Protein: FYN
Tyrosine-protein kinase Fyn (EC 2.7.10.2) (Proto-oncogene c-Fyn) (p59-Fyn)

Gene: FYN
Organism: Mus musculus
Interactions: 54
UniProt ID: P39688

Gene Ontology (top 5):
GO:0000304 - response to singlet oxygen
GO:0001664 - G protein-coupled receptor binding
GO:0001764 - neuron migration
GO:0002250 - adaptive immune response
GO:0003015 - heart process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

611446

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

2

20

Small-scale

0.754

High

686941

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

2

20

Small-scale

0.754

High

757443

FAK1
Focal adhesion kinase 1

2

20

Small-scale

0.743

High

813523

BCAR1
Breast cancer anti-estrogen resistance protein 1

2

20

Small-scale

0.743

High

313105

SH21A
SH2 domain-containing protein 1A

2

19

Small-scale

0.737

High

651485

CBL
E3 ubiquitin-protein ligase CBL

6

20

Small-scale

0.722

High

813508

PTN5
Tyrosine-protein phosphatase non-receptor type 5

2

20

Small-scale

0.721

High

813512

EPHA4
Ephrin type-A receptor 4

1

19

Small-scale

0.692

High

813520

KHDR1
KH domain-containing, RNA-binding, signal transduction-associated protein 1

4

20

Small-scale

0.688

High

813534

SLAF1
Signaling lymphocytic activation molecule

3

17

Small-scale

0.684

High

59107

PTPRF
Receptor-type tyrosine-protein phosphatase F

1

20

Small-scale

0.648

High

813516

PHAG1
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1

1

11

High-throughput

0.646

High

205167

FYB1
FYN-binding protein 1

1

16

Small-scale

0.618

High

483860

CSF1R
Macrophage colony-stimulating factor 1 receptor

1

20

Small-scale

0.618

High

813505

CDK5
Cyclin-dependent kinase 5

1

14

Small-scale

0.618

High

813506

HCLS1
Hematopoietic lineage cell-specific protein

1

20

Small-scale

0.618

High

813517

SKAP2
Src kinase-associated phosphoprotein 2

1

20

Small-scale

0.618

High

813518

SH21C
SH2 domain-containing protein 1B2

1

20

Small-scale

0.618

High

813519

GRB2
Growth factor receptor-bound protein 2

1

20

Small-scale

0.618

High

813524

RHG33
Rho GTPase-activating protein 33

1

20

Small-scale

0.618

High

813526

PLCG2
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2

1

17

Small-scale

0.618

High

813527

Q91YX7
Ras GTPase-activating protein 1

1

20

Small-scale

0.618

High

813529

NCK1
SH2/SH3 adapter protein Nck1

1

20

Small-scale

0.618

High

813537

CLNK
Cytokine-dependent hematopoietic cell linker

1

20

Small-scale

0.618

High

813525

Q8C2G0
Protein-tyrosine kinase 2-beta

1

20

High-throughput

0.590

High

431951

PGFRB
Platelet-derived growth factor receptor beta

1

20

Small-scale

0.575

High

591104

MET
Hepatocyte growth factor receptor

1

20

High-throughput

0.575

High

813521

LCP2
Lymphocyte cytosolic protein 2

1

20

High-throughput

0.575

High

813509

WASP
Actin nucleation-promoting factor WAS

1

20

Small-scale

0.561

High

312330

ZN106
Zinc finger protein 106

1

0

Small-scale

0.537

High

813532

SPHK2
Sphingosine kinase 2

1

3

Small-scale

0.527

High

602914

ENOA
Alpha-enolase

1

4

Small-scale

0.501

High

813510

DAB1
Disabled homolog 1

1

17

Small-scale

0.501

High

813513

ENAH
Protein enabled homolog

1

19

Small-scale

0.501

High

813514

FMN1
Formin-1

1

17

Small-scale

0.501

High

813515

CD36
Platelet glycoprotein 4

1

4

Small-scale

0.501

High

108502

G3X9H5
Huntingtin

1

4

High-throughput

0.479

High

148356

DIAP1
Protein diaphanous homolog 1

1

14

Small-scale

0.479

High

236330

NKG2D
NKG2-D type II integral membrane protein

1

4

Small-scale

0.479

High

723282

SSR3
Somatostatin receptor type 3

1

10

High-throughput

0.479

High

771409

NMDE1
Glutamate receptor ionotropic, NMDA 2A

1

12

Small-scale

0.479

High

813511

NMDE2
Glutamate receptor ionotropic, NMDA 2B

1

12

Small-scale

0.479

High

813528

MED28
Mediator of RNA polymerase II transcription subunit 28

1

8

Small-scale

0.479

High

813538

KHDR2
KH domain-containing, RNA-binding, signal transduction-associated protein 2

1

20

Small-scale

0.479

High

813533

TMM47
Transmembrane protein 47

1

0

Small-scale

0.458

High

813507

DYLT1
Dynein light chain Tctex-type 1

1

2

High-throughput

0.457

High

813531

RAVR1
Ribonucleoprotein PTB-binding 1

1

5

High-throughput

0.457

High

236812

LAT
Linker for activation of T-cells family member 1

1

4

High-throughput

0.445

High

486743

CTLA4
Cytotoxic T-lymphocyte protein 4

1

3

Small-scale

0.445

High

813522

NCOA2
Nuclear receptor coactivator 2

1

7

Small-scale

0.445

High

813535

SRCN1
SRC kinase signaling inhibitor 1

1

7

High-throughput

0.445

High

813536

ADDB
Beta-adducin

1

5

Small-scale

0.445

High

813530

UCK2
Uridine-cytidine kinase 2

1

0

High-throughput

0.438

High

630393

TNR9
Tumor necrosis factor receptor superfamily member 9

1

11

Small-scale

0.437

High


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Last updated: 11Aug2025