Protein: RRP12
Ribosomal RNA-processing protein 12

Gene: RRP12
Organism: Saccharomyces cerevisiae S288C
Interactions: 201
UniProt ID: Q12754

Gene Ontology (top 5):
GO:0000462 - maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GO:0003723 - RNA binding
GO:0003729 - mRNA binding
GO:0005634 - nucleus
GO:0005730 - nucleolus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

748755

ENP1
Essential nuclear protein 1

12

1

Small-scale

0.757

High

742095

NOP4
Nucleolar protein 4

7

1

Small-scale

0.749

High

987708

NOC4
Nucleolar complex protein 4

7

2

Small-scale

0.743

High

991199

TSR1
Ribosome biogenesis protein TSR1

6

2

Small-scale

0.732

High

1015251

MAK21
Ribosome biogenesis protein MAK21

6

2

High-throughput

0.730

High

635675

PWP2
Periodic tryptophan protein 2

5

3

Small-scale

0.714

High

770078

RIO2
Serine/threonine-protein kinase RIO2

4

2

Small-scale

0.691

High

979097

DHR1
Probable ATP-dependent RNA helicase DHR1

4

2

Small-scale

0.676

High

784545

DIM1
Dimethyladenosine transferase

5

0

Small-scale

0.676

High

982929

RRP5
rRNA biogenesis protein RRP5

4

1

Small-scale

0.672

High

866296

NOP15
Ribosome biogenesis protein 15

3

1

High-throughput

0.662

High

634845

KRR1
KRR1 small subunit processome component

3

1

High-throughput

0.656

High

979269

UTP15
U3 small nucleolar RNA-associated protein 15

3

1

High-throughput

0.656

High

860542

SLX9
Ribosome biogenesis protein SLX9

4

0

Small-scale

0.653

High

866092

NAT10
RNA cytidine acetyltransferase

3

1

Small-scale

0.640

High

1015293

RIO1
Serine/threonine-protein kinase RIO1

3

2

Small-scale

0.640

High

756817

UTP9
U3 small nucleolar RNA-associated protein 9

3

0

High-throughput

0.638

High

995881

UTP16
U3 small nucleolar RNA-associated protein 16

3

0

High-throughput

0.638

High

1015745

NOP14
Nucleolar complex protein 14

3

0

High-throughput

0.638

High

688019

IMB3
Importin subunit beta-3

3

0

Small-scale

0.634

High

1015681

NOP58
Nucleolar protein 58

3

3

High-throughput

0.633

High

731899

EBP2
rRNA-processing protein EBP2

3

0

High-throughput

0.633

High

1014989

NOP53
Ribosome biogenesis protein NOP53

3

0

High-throughput

0.618

High

792646

UTP10
U3 small nucleolar RNA-associated protein 10

3

0

High-throughput

0.613

High

754232

CIC1
Proteasome-interacting protein CIC1

2

2

High-throughput

0.611

High

767449

UTP7
U3 small nucleolar RNA-associated protein 7

2

2

High-throughput

0.611

High

797425

LOC1
60S ribosomal subunit assembly/export protein LOC1

2

0

High-throughput

0.607

High

704464

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

2

0

High-throughput

0.602

High

495410

HSP72
Heat shock protein SSA2

2

2

High-throughput

0.601

High

776559

RLP7
Ribosome biogenesis protein RLP7

2

2

High-throughput

0.594

High

696113

HSP79
Heat shock protein homolog SSE2

2

4

High-throughput

0.588

High

480963

RS8A
Small ribosomal subunit protein eS8A

2

1

High-throughput

0.584

High

988662

UTP4
U3 small nucleolar RNA-associated protein 4

2

3

Small-scale

0.584

High

997070

BMS1
Ribosome biogenesis protein BMS1

2

2

High-throughput

0.584

High

768074

NSA2
Ribosome biogenesis protein NSA2

2

0

High-throughput

0.569

High

655919

GAR1
H/ACA ribonucleoprotein complex subunit GAR1

2

0

High-throughput

0.563

High

558347

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

