Protein: H2AZ
Histone H2A.Z

Gene: H2AZ, HTZ1
Organism: Saccharomyces cerevisiae S288C
Interactions: 222
UniProt ID: Q12692

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000786 - nucleosome
GO:0000791 - euchromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0003682 - chromatin binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

627716

NAP1
Nucleosome assembly protein

15

19

Small-scale

0.981

High

983753

SWR1
Helicase SWR1

11

20

Small-scale

0.975

High

355708

H2B1
Histone H2B.1

11

20

Small-scale

0.975

High

976146

VPS72
Vacuolar protein sorting-associated protein 72

9

7

Small-scale

0.972

High

902164

H3
Histone H3

10

20

Small-scale

0.970

High

356810

H4
Histone H4

10

15

Small-scale

0.969

High

356059

H2B2
Histone H2B.2

10

20

Small-scale

0.967

High

392232

H2A1
Histone H2A.1

6

15

Small-scale

0.950

High

392620

H2A2
Histone H2A.2

7

14

Small-scale

0.946

High

858862

IMB5
Importin subunit beta-5

6

10

Small-scale

0.938

High

766996

CHZ1
Histone H2A.Z-specific chaperone CHZ1

9

0

Small-scale

0.910

High

1015724

H2AZ
Histone H2A.Z

3

17

Small-scale

0.871

High

692987

SPT16
FACT complex subunit SPT16

3

8

Small-scale

0.853

High

744936

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

3

20

High-throughput

0.817

High

946169

ARP4
Actin-related protein 4

8

17

Small-scale

0.746

High

978066

RUVB1
RuvB-like protein 1

8

13

Small-scale

0.746

High

679813

SWC3
SWR1-complex protein 3

7

1

Small-scale

0.742

High

860116

SWC4
SWR1-complex protein 4

7

3

Small-scale

0.742

High

1015643

RUVB2
RuvB-like protein 2

7

13

Small-scale

0.742

High

689995

ASF1
Histone chaperone ASF1

2

1

Small-scale

0.737

High

696275

STH1
Nuclear protein STH1/NPS1

2

20

High-throughput

0.737

High

697461

CHD1
Chromo domain-containing protein 1

2

20

High-throughput

0.737

High

767773

IMB4
Importin subunit beta-4

2

9

Small-scale

0.737

High

979872

POB3
FACT complex subunit POB3

2

11

High-throughput

0.737

High

728789

BDF1
Bromodomain-containing factor 1

6

20

Small-scale

0.727

High

866334

AF9
Protein AF-9 homolog

5

7

Small-scale

0.714

High

887728

ACT
Actin

5

8

Small-scale

0.712

High

1015688

ARP6
Actin-like protein ARP6

5

11

Small-scale

0.706

High

976394

VPS71
Vacuolar protein sorting-associated protein 71

6

0

Small-scale

0.699

High

678759

RAD16
DNA repair protein RAD16

1

18

High-throughput

0.691

High

748526

SWC5
SWR1-complex protein 5

4

7

Small-scale

0.691

High

862754

H1
Histone H1

4

1

Small-scale

0.685

High

988743

SWC7
SWR1-complex protein 7

3

1

Small-scale

0.656

High

976011

GCN5
Histone acetyltransferase GCN5

3

20

Small-scale

0.641

High

866882

HDA1
Histone deacetylase HDA1

2

14

Small-scale

0.633

High

772365

ATAD2
ATPase histone chaperone YTA7

3

6

High-throughput

0.633

High

861553

RT102
Regulator of Ty1 transposition protein 102

3

2

Small-scale

0.633

High

1014971

IOC2
ISWI one complex protein 2

3

1

High-throughput

0.633

High

768365

NCB1
Negative cofactor 2 complex subunit alpha

1

1

Small-scale

0.618

High

872840

ORC1
Origin recognition complex subunit 1

1

10

High-throughput

0.618

High

986319

SFH1
Chromatin structure-remodeling complex subunit SFH1

1

5

High-throughput

0.618

High

987860

IRC20
Uncharacterized ATP-dependent helicase IRC20

1

20

High-throughput

0.618

High

755479

TRA1
Transcription-associated protein 1

2

8

Small-scale

0.601

High

797199

EPL1
Enhancer of polycomb-like protein 1

2

4

Small-scale

0.601

High

996191

ESA1
Histone acetyltransferase ESA1

2

20

Small-scale

0.585

High

420197

TOP2
DNA topoisomerase 2

