Protein: RQC2
Ribosome quality control complex subunit 2 (Translation-associated element 2)

Gene: RQC2
Organism: Saccharomyces cerevisiae S288C
Interactions: 123
UniProt ID: Q12532

Gene Ontology (top 5):
GO:0000049 - tRNA binding
GO:0003729 - mRNA binding
GO:0005737 - cytoplasm
GO:0010494 - cytoplasmic stress granule
GO:0022626 - cytosolic ribosome

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

544657

HSC82
ATP-dependent molecular chaperone HSC82

2

1

High-throughput

0.754

High

981172

LTN1
E3 ubiquitin-protein ligase listerin

3

0

Small-scale

0.628

High

983737

RQC1
Ribosome quality control complex subunit 1

3

0

Small-scale

0.628

High

399680

RLA0
Large ribosomal subunit protein uL10

3

0

Small-scale

0.622

High

367143

HSP82
ATP-dependent molecular chaperone HSP82

1

1

High-throughput

0.618

High

141597

RS9A
Small ribosomal subunit protein uS4A

1

0

High-throughput

0.586

High

636789

CDC48
Cell division control protein 48

2

0

Small-scale

0.585

High

704462

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

2

0

High-throughput

0.576

High

645167

RL16A
Large ribosomal subunit protein uL13A

2

0

High-throughput

0.559

High

492953

HSP71
Heat shock protein SSA1

2

1

High-throughput

0.552

High

513338

SSB1
Ribosome-associated molecular chaperone SSB1

2

1

High-throughput

0.552

High

769892

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.536

High

965083

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

1

High-throughput

0.536

High

405901

RL26A
Large ribosomal subunit protein uL24A

2

1

High-throughput

0.533

High

482013

RL12B
Large ribosomal subunit protein uL11B

1

0

High-throughput

0.517

High

676503

XPO1
Exportin-1

1

0

High-throughput

0.513

High

707256

NPL4
Nuclear protein localization protein 4

1

0

Small-scale

0.513

High

743076

GBLP
Small ribosomal subunit protein RACK1

1

0

Small-scale

0.513

High

858718

UFD1
Ubiquitin fusion degradation protein 1

1

0

Small-scale

0.513

High

764179

RV167
Reduced viability upon starvation protein 167

1

1

High-throughput

0.501

High

382822

RL24A
Large ribosomal subunit protein eL24A

1

1

High-throughput

0.479

High

405303

RL17A
Large ribosomal subunit protein uL22A

1

1

High-throughput

0.479

High

621531

RL24B
Large ribosomal subunit protein eL24B

1

1

High-throughput

0.479

High

641113

RL5
Large ribosomal subunit protein uL18

1

1

High-throughput

0.479

High

784254

RL10
Large ribosomal subunit protein uL16

1

1

High-throughput

0.479

High

859652

LSG1
Large subunit GTPase 1

1

1

High-throughput

0.479

High

976898

HAS1
ATP-dependent RNA helicase HAS1

1

1

High-throughput

0.470

High

698990

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

Small-scale

0.460

High

987951

NDE1
Nuclear distribution protein nudE homolog 1

1

0

High-throughput

0.460

High

404747

RL7A
Large ribosomal subunit protein uL30A

1

0

High-throughput

0.458

High

407415

RS3
Small ribosomal subunit protein uS3

1

0

High-throughput

0.458

High

408200

RS13
Small ribosomal subunit protein uS15

1

0

High-throughput

0.458

High

413786

RS14A
Small ribosomal subunit protein uS11A

1

0

High-throughput

0.458

High

482529

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

482960

RL35A
Large ribosomal subunit protein uL29A

1

0

High-throughput

0.458

High

534866

RL30
Large ribosomal subunit protein eL30

1

0

High-throughput

0.458

High

535169

RL3
Large ribosomal subunit protein uL3

1

0

High-throughput

0.458

High

632166

RS2
Small ribosomal subunit protein uS5

1

0

High-throughput

0.458

High

700704

RSSA1
Small ribosomal subunit protein uS2A

1

0

High-throughput

0.458

High

730190

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

741278

GLYM
Serine hydroxymethyltransferase, mitochondrial

1

0

High-throughput

0.458

High

752745

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

763927

IF2P
Eukaryotic translation initiation factor 5B

1

0

High-throughput

0.458

High

820252

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

865519

JJJ1
J protein JJJ1

1

0

High-throughput

0.458

High

967842

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

975881

TOM1
E3 ubiquitin-protein ligase TOM1

1

0

High-throughput

0.458

High

978147

HMO1
High mobility group protein 1

1

0

High-throughput

0.458

High

979282

VMS1
tRNA endonuclease VMS1

1

0

Small-scale

0.458

High

995853

SGO1
Shugoshin

1

0

High-throughput

0.458

High

1015291

RIO1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

495399

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

710844

CASP
Protein CASP

1

1

High-throughput

0.439

High

357581

RLA4
Large ribosomal subunit protein P2B

1

1

High-throughput

0.437

High

392230

H2A1
Histone H2A.1

1

1

High-throughput

0.437

High

392618

H2A2
Histone H2A.2

1

1

High-throughput

0.437

High

399804

RLA1
Large ribosomal subunit protein P1A

1

1

High-throughput

0.437

High

399941

RLA2
Large ribosomal subunit protein P2A

1

1

High-throughput

0.437

High

404930

RL9A
Large ribosomal subunit protein uL6A

1

1

High-throughput

0.437

High

405080