0

High-throughput

0.559

High

709394

LTV1
Protein LTV1

2

0

Small-scale

0.559

High

716014

UTP20
U3 small nucleolar RNA-associated protein 20

2

0

Small-scale

0.559

High

979756

UTP14
U3 small nucleolar RNA-associated protein 14

2

0

High-throughput

0.559

High

1015746

PNO1
Pre-rRNA-processing protein PNO1

2

0

Small-scale

0.559

High

405306

RL17A
Large ribosomal subunit protein uL22A

1

1

High-throughput

0.536

High

485610

SSBP1
Single-stranded nucleic acid-binding protein

1

1

High-throughput

0.536

High

492969

HSP71
Heat shock protein SSA1

1

2

High-throughput

0.536

High

513352

SSB1
Ribosome-associated molecular chaperone SSB1

1

2

High-throughput

0.536

High

535173

RL3
Large ribosomal subunit protein uL3

1

1

High-throughput

0.536

High

597925

PWP1
Periodic tryptophan protein 1

1

1

High-throughput

0.536

High

613773

RS3A2
Small ribosomal subunit protein eS1B

1

2

High-throughput

0.536

High

859471

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

3

High-throughput

0.536

High

974203

FRK1
Fatty acyl-CoA synthetase and RNA processing-associated kinase 1

1

1

High-throughput

0.536

High

1015318

RL7B
Large ribosomal subunit protein uL30B

1

2

High-throughput

0.536

High

698033

SLA1
Actin cytoskeleton-regulatory complex protein SLA1

1

0

High-throughput

0.518

High

589468

PRP2
Pre-mRNA-splicing factor ATP-dependent RNA helicase-like protein PRP2

1

3

High-throughput

0.515

High

357745

RL28
Large ribosomal subunit protein uL15

1

0

High-throughput

0.513

High

566248

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.513

High

641117

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.513

High

688546

KNS1
Dual specificity protein kinase KNS1

1

0

High-throughput

0.513

High

791296

KRI1
Protein KRI1

1

0

High-throughput

0.513

High

811950

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

0

High-throughput

0.513

High

864648

BRE5
UBP3-associated protein BRE5

1

0

High-throughput

0.513

High

865474

ELOA1
Elongin-A

1

0

High-throughput

0.513

High

964753

BCK1
Serine/threonine-protein kinase BCK1/SLK1/SSP31

1

0

High-throughput

0.513

High

965087

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

0

High-throughput

0.513

High

979481

PUF6
Pumilio homology domain family member 6

1

0

High-throughput

0.513

High

987351

MAG2
E3 ubiquitin-protein ligase MAG2

1

0

High-throughput

0.513

High

991552

NOP6
Nucleolar protein 6

1

0

High-throughput

0.513

High

995914

DIA2
Protein DIA2

1

0

High-throughput

0.513

High

698994

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

2

Small-scale

0.501

High

971884

NU100
Nucleoporin NUP100/NSP100

1

2

Small-scale

0.501

High

971926

NU116
Nucleoporin NUP116/NSP116

1

2

Small-scale

0.501

High

622908

DPB2
DNA polymerase epsilon subunit B

1

0

High-throughput

0.493

High

777336

SA185
SIT4-associating protein SAP185

1

0

High-throughput

0.493

High

997054

YP216
Putative ISWI chromatin-remodeling complex subunit YPL216W

1

0

High-throughput

0.493

High

141599

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.479

High

383430

RL25
Large ribosomal subunit protein uL23

1

1

High-throughput

0.479

High

407420

RS3
Small ribosomal subunit protein uS3

1

1

High-throughput

0.479

High

408202

RS13
Small ribosomal subunit protein uS15

1

1

High-throughput

0.479

High

