Protein: FBN2
Fibrillin-2 [Cleaved into: Placensin]

Gene: FBN2
Organism: Homo sapiens
Interactions: 65
UniProt ID: P35556

Gene Ontology (top 5):
GO:0001527 - microfibril
GO:0005179 - hormone activity
GO:0005201 - extracellular matrix structural constituent
GO:0005509 - calcium ion binding
GO:0005576 - extracellular region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

724331

FBN1
Fibrillin-1 [Cleaved into: Asprosin]

2

19

Small-scale

0.768

High

724370

LTBP1
Latent-transforming growth factor beta-binding protein 1

1

17

Small-scale

0.724

High

371464

KLKB1
Plasma kallikrein

1

11

High-throughput

0.691

High

724367

NOTC2
Neurogenic locus notch homolog protein 2

1

19

High-throughput

0.691

High

724371

LTBP2
Latent-transforming growth factor beta-binding protein 2

1

17

High-throughput

0.691

High

724373

FX4L6
Forkhead box protein D4-like 6

3

8

High-throughput

0.667

High

126359

MATN2
Matrilin-2

1

18

Small-scale

0.647

High

362882

FINC
Fibronectin

1

10

Small-scale

0.647

High

724361

FBN2
Fibrillin-2 [Cleaved into: Placensin]

1

17

Small-scale

0.647

High

724376

LYPD4
Ly6/PLAUR domain-containing protein 4

2

1

High-throughput

0.628

High

724382

ATL1
ADAMTS-like protein 1

2

11

High-throughput

0.628

High

724386

VWCE
von Willebrand factor C and EGF domain-containing protein

2

19

High-throughput

0.628

High

724401

PRG3
Proteoglycan 3

2

15

High-throughput

0.628

High

434623

TSP1
Thrombospondin-1

1

17

Small-scale

0.621

High

724402

ST14
Suppressor of tumorigenicity 14 protein

1

11

High-throughput

0.618

High

532904

PRG2
Bone marrow proteoglycan

2

15

High-throughput

0.611

High

724383

ZFP41
Zinc finger protein 41 homolog

3

20

High-throughput

0.609

High

411321

INSR
Insulin receptor

1

11

High-throughput

0.578

High

724380

TAFA3
Chemokine-like protein TAFA-3

2

3

High-throughput

0.574

High

724394

ZN408
Zinc finger protein 408

2

20

High-throughput

0.574

High

160414

AURKA
Aurora kinase A

2

1

High-throughput

0.558

High

724379

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.553

High

135844

WNT7A
Protein Wnt-7a

1

13

High-throughput

0.536

High

378826

HRG
Histidine-rich glycoprotein

1

4

High-throughput

0.536

High

724368

MFAP5
Microfibrillar-associated protein 5

1

5

High-throughput

0.536

High

724381

DB125
Beta-defensin 125

1

1

High-throughput

0.536

High

724385

NET5
Netrin-5

1

19

High-throughput

0.536

High

724392

GREM2
Gremlin-2

1

1

High-throughput

0.536

High

548782

ELN
Elastin

1

9

Small-scale

0.501

High

724374

TRI68
E3 ubiquitin-protein ligase TRIM68

1

2

High-throughput

0.489

High

724377

IGFL3
Insulin growth factor-like family member 3

1

7

High-throughput

0.489

High

724391

EGLN3
Prolyl hydroxylase EGLN3

1

2

High-throughput

0.489

High

724396

DISC1
Disrupted in schizophrenia 1 protein

1

3

High-throughput

0.489

High

724397

ZN224
Zinc finger protein 224

1

12

High-throughput

0.489

High

724399

FBX2
F-box only protein 2

1

16

High-throughput

0.489

High

724365

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

1

Small-scale

0.479

High

724378

ATL5
ADAMTS-like protein 5

1

9

Small-scale

0.479

High

724372

ECM1
Extracellular matrix protein 1

1

1

Small-scale

0.457

High

271738

PRDM1
PR domain zinc finger protein 1

1

20

High-throughput

0.457

High

316808

KLF8
Krueppel-like factor 8

1

20

High-throughput

0.457

High

434978

SP1
Transcription factor Sp1

1

20

High-throughput

0.457

High

724384

SP7
Transcription factor Sp7

1

20

High-throughput

0.457

High

164357

TRI66
Tripartite motif-containing protein 66

1

8

High-throughput

0.437

High

205108

TGON2
Trans-Golgi network integral membrane protein 2

1

14

High-throughput

0.437

High

301649

TRI37
E3 ubiquitin-protein ligase TRIM37

1

12

High-throughput

0.437

High

319136

BRD1
Bromodomain-containing protein 1

1

1

High-throughput

0.437

High

338035

EGFR
Epidermal growth factor receptor

1

12

High-throughput

0.437

High

531747

PDIA4
Protein disulfide-isomerase A4

1

12

High-throughput

0.437

High

649337

RL10
Large ribosomal subunit protein uL16

1

5

High-throughput

0.437

High

724363

PLK1
Serine/threonine-protein kinase PLK1

1

4

High-throughput

0.437

High

724366

RNF4
E3 ubiquitin-protein ligase RNF4

1

3

High-throughput

0.437

High

724369

CUL3
Cullin-3

1

15

High-throughput

0.437

High

724375

SFRP4
Secreted frizzled-related protein 4

1

2

High-throughput

0.437

High

724387

ZDH15
Palmitoyltransferase ZDHHC15

1

3

Small-scale

0.437

High

724393

WDR76
WD repeat-containing protein 76

1

6

High-throughput

0.437

High

724395

FBX6
F-box only protein 6

1

16

High-throughput

0.437

High

724398

HOOK1
Protein Hook homolog 1

1

3

High-throughput

0.437

High

724400

TRI33
E3 ubiquitin-protein ligase TRIM33

1

7

High-throughput

0.437

High

724364

NAL12
NACHT, LRR and PYD domains-containing protein 12

1

1

Small-scale

0.417

High

724390

GFI1
Zinc finger protein Gfi-1

1

20

Small-scale

0.417

High

724362

HD
Huntingtin

1

3

High-throughput

0.407

High

724388

FRMD6
FERM domain-containing protein 6

1

7

High-throughput

0.407

High

724389

NUDC1
NudC domain-containing protein 1

1

1

High-throughput

0.407

High

724403

DUS10
Dual specificity protein phosphatase 10

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024