Protein: JHD1
Putative JmjC domain-containing histone demethylation protein 1 (EC 1.14.11.27) (Heterochromatin-destabilizing protein epe1) ([Histone-H3]-lysine-36 demethylase 1)

Gene: JHD1
Organism: Schizosaccharomyces pombe 972h-
Interactions: 163
UniProt ID: O94603

Gene Ontology (top 5):
GO:0000792 - heterochromatin
GO:0003712 - transcription coregulator activity
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II
GO:0010964 - regulation of regulatory ncRNA-mediated heterochromatin formation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

293751

SWI6
Chromatin-associated protein swi6

5

12

Small-scale

0.722

High

293767

PHF1
SWM histone demethylase complex subunit phf1

1

0

High-throughput

0.586

High

293802

CDT2
Cell division cycle protein cdt2

1

6

Small-scale

0.573

High

194883

CHP2
Chromo domain-containing protein 2

1

9

Small-scale

0.561

High

224176

TAF10
Transcription initiation factor TFIID subunit 10

2

0

Small-scale

0.559

High

251528

TAF6
Transcription initiation factor TFIID subunit 6

2

0

Small-scale

0.559

High

251672

SNF1
SNF1-like protein kinase ssp2

2

0

Small-scale

0.559

High

293809

YK82
Bromodomain-containing protein C631.02

1

11

High-throughput

0.552

High

140395

TAF5
Transcription initiation factor TFIID subunit 5

1

6

Small-scale

0.479

High

143582

SPT5
Transcription elongation factor spt5

1

6

High-throughput

0.479

High

143594

AP3B
AP-3 complex subunit beta

1

1

High-throughput

0.479

High

144298

RPA49
DNA-directed RNA polymerase I subunit rpa49

1

3

High-throughput

0.479

High

145112

MTR4
ATP-dependent RNA helicase mtr4

1

3

High-throughput

0.479

High

194924

DHX15
Probable pre-mRNA-splicing factor ATP-dependent RNA helicase prp43

1

4

High-throughput

0.479

High

195136

BTAF1
TATA-binding protein-associated factor mot1

1

1

High-throughput

0.479

High

223687

CASP
Protein CASP

1

2

High-throughput

0.479

High

223987

FKH2
Fork head protein homolog 2

1

4

High-throughput

0.479

High

224203

RFC1
Replication factor C subunit 1

1

1

High-throughput

0.479

High

292869

CSK2C
Casein kinase II subunit beta-2

1

3

High-throughput

0.479

High

293738

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

1

High-throughput

0.479

High

293740

RPC1
DNA-directed RNA polymerase III subunit rpc1

1

3

High-throughput

0.479

High

293744

RPA1
DNA-directed RNA polymerase I subunit rpa1

1

3

High-throughput

0.479

High

293748

RPB1
DNA-directed RNA polymerase II subunit rpb1

1

3

High-throughput

0.479

High

293750

CSK2A
Casein kinase II subunit alpha

1

8

High-throughput

0.479

High

293752

XRN1
5'-3' exoribonuclease 1

1

1

High-throughput

0.479

High

293753

XRN2
5'-3' exoribonuclease 2

1

1

High-throughput

0.479

High

293754

SMC4
Structural maintenance of chromosomes protein 4

1

1

High-throughput

0.479

High

293757

H2AZ
Histone H2A.Z

1

1

High-throughput

0.479

High

293761

CLR3
Histone deacetylase clr3

1

1

High-throughput

0.479

High

293765

SPT7
Transcriptional activator spt7

1

15

Small-scale

0.479

High

293769

CLF1
Pre-mRNA-splicing factor cwf4

1

3

High-throughput

0.479

High

293770

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

2

High-throughput

0.479

High

293775

DBP10
ATP-dependent RNA helicase dbp10

1

4

High-throughput

0.479

High

293776

UBP8