2

8

High-throughput

0.584

High

710460

SAS3
Histone acetyltransferase SAS3

2

18

Small-scale

0.584

High

743077

GBLP
Small ribosomal subunit protein RACK1

2

7

High-throughput

0.584

High

544659

HSC82
ATP-dependent molecular chaperone HSC82

3

3

High-throughput

0.578

High

667659

MCM2
DNA replication licensing factor MCM2

1

20

High-throughput

0.575

High

687777

BTAF1
TATA-binding protein-associated factor MOT1

1

20

High-throughput

0.575

High

733328

SET3
SET domain-containing protein 3

1

11

High-throughput

0.575

High

770123

RT106
Histone chaperone RTT106

1

1

High-throughput

0.575

High

810384

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

13

High-throughput

0.575

High

858595

TAF6
Transcription initiation factor TFIID subunit 6

1

2

High-throughput

0.575

High

979005

IOC4
ISWI one complex protein 4

1

1

High-throughput

0.575

High

987582

RSC2
Chromatin structure-remodeling complex subunit RSC2

1

20

High-throughput

0.575

High

996427

ISW2
ISWI chromatin-remodeling complex ATPase ISW2

1

20

High-throughput

0.575

High

527084

TBP
TATA-box-binding protein

2

2

Small-scale

0.571

High

635545

RSC6
Chromatin structure-remodeling complex protein RSC6

2

3

High-throughput

0.571

High

698706

RSC7
Chromatin structure-remodeling complex subunit RSC7

2

1

High-throughput

0.571

High

716398

SPT10
Protein SPT10

2

1

High-throughput

0.571

High

757382

FKBP3
Peptidyl-prolyl cis-trans isomerase

2

7

High-throughput

0.571

High

797979

RSC8
Chromatin structure-remodeling complex protein RSC8

2

11

High-throughput

0.571

High

969450

RSC4
Chromatin structure-remodeling complex subunit RSC4

2

20

High-throughput

0.571

High

973839

HOS3
Histone deacetylase HOS3

2

17

High-throughput

0.571

High

974772

RSC9
Chromatin structure-remodeling complex subunit RSC9

2

2

High-throughput

0.571

High

986497

FKBP4
FK506-binding protein 4

2

7

High-throughput

0.571

High

991246

BDF2
Bromodomain-containing factor 2

2

20

High-throughput

0.571

High

1015573

ARP7
Actin-related protein 7

2

15

High-throughput

0.571

High

1014896

TAF10
Transcription initiation factor TFIID subunit 10

2

0

Small-scale

0.547

High

514225

NHP6A
Non-histone chromosomal protein 6A

1

20

High-throughput

0.541

High

513344

SSB1
Ribosome-associated molecular chaperone SSB1

1

8

High-throughput

0.536

High

705851

HSP78
Heat shock protein 78, mitochondrial

2

4

High-throughput

0.521

High

810754

NET1
Nucleolar protein NET1

2

1

High-throughput

0.521

High

412495

KIN28
Serine/threonine-protein kinase KIN28

1

6

High-throughput

0.501

High

605608

DBF2
Cell cycle protein kinase DBF2

1

12

Small-scale

0.501

High

693079

RPD3
Histone deacetylase RPD3

1

15

Small-scale

0.501

High

978111

CTK1
CTD kinase subunit alpha

1

10

High-throughput

0.501

High

732602

T2EA
Transcription initiation factor IIE subunit alpha

1

0

High-throughput

0.493

High

733995

RPF2
Ribosome biogenesis protein RPF2

1

2

High-throughput

0.489

High

859470

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

4

High-throughput

0.489

High

973526

ELP3
Elongator complex protein 3

1

0

Small-scale

0.480

High

981033

NAA40
N-alpha-acetyltransferase 40

1

0

High-throughput

0.480

High

367147

HSP82
ATP-dependent molecular chaperone HSP82

1

3

High-throughput

0.479

High

375547

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

6

High-throughput

0.479

High

407417

RS3
Small ribosomal subunit protein uS3

1

4

High-throughput

0.479

High

419510

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

2

High-throughput

0.479

High

589324

FKBP
FK506-binding protein 1

