Protein: ACM4
Muscarinic acetylcholine receptor M4

Gene: ACM4, CHRM4
Organism: Homo sapiens
Interactions: 96
UniProt ID: P08173

Gene Ontology (top 5):
GO:0004993 - G protein-coupled serotonin receptor activity
GO:0005886 - plasma membrane
GO:0007165 - signal transduction
GO:0007166 - cell surface receptor signaling pathway
GO:0007187 - G protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

295788

ST17B
Serine/threonine-protein kinase 17B

2

2

High-throughput

0.811

High

436898

TTK
Dual specificity protein kinase TTK

2

4

High-throughput

0.726

High

436887

ACM4
Muscarinic acetylcholine receptor M4

1

16

Small-scale

0.647

High

436907

TBB3
Tubulin beta-3 chain

2

4

High-throughput

0.628

High

436937

CIP2A
Protein CIP2A

2

1

High-throughput

0.628

High

436960

VEZA
Vezatin

2

1

High-throughput

0.628

High

126503

QSOX1
Sulfhydryl oxidase 1

1

1

High-throughput

0.625

High

436896

5HT2C
5-hydroxytryptamine receptor 2C

1

19

Small-scale

0.618

High

436900

KNTC1
Kinetochore-associated protein 1

2

0

High-throughput

0.602

High

436914

MRP7
ATP-binding cassette sub-family C member 10

2

0

High-throughput

0.602

High

436925

SARM1
NAD(+) hydrolase SARM1

2

0

High-throughput

0.602

High

436936

EXOC6
Exocyst complex component 6

2

0

High-throughput

0.602

High

436945

XPO6
Exportin-6

2

0

High-throughput

0.602

High

436946

S29A1
Equilibrative nucleoside transporter 1

2

0

High-throughput

0.602

High

256721

CAND2
Cullin-associated NEDD8-dissociated protein 2

2

6

High-throughput

0.574

High

436893

ERF3A
Eukaryotic peptide chain release factor GTP-binding subunit ERF3A

2

3

High-throughput

0.574

High

436904

TBA4A
Tubulin alpha-4A chain

2

3

High-throughput

0.574

High

436916

ECM29
Proteasome adapter and scaffold protein ECM29

2

7

High-throughput

0.574

High

436921

MBOA5
Lysophospholipid acyltransferase 5

2

4

High-throughput

0.574

High

436926

THADA
tRNA

2

1

High-throughput

0.574

High

436927

CERS6
Ceramide synthase 6

2

10

High-throughput

0.574

High

436929

HEAT3
HEAT repeat-containing protein 3

2

1

High-throughput

0.574

High

436944

IPO9
Importin-9

2

10

High-throughput

0.574

High

436952

GCP2
Gamma-tubulin complex component 2

2

2

High-throughput

0.574

High

436958

PIGM
GPI mannosyltransferase 1

2

1

High-throughput

0.574

High

436963

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

2

1

High-throughput

0.574

High

436965

IPO11
Importin-11

2

9

High-throughput

0.574

High

436966

XPO7
Exportin-7

2

4

High-throughput

0.574

High

436967

PP6R1
Serine/threonine-protein phosphatase 6 regulatory subunit 1

2

2

High-throughput

0.574

High

436968

UBP24
Ubiquitin carboxyl-terminal hydrolase 24

2

3

High-throughput

0.574

High

155515

TNPO2
Transportin-2

2

7

High-throughput

0.558

High

436890

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.541

High

436894

RAB3A
Ras-related protein Rab-3A

1

4

High-throughput

0.541

High

436899

TSN7
Tetraspanin-7

1

14

High-throughput

0.541

High

436901

CD81
CD81 antigen

1

14

High-throughput

0.541

High

436902

B2MG
Beta-2-microglobulin [Cleaved into: Beta-2-microglobulin form pI 5.3]

