Protein: LIFR
Leukemia inhibitory factor receptor (LIF receptor) (LIF-R) (CD antigen CD118)

Gene: LIFR
Organism: Homo sapiens
Interactions: 35
UniProt ID: P42702

Gene Ontology (top 5):
GO:0004896 - cytokine receptor activity
GO:0004923 - leukemia inhibitory factor receptor activity
GO:0004924 - oncostatin-M receptor activity
GO:0005127 - ciliary neurotrophic factor receptor binding
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

645940

CNTFR
Ciliary neurotrophic factor receptor subunit alpha

2

19

Small-scale

0.812

High

770184

IL6RB
Interleukin-6 receptor subunit beta

2

16

Small-scale

0.754

High

542650

LIF
Leukemia inhibitory factor

5

2

Small-scale

0.707

High

789676

HFE
Hereditary hemochromatosis protein

1

5

High-throughput

0.691

High

642881

CNTF
Ciliary neurotrophic factor

3

3

Small-scale

0.660

High

532857

ONCM
Oncostatin-M

3

4

Small-scale

0.646

High

196967

PRP4
U4/U6 small nuclear ribonucleoprotein Prp4

1

2

High-throughput

0.618

High

338085

EGFR
Epidermal growth factor receptor

1

20

High-throughput

0.618

High

665815

PTN6
Tyrosine-protein phosphatase non-receptor type 6

1

18

Small-scale

0.618

High

789669

DEF1
Neutrophil defensin 1

2

0

High-throughput

0.602

High

328113

SG1D1
Secretoglobin family 1D member 1

2

1

High-throughput

0.574

High

789679

TAFA4
Chemokine-like protein TAFA-4

2

4

High-throughput

0.574

High

150897

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

16

High-throughput

0.553

High

789672

SLAF1
Signaling lymphocytic activation molecule

1

12

High-throughput

0.536

High

789675

CTF1
Cardiotrophin-1

1

3

High-throughput

0.536

High

789670

SC61B
Protein transport protein Sec61 subunit beta

2

1

High-throughput

0.533

High

789688

MB212
Protein mab-21-like 2

1

0

High-throughput

0.513

High

324264

BAG3
BAG family molecular chaperone regulator 3

1

2

High-throughput

0.489

High

600094

TAF1
Transcription initiation factor TFIID subunit 1

1

3

High-throughput

0.489

High

789677

TAFA2
Chemokine-like protein TAFA-2

1

4

High-throughput

0.489

High

789683

TF7L2
Transcription factor 7-like 2

1

1

High-throughput

0.489

High

789685

FBX2
F-box only protein 2

1

12

High-throughput

0.489

High

789681

SORT
Sortilin

1

0

Small-scale

0.480

High

205139

TGON2
Trans-Golgi network integral membrane protein 2

1

7

High-throughput

0.479

High

789671

STX4
Syntaxin-4

1

6

High-throughput

0.479

High

239838

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

9

High-throughput

0.445

High

789674

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

11

High-throughput

0.445

High

130785

PSDE
26S proteasome non-ATPase regulatory subunit 14

1

2

High-throughput

0.437

High

789678

DHB11
Estradiol 17-beta-dehydrogenase 11

1

1

High-throughput

0.437

High

789684

FBX6
F-box only protein 6

1

12

High-throughput

0.437

High

789686

DJC16
DnaJ homolog subfamily C member 16

1

1

High-throughput

0.437

High

789673

OS9
Protein OS-9

1

0

High-throughput

0.279

Low

789687

GOT1B
Vesicle transport protein GOT1B

1

0

High-throughput

0.279

Low

789680

SEC62
Translocation protein SEC62

1

0

High-throughput

0.249

Low

789682

TMT1A
Thiol S-methyltransferase TMT1A

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024