Protein: GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha (Guanine nucleotide-binding protein alpha-q)

Gene: GNAQ
Organism: Homo sapiens
Interactions: 113
UniProt ID: P50148

Gene Ontology (top 5):
GO:0001508 - action potential
GO:0001664 - G protein-coupled receptor binding
GO:0001750 - photoreceptor outer segment
GO:0003924 - GTPase activity
GO:0005096 - GTPase activator activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

600873

TA2R
Thromboxane A2 receptor

8

20

Small-scale

0.963

High

626634

ARBK1
Beta-adrenergic receptor kinase 1

4

4

Small-scale

0.908

High

837648

RIC8A
Synembryn-A

3

15

Small-scale

0.880

High

834936

RGS4
Regulator of G-protein signaling 4

3

20

Small-scale

0.865

High

837649

PLCB1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-1

2

3

Small-scale

0.825

High

837600

GBB1
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

2

20

High-throughput

0.811

High

837623

P2RY8
P2Y purinoceptor 8

2

20

High-throughput

0.789

High

180656

RGS16
Regulator of G-protein signaling 16

1

20

Small-scale

0.724

High

304718

S1PR2
Sphingosine 1-phosphate receptor 2

1

20

High-throughput

0.691

High

598719

S1PR1
Sphingosine 1-phosphate receptor 1

1

20

High-throughput

0.691

High

837655

RIC8B
Synembryn-B

1

15

Small-scale

0.680

High

782018

RGS2
Regulator of G-protein signaling 2

1

20

Small-scale

0.647

High

834946

RGS7
Regulator of G-protein signaling 7

1

20

Small-scale

0.647

High

837611

GRM7
Metabotropic glutamate receptor 7

1

1

Small-scale

0.647

High

837641

MRGX1
Mas-related G-protein coupled receptor member X1

1

20

Small-scale

0.647

High

837653

RGS18
Regulator of G-protein signaling 18

1

20

Small-scale

0.647

High

837590

GBG4

2

20

High-throughput

0.628

High

837602

GBG3

2

20

High-throughput

0.628

High

837651

DUS22
Dual specificity protein phosphatase 22

2

15

High-throughput

0.628

High

167075

ARHGB
Rho guanine nucleotide exchange factor 11

1

20

Small-scale

0.618

High

182446

RGS5
Regulator of G-protein signaling 5

1

20

Small-scale

0.618

High

560863

GBB3
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3

1

20

Small-scale

0.618

High

626831

PAR1
Proteinase-activated receptor 1

1

20

Small-scale

0.618

High

674835

AGTR1
Type-1 angiotensin II receptor

1

15

Small-scale

0.618

High

686272

VIPR1
Vasoactive intestinal polypeptide receptor 1

1

9

Small-scale

0.618

High

686617

CCR1
C-C chemokine receptor type 1

1

19

High-throughput

0.618

High

687035

CXCR5
C-X-C chemokine receptor type 5

1

14

Small-scale

0.618

High

714727

CRFR1
Corticotropin-releasing factor receptor 1

1

9

Small-scale

0.618

High

793174

PI2R
Prostacyclin receptor

1

20

Small-scale

0.618

High

837604

PLCB2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2

1

3

Small-scale

0.618

High

837608

AKP13
A-kinase anchor protein 13

1

16

Small-scale

0.618

High

837615

AGRF1
Adhesion G-protein coupled receptor F1

1

8

Small-scale

0.618

High

837637

ARHG1
Rho guanine nucleotide exchange factor 1

1

20

Small-scale

0.618

High

837638

KISSR
KiSS-1 receptor

1

20

Small-scale

0.618

High

837658

ARHGC
Rho guanine nucleotide exchange factor 12

1

13

Small-scale

0.618

High

837613

DGUOK
Deoxyguanosine kinase, mitochondrial

2

1

High-throughput

0.611

High

837621

MOT14
Monocarboxylate transporter 14

2

4

High-throughput

0.611

High

837656

KTU
Protein kintoun

2

1

High-throughput

0.611

High

837657

TA2R7
Taste receptor type 2 member 7

2

1

High-throughput

0.611

High

837663

NUFP1
FMR1-interacting protein NUFIP1

2

3

High-throughput

0.611

High

837654

ATG3
Ubiquitin-like-conjugating enzyme ATG3

2

0

High-throughput

0.602

High

837618

CXB7
Gap junction beta-7 protein

2

3

High-throughput

0.574

High

837606

BTK
Tyrosine-protein kinase BTK

1

1

Small-scale

0.561

High

837612

CYH1
Cytohesin-1

1

4

Small-scale

0.561

High

837645

CYH2
Cytohesin-2

1

4

Small-scale

0.561

High

447231

HXB5
Homeobox protein Hox-B5

2

4

High-throughput

0.558

High

837629

S2541
Mitochondrial carrier protein SCaMC-3L

2

3

High-throughput

0.558

High

837630

T185A
Transmembrane protein 185A

2

3

High-throughput

0.558

High

837643

UIF
UAP56-interacting factor

2

3

High-throughput

0.558

High

837644

CCNL2
Cyclin-L2

2

2

High-throughput

0.558

High

837631

WDR36
WD repeat-containing protein 36

1

4

Small-scale

0.553

High

837591

GBG10

1

20

High-throughput

0.536

High

837593

GPM6A
Neuronal membrane glycoprotein M6-a

1

2

High-throughput

0.536

High

837595

GBG2
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2

1

20

High-throughput

0.536

High

837601

GBG1
Guanine nucleotide-binding protein G(T) subunit gamma-T1

1

20

High-throughput

0.536

High