1

2

High-throughput

0.541

High

436942

SYN2
Synapsin-2

1

1

High-throughput

0.541

High

436956

YIPF3
Protein YIPF3

1

4

High-throughput

0.541

High

436961

RTN4
Reticulon-4

1

5

High-throughput

0.541

High

415172

ATPB
ATP synthase subunit beta, mitochondrial

1

6

High-throughput

0.536

High

436888

ADT1
ADP/ATP translocase 1

1

4

High-throughput

0.536

High

436891

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

1

7

High-throughput

0.536

High

436895

RAB3B
Ras-related protein Rab-3B

1

3

High-throughput

0.536

High

436915

RIF1
Telomere-associated protein RIF1

1

1

High-throughput

0.536

High

436928

TBA1A
Tubulin alpha-1A chain

1

3

High-throughput

0.536

High

436953

YIPF4
Protein YIPF4

1

3

High-throughput

0.536

High

282433

ERG24
Delta(14)-sterol reductase TM7SF2

1

0

High-throughput

0.518

High

436892

CD59
CD59 glycoprotein

1

0

High-throughput

0.518

High

436909

EFR3A
Protein EFR3 homolog A

1

0

High-throughput

0.513

High

436930

T179B
Transmembrane protein 179B

1

0

High-throughput

0.513

High

436935

MIGA1
Mitoguardin 1

1

0

High-throughput

0.513

High

436943

COG3
Conserved oligomeric Golgi complex subunit 3

1

0

High-throughput

0.513

High

436913

PR15B
Protein phosphatase 1 regulatory subunit 15B

2

1

High-throughput

0.504

High

436919

RHBD2
Rhomboid domain-containing protein 2

1

3

High-throughput

0.494

High

436951

SMIM7
Small integral membrane protein 7

1

1

High-throughput

0.494

High

162345

XPO1
Exportin-1

1

8

High-throughput

0.489

High

436889

ADT3
ADP/ATP translocase 3

1

4

High-throughput

0.489

High

436903

ACTA
Actin, aortic smooth muscle

1

10

High-throughput

0.489

High

436905

PRKDC
DNA-dependent protein kinase catalytic subunit

1

5

High-throughput

0.489

High

436934

ARL10
ADP-ribosylation factor-like protein 10

1

8

High-throughput

0.489

High

436938

IPO4
Importin-4

1

7

High-throughput

0.489

High

436939

COG1
Conserved oligomeric Golgi complex subunit 1

1

1

High-throughput

0.489

High

436940

GBF1
Golgi-specific brefeldin A-resistance guanine nucleotide exchange factor 1

1

1

High-throughput

0.489

High

436941

GCN1
Stalled ribosome sensor GCN1

1

3

High-throughput

0.489

High

436950

CND3
Condensin complex subunit 3

1

1

High-throughput

0.489

High

436955

XPO4
Exportin-4

1

3

High-throughput

0.489

High

436962

FIRRM
FIGNL1-interacting regulator of recombination and mitosis

1

1

High-throughput

0.489

High

436964

GCP4
Gamma-tubulin complex component 4

1

2

High-throughput

0.489

High

436947

SH3G1
Endophilin-A2

1

20

Small-scale

0.479

High

436948

SH3G2
Endophilin-A1

1

20

Small-scale

0.479

High

436949

SH3G3
Endophilin-A3

1

20

Small-scale

0.479

High

351489

NGF
Beta-nerve growth factor

1

0

Small-scale

0.458

High

436908

SNX1
Sorting nexin-1

1

3

Small-scale

0.437

High

436912

GASP1
G-protein coupled receptor-associated sorting protein 1

1

11

Small-scale

0.437

High

436911

Q4LE60
TNPO2 variant protein

1

7

High-throughput

0.407

High

157698

GEMI2
Gem-associated protein 2

2

0

High-throughput

0.328

High

176536

FANCA
Fanconi anemia group A protein

2

0

High-throughput

0.328

High

199265

ZW10
Centromere/kinetochore protein zw10 homolog

2

0

High-throughput

0.328

High

436897

GLPK
Glycerol kinase

2

0

High-throughput

0.328

High

436910

COG2
Conserved oligomeric Golgi complex subunit 2

2

0

High-throughput

0.328

High

436917

LPCT4
Lysophospholipid acyltransferase LPCAT4

2

0

High-throughput

0.328

High

436918

F91A1
Protein FAM91A1

2

0

High-throughput

0.328

High

436920

RINT1
RAD50-interacting protein 1

2

0

High-throughput

0.328

High

436922

PDXD1
Pyridoxal-dependent decarboxylase domain-containing protein 1

2

0

High-throughput

0.328

High

436923

INT5
Integrator complex subunit 5

2

0

High-throughput

0.328

High

436924

BRAT1
BRCA1-associated ATM activator 1

2

0

High-throughput

0.328

High

436932

DAAF5
Dynein axonemal assembly factor 5

2

0

High-throughput

0.328

High

253961

MTG16
Protein CBFA2T3

1

0

High-throughput

0.282

High

436906

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

1

0

High-throughput

0.282

High

436933

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.282

High

436957

METL9
Protein-L-histidine N-pros-methyltransferase

1

0

High-throughput

0.282

High

436969

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

0

High-throughput

0.282

High

436931

ADCK1
AarF domain-containing protein kinase 1

1

0

High-throughput

0.279

Low

436954

ALG8
Dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase

1

0

High-throughput

0.279

Low

436959

COG4
Conserved oligomeric Golgi complex subunit 4

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024