1

7

Small-scale

0.479

High

601779

RCC1
Guanine nucleotide exchange factor SRM1

1

5

Small-scale

0.479

High

607372

RFA1
Replication factor A protein 1

1

5

Small-scale

0.479

High

612187

APN1
Apurinic-apyrimidinic endonuclease 1

1

1

High-throughput

0.479

High

663773

TF2B
Transcription initiation factor IIB

1

2

High-throughput

0.479

High

668176

RIF1
Telomere length regulator protein RIF1

1

2

Small-scale

0.479

High

681116

HS104
Heat shock protein 104

1

4

High-throughput

0.479

High

698194

AFG2
ATPase family gene 2 protein

1

3

Small-scale

0.479

High

716532

SPT21
Protein SPT21

1

1

High-throughput

0.479

High

728351

DEF1
RNA polymerase II degradation factor 1

1

3

Small-scale

0.479

High

732819

BYE1
Transcription factor BYE1

1

2

High-throughput

0.479

High

744986

CHK1
Serine/threonine-protein kinase CHK1

1

2

High-throughput

0.479

High

746465

LDB7
Chromatin structure-remodeling complex protein RSC14

1

1

High-throughput

0.479

High

766376

SNU13
13 kDa ribonucleoprotein-associated protein

1

3

High-throughput

0.479

High

774027

MLP2
Protein MLP2

1

18

High-throughput

0.479

High

774975

MAM33
Mitochondrial acidic protein MAM33

1

1

High-throughput

0.479

High

775302

ULP2
Ubiquitin-like-specific protease 2

1

3

High-throughput

0.479

High

866590

APJ1
J domain-containing protein APJ1

1

6

High-throughput

0.479

High

971004

ABF2
ARS-binding factor 2, mitochondrial

1

20

High-throughput

0.479

High

978149

HMO1
High mobility group protein 1

1

20

High-throughput

0.479

High

980186

ERB1
Ribosome biogenesis protein ERB1

1

6

High-throughput

0.479

High

982964

TAF9
Transcription initiation factor TFIID subunit 9

1

1

Small-scale

0.479

High

987083

TFC6
Transcription factor tau 91 kDa subunit

1

1

High-throughput

0.479

High

995854

SGO1
Shugoshin

1

1

High-throughput

0.479

High

1015220

PSH1
RING finger protein PSH1

1

6

Small-scale

0.479

High

1015693

CMR1
DNA damage-binding protein CMR1

1

13

High-throughput

0.479

High

1015725

HTL1
High temperature lethal protein 1

1

1

Small-scale

0.479

High

693898

SRP40
Suppressor protein SRP40

1

4

High-throughput

0.470

High

804934

SYEC
Glutamate--tRNA ligase, cytoplasmic

1

3

High-throughput

0.470

High

987369

CORO
Coronin-like protein

1

5

High-throughput

0.470

High

1015435

SMT3
Ubiquitin-like protein SMT3

1

0

High-throughput

0.460

High

698992

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

0

High-throughput

0.458

High

759482

STM1
Suppressor protein STM1

1

0

Small-scale

0.458

High

979500

YD514
Uncharacterized protein YDR514C

1

0

Small-scale

0.458

High

979821

DPB4
DNA polymerase epsilon subunit D

1

0

Small-scale

0.458

High

987124

VPS74
Vacuolar protein sorting-associated protein 74

1

0

High-throughput

0.458

High

996031

IES4
Ino eighty subunit 4

1

0

Small-scale

0.458

High

1015000

MLH3
DNA mismatch repair protein MLH3

1

0

High-throughput

0.458

High

419416

HAP2
Transcriptional activator HAP2

1

1

High-throughput

0.445

High

457092

SWI6
Regulatory protein SWI6

1

7

High-throughput

0.445

High

492960

HSP71
Heat shock protein SSA1

1

8

High-throughput

0.445

High

495405

HSP72
Heat shock protein SSA2

1

8

High-throughput

0.445

High

515096

MCM1
Pheromone receptor transcription factor

1

2

High-throughput

0.445

High

605274

AFT1
Iron-regulated transcriptional activator AFT1

1

1

High-throughput

0.445

High

622207

MCM3
DNA replication licensing factor MCM3

1

20

High-throughput

0.445

High

628915

SWI4
Regulatory protein SWI4

1

7

High-throughput

0.445

High

633728

MAS5
