HitPredict
Protein: SPY4
Protein sprouty homolog 4 (Spry-4)

Gene: SPY4, Spry4
Organism: Mus musculus
Interactions: 8
UniProt ID: Q9WTP2

Gene Ontology (top 5):
GO:0004860 - protein kinase inhibitor activity
GO:0005737 - cytoplasm
GO:0009966 - regulation of signal transduction
GO:0032587 - ruffle membrane
GO:1900025 - negative regulation of substrate adhesion-dependent cell spreading

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score		 Confidence

1221264

 GRB2
Growth factor receptor-bound protein 2

1

15

Small-scale

 0.515

High

1455885

 SPY2
Protein sprouty homolog 2

1

15

Small-scale

 0.515

High

1490128

 SPY4
Protein sprouty homolog 4

1

14

Small-scale

 0.515

High

1190922

 SPRY3
Protein sprouty homolog 3

1

15

Small-scale

 0.479

High

1223930

 SOS1
Son of sevenless homolog 1

1

5

Small-scale

 0.470

High

1455888

 SPY1
Protein sprouty homolog 1

1

15

Small-scale

 0.470

High

1057505

 SIAH2
E3 ubiquitin-protein ligase SIAH2

1

5

Small-scale

 0.437

High

Service provided by Combinatics, Japan

Last updated: 11Aug2025