Protein: TSR1
Ribosome biogenesis protein TSR1 (20S rRNA accumulation protein 1)

Gene: TSR1
Organism: Saccharomyces cerevisiae S288C
Interactions: 130
UniProt ID: Q07381

Gene Ontology (top 5):
GO:0000461 - endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0000479 - endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003924 - GTPase activity
GO:0005525 - GTP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

770069

RIO2
Serine/threonine-protein kinase RIO2

15

4

Small-scale

0.981

High

709386

LTV1
Protein LTV1

7

0

Small-scale

0.907

High

748718

ENP1
Essential nuclear protein 1

17

2

Small-scale

0.762

High

991192

NOB1
20S-pre-rRNA D-site endonuclease NOB1

8

1

Small-scale

0.749

High

784529

DIM1
Dimethyladenosine transferase

8

1

Small-scale

0.747

High

991199

RRP12
Ribosomal RNA-processing protein 12

6

2

Small-scale

0.732

High

991204

PNO1
Pre-rRNA-processing protein PNO1

6

2

Small-scale

0.729

High

664550

HRR25
Casein kinase I homolog HRR25

5

4

Small-scale

0.718

High

860535

SLX9
Ribosome biogenesis protein SLX9

6

0

Small-scale

0.699

High

407593

RS9B
Small ribosomal subunit protein uS4B

3

4

High-throughput

0.662

High

408147

RS13
Small ribosomal subunit protein uS15

3

3

High-throughput

0.656

High

645677

RS7A
Small ribosomal subunit protein eS7A

3

3

High-throughput

0.656

High

480338

RS6A
Small ribosomal subunit protein eS6A

3

3

High-throughput

0.640

High

480908

RS8A
Small ribosomal subunit protein eS8A

3

2

Small-scale

0.640

High

492581

HSP71
Heat shock protein SSA1

3

2

High-throughput

0.633

High

991194

BMS1
Ribosome biogenesis protein BMS1

1

1

High-throughput

0.618

High

479537

RS24A
Small ribosomal subunit protein eS24A

2

2

High-throughput

0.611

High

613759

RS3A2
Small ribosomal subunit protein eS1B

2

5

High-throughput

0.611

High

644951

RS5
Small ribosomal subunit protein uS7

2

1

High-throughput

0.611

High

416088

DED1
ATP-dependent RNA helicase DED1

2

2

Small-scale

0.601

High

358280

RS17A
Small ribosomal subunit protein eS17A

3

3

High-throughput

0.599

High

991205

HRP1
Nuclear polyadenylated RNA-binding protein 4

2

1

High-throughput

0.588

High

141545

RS9A
Small ribosomal subunit protein uS4A

2

4

High-throughput

0.584

High

376943

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

2

1

High-throughput

0.584

High

407349

RS3
Small ribosomal subunit protein uS3

2

3

High-throughput

0.584

High

413729

RS14A
Small ribosomal subunit protein uS11A

2

4

High-throughput

0.584

High

479830

RS4A
Small ribosomal subunit protein eS4A

2

1

High-throughput

0.584

High

482481

RS18A
Small ribosomal subunit protein uS13A

2

2

High-throughput

0.584

High

535131

RL3
Large ribosomal subunit protein uL3

2

2

Small-scale

0.584

High

632112

RS2
Small ribosomal subunit protein uS5

2

3

High-throughput

0.584

High

700649

RSSA1
Small ribosomal subunit protein uS2A

2

6

High-throughput

0.584

High

706512

RS3A1
Small ribosomal subunit protein eS1A

2

5

High-throughput

0.584

High

743019

GBLP
Small ribosomal subunit protein RACK1

2

6

High-throughput

0.584

High

752694

RS20
Small ribosomal subunit protein uS10

2

2

High-throughput

0.584

High

820197

RS12
Small ribosomal subunit protein eS12

2

1

High-throughput

0.584

High

967784

RS15
Small ribosomal subunit protein uS19

2

2

High-throughput

0.584

High

991198

RIO1
Serine/threonine-protein kinase RIO1

2

4

High-throughput

0.584

High

426175

RS19A
Small ribosomal subunit protein eS19A

3

4

High-throughput

0.578

High

759459

STM1
Suppressor protein STM1

2

0

High-throughput

0.576

High

710521

PP2C3
Protein phosphatase 2C homolog 3

2

