubiquitin carboxyl-terminal hydrolase 2

2

6

Small-scale

0.584

High

739621

EPN1
Epsin-1

1

2

Small-scale

0.561

High

739580

SCNNA
Amiloride-sensitive sodium channel subunit alpha

1

13

Small-scale

0.552

High

354680

DRA
HLA class II histocompatibility antigen, DR alpha chain

1

12

High-throughput

0.536

High

354818

DQA1
HLA class II histocompatibility antigen, DQ alpha 1 chain

1

14

High-throughput

0.536

High

362130

ACHA
Acetylcholine receptor subunit alpha

1

1

High-throughput

0.536

High

382585

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

1

14

High-throughput

0.536

High

410551

CD1A
T-cell surface glycoprotein CD1a

1

10

High-throughput

0.536

High

540277

GPIX
Platelet glycoprotein IX

1

1

High-throughput

0.536

High

557054

PGFRA
Platelet-derived growth factor receptor alpha

1

1

High-throughput

0.536

High

570308

HLAG
HLA class I histocompatibility antigen, alpha chain G

1

8

High-throughput

0.536

High

739590

ACHD
Acetylcholine receptor subunit delta

1

1

High-throughput

0.536

High

739592

PON2
Serum paraoxonase/arylesterase 2

1

5

High-throughput

0.536

High

739595

LRAD1
Low-density lipoprotein receptor class A domain-containing protein 1

1

1

High-throughput

0.536

High

739599

CLC4C
C-type lectin domain family 4 member C

1

3

High-throughput

0.536

High

739601

T106A
Transmembrane protein 106A

1

2

High-throughput

0.536

High

739609

CST11
Cystatin-11

1

1

High-throughput

0.536

High

739614

DNJB9
DnaJ homolog subfamily B member 9

1

2

High-throughput

0.536

High

739615

CLC2D
C-type lectin domain family 2 member D

1

3

High-throughput

0.536

High

739617

ADA30
Disintegrin and metalloproteinase domain-containing protein 30

1

1

High-throughput

0.536

High

739618

CLC4E
C-type lectin domain family 4 member E

1

3

High-throughput

0.536

High

318357

ECEL1
Endothelin-converting enzyme-like 1

1

0

High-throughput

0.513

High

430688

CD3E
T-cell surface glycoprotein CD3 epsilon chain

1

0

High-throughput

0.513

High

519404

FCERA
High affinity immunoglobulin epsilon receptor subunit alpha

1

0

High-throughput

0.513

High

585601

FUT1
Galactoside alpha-(1,2)-fucosyltransferase 1

1

0

High-throughput

0.513

High

739586

SLUR1
Secreted Ly-6/uPAR-related protein 1

1

0

High-throughput

0.513

High

739589

NRG1
Pro-neuregulin-1, membrane-bound isoform

1

0

High-throughput

0.513

High

739598

SIGL1
SIGLEC family-like protein 1

1

0

High-throughput

0.513

High

739600

GGH
Gamma-glutamyl hydrolase

1

0

High-throughput

0.513

High

739613

ITM2C
Integral membrane protein 2C

1

0

High-throughput

0.513

High

125197

WWP2
NEDD4-like E3 ubiquitin-protein ligase WWP2

1

20

Small-scale

0.501

High

739596

HECW1
E3 ubiquitin-protein ligase HECW1

1

20

Small-scale

0.501

High

739603

ITCH
E3 ubiquitin-protein ligase Itchy homolog

1

20

Small-scale

0.501

High

739620

COMDA
COMM domain-containing protein 10

1

4

Small-scale

0.501

High

314468

APOM
Apolipoprotein M

1

1

High-throughput

0.489

High

514350

PSPC
Surfactant protein C

1

1

High-throughput

0.489

High

739605

TSN18
Tetraspanin-18

1

1

High-throughput

0.489

High

739610

CST9L
Cystatin-9-like

1

1

High-throughput

0.489

High

739612

SDF2L
Stromal cell-derived factor 2-like protein 1

1

3

High-throughput

0.489

High

739606

TS101
Tumor susceptibility gene 101 protein

1

1

Small-scale

0.481

High

739608

WWP1
NEDD4-like E3 ubiquitin-protein ligase WWP1

1

20

Small-scale

0.481

High

739623

SERP1
Stress-associated endoplasmic reticulum protein 1

1

2

Small-scale

0.481

High

739588

CSK21
Casein kinase II subunit alpha

1

0

Small-scale

0.480

High

159916

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

1

Small-scale

0.479

High

739581

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

6

Small-scale

0.479

High

739591

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

6

Small-scale

0.479

High

739593

STX1A
Syntaxin-1A

1

3

Small-scale

0.479

High

739597

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

20

Small-scale

0.479

High

739619

HYOU1
Hypoxia up-regulated protein 1

1

1

Small-scale

0.479

High

739622

AP1M2
AP-1 complex subunit mu-2

1

2

Small-scale

0.479

High

739587

UBC9
SUMO-conjugating enzyme UBC9

1

0

Small-scale

0.460

High

234913

SNX3
Sorting nexin-3

1

0

Small-scale

0.458

High

354933

DRB1
HLA class II histocompatibility antigen, DRB1 beta chain

1

12

High-throughput

0.445

High

739607

DERL1
Derlin-1

1

1

Small-scale

0.437

High

739594

TAZ
Tafazzin

1

0

High-throughput

0.279

Low

739611

UD17
UDP-glucuronosyltransferase 1A7

1

0

High-throughput

0.279

Low


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Last updated: 15 Jul 2024