Mitochondrial protein import protein MAS5

1

6

High-throughput

0.445

High

667906

MCM5
Minichromosome maintenance protein 5

1

20

High-throughput

0.445

High

690648

FKBP2
Peptidyl-prolyl cis-trans isomerase FPR2

1

5

High-throughput

0.445

High

695892

HSP7F
Heat shock protein homolog SSE1

1

13

High-throughput

0.445

High

710255

YOX1
Homeobox protein YOX1

1

3

High-throughput

0.445

High

715767

TAF14
Transcription initiation factor TFIID subunit 14

1

7

High-throughput

0.445

High

744722

TAF5
Transcription initiation factor TFIID subunit 5

1

7

High-throughput

0.445

High

754270

RSC30
Chromatin structure-remodeling complex protein RSC30

1

4

High-throughput

0.445

High

761357

CAJ1
Protein CAJ1

1

7

High-throughput

0.445

High

766434

EAF5
Chromatin modification-related protein EAF5

1

2

Small-scale

0.445

High

769898

SSB2
Ribosome-associated molecular chaperone SSB2

1

8

High-throughput

0.445

High

797767

IOC3
ISWI one complex protein 3

1

2

High-throughput

0.445

High

805259

TAF1
Transcription initiation factor TFIID subunit 1

1

1

High-throughput

0.445

High

810792

SMC3
Structural maintenance of chromosomes protein 3

1

4

High-throughput

0.445

High

837509

TAF4
Transcription initiation factor TFIID subunit 4

1

3

High-throughput

0.445

High

859037

MCM6
DNA replication licensing factor MCM6

1

20

High-throughput

0.445

High

859364

ITC1
Imitation switch two complex protein 1

1

5

High-throughput

0.445

High

872895

ORC3
Origin recognition complex subunit 3

1

1

High-throughput

0.445

High

961535

CDC14
Tyrosine-protein phosphatase CDC14

1

2

High-throughput

0.445

High

970988

TBF1
Protein TBF1

1

1

High-throughput

0.445

High

977028

YE11B
Transposon Ty1-ER1 Gag-Pol polyprotein

1

1

High-throughput

0.445

High

977549

TAF12
Transcription initiation factor TFIID subunit 12

1

1

High-throughput

0.445

High

977725

GIS1
Transcriptional activator/repressor GIS1

1

3

High-throughput

0.445

High

981166

RCO1
Transcriptional regulatory protein RCO1

1

20

High-throughput

0.445

High

983306

ARP9
Actin-like protein ARP9

1

12

High-throughput

0.445

High

988521

RSC3
Chromatin structure-remodeling complex protein RSC3

1

4

High-throughput

0.445

High

993159

RSC58
Chromatin structure-remodeling complex protein RSC58

1

1

High-throughput

0.445

High

1015553

ARP8
Actin-like protein ARP8

1

12

High-throughput

0.445

High

1015592

EAF3
Chromatin modification-related protein EAF3

1

7

High-throughput

0.445

High

1015675

RLF2
Chromatin assembly factor 1 subunit p90

1

3

High-throughput

0.445

High

141598

RS9A
Small ribosomal subunit protein uS4A

1

1

High-throughput

0.437

High

342267

ATP6
ATP synthase subunit a

1

1

Small-scale

0.437

High

358331

RS17A
Small ribosomal subunit protein eS17A

1

3

High-throughput

0.437

High

383429

RL25
Large ribosomal subunit protein uL23

1

2

High-throughput

0.437

High

405902

RL26A
Large ribosomal subunit protein uL24A

1

5

High-throughput

0.437

High

408201

RS13
Small ribosomal subunit protein uS15

1

2

High-throughput

0.437

High

413788

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.437

High

426224

RS19A
Small ribosomal subunit protein eS19A

1

4

High-throughput

0.437

High

471331

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.437

High

472469

RL31A
Large ribosomal subunit protein eL31A

1

3

High-throughput

0.437

High

480395

RS6A
Small ribosomal subunit protein eS6A

1

3

High-throughput

0.437

High

480962

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.437

High

632168

RS2
Small ribosomal subunit protein uS5

1

3

High-throughput

0.437

High

634844