413789

RS14A
Small ribosomal subunit protein uS11A

1

1

High-throughput

0.479

High

426226

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.479

High

480396

RS6A
Small ribosomal subunit protein eS6A

1

1

High-throughput

0.479

High

481254

RL1A
Large ribosomal subunit protein uL1A

1

3

High-throughput

0.479

High

622356

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

1

3

Small-scale

0.479

High

628630

SIS1
Protein SIS1

1

1

High-throughput

0.479

High

632169

RS2
Small ribosomal subunit protein uS5

1

1

High-throughput

0.479

High

700117

IMP3
U3 small nucleolar ribonucleoprotein protein IMP3

1

2

High-throughput

0.479

High

700708

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.479

High

706573

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.479

High

707165

DCA13
Protein SOF1

1

1

High-throughput

0.479

High

733621

RL1D1
Ribosome biogenesis protein UTP30

1

2

High-throughput

0.479

High

743079

GBLP
Small ribosomal subunit protein RACK1

1

1

High-throughput

0.479

High

744264

MAK5
ATP-dependent RNA helicase MAK5

1

3

High-throughput

0.479

High

758493

RRP8
25S rRNA

1

1

High-throughput

0.479

High

775305

ULP2
Ubiquitin-like-specific protease 2

1

1

High-throughput

0.479

High

809609

RRP41
Exosome complex component SKI6

1

1

High-throughput

0.479

High

860920

PESC
Pescadillo homolog

1

1

High-throughput

0.479

High

864756

ESF2
Pre-rRNA-processing protein ESF2

1

1

High-throughput

0.479

High

866593

APJ1
J domain-containing protein APJ1

1

1

High-throughput

0.479

High

902165

H3
Histone H3

1

2

High-throughput

0.479

High

972040

ULP1
Ubiquitin-like-specific protease 1

1

1

High-throughput

0.479

High

973499

NOG1
Nucleolar GTP-binding protein 1

1

1

High-throughput

0.479

High

973702

UTP17
NET1-associated nuclear protein 1

1

3

High-throughput

0.479

High

976899

HAS1
ATP-dependent RNA helicase HAS1

1

2

High-throughput

0.479

High

978069

RUVB1
RuvB-like protein 1

1

1

High-throughput

0.479

High

978660

UTP5
U3 small nucleolar RNA-associated protein 5

1

3

High-throughput

0.479

High

984230

HRQ1
ATP-dependent helicase HRQ1

1

2

Small-scale

0.479

High

984331

RRP45
Exosome complex component RRP45

1

2

High-throughput

0.479

High

985447

UTP13
U3 small nucleolar RNA-associated protein 13

1

4

High-throughput

0.479

High

985840

UTP21
U3 small nucleolar RNA-associated protein 21

1

4

High-throughput

0.479

High

987625

RRP9
Ribosomal RNA-processing protein 9

1

3

High-throughput

0.479

High

988496

BFR2
Protein BFR2

1

1

High-throughput

0.479

High

996368

RS10A
Small ribosomal subunit protein eS10A

1

1

High-throughput

0.479

High

1015335

UTP12
U3 small nucleolar RNA-associated protein 12

1

4

High-throughput

0.479

High

1015411

RRP42
Exosome complex component RRP42

1

2

High-throughput

0.479

High

1015628

NOP56
Nucleolar protein 56

1

3

High-throughput

0.479

High

1015647

RUVB2
RuvB-like protein 2

1

1

High-throughput

0.479

High

1015694

CMR1
DNA damage-binding protein CMR1

1

2

High-throughput

0.479

High

376989

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

0

Small-scale

0.458

High

405903

RL26A
Large ribosomal subunit protein uL24A

1

0

High-throughput

0.458

High

408506

RS31
Ubiquitin-ribosomal protein eS31 fusion protein [Cleaved into: Ubiquitin; Small ribosomal subunit protein eS31