0

High-throughput

0.563

High

864547

TR112
Multifunctional methyltransferase subunit TRM112

2

0

Small-scale

0.559

High

471278

RS22A
Small ribosomal subunit protein uS8A

2

3

High-throughput

0.558

High

535285

RS17B
Small ribosomal subunit protein eS17B

2

3

High-throughput

0.558

High

512904

SSB1
Ribosome-associated molecular chaperone SSB1

2

3

High-throughput

0.552

High

765261

RS26B
Small ribosomal subunit protein eS26B

2

1

High-throughput

0.549

High

355665

H2B1
Histone H2B.1

1

4

High-throughput

0.536

High

676408

XPO1
Exportin-1

1

1

High-throughput

0.536

High

976870

HAS1
ATP-dependent RNA helicase HAS1

1

6

High-throughput

0.536

High

991190

NOP6
Nucleolar protein 6

1

1

High-throughput

0.536

High

991191

NOP12
Nucleolar protein 12

1

1

High-throughput

0.536

High

991203

NOP14
Nucleolar complex protein 14

1

2

High-throughput

0.536

High

549512

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

3

High-throughput

0.515

High

615186

BUR1
Serine/threonine-protein kinase BUR1

1

2

High-throughput

0.515

High

740869

YC16
UPF0743 protein YCR087C-A

1

1

High-throughput

0.515

High

774624

PRK1
Actin-regulating kinase PRK1

1

2

High-throughput

0.515

High

860753

UTP22
U3 small nucleolar RNA-associated protein 22

1

1

High-throughput

0.515

High

864742

ESF2
Pre-rRNA-processing protein ESF2

1

2

High-throughput

0.515

High

979249

UTP15
U3 small nucleolar RNA-associated protein 15

1

5

High-throughput

0.515

High

991195

NOP53
Ribosome biogenesis protein NOP53

1

1

High-throughput

0.515

High

991197

YRA1
RNA annealing protein YRA1

1

2

High-throughput

0.515

High

350823

RAS2
Ras-like protein 2

1

0

High-throughput

0.513

High

425390

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.513

High

650403

SPT5
Transcription elongation factor SPT5

1

0

Small-scale

0.513

High

728325

DEF1
RNA polymerase II degradation factor 1

1

0

Small-scale

0.513

High

760597

SSN3
Meiotic mRNA stability protein kinase SSN3

1

0

High-throughput

0.513

High

765073

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

0

Small-scale

0.513

High

766711

NUG1
Nuclear GTP-binding protein NUG1

1

0

High-throughput

0.513

High

981830

YM94
Uncharacterized protein YMR315W

1

0

Small-scale

0.513

High

655904

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

1

0

High-throughput

0.493

High

758103

BFR1
Nuclear segregation protein BFR1

1

0

High-throughput

0.493

High

791282

KRI1
Protein KRI1

1

0

High-throughput

0.493

High

988556

TSR2
Pre-rRNA-processing protein TSR2

1

0

High-throughput

0.493

High

408477

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

1

High-throughput

0.479

High

470768

RS21A
Small ribosomal subunit protein eS21A

1

2

High-throughput

0.479

High

481559

RS11B
Small ribosomal subunit protein uS17B

1

1

High-throughput

0.479

High

481827

RS16B
Small ribosomal subunit protein uS9B

1

2

High-throughput

0.479

High

606152

RAD53
Serine/threonine-protein kinase RAD53

1

3

High-throughput

0.479

High

624181

DBP2
ATP-dependent RNA helicase DBP2

1

1

High-throughput

0.479

High

628515

SIS1
Protein SIS1

1

4

High-throughput

0.479

High

634790

KRR1
KRR1 small subunit processome component

1

2

High-throughput

0.479

High

635162

YCQ6
Uncharacterized protein YCR016W

1

1

High-throughput

0.479

High

635443

BUD23
18S rRNA

1

1

High-throughput

0.479

High

648443

NSR1
Nuclear localization sequence-binding protein

1

1

High-throughput

0.479

High

663450

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

665078

BMH1
Protein BMH1

1

1

High-throughput

0.479

High

687489

EF2
Elongation factor 2

