Protein: BAD
Bcl2-associated agonist of cell death (BAD) (Bcl-2-binding component 6) (Bcl-2-like protein 8) (Bcl2-L-8) (Bcl-xL/Bcl-2-associated death promoter) (Bcl2 antagonist of cell death)

Gene: BAD
Organism: Homo sapiens
Interactions: 106
UniProt ID: Q92934

Gene Ontology (top 5):
GO:0001836 - release of cytochrome c from mitochondria
GO:0005543 - phospholipid binding
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

992105

B2CL1
Bcl-2-like protein 1

39

8

Small-scale

0.995

High

489443

BCL2
Apoptosis regulator Bcl-2

12

8

Small-scale

0.982

High

1271712

B2CL2
Bcl-2-like protein 2

9

8

Small-scale

0.968

High

992182

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

2

8

Small-scale

0.767

High

1083078

B2LA1
Bcl-2-related protein A1

2

8

Small-scale

0.767

High

927377

1433Z
14-3-3 protein zeta/delta

16

9

Small-scale

0.762

High

684252

1433S
14-3-3 protein sigma

9

9

Small-scale

0.756

High

647168

1433T
14-3-3 protein theta

11

9

Small-scale

0.755

High

683602

1433B
14-3-3 protein beta/alpha

9

9

Small-scale

0.753

High

681964

AKT1
RAC-alpha serine/threonine-protein kinase

7

7

Small-scale

0.750

High

982357

1433F
14-3-3 protein eta

9

9

Small-scale

0.749

High

992027

BAX
Apoptosis regulator BAX

2

8

Small-scale

0.737

High

904949

1433G
14-3-3 protein gamma

6

9

High-throughput

0.732

High

909882

1433E
14-3-3 protein epsilon

9

0

Small-scale

0.721

High

1026198

PAK1
Serine/threonine-protein kinase PAK 1

3

5

Small-scale

0.672

High

568755

KAPCA
cAMP-dependent protein kinase catalytic subunit alpha

3

5

Small-scale

0.646

High

374638

RAF1
RAF proto-oncogene serine/threonine-protein kinase

2

2

Small-scale

0.633

High

742450

SYUA
Alpha-synuclein

3

1

Small-scale

0.633

High

725684

ACTN2
Alpha-actinin-2

2

0

High-throughput

0.580

High

1071315

K1H1
Keratin, type I cuticular Ha1

2

0

High-throughput

0.580

High

135478

PPP6
Serine/threonine-protein phosphatase 6 catalytic subunit

2

2

High-throughput

0.571

High

312349

IPO7
Importin-7

2

2

High-throughput

0.571

High

504514

HSP7C
Heat shock cognate 71 kDa protein

2

1

High-throughput

0.571

High

564144

HSP76
Heat shock 70 kDa protein 6

2

1

High-throughput

0.571

High

610759

KAPCB
cAMP-dependent protein kinase catalytic subunit beta

2

5

High-throughput

0.571

High

672226

2AAA
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform

2

1

High-throughput

0.571

High

672454

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

2

1

High-throughput

0.571

High

930943

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

2

1

High-throughput

0.571

High

973971

M2OM
Mitochondrial 2-oxoglutarate/malate carrier protein

2

1

High-throughput

0.571

High

1032380

2A5G
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform

2

1

High-throughput

0.571

High

1060858

IMB1
Importin subunit beta-1

2

1

High-throughput

0.571

High

1082528

2A5E
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform

2

1

High-throughput

0.571

High

1135281

ATD3B
ATPase family AAA domain-containing protein 3B

2

2

High-throughput

0.571

High

1273029

IPO9
Importin-9

2

2

High-throughput

0.571

High

1273034

ATD3A
ATPase family AAA domain-containing protein 3A

2

2

High-throughput

0.571

High

1273036

DIC
Mitochondrial dicarboxylate carrier

2

1

High-throughput

0.571

High

388631

HSPB1
Heat shock protein beta-1

2

0

High-throughput

0.547

High

441137

CY1
Cytochrome c1, heme protein, mitochondrial

2

0

High-throughput

0.547

High

498324

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

2

0

High-throughput

0.547

High

499985

CH60
60 kDa heat shock protein, mitochondrial

2

0

High-throughput

0.547

High

653332

PYR1
Multifunctional protein CAD

2

0

High-throughput

0.547

High

657400

ABCD3
ATP-binding cassette sub-family D member 3

2

0

High-throughput

0.547

High

839027

EMD
Emerin

2

0

High-throughput

0.547

High

879703

ATPK
ATP synthase subunit f, mitochondrial

2

0

High-throughput

0.547

High

884050

GEMI4
Gem-associated protein 4

2

0

High-throughput

0.547

High

944357

PRKDC
DNA-dependent protein kinase catalytic subunit

2

0

High-throughput

0.547

High

959273

S25A3
Solute carrier family 25 member 3

2

0

High-throughput

0.547

High

997841

RBBP4
Histone-binding protein RBBP4

2

0

High-throughput

0.547

High

1025187

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

2

0

High-throughput

0.547

High

1084857

SMN