KRR1
KRR1 small subunit processome component

1

5

High-throughput

0.437

High

638911

SPB4
ATP-dependent rRNA helicase SPB4

1

8

High-throughput

0.437

High

645729

RS7A
Small ribosomal subunit protein eS7A

1

2

High-throughput

0.437

High

700706

RSSA1
Small ribosomal subunit protein uS2A

1

1

High-throughput

0.437

High

706572

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.437

High

730192

RS27A
Small ribosomal subunit protein eS27A

1

1

High-throughput

0.437

High

737246

LONM
Lon protease homolog, mitochondrial

1

3

High-throughput

0.437

High

752746

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.437

High

754231

CIC1
Proteasome-interacting protein CIC1

1

2

High-throughput

0.437

High

762702

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

765117

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

1

High-throughput

0.437

High

776558

RLP7
Ribosome biogenesis protein RLP7

1

2

High-throughput

0.437

High

865337

GIS2
Zinc finger protein GIS2

1

2

High-throughput

0.437

High

866824

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.437

High

967844

RS15
Small ribosomal subunit protein uS19

1

4

High-throughput

0.437

High

982720

COX20
Cytochrome c oxidase assembly protein COX20, mitochondrial

1

2

High-throughput

0.437

High

994478

BRX1
Ribosome biogenesis protein BRX1

1

7

High-throughput

0.437

High

996367

RS10A
Small ribosomal subunit protein eS10A

1

3

High-throughput

0.437

High

540663

CYPH
Peptidyl-prolyl cis-trans isomerase

1

0

High-throughput

0.426

High

809645

YPP1
Cargo-transport protein YPP1

1

0

High-throughput

0.426

High

872861

MOT3
Transcriptional activator/repressor MOT3

1

0

High-throughput

0.426

High

989518

RAF
Trans-acting factor D

1

0

High-throughput

0.426

High

993245

CDC45
Cell division control protein 45

1

0

High-throughput

0.426

High

619651

MPCP
Mitochondrial phosphate carrier protein

1

4

High-throughput

0.407

High

707961

GCN1
eIF-2-alpha kinase activator GCN1

1

8

High-throughput

0.407

High

767448

UTP7
U3 small nucleolar RNA-associated protein 7

1

6

High-throughput

0.407

High

775693

DJP1
DnaJ-like protein 1

1

7

High-throughput

0.407

High

798402

CSK2B
Casein kinase II subunit beta

1

2

High-throughput

0.407

High

805177

STU2
Protein STU2

1

3

High-throughput

0.407

High

817303

HLJ1
Protein HLJ1

1

3

High-throughput

0.407

High

988627

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

1

High-throughput

0.407

High

811267

MPS3
Spindle pole body assembly component MPS3

6

0

Small-scale

0.382

High

873202

TMEDA
Endoplasmic reticulum vesicle protein 25

1

0

High-throughput

0.269

Low

482531

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.249

Low

660395

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.249

Low

860426

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.249

Low

994456

YO075
Uncharacterized ABC transporter ATP-binding protein/permease YOL075C

1

0

Small-scale

0.249

Low

410843

ILV5
Ketol-acid reductoisomerase, mitochondrial

1

0

High-throughput

0.232

Low

423494

PUR2
Bifunctional purine biosynthetic protein ADE5,7 [Includes: Phosphoribosylamine--glycine ligase

1

0

High-throughput

0.232

Low

580599

FAS2
Fatty acid synthase subunit alpha

1

0

High-throughput

0.232

Low

604907

GAS1
1,3-beta-glucanosyltransferase GAS1

1

0

High-throughput

0.232

Low

741220

GLYC
Serine hydroxymethyltransferase, cytosolic

1

0

High-throughput

0.232

Low

810220

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low

814739

LCF4
Long-chain-fatty-acid--CoA ligase 4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024