1

1

Small-scale

0.479

High

688449

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

716208

SKI2
Antiviral helicase SKI2

1

3

High-throughput

0.479

High

730141

RS27A
Small ribosomal subunit protein eS27A

1

3

High-throughput

0.479

High

753026

RS27B
Small ribosomal subunit protein eS27B

1

3

High-throughput

0.479

High

761927

RS14B
Small ribosomal subunit protein uS11B

1

4

High-throughput

0.479

High

792598

UTP10
U3 small nucleolar RNA-associated protein 10

1

1

High-throughput

0.479

High

804857

RSSA2
Small ribosomal subunit protein uS2B

1

6

High-throughput

0.479

High

811361

NOP9
Nucleolar protein 9

1

1

Small-scale

0.479

High

816547

RS7B
Small ribosomal subunit protein eS7B

1

3

High-throughput

0.479

High

841444

UBC9
SUMO-conjugating enzyme UBC9

1

3

High-throughput

0.479

High

866508

APJ1
J domain-containing protein APJ1

1

4

High-throughput

0.479

High

965496

NOP3
Serine/arginine

1

5

High-throughput

0.479

High

972638

XRN2
5'-3' exoribonuclease 2

1

1

High-throughput

0.479

High

979044

DHR1
Probable ATP-dependent RNA helicase DHR1

1

2

High-throughput

0.479

High

984217

HRQ1
ATP-dependent helicase HRQ1

1

4

Small-scale

0.479

High

991196

RRP6
Exosome complex exonuclease RRP6

1

2

High-throughput

0.479

High

991200

RS21B
Small ribosomal subunit protein eS21B

1

2

High-throughput

0.479

High

366971

HSP82
ATP-dependent molecular chaperone HSP82

1

0

High-throughput

0.458

High

523313

NAT1
N-terminal acetyltransferase A complex subunit NAT1

1

0

High-throughput

0.458

High

558278

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

600309

DAL82
Protein DAL82

1

0

High-throughput

0.458

High

753551

OTU2
OTU domain-containing protein 2

1

0

High-throughput

0.458

High

987049

TFC6
Transcription factor tau 91 kDa subunit

1

0

High-throughput

0.458

High

450207

HSP73
Heat shock protein SSA3

1

2

High-throughput

0.445

High

633616

MAS5
Mitochondrial protein import protein MAS5

1

4

High-throughput

0.445

High

705712

HSP78
Heat shock protein 78, mitochondrial

1

2

High-throughput

0.445

High

769595

SSB2
Ribosome-associated molecular chaperone SSB2

1

3

High-throughput

0.445

High

383373

RL25
Large ribosomal subunit protein uL23

1

2

High-throughput

0.437

High

405852

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.437

High

426335

RS19B
Small ribosomal subunit protein eS19B

1

4

High-throughput

0.437

High

470691

RS25B
Small ribosomal subunit protein eS25B

1

2

High-throughput

0.437

High

471530

RS28B
Small ribosomal subunit protein eS28B

1

2

High-throughput

0.437

High

472417

RL31A
Large ribosomal subunit protein eL31A

1

3

High-throughput

0.437

High

762599

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

765214

RS26A
Small ribosomal subunit protein eS26A

1

1

High-throughput

0.437

High

780529

RS29A
Small ribosomal subunit protein uS14A

1

1

High-throughput

0.437

High

780555

RS29B
Small ribosomal subunit protein uS14B

1

1

High-throughput

0.437

High

860391

EIF2A
Eukaryotic translation initiation factor 2A

1

1

High-throughput

0.437

High

991193

RS10A
Small ribosomal subunit protein eS10A

1

2

High-throughput

0.437

High

991201

RS25A
Small ribosomal subunit protein eS25A

1

2

High-throughput

0.437

High

991202

RS28A
Small ribosomal subunit protein eS28A

1

2

High-throughput

0.437

High

556324

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

481998

RL12B
Large ribosomal subunit protein uL11B

1

0

High-throughput

0.249

Low

516918

SIR4
Regulatory protein SIR4

1

0

Small-scale

0.249

Low


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Last updated: 15 Jul 2024