Probable ubiquitin carboxyl-terminal hydrolase 8

1

1

Small-scale

0.479

High

293777

DBP5
ATP-dependent RNA helicase dbp5

1

2

High-throughput

0.479

High

293785

DRS1
ATP-dependent RNA helicase drs1

1

4

High-throughput

0.479

High

293788

HAS1
ATP-dependent RNA helicase has1

1

3

High-throughput

0.479

High

293789

FAL1
ATP-dependent RNA helicase fal1

1

1

High-throughput

0.479

High

293794

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

2

High-throughput

0.479

High

293800

YDE1
Probable ubiquitin fusion degradation protein C12B10.01c

1

6

High-throughput

0.479

High

293801

GSK3
Protein kinase gsk3

1

1

High-throughput

0.479

High

293804

RFA2
Replication factor A protein 2

1

1

High-throughput

0.479

High

293805

RIF1
Telomere length regulator protein rif1

1

1

High-throughput

0.479

High

293806

YK16
Putative ATP-dependent RNA helicase PB1A10.06c

1

3

High-throughput

0.479

High

293807

TRA1
Transcription-associated protein 1

1

1

Small-scale

0.479

High

293808

YO48
Putative nucleosome assembly protein C36B7.08c

1

1

High-throughput

0.479

High

293811

PRP16
Pre-mRNA-splicing factor ATP-dependent RNA helicase prp16

1

4

High-throughput

0.479

High

293812

YKU5
Uncharacterized WD repeat-containing protein C2E1P5.05

1

6

High-throughput

0.479

High

293813

GAD8
Serine/threonine-protein kinase gad8

1

1

High-throughput

0.479

High

293814

SYF1
Pre-mRNA-splicing factor cwf3

1

2

High-throughput

0.479

High

293818

RPA2
Probable DNA-directed RNA polymerase I subunit RPA2

1

2

High-throughput

0.479

High

293830

BRR2
Pre-mRNA-splicing factor brr2

1

5

High-throughput

0.479

High

293834

DBP4
ATP-dependent RNA helicase dbp4

1

4

High-throughput

0.479

High

293836

UBP71
Ubiquitin carboxyl-terminal hydrolase 15

1

2

High-throughput

0.479

High

293837

RSE1
Pre-mRNA-splicing factor prp12

1

1

High-throughput

0.479

High

293841

GCN5
Histone acetyltransferase gcn5

1

10

Small-scale

0.479

High

293843

BDF1
SWR1 complex bromodomain subunit bdf1

1

11

High-throughput

0.479

High

142697

TAF12
Transcription initiation factor TFIID subunit 12

1

0

Small-scale

0.458

High

142859

GCH1
GTP cyclohydrolase 1

1

0

High-throughput

0.458

High

143496

SA114
Pre-mRNA-splicing factor sap114

1

0

High-throughput

0.458

High

144021

YEG9
Uncharacterized oxidoreductase C26H5.09c

1

0

High-throughput

0.458

High

144032

OLA1
Obg-like ATPase 1

1

0

High-throughput

0.458

High

144042

RFC3
Replication factor C subunit 3

1

0

High-throughput

0.458

High

144522

ELF1
mRNA export factor elf1

1

0

High-throughput

0.458

High

144905

SPT20
SAGA complex subunit spt20

1

0

Small-scale

0.458

High

145928

SSR2
SWI/SNF and RSC complexes subunit ssr2

1

0

High-throughput

0.458

High

223501

SAP61
Pre-mRNA-splicing factor sap61

1

0

High-throughput

0.458

High

223706

SLT11
Pre-mRNA-splicing factor cwf5

1

0

High-throughput

0.458

High

223889

SPT8
Transcription factor spt8

1

0

Small-scale

0.458

High

251415

YJL2
Uncharacterized protein C14G10.02

1

0

High-throughput

0.458

High

251421

YJL4
Uncharacterized protein C14G10.04

1

0

High-throughput

0.458

High

251600

LSM7
U6 snRNA-associated Sm-like protein LSm7

1

0

High-throughput

0.458

High

251619

EKC1
Extragenic suppressor of kinetochore protein 1

1

0

High-throughput

0.458

High

252185

