Protein: I20L2
Interferon-stimulated 20 kDa exonuclease-like 2 (EC 3.1.-.-)

Gene: I20L2, ISG20L2
Organism: Homo sapiens
Interactions: 52
UniProt ID: Q9H9L3

Gene Ontology (top 5):
GO:0000175 - 3'-5'-RNA exonuclease activity
GO:0003723 - RNA binding
GO:0004527 - exonuclease activity
GO:0005634 - nucleus
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

521949

H14
Histone H1.4

2

8

High-throughput

0.628

High

1437152

SSF1
Suppressor of SWI4 1 homolog

2

2

High-throughput

0.611

High

373178

MYC
Myc proto-oncogene protein

2

5

High-throughput

0.584

High

134958

EMAL1
Echinoderm microtubule-associated protein-like 1

2

1

High-throughput

0.584

High

396975

ESR1
Estrogen receptor

2

3

High-throughput

0.571

High

290741

SURF6
Surfeit locus protein 6

1

1

High-throughput

0.536

High

447461

NPM
Nucleophosmin

1

3

High-throughput

0.536

High

833196

MNDA
Myeloid cell nuclear differentiation antigen

1

3

High-throughput

0.536

High

854312

KI67
Proliferation marker protein Ki-67

1

1

High-throughput

0.536

High

992966

RACK1
Small ribosomal subunit protein RACK1

1

2

High-throughput

0.536

High

1016237

RL19
Large ribosomal subunit protein eL19

1

3

High-throughput

0.536

High

1025593

CDK16
Cyclin-dependent kinase 16

1

1

High-throughput

0.536

High

1117671

NOG2
Nucleolar GTP-binding protein 2

1

1

High-throughput

0.536

High

1130852

RRP5
Protein RRP5 homolog

1

3

High-throughput

0.536

High

1360485

PSPC1
Paraspeckle component 1

1

9

High-throughput

0.536

High

1437155

ZBT47
Zinc finger and BTB domain-containing protein 47

1

3

High-throughput

0.536

High

415869

HSPB1
Heat shock protein beta-1

1

0

High-throughput

0.518

High

596363

H12
Histone H1.2

1

8

High-throughput

0.515

High

657312

KALM
Anosmin-1

1

1

High-throughput

0.489

High

191100

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

1

High-throughput

0.479

High

401503

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

5

High-throughput

0.479

High

406659

MYCN
N-myc proto-oncogene protein

1

5

High-throughput

0.479

High

440733

FYN
Tyrosine-protein kinase Fyn

1

5

High-throughput

0.479

High

557474

SRC
Proto-oncogene tyrosine-protein kinase Src

1

5

High-throughput

0.479

High

594105

NCK1
SH2/SH3 adapter protein NCK1

1

5

High-throughput

0.479

High

810390

RL3
Large ribosomal subunit protein uL3

1

4

High-throughput

0.479

High

855760

CRK
Adapter molecule crk

1

3

High-throughput

0.479

High

883693

CENPA
Histone H3-like centromeric protein A

1

6

High-throughput

0.479

High

937919

FOXA1
Hepatocyte nuclear factor 3-alpha

1

3

High-throughput

0.479

High

979251

RS6
Small ribosomal subunit protein eS6

1

2

High-throughput

0.479

High

980347

H4
Histone H4

1

1

High-throughput

0.479

High

982834

RS24
Small ribosomal subunit protein eS24

1

2

High-throughput

0.479

High

984997

RL31
Large ribosomal subunit protein eL31

1

2

High-throughput

0.479

High

986733

PPIA
Peptidyl-prolyl cis-trans isomerase A

1

1

High-throughput

0.479

High

987951

GRB2
Growth factor receptor-bound protein 2

1

7

High-throughput

0.479

High

1017219

H33
Histone H3.3

1

6

High-throughput

0.479

High

1087558

GRSF1
G-rich sequence factor 1

1

7

High-throughput

0.479

High

1151081

PCH2
Pachytene checkpoint protein 2 homolog

1

1

High-throughput

0.479

High

1161678

IF16
Gamma-interferon-inducible protein 16

1

3

High-throughput

0.479

High

1290735

ZCH18
Zinc finger CCCH domain-containing protein 18

1

1

High-throughput

0.479

High

1367307

ESR2
Estrogen receptor beta

1

3

High-throughput

0.479

High

1437153

UBP36
Ubiquitin carboxyl-terminal hydrolase 36

1

1

High-throughput

0.479

High

1437156

ZRAN1
Ubiquitin thioesterase ZRANB1

1

2

High-throughput

0.479

High

1130460

RRP1B
Ribosomal RNA processing protein 1 homolog B

1

4

High-throughput

0.445

High

386490

SPTA1
Spectrin alpha chain, erythrocytic 1

1

3

High-throughput

0.437

High

1437157

HECD1
E3 ubiquitin-protein ligase HECTD1

1

1

High-throughput

0.437

High

430374

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

948589

APC15
Anaphase-promoting complex subunit 15

1

0

High-throughput

0.279

Low

1437154

SUCO
SUN domain-containing ossification factor

1

0

High-throughput

0.279

Low

619112

PLCG1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1

1

0

High-throughput

0.249

Low

1212989

CF118
Uncharacterized protein C6orf118

1

0

High-throughput

0.249

Low

1332315

TMM75
Putative protein encoded by LINC02912

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025