HitPredict - High confidence protein-protein interactions

Protein: M3K4
Mitogen-activated protein kinase kinase kinase 4 (EC 2.7.11.25) (MAPK/ERK kinase kinase 4) (MEK kinase 4) (MEKK 4)

Gene: M3K4, Map3k4
Organism: Mus musculus
Interactions: 6
UniProt ID: O08648

Gene Ontology (top 5):
GO:0001890 - placenta development
GO:0004672 - protein kinase activity
GO:0004709 - MAP kinase kinase kinase activity
GO:0005524 - ATP binding
GO:0005737 - cytoplasm

Download interactions: TXT MITAB-2.5

Interaction	Interactor	Experiments	Homologs	Category	Interaction Score	Confidence
148036	AXIN1 Axin-1	2	8	Small-scale	0.806	High
148039	GSK3B Glycogen synthase kinase-3 beta	1	17	Small-scale	0.665	High
148035	M3K4 Mitogen-activated protein kinase kinase kinase 4	1	14	Small-scale	0.618	High
148037	TRAF4 TNF receptor-associated factor 4	1	15	Small-scale	0.479	High
148038	WDTC1 WD and tetratricopeptide repeats protein 1	1	12	High-throughput	0.437	High

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Last updated: 11Aug2025