CAF1
Poly(A) ribonuclease pop2

1

0

High-throughput

0.458

High

252318

RRP45
Exosome complex component rrp45

1

0

High-throughput

0.458

High

252633

COG4
Conserved oligomeric Golgi complex subunit 4

1

0

High-throughput

0.458

High

292903

HFI1
Transcriptional coactivator hfi1

1

0

Small-scale

0.458

High

293399

YFE9
Uncharacterized exonuclease C637.09

1

0

High-throughput

0.458

High

293451

PUF3
mRNA-binding protein puf3

1

0

High-throughput

0.458

High

293739

SIR2
NAD-dependent histone deacetylase sir2

1

0

High-throughput

0.458

High

293742

RPA12
DNA-directed RNA polymerase I subunit RPA12

1

0

High-throughput

0.458

High

293743

TOP1
DNA topoisomerase 1

1

0

High-throughput

0.458

High

293745

DBP2
ATP-dependent RNA helicase dbp2

1

0

High-throughput

0.458

High

293746

SPI1
GTP-binding nuclear protein spi1

1

0

High-throughput

0.458

High

293747

MCM3
DNA replication licensing factor mcm3

1

0

High-throughput

0.458

High

293749

U2AF2
Splicing factor U2AF 59 kDa subunit

1

0

High-throughput

0.458

High

293755

RNA1
Ran GTPase-activating protein 1

1

0

High-throughput

0.458

High

293756

RES2
Cell division cycle-related protein res2/pct1

1

0

High-throughput

0.458

High

293760

IF2B
Probable eukaryotic translation initiation factor 2 subunit beta

1

0

High-throughput

0.458

High

293762

YGNB
Putative nucleosome assembly protein C2D10.11C

1

0

High-throughput

0.458

High

293764

NACA
Nascent polypeptide-associated complex subunit alpha

1

0

High-throughput

0.458

High

293768

RIX1
Pre-rRNA-processing protein rix1

1

0

High-throughput

0.458

High

293772

RNP24
RNA-binding protein rnp24

1

0

High-throughput

0.458

High

293773

CDB4
Curved DNA-binding protein

1

0

High-throughput

0.458

High

293774

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

0

High-throughput

0.458

High

293778

FIP1X
Pre-mRNA polyadenylation factor fip1

1

0

High-throughput

0.458

High

293779

SDS23
Protein sds23/moc1

1

0

High-throughput

0.458

High

293783

PRP45
Pre-mRNA-processing protein 45

1

0

High-throughput

0.458

High

293786

PSI1
Protein psi1

1

0

High-throughput

0.458

High

293787

SPT6
Transcription elongation factor spt6

1

0

High-throughput

0.458

High

293790

RRP6
Exosome complex exonuclease rrp6

1

0

High-throughput

0.458

High

293793

PTA1
mRNA cleavage and polyadenylation specificity factor complex subunit pta1

1

0

High-throughput

0.458

High

293795

PAC2
cAMP-independent regulatory protein pac2

1

0

High-throughput

0.458

High

293797

EXO70
Exocyst complex component exo70

1

0

High-throughput

0.458

High

293798

SDA1
Protein sda1

1

0

High-throughput

0.458

High

293803

NACB
Nascent polypeptide-associated complex subunit beta

1

0

High-throughput

0.458

High

293815

YIFC
PDZ domain-containing protein C23G3.12c

1

0

High-throughput

0.458

High

293816

TAF4
Transcription initiation factor TFIID subunit 4

1

0

High-throughput

0.458

High

293819

YJU3
Uncharacterized protein P25A2.03

1

0

High-throughput

0.458

High

293821

MU190
Meiotically up-regulated gene 190 protein

1

0

High-throughput

0.458

High

293825

NGG1
Chromatin-remodeling complexes subunit ngg1

1

0

Small-scale

0.458

High

293826

SGF29
SAGA-associated factor 29

1

0

Small-scale

0.458

High

293827

RU2A
U2 small nuclear ribonucleoprotein A'

