Protein: SNX4
Sorting nexin-4

Gene: SNX4
Organism: Homo sapiens
Interactions: 68
UniProt ID: O95219

Gene Ontology (top 5):
GO:0005154 - epidermal growth factor receptor binding
GO:0005158 - insulin receptor binding
GO:0005737 - cytoplasm
GO:0005769 - early endosome
GO:0005868 - cytoplasmic dynein complex

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

329866

SNX7
Sorting nexin-7

7

17

Small-scale

0.965

High

329840

SNX30
Sorting nexin-30

5

18

Small-scale

0.925

High

255351

SNX2
Sorting nexin-2

2

19

Small-scale

0.789

High

138425

BIN1
Myc box-dependent-interacting protein 1

2

9

Small-scale

0.628

High

329813

SNX4
Sorting nexin-4

1

18

Small-scale

0.618

High

329867

SNX6
Sorting nexin-6

1

18

Small-scale

0.618

High

329868

SHLB1
Endophilin-B1

2

1

High-throughput

0.606

High

329852

VPP1
V-type proton ATPase 116 kDa subunit a 1

2

0

High-throughput

0.588

High

329847

ANKY2
Ankyrin repeat and MYND domain-containing protein 2

2

5

High-throughput

0.574

High

329836

AR6P1
ADP-ribosylation factor-like protein 6-interacting protein 1

1

3

High-throughput

0.573

High

329829

PTN5
Tyrosine-protein phosphatase non-receptor type 5

1

1

High-throughput

0.541

High

245772

PI51C
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma

1

1

High-throughput

0.536

High

274418

DNJB6
DnaJ homolog subfamily B member 6

1

4

High-throughput

0.536

High

329819

CFTR
Cystic fibrosis transmembrane conductance regulator

1

2

High-throughput

0.536

High

329820

DRD2
D(2) dopamine receptor

1

4

High-throughput

0.536

High

329853

EFMT3
EEF1A lysine methyltransferase 3

1

1

High-throughput

0.536

High

329858

MECR
Enoyl-[acyl-carrier-protein] reductase, mitochondrial

1

3

High-throughput

0.536

High

329861

PAAT
ATPase PAAT

1

1

High-throughput

0.536

High

105008

APRIO
Alternative prion protein

2

4

High-throughput

0.533

High

329825

MAGA6
Melanoma-associated antigen 6

1

1

High-throughput

0.523

High

329830

PSA
Puromycin-sensitive aminopeptidase

1

0

High-throughput

0.513

High

329846

CSN6
COP9 signalosome complex subunit 6

1

0

High-throughput

0.513

High

185312

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

3

High-throughput

0.501

High

329834

DCTN1
Dynactin subunit 1

1

1

Small-scale

0.500

High

329848

KIBRA
Protein KIBRA

1

5

Small-scale

0.500

High

130340

SPT5H
Transcription elongation factor SPT5

1

1

High-throughput

0.494

High

329857

NPAS1
Neuronal PAS domain-containing protein 1

1

1

High-throughput

0.489

High

217652

TGON2
Trans-Golgi network integral membrane protein 2

1

7

High-throughput

0.479

High

240360

PRKN
E3 ubiquitin-protein ligase parkin

1

9

High-throughput

0.479

High

318549

RHBT1
Rho-related BTB domain-containing protein 1

1

10

High-throughput

0.479

High

329814

EGFR
Epidermal growth factor receptor

1

20

Small-scale

0.479

High

329815

INSR
Insulin receptor

1

20

Small-scale

0.479

High

329816

RHOC
Rho-related GTP-binding protein RhoC

1

4

High-throughput

0.479

High

329817

VIME
Vimentin

1

2

High-throughput

0.479

High

329818

PGFRB
Platelet-derived growth factor receptor beta

1

15

Small-scale

0.479

High

329823

PGFRA
Platelet-derived growth factor receptor alpha

1

14

Small-scale

0.479

High

329828

RAB7A
Ras-related protein Rab-7a

1

14

High-throughput

0.479

High

329831

RB11A
Ras-related protein Rab-11A

1

7

High-throughput

0.479

High

329837

EEA1
Early endosome antigen 1

1

2

High-throughput

0.479

High

329841

LTOR1
Ragulator complex protein LAMTOR1

1

6

High-throughput

0.479

High

329842

LMBRL
Protein LMBR1L

1

1

High-throughput

0.479

High

329844

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.479

High

329850

BICD2
Protein bicaudal D homolog 2

1

5

High-throughput

0.479

High

329854

BICD1
Protein bicaudal D homolog 1

1

5

High-throughput

0.479

High

329839

AGK
Acylglycerol kinase, mitochondrial

1

0

Small-scale

0.458

High

329849

DUS18
Dual specificity protein phosphatase 18

1

0

High-throughput

0.458

High

329859

ACE2
Angiotensin-converting enzyme 2

1

0

High-throughput

0.458

High

329860

RB33B
Ras-related protein Rab-33B

1

0

High-throughput

0.458

High

329833

HBA
Hemoglobin subunit alpha

1

1

High-throughput

0.445

High

329851

LPAR1
Lysophosphatidic acid receptor 1

1

4

High-throughput

0.445

High

329869

NPTN
Neuroplastin

1

3

High-throughput

0.445

High

329821

ZEP1
Zinc finger protein 40

1

1

High-throughput

0.439

High

329835

BECN1
Beclin-1

1

0

Small-scale

0.438

High

329822

RFA2
Replication protein A 32 kDa subunit

1

5

High-throughput

0.437

High

329824

RFA3
Replication protein A 14 kDa subunit

1

6

High-throughput

0.437

High

329826

LEPR
Leptin receptor

1

4

Small-scale

0.437

High

329855

SCLT1
Sodium channel and clathrin linker 1

1

3

High-throughput

0.437

High

329827

PPT1
Palmitoyl-protein thioesterase 1

1

0

High-throughput

0.426

High

329838

P3H1
Prolyl 3-hydroxylase 1

1

0

High-throughput

0.426

High

329865

FZD10
Frizzled-10

1

0

High-throughput

0.426

High

329863

DISC1
Disrupted in schizophrenia 1 protein

1

4

High-throughput

0.417

High

329832

HBB
Hemoglobin subunit beta

1

1

High-throughput

0.407

High

329862

CYBP
Calcyclin-binding protein

2

0

High-throughput

0.328

High

329864

ABCBA
ATP-binding cassette sub-family B member 10, mitochondrial

2

0

High-throughput

0.328

High

329843

DG2L6
Diacylglycerol O-acyltransferase 2-like protein 6

2

0

High-throughput

0.316

High

329856

TCPQM
T-complex protein 1 subunit theta-like 2

1

0

High-throughput

0.279

Low

329845

Q75KN0
Uncharacterized protein FLJ10842

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025