Protein: HFI1
Transcriptional coactivator HFI1/ADA1

Gene: HFI1
Organism: Saccharomyces cerevisiae S288C
Interactions: 157
UniProt ID: Q12060

Gene Ontology (top 5):
GO:0000124 - SAGA complex
GO:0003712 - transcription coregulator activity
GO:0003713 - transcription coactivator activity
GO:0005634 - nucleus
GO:0006325 - chromatin organization

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

858582

TAF6
Transcription initiation factor TFIID subunit 6

12

1

Small-scale

0.977

High

977538

TAF12
Transcription initiation factor TFIID subunit 12

12

1

Small-scale

0.974

High

982951

TAF9
Transcription initiation factor TFIID subunit 9

9

1

Small-scale

0.965

High

842086

SPT20
Transcription factor SPT20

14

0

Small-scale

0.933

High

715410

SPT7
Transcriptional activator SPT7

20

3

Small-scale

0.764

High

970414

ADA2
Transcriptional adapter 2

14

2

Small-scale

0.762

High

975991

GCN5
Histone acetyltransferase GCN5

13

1

Small-scale

0.759

High

755470

TRA1
Transcription-associated protein 1

13

2

Small-scale

0.758

High

420628

SPT3
Protein SPT3

12

1

Small-scale

0.757

High

744710

TAF5
Transcription initiation factor TFIID subunit 5

13

1

Small-scale

0.757

High

691350

NGG1
Chromatin-remodeling complexes subunit NGG1

11

1

Small-scale

0.754

High

837477

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

11

1

Small-scale

0.754

High

757481

SPT8
Transcription factor SPT8

9

1

Small-scale

0.753

High

633904

SGF29
SAGA-associated factor 29

7

1

Small-scale

0.746

High

859816

SGF73
SAGA-associated factor 73

8

1

Small-scale

0.745

High

1014889

TAF10
Transcription initiation factor TFIID subunit 10

7

1

Small-scale

0.742

High

974445

SGF11
SAGA-associated factor 11

7

0

Small-scale

0.710

High

1014954

SUS1
Transcription and mRNA export factor SUS1

4

1

Small-scale

0.694

High

492747

HSP71
Heat shock protein SSA1

3

2

Small-scale

0.624

High

527074

TBP
TATA-box-binding protein

2

0

Small-scale

0.585

High

1014949

HFI1
Transcriptional coactivator HFI1/ADA1

2

0

Small-scale

0.585

High

687764

BTAF1
TATA-binding protein-associated factor MOT1

2

1

Small-scale

0.584

High

587891

AP1
AP-1-like transcription factor YAP1

2

0

High-throughput

0.576

High

495235

HSP72
Heat shock protein SSA2

2

2

Small-scale

0.571

High

769735

SSB2
Ribosome-associated molecular chaperone SSB2

2

2

Small-scale

0.571

High

1014950

YRA1
RNA annealing protein YRA1

2

0

Small-scale

0.559

High

707066

MSN4
Zinc finger protein MSN4

2

1

High-throughput

0.552

High

450228

HSP73
Heat shock protein SSA3

1

2

High-throughput

0.536

High

436850

SWI5
Transcriptional factor SWI5

1

0

High-throughput

0.513

High

676452

XPO1
Exportin-1

1

0

High-throughput

0.513

High

686870

MED16
Mediator of RNA polymerase II transcription subunit 16

1

0

High-throughput

0.513

High

859243

MED5
Mediator of RNA polymerase II transcription subunit 5

1

0

High-throughput

0.513

High

985481

ECM22
Sterol regulatory element-binding protein ECM22

1

0

High-throughput

0.513

High

1014951

HAL9
Halotolerance protein 9

1

0

High-throughput

0.513

High

439684

SPS1
Sporulation-specific protein 1

1

0

High-throughput

0.493

High

688839

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

0

High-throughput

0.480

High

693757

IME2
Meiosis induction protein kinase IME2/SME1

1

0

High-throughput

0.480

High

334831

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

2

Small-scale

0.479

High

513102

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

Small-scale

0.479

High

744176

ATR
Serine/threonine-protein kinase MEC1

1

2

Small-scale

0.479

High

751097

RCK1
Serine/threonine-protein kinase RCK1

1

1

High-throughput

0.479

High

407385

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

411108

PDC1
Pyruvate decarboxylase isozyme 1

1

0

Small-scale

0.458

High

454930

CDC16
Anaphase-promoting complex subunit CDC16

1

0

Small-scale

0.458

High

663602

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

689981

ASF1
Histone chaperone ASF1

1

0

Small-scale

0.458

High

691138

HOG1
Mitogen-activated protein kinase HOG1

1

0

Small-scale

0.458

High

694296

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

0

High-throughput

0.458

High