1

0

High-throughput

0.458

High

293828

RPA34
DNA-directed RNA polymerase I subunit rpa34

1

0

High-throughput

0.458

High

293829

2AAA
Protein phosphatase PP2A regulatory subunit A

1

0

High-throughput

0.458

High

293831

SEB1
Rpb7-binding protein seb1

1

0

High-throughput

0.458

High

293832

MKT1
Post-transcriptional regulator mkt1

1

0

High-throughput

0.458

High

293833

SNF21
Chromatin structure-remodeling complex subunit snf21

1

0

High-throughput

0.458

High

293835

ARP9
SWI/SNF and RSC complexes subunit arp9

1

0

High-throughput

0.458

High

293839

CDC73
Cell division control protein 73

1

0

High-throughput

0.458

High

293840

SA145
Pre-mRNA-splicing factor sap145

1

0

High-throughput

0.458

High

293842

SWI1
Mating-type switching protein swi1

1

0

High-throughput

0.458

High

293845

SND1
Staphylococcal nuclease domain-containing protein 1

1

0

High-throughput

0.458

High

143419

YEX2
Uncharacterized WD repeat-containing protein C1A6.02

1

7

High-throughput

0.437

High

195213

AP1B1
AP-1 complex subunit beta-1

1

1

High-throughput

0.437

High

223956

YG65
Uncharacterized helicase C15C4.05

1

1

High-throughput

0.437

High

251746

POB1
Protein pob1

1

1

High-throughput

0.437

High

251756

SNU13
13 kDa ribonucleoprotein-associated protein

1

1

High-throughput

0.437

High

252612

PRP39
Pre-mRNA-processing factor 39

1

3

High-throughput

0.437

High

293771

PRH1
Probable ATP-dependent RNA helicase prh1

1

4

High-throughput

0.437

High

293784

SID2
Serine/threonine-protein kinase sid2

1

3

High-throughput

0.437

High

293792

DBP3
ATP-dependent RNA helicase dbp3

1

1

High-throughput

0.437

High

293799

SCK2
Serine/threonine-protein kinase sck2

1

1

High-throughput

0.437

High

293817

YIW2
Uncharacterized helicase C694.02

1

4

High-throughput

0.437

High

142972

RCQ1
Ribosome quality control complex subunit 1

1

0

High-throughput

0.249

Low

143284

YE0C
Uncharacterized FAD-binding protein C17H9.12c

1

0

High-throughput

0.249

Low

143476

EDC4L
Enhancer of mRNA-decapping protein 4-like protein pdc1

1

0

High-throughput

0.249

Low

144954

SPP42
Pre-mRNA-splicing factor spp42

1

0

High-throughput

0.249

Low

145202

TR120
Transport protein particle subunit trs120

1

0

High-throughput

0.249

Low

145570

SCE3
Probable RNA-binding protein sce3

1

0

High-throughput

0.249

Low

251497

STS5
Protein sts5

1

0

High-throughput

0.249

Low

251580

ATPO
ATP synthase subunit 5, mitochondrial

1

0

High-throughput

0.249

Low

251952

ALY2
Putative arrestin-related trafficking adapter C2D10.04

1

0

High-throughput

0.249

Low

293333

MUG87
Meiotically up-regulated gene 87 protein

1

0

High-throughput

0.249

Low

293521

CWF11
Pre-mRNA-splicing factor cwf11

1

0

High-throughput

0.249

Low

293607

PAM17
Presequence translocated-associated motor subunit pam17, mitochondrial

1

0

High-throughput

0.249

Low

293741

AP3M
AP-3 complex subunit mu

1

0

High-throughput

0.249

Low

293758

STE20
Serine/threonine-protein kinase shk1/pak1

1

0

High-throughput

0.249

Low

293759

EI2BE
Translation initiation factor eIF2B subunit epsilon

1

0

High-throughput

0.249

Low

293763

EIF3J
Probable eukaryotic translation initiation factor 3 subunit J

1

0

High-throughput

0.249

Low

293766

YB0G
Probable ADP-ribosylation factor-binding protein C25H2.16c

1

0

High-throughput

0.249

Low

293780

YAG1
Uncharacterized WD repeat-containing protein C12G12.01c

1

0

High-throughput

0.249

Low

293781

RCL1
Probable RNA 3'-terminal phosphate cyclase-like protein

1

0

High-throughput

0.249

Low

293782

YAG7
Uncharacterized protein C12G12.07c

1

0

High-throughput

0.249

Low

293791

FKBPH
Probable peptidyl-prolyl cis-trans isomerase C27F1.06c

1

0

High-throughput

0.249

Low

293796

PEX11
Peroxisomal biogenesis factor 11

1

0

High-throughput

0.249

Low

293810

YLI2
Uncharacterized protein C458.02c

1

0

High-throughput

0.249

Low

293820

YIE2
SH3 domain-containing protein PJ696.02

1

0

High-throughput

0.249

Low

293822

RQC2
Ribosome quality control complex subunit 2

1

0

High-throughput

0.249

Low

293823

EI2BA
Translation initiation factor eIF2B subunit alpha

1

0

High-throughput

0.249

Low

293824

STT4
Phosphatidylinositol 4-kinase stt4

1

0

High-throughput

0.249

Low

293838

AP1G1
AP-1 complex subunit gamma-1

1

0

High-throughput

0.249

Low

293844

YCJE
Uncharacterized protein C63.14

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024