RL6B
Large ribosomal subunit protein eL6B

1

1

High-throughput

0.437

High

471849

RL27A
Large ribosomal subunit protein eL27A

1

1

High-throughput

0.437

High

471942

RL27B
Large ribosomal subunit protein eL27B

1

1

High-throughput

0.437

High

477506

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

1

Small-scale

0.437

High

482808

RL19B
Large ribosomal subunit protein eL19

1

1

High-throughput

0.437

High

496108

RLA3
Large ribosomal subunit protein P1B

1

1

High-throughput

0.437

High

564400

RL8A
Large ribosomal subunit protein eL8A

1

1

High-throughput

0.437

High

638909

SPB4
ATP-dependent rRNA helicase SPB4

1

1

High-throughput

0.437

High

667311

RL8B
Large ribosomal subunit protein eL8B

1

1

High-throughput

0.437

High

775106

RL34B
Large ribosomal subunit protein eL34B

1

1

High-throughput

0.437

High

810310

RL17B
Large ribosomal subunit protein uL22B

1

1

High-throughput

0.437

High

846322

RL9B
Large ribosomal subunit protein uL6B

1

1

High-throughput

0.437

High

860275

RL26B
Large ribosomal subunit protein uL24B

1

1

High-throughput

0.437

High

953530

RL34A
Large ribosomal subunit protein eL34A

1

1

High-throughput

0.437

High

970375

RL6A
Large ribosomal subunit protein eL6A

1

1

High-throughput

0.437

High

1015720

RL11B
Large ribosomal subunit protein uL5B

1

1

High-throughput

0.437

High

705848

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.426

High

810217

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

960035

SEN1
Helicase SEN1

1

0

Small-scale

0.426

High

1015476

HSP42
Heat shock protein 42

1

0

High-throughput

0.426

High

731163

LHS1
Heat shock protein 70 homolog LHS1

1

2

High-throughput

0.407

High

383426

RL25
Large ribosomal subunit protein uL23

2

0

High-throughput

0.305

High

481449

RL2A
Large ribosomal subunit protein uL2A

2

0

High-throughput

0.305

High

778900

NOP2
25S rRNA

1

0

High-throughput

0.279

Low

858594

TAF6
Transcription initiation factor TFIID subunit 6

1

0

High-throughput

0.279

Low

976008

GCN5
Histone acetyltransferase GCN5

1

0

High-throughput

0.279

Low

678197

ZIP1
Synaptonemal complex protein ZIP1

1

0

High-throughput

0.251

Low

959909

NUM1
Nuclear migration protein NUM1

1

0

High-throughput

0.251

Low

145803

RL36B
Large ribosomal subunit protein eL36B

1

0

High-throughput

0.249

Low

356808

H4
Histone H4

1

0

High-throughput

0.249

Low

358330

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.249

Low

406080

RL33A
Large ribosomal subunit protein eL33A

1

0

High-throughput

0.249

Low

406431

RL15A
Large ribosomal subunit protein eL15A

1

0

High-throughput

0.249

Low

406628

RL22A
Large ribosomal subunit protein eL22A

1

0

High-throughput

0.249

Low

426223

RS19A
Small ribosomal subunit protein eS19A

1

0

High-throughput

0.249

Low

471330

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

472468

RL31A
Large ribosomal subunit protein eL31A

1

0

High-throughput

0.249

Low

479015

RL20B
Large ribosomal subunit protein eL20B

1

0

High-throughput

0.249

Low

479197

RL43B
Large ribosomal subunit protein eL43B

1

0

High-throughput

0.249

Low

480394

RS6A
Small ribosomal subunit protein eS6A

1

0

High-throughput

0.249

Low

480961

RS8A
Small ribosomal subunit protein eS8A

1

0

High-throughput

0.249

Low

499129

RL4A
Large ribosomal subunit protein uL4A

1

0

High-throughput

0.249

Low

558343

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.249

Low

634841

KRR1
KRR1 small subunit processome component

1

0

High-throughput

0.249

Low

645728

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.249

Low

663766

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

701633

SC61A
Protein transport protein SEC61

1

0

High-throughput

0.249

Low

706571

RS3A1
Small ribosomal subunit protein eS1A

1

0

High-throughput

0.249

Low

732810

RL14A
Large ribosomal subunit protein eL14A

1

0

High-throughput

0.249

Low

758040

SSN2
Mediator of RNA polymerase II transcription subunit 13

1

0

Small-scale

0.249

Low

762698

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

770479

RL13B
Large ribosomal subunit protein eL13B

1

0

High-throughput

0.249

Low

792644

UTP10
U3 small nucleolar RNA-associated protein 10

1

0

High-throughput

0.249

Low

824775

RL37A
Large ribosomal subunit protein eL37A

1

0

High-throughput

0.249

Low

972310

RL21A
Large ribosomal subunit protein eL21A

1

0

High-throughput

0.249

Low

978401

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.249

Low

979094

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.249

Low

986300

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

996366

RS10A
Small ribosomal subunit protein eS10A

1

0

High-throughput

0.249

Low

743751

HMT1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.238

Low

761356

CAJ1
Protein CAJ1

1

0

High-throughput

0.232

Low

772599

JEM1
DnaJ-like chaperone JEM1

1

0

High-throughput

0.232

Low

837484

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

0

High-throughput

0.232

Low

982963

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024