697451

CHD1
Chromo domain-containing protein 1

1

0

Small-scale

0.458

High

716378

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

716523

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

763549

DHE5
NADP-specific glutamate dehydrogenase 2

1

0

Small-scale

0.458

High

810453

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

Small-scale

0.458

High

812148

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

977458

TAF8
Transcription initiation factor TFIID subunit 8

1

0

High-throughput

0.458

High

979485

LCD1
DNA damage checkpoint protein LCD1

1

0

Small-scale

0.458

High

334551

G3P2
Glyceraldehyde-3-phosphate dehydrogenase 2

1

2

High-throughput

0.445

High

648450

NSR1
Nuclear localization sequence-binding protein

1

1

High-throughput

0.445

High

695747

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

707004

MSN2
Zinc finger protein MSN2

1

1

High-throughput

0.445

High

754792

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.445

High

797969

RSC8
Chromatin structure-remodeling complex protein RSC8

1

2

High-throughput

0.445

High

761161

PCF11
Protein PCF11

1

0

High-throughput

0.438

High

423926

ATPA
ATP synthase subunit alpha, mitochondrial

1

1

Small-scale

0.437

High

479640

RS30A
Small ribosomal subunit protein eS30A

1

1

High-throughput

0.437

High

556360

VATB
V-type proton ATPase subunit B

1

1

Small-scale

0.437

High

375632

RPC1
DNA-directed RNA polymerase III subunit RPC1

1

0

High-throughput

0.426

High

419405

HAP2
Transcriptional activator HAP2

1

0

High-throughput

0.426

High

423707

ADR1
Regulatory protein ADR1

1

0

High-throughput

0.426

High

501183

HSF
Heat shock transcription factor

1

0

High-throughput

0.426

High

549080

TRM1
tRNA

1

0

High-throughput

0.426

High

554766

HSP26
Heat shock protein 26

1

0

High-throughput

0.426

High

560820

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.426

High

627702

NAP1
Nucleosome assembly protein

1

0

High-throughput

0.426

High

631691

RPC4
DNA-directed RNA polymerase III subunit RPC4

1

0

High-throughput

0.426

High

650013

BUD14
Bud site selection protein 14

1

0

High-throughput

0.426

High

650412

SPT5
Transcription elongation factor SPT5

1

0

High-throughput

0.426

High

743050

GBLP
Small ribosomal subunit protein RACK1

1

0

High-throughput

0.426

High

860767

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

High-throughput

0.426

High

962008

REG1
Resistance to glucose repression protein 1

1

0

High-throughput

0.426

High

991408

SUB2
ATP-dependent RNA helicase SUB2

1

0

High-throughput

0.426

High

1014952

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.426

High

334997

G3P1
Glyceraldehyde-3-phosphate dehydrogenase 1

1

2

High-throughput

0.407

High

357575

RLA4
Large ribosomal subunit protein P2B

1

1

High-throughput

0.407

High

399936

RLA2
Large ribosomal subunit protein P2A

1

1

High-throughput

0.407

High

416818

CDC31
Cell division control protein 31

1

1

High-throughput

0.407

High

479662

RS30B
Small ribosomal subunit protein eS30B

1

1

High-throughput

0.407

High

540260

PP2B2
Serine/threonine-protein phosphatase 2B catalytic subunit A2

1

1

High-throughput

0.407

High

566679

VATA
V-type proton ATPase catalytic subunit A

1

2

High-throughput

0.407

High

614543

PP2B1
Serine/threonine-protein phosphatase 2B catalytic subunit A1

1

1

High-throughput

0.407

High

690989

IF2G
Eukaryotic translation initiation factor 2 subunit gamma

1

1

High-throughput

0.407

High

333942

ADH1
Alcohol dehydrogenase 1

2

0

Small-scale

0.298

High

588257

HSP60
Heat shock protein 60, mitochondrial

2

0

Small-scale

0.298

High

687506

EF2
Elongation factor 2

2

0

Small-scale

0.298

High

599875

DIT1
Spore wall maturation protein DIT1

1

0

High-throughput

0.279

Low

691600

EIF3C
Eukaryotic translation initiation factor 3 subunit C

1

0

High-throughput

0.279

Low

732802

RL14A
Large ribosomal subunit protein eL14A

1

0

High-throughput

0.279

Low

977179

CLU
Clustered mitochondria protein 1

1

0

High-throughput

0.279

Low

989229

MRL1
Mannose 6-phosphate receptor-like protein 1

1

0

High-throughput

0.279

Low

997079

SELO
Protein adenylyltransferase SelO, mitochondrial

1

0

High-throughput

0.269

Low