837603

GBG5

1

20

High-throughput

0.536

High

837627

ZDH23
Palmitoyltransferase ZDHHC23

1

5

High-throughput

0.536

High

837636

KIFA3
Kinesin-associated protein 3

1

1

High-throughput

0.536

High

837639

ISG20
Interferon-stimulated gene 20 kDa protein

1

3

High-throughput

0.536

High

837659

GBG12

1

20

High-throughput

0.536

High

837664

GBG8
Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-8

1

20

High-throughput

0.536

High

837665

PCDGK
Protocadherin gamma-C3

1

1

High-throughput

0.536

High

837666

TACC3
Transforming acidic coiled-coil-containing protein 3

1

1

High-throughput

0.536

High

837616

IQEC1
IQ motif and SEC7 domain-containing protein 1

2

3

Small-scale

0.533

High

837592

PPT1
Palmitoyl-protein thioesterase 1

1

0

High-throughput

0.518

High

837594

LUM
Lumican

1

0

High-throughput

0.518

High

837625

HOT
Hydroxyacid-oxoacid transhydrogenase, mitochondrial

1

0

High-throughput

0.518

High

837647

5NT3A
Cytosolic 5'-nucleotidase 3A

1

0

High-throughput

0.518

High

487925

RARA
Retinoic acid receptor alpha

1

6

Small-scale

0.515

High

361840

FIBB
Fibrinogen beta chain [Cleaved into: Fibrinopeptide B; Fibrinogen beta chain]

1

0

High-throughput

0.513

High

837619

RN111
E3 ubiquitin-protein ligase Arkadia

1

0

High-throughput

0.513

High

837622

SPRE2
Sprouty-related, EVH1 domain-containing protein 2

1

0

High-throughput

0.513

High

837628

ZN843
Zinc finger protein 843

1

0

High-throughput

0.513

High

837632

LHPL5
LHFPL tetraspan subfamily member 5 protein

1

0

High-throughput

0.513

High

837633

EXOC6
Exocyst complex component 6

1

0

High-throughput

0.513

High

837652

PLCC
1-acyl-sn-glycerol-3-phosphate acyltransferase gamma

1

0

High-throughput

0.513

High

118707

AIP
AH receptor-interacting protein

1

6

Small-scale

0.501

High

827127

ARRB1
Beta-arrestin-1

1

0

Small-scale

0.493

High

837609

MED21
Mediator of RNA polymerase II transcription subunit 21

1

1

High-throughput

0.489

High

837626

CMIP
C-Maf-inducing protein

1

3

High-throughput

0.489

High

837640

CERS2
Ceramide synthase 2

1

3

High-throughput

0.489

High

837650

ANLN
Anillin

1

10

High-throughput

0.489

High

118238

HAX1
HCLS1-associated protein X-1

1

2

High-throughput

0.479

High

155304

NRP1
Neuropilin-1

1

5

High-throughput

0.479

High

212307

CYH3
Cytohesin-3

1

4

Small-scale

0.479

High

308511

KI20A
Kinesin-like protein KIF20A

1

20

High-throughput

0.479

High

349192

RASH
GTPase HRas

1

12

High-throughput

0.479

High

557445

PECA1
Platelet endothelial cell adhesion molecule

1

2

Small-scale

0.479

High

594717

ATP4A
Potassium-transporting ATPase alpha chain 1

1

6

Small-scale

0.479

High

650684

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

5

High-throughput

0.479

High

787190

PK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

1

3

Small-scale

0.479

High

837598

ABCE1
ATP-binding cassette sub-family E member 1

1

2

High-throughput

0.479

High

837599

ARF6
ADP-ribosylation factor 6

1

1

Small-scale

0.479

High

837607

CD47
Leukocyte surface antigen CD47

1

1

Small-scale

0.479

High

837620

TRI67
Tripartite motif-containing protein 67

1

6

High-throughput

0.479

High

837660

HDAC6
Histone deacetylase 6

1

7

High-throughput

0.479

High

837662

UBQL2
Ubiquilin-2

1

2

High-throughput

0.479

High

837646

TTC1
Tetratricopeptide repeat protein 1

1

8

Small-scale

0.470

High

655273

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

0

Small-scale

0.458

High

239856

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

8

High-throughput

0.445

High

496575

TAU
Microtubule-associated protein tau

1

16

High-throughput

0.445

High

837596

CD81
CD81 antigen

1

7

High-throughput

0.445

High

837605

ANK2
Ankyrin-2

1

2

High-throughput

0.445

High

837610

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

12

High-throughput

0.445

High

837617

PKHA7
Pleckstrin homology domain-containing family A member 7

1

14

High-throughput

0.445

High

837642

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

15

High-throughput

0.445

High

61097

PSD1
PH and SEC7 domain-containing protein 1

1

4

Small-scale

0.437

High

837635

ESR2
Estrogen receptor beta

1

10

High-throughput

0.437

High

837634

CMAP3
Ciliary microtubule-associated protein 3

2

0

High-throughput

0.318

High

837597

CKS1
Cyclin-dependent kinases regulatory subunit 1

1

0

High-throughput

0.279

Low

837614

TIGD5
Tigger transposable element-derived protein 5

1

0

High-throughput

0.279

Low

837624

C1QL4
Complement C1q-like protein 4

1

0

High-throughput

0.279

Low

837661

PARP2
Poly [ADP-ribose] polymerase 2

1

0

Small-scale

0.261

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024