HitPredict
Protein: HCD2
3-hydroxyacyl-CoA dehydrogenase type-2 (EC 1.1.1.35) (17-beta-estradiol 17-dehydrogenase) (EC 1.1.1.62) (2-methyl-3-hydroxybutyryl-CoA dehydrogenase) (MHBD) (3-alpha-(17-beta)-hydroxysteroid dehydrogenase (NAD(+))) (EC 1.1.1.239) (3-hydroxy-2-methylbutyryl-CoA dehydrogenase) (EC 1.1.1.178) (3-hydroxyacyl-CoA dehydrogenase type II) (3alpha(or 20beta)-hydroxysteroid dehydrogenase) (EC 1.1.1.53) (7-alpha-hydroxysteroid dehydrogenase) (EC 1.1.1.159) (Endoplasmic reticulum-associated amyloid beta-peptide-binding protein) (Mitochondrial ribonuclease P protein 2) (Mitochondrial RNase P protein 2) (Short chain dehydrogenase/reductase family 5C member 1) (Short-chain type dehydrogenase/reductase XH98G2) (Type II HADH)

Gene: HCD2, Hsd17b10
Organism: Mus musculus
Interactions: 21
UniProt ID: O08756

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0003857 - (3S)-3-hydroxyacyl-CoA dehydrogenase (NAD+) activity
GO:0004303 - estradiol 17-beta-dehydrogenase [NAD(P)+] activity
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score		 Confidence

148229

 ELAV1
ELAV-like protein 1

1

3

High-throughput

 0.445

High

148232

 PRDX2
Peroxiredoxin-2

1

7

High-throughput

 0.445

High

148236

 DNM1L
Dynamin-1-like protein

1

1

High-throughput

 0.445

High

148241

 RHOA
Transforming protein RhoA

1

6

High-throughput

 0.445

High

148221

 MYL1
Myosin light chain 1/3, skeletal muscle isoform

1

1

High-throughput

 0.407

High

148222

 PERI
Peripherin

1

1

High-throughput

 0.407

High

148223

 PPIA
Peptidyl-prolyl cis-trans isomerase A

1

1

High-throughput

 0.407

High

148224

 ENOB
Beta-enolase

1

2

High-throughput

 0.407

High

148225

 PABP1
Polyadenylate-binding protein 1

1

1

High-throughput

 0.407

High

148226

 PRS6B
26S proteasome regulatory subunit 6B

1

4

High-throughput

 0.407

High

148227

 EF2
Elongation factor 2

1

3

High-throughput

 0.407

High

148228

 SF3B6
Splicing factor 3B subunit 6

1

3

High-throughput

 0.407

High

148230

 HNRL2
Heterogeneous nuclear ribonucleoprotein U-like protein 2

1

1

High-throughput

 0.407

High

148233

 TIF1B
Transcription intermediary factor 1-beta

1

4

High-throughput

 0.407

High

148234

 MYO6
Unconventional myosin-VI

1

1

High-throughput

 0.407

High

148235

 NOP58
Nucleolar protein 58

1

2

High-throughput

 0.407

High

148237

 PRP19
Pre-mRNA-processing factor 19

1

2

High-throughput

 0.407

High

148238

 RNPS1
RNA-binding protein with serine-rich domain 1

1

3

High-throughput

 0.407

High

148239

 CHTOP
Chromatin target of PRMT1 protein

1

1

High-throughput

 0.407

High

148240

 DYHC1
Cytoplasmic dynein 1 heavy chain 1

1

2

High-throughput

 0.407

High

148231

 SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

0

High-throughput

 0.232

Low

Service provided by Combinatics, Japan

Last updated: 11Aug2025