141569

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.249

Low

340309

KPYK1
Pyruvate kinase 1

1

0

Small-scale

0.249

Low

340761

PGK
Phosphoglycerate kinase

1

0

Small-scale

0.249

Low

342396

CISY1
Citrate synthase, mitochondrial

1

0

Small-scale

0.249

Low

343040

ENO2
Enolase 2

1

0

Small-scale

0.249

Low

358303

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

368491

EF1A
Elongation factor 1-alpha

1

0

Small-scale

0.249

Low

405877

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.249

Low

408175

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.249

Low

413759

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.249

Low

471308

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

472441

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

480939

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

481439

RL2A
Large ribosomal subunit protein uL2A

1

0

High-throughput

0.249

Low

645704

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

660942

IDH1
Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial

1

0

Small-scale

0.249

Low

700673

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.249

Low

706546

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

730165

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.249

Low

752720

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.249

Low

755601

UBA4
Adenylyltransferase and sulfurtransferase UBA4

1

0

Small-scale

0.249

Low

770179

RGI2
Respiratory growth induced protein 2

1

0

High-throughput

0.249

Low

778775

FET4
Low-affinity Fe(2+) transport protein

1

0

Small-scale

0.249

Low

967816

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.249

Low

994432

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

0

Small-scale

0.249

Low

996343

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

361073

TBB
Tubulin beta chain

1

0

High-throughput

0.232

Low

390001

VDAC1
Mitochondrial outer membrane protein porin 1

1

0

High-throughput

0.232

Low

399666

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.232

Low

399799

RLA1
Large ribosomal subunit protein P1A

1

0

High-throughput

0.232

Low

410838

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.232

Low

420352

CALM
Calmodulin

1

0

High-throughput

0.232

Low

470771

RS21A
Small ribosomal subunit protein eS21A

1

0

High-throughput

0.232

Low

478600

HSP77
Import motor subunit, mitochondrial

1

0

High-throughput

0.232

Low

485857

IF4A
ATP-dependent RNA helicase eIF4A

1

0

High-throughput

0.232

Low

534858

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.232

Low

537499

ALF
Fructose-bisphosphate aldolase

1

0

High-throughput

0.232

Low

544565

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.232

Low

561088

EF3A
Elongation factor 3A

1

0

High-throughput

0.232

Low

562451

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

0

High-throughput

0.232

Low

572067

CLC1
Clathrin light chain

1

0

High-throughput

0.232

Low

593883

IF2A
Eukaryotic translation initiation factor 2 subunit alpha

1

0

High-throughput

0.232

Low

629671

RV161
Reduced viability upon starvation protein 161

1

0

High-throughput

0.232

Low

648258

KCC1
Calcium/calmodulin-dependent protein kinase I

1

0

High-throughput

0.232

Low

655810

GAC1
Serine/threonine-protein phosphatase 1 regulatory subunit GAC1

1

0

High-throughput

0.232

Low

713272

TSA1
Peroxiredoxin TSA1

1

0

High-throughput

0.232

Low

760980

TCPD
T-complex protein 1 subunit delta

1

0

High-throughput

0.232

Low

770033

YNU8
Uncharacterized protein YNL208W

1

0

High-throughput

0.232

Low

861128

YG3A
Uncharacterized protein YGR130C

1

0

High-throughput

0.232

Low

865729

RM22
Large ribosomal subunit protein uL22m

1

0

High-throughput

0.232

Low

865940

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.232

Low

967655

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

1

0

High-throughput

0.232

Low

973482

NOG1
Nucleolar GTP-binding protein 1

1

0

High-throughput

0.232

Low

991275

YD073
UPF0592 protein YDL073W

1

0

High-throughput

0.232

Low

994467

BRX1
Ribosome biogenesis protein BRX1

1

0

High-throughput

0.232

Low

1014953

NOP58
Nucleolar protein 58

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024