Protein: SIAH2
E3 ubiquitin-protein ligase SIAH2 (EC 2.3.2.27) (RING-type E3 ubiquitin transferase SIAH2) (Seven in absentia homolog 2) (Siah-2) (mSiah2)

Gene: SIAH2
Organism: Mus musculus
Interactions: 11
UniProt ID: Q06986

Gene Ontology (top 5):
GO:0004842 - ubiquitin-protein transferase activity
GO:0005654 - nucleoplasm
GO:0005769 - early endosome
GO:0005829 - cytosol
GO:0006511 - ubiquitin-dependent protein catabolic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

148117

AKAP1
A-kinase anchor protein 1, mitochondrial

1

1

Small-scale

0.581

High

1057500

Q8BK32
Nuclear receptor co-repressor 1

2

3

Small-scale

0.533

High

789691

PPARG
Peroxisome proliferator-activated receptor gamma

1

6

Small-scale

0.479

High

789725

THB
Thyroid hormone receptor beta

1

7

Small-scale

0.479

High

989504

THA
Thyroid hormone receptor alpha

1

7

Small-scale

0.479

High

1057502

PLCE1
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1

1

2

Small-scale

0.479

High

1057503

SPY2
Protein sprouty homolog 2

1

5

Small-scale

0.479

High

1057504

SPY1
Protein sprouty homolog 1

1

5

Small-scale

0.479

High

1057499

SH3R1
E3 ubiquitin-protein ligase SH3RF1

1

13

Small-scale

0.457

High

1057501

SENP7
Sentrin-specific protease 7

1

1

Small-scale

0.437

High

1057505

SPY4
Protein sprouty homolog 4

1

5

Small-scale

0.437

High


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Last updated: 11Aug2025