Protein: PSN
Presenilin homolog (DmPS) (EC 3.4.23.-) (dPS)

Gene: PSN
Organism: Drosophila melanogaster
Interactions: 16
UniProt ID: O02194

Gene Ontology (top 5):
GO:0000139 - Golgi membrane
GO:0004175 - endopeptidase activity
GO:0005789 - endoplasmic reticulum membrane
GO:0006508 - proteolysis
GO:0006509 - membrane protein ectodomain proteolysis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

145758

PSN
Presenilin homolog

2

7

Small-scale

0.799

High

145769

APH1
Gamma-secretase subunit Aph-1

2

10

Small-scale

0.754

High

145760

PEN2
Gamma-secretase subunit pen-2

1

5

Small-scale

0.618

High

145759

NOTCH
Neurogenic locus Notch protein [Cleaved into: Processed neurogenic locus Notch protein]

2

11

Small-scale

0.552

High

145766

FLNA
Filamin-A

2

5

Small-scale

0.535

High

145770

Q9VWD9
Ubiquilin-like protein

1

4

Small-scale

0.437

High

145771

Q9VZU6
BTB-VII protein domain

1

1

High-throughput

0.417

High

145764

NICA
Nicastrin

1

6

High-throughput

0.381

High

145761

MET2
tRNA N(3)-methylcytidine methyltransferase Mettl2

2

0

Small-scale

0.306

High

56081

A1Z9U0
FI03313p

1

0

High-throughput

0.265

Low

145762

Q8IMI5
FI04474p

1

0

Small-scale

0.249

Low

145763

Q8MRA3
Hibris, isoform A

1

0

Small-scale

0.249

Low

145767

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

0

High-throughput

0.249

Low

145768

ZUC
Mitochondrial cardiolipin hydrolase

1

0

High-throughput

0.249

Low

145765

Q9VEL7
Beaten path IIb, isoform A

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025