Survival motor neuron protein

2

0

High-throughput

0.547

High

1121316

AGK
Acylglycerol kinase, mitochondrial

2

0

High-throughput

0.547

High

1157584

CAVN1
Caveolae-associated protein 1

2

0

High-throughput

0.547

High

1242969

MCU
Calcium uniporter protein, mitochondrial

2

0

High-throughput

0.547

High

1245324

KNL1
Kinetochore scaffold 1

2

0

High-throughput

0.547

High

1270351

HDAC2
Histone deacetylase 2

2

0

High-throughput

0.547

High

1273027

HOOK2
Protein Hook homolog 2

2

0

High-throughput

0.547

High

1273031

OSBL8
Oxysterol-binding protein-related protein 8

2

0

High-throughput

0.547

High

1273037

DDX20
Probable ATP-dependent RNA helicase DDX20

2

0

High-throughput

0.547

High

1273041

TIM9
Mitochondrial import inner membrane translocase subunit Tim9

2

0

High-throughput

0.547

High

863791

LIMK1
LIM domain kinase 1

1

3

High-throughput

0.536

High

1273032

GAN
Gigaxonin

1

1

High-throughput

0.536

High

758301

CDN1A
Cyclin-dependent kinase inhibitor 1

1

0

High-throughput

0.518

High

1049289

KEAP1
Kelch-like ECH-associated protein 1

1

0

High-throughput

0.518

High

1147404

CR3L3
Cyclic AMP-responsive element-binding protein 3-like protein 3

1

0

High-throughput

0.518

High

906062

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

1

High-throughput

0.515

High

213854

SYNC
Asparagine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.513

High

235991

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

0

High-throughput

0.513

High

1273030

SORT
Sortilin

1

0

High-throughput

0.513

High

1273038

NDUAC
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12

1

0

High-throughput

0.513

High

488768

ARAF
Serine/threonine-protein kinase A-Raf

1

2

Small-scale

0.501

High

507580

PIM1
Serine/threonine-protein kinase pim-1

1

4

Small-scale

0.501

High

542905

BRAF
Serine/threonine-protein kinase B-raf

1

2

Small-scale

0.501

High

784059

KPCI
Protein kinase C iota type

1

5

Small-scale

0.501

High

1073460

KS6A1
Ribosomal protein S6 kinase alpha-1

1

6

Small-scale

0.501

High

1273035

PIM2
Serine/threonine-protein kinase pim-2

1

1

Small-scale

0.501

High

395383

A4
Amyloid-beta precursor protein

1

0

High-throughput

0.493

High

427914

CAN1
Calpain-1 catalytic subunit

1

0

High-throughput

0.493

High

154226

CHK1
Serine/threonine-protein kinase Chk1

1

0

Small-scale

0.480

High

225203

BNI3L
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like

1

0

Small-scale

0.480

High

206763

B2L11
Bcl-2-like protein 11

1

0

Small-scale

0.479

High

262297

ULK1
Serine/threonine-protein kinase ULK1

1

2

Small-scale

0.479

High

566443

KPCA
Protein kinase C alpha type

1

4

High-throughput

0.479

High

969099

KPCE
Protein kinase C epsilon type

1

4

Small-scale

0.479

High

1068489

KPCD1
Serine/threonine-protein kinase D1

1

4

Small-scale

0.479

High

685744

PRDX2
Peroxiredoxin-2

1

0

High-throughput

0.460

High

1145567

STEA3
Metalloreductase STEAP3

1

0

High-throughput

0.460

High

875186

TERA
Transitional endoplasmic reticulum ATPase

1

0

High-throughput

0.458

High

924752

GRB2
Growth factor receptor-bound protein 2

1

0

High-throughput

0.458

High

1054176

BECN1
Beclin-1

1

0

Small-scale

0.458

High

1234675

CISD2
CDGSH iron-sulfur domain-containing protein 2

1

0

Small-scale

0.458

High

1273026

BAD
Bcl2-associated agonist of cell death

1

0

High-throughput

0.458

High

1273040

CBY1
Protein chibby homolog 1

1

0

High-throughput

0.458

High

270433

KS6A5
Ribosomal protein S6 kinase alpha-5

1

5

Small-scale

0.457

High

1273033

WNK1
Serine/threonine-protein kinase WNK1

1

3

High-throughput

0.457

High

1187463

APTX
Aprataxin

2

0

High-throughput

0.328

High

266219

ERLN1
Erlin-1

2

0

High-throughput

0.298

High

296093

MTA2
Metastasis-associated protein MTA2

2

0

High-throughput

0.298

High

315043

SGPL1
Sphingosine-1-phosphate lyase 1

2

0

High-throughput

0.298

High

1139851

OBI1
ORC ubiquitin ligase 1

2

0

High-throughput

0.298

High

1272251

GSLG1
Golgi apparatus protein 1

2

0

High-throughput

0.298

High

1273039

AKP8L
A-kinase anchor protein 8-like

2

0

High-throughput

0.298

High

967322

EWS
RNA-binding protein EWS

1

0

High-throughput

0.282

High

893823

S10AA
Protein S100-A10

1

0

Small-scale

0.275

Low

902704

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.265

Low

1273028

GIMA5
GTPase IMAP family member 5

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024