1

0

High-throughput

0.458

High

456728

RIR2
Ribonucleoside-diphosphate reductase small chain 1

1

0

Small-scale

0.458

High

479844

RS4A
Small ribosomal subunit protein eS4A

1

0

High-throughput

0.458

High

482534

RS18A
Small ribosomal subunit protein uS13A

1

0

High-throughput

0.458

High

524494

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.458

High

606793

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.458

High

608499

SAN1
Protein SAN1

1

0

Small-scale

0.458

High

619992

PSB6
Proteasome subunit beta type-6

1

0

High-throughput

0.458

High

630299

RRP43
Exosome complex component RRP43

1

0

High-throughput

0.458

High

630568

RRP7
Ribosomal RNA-processing protein 7

1

0

High-throughput

0.458

High

635180

YCQ6
Uncharacterized protein YCR016W

1

0

High-throughput

0.458

High

645730

RS7A
Small ribosomal subunit protein eS7A

1

0

High-throughput

0.458

High

663781

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.458

High

688507

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

0

High-throughput

0.458

High

711096

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.458

High

730193

RS27A
Small ribosomal subunit protein eS27A

1

0

High-throughput

0.458

High

733686

LAS1
Protein LAS1

1

0

Small-scale

0.458

High

733996

RPF2
Ribosome biogenesis protein RPF2

1

0

Small-scale

0.458

High

751011

KPR2
Ribose-phosphate pyrophosphokinase 2

1

0

High-throughput

0.458

High

752748

RS20
Small ribosomal subunit protein uS10

1

0

High-throughput

0.458

High

753201

DBP8
ATP-dependent RNA helicase DBP8

1

0

High-throughput

0.458

High

755018

RRP4
Exosome complex component RRP4

1

0

High-throughput

0.458

High

755222

LRP1
Exosome complex protein LRP1

1

0

High-throughput

0.458

High

764281

NOC2
Nucleolar complex protein 2

1

0

High-throughput

0.458

High

772706

UTP18
U3 small nucleolar RNA-associated protein 18

1

0

High-throughput

0.458

High

774301

RRT14
Regulator of rDNA transcription protein 14

1

0

High-throughput

0.458

High

774768

UTP25
U3 small nucleolar RNA-associated protein 25

1

0

High-throughput

0.458

High

775412

FAF1
Protein FAF1

1

0

High-throughput

0.458

High

799884

ROK1
ATP-dependent RNA helicase ROK1

1

0

High-throughput

0.458

High

810962

MTR4
ATP-dependent RNA helicase DOB1

1

0

High-throughput

0.458

High

811378

NOP9
Nucleolar protein 9

1

0

Small-scale

0.458

High

811585

MPP10
U3 small nucleolar RNA-associated protein MPP10

1

0

High-throughput

0.458

High

811817

URB2
Nucleolar pre-ribosomal-associated protein 2

1

0

High-throughput

0.458

High

812184

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

812637

YJ9I
Uncharacterized protein YJR141W

1

0

Small-scale

0.458

High

816931

NOL10
Ribosome biogenesis protein ENP2

1

0

High-throughput

0.458

High

820253

RS12
Small ribosomal subunit protein eS12

1

0

High-throughput

0.458

High

860427

EIF2A
Eukaryotic translation initiation factor 2A

1

0

High-throughput

0.458

High

860782

UTP22
U3 small nucleolar RNA-associated protein 22

1

0

High-throughput

0.458

High

861058

UTP8
U3 small nucleolar RNA-associated protein 8

1

0

High-throughput

0.458

High

864554

TR112
Multifunctional methyltransferase subunit TRM112

1

0

Small-scale

0.458

High

865442

CSL4
Exosome complex component CSL4

1

0

High-throughput

0.458

High

865574

SQS1
Protein SQS1

1

0

High-throughput

0.458

High

866642

IMP4
U3 small nucleolar ribonucleoprotein protein IMP4

1

0

High-throughput

0.458

High

967845

RS15
Small ribosomal subunit protein uS19

1

0

High-throughput

0.458

High

970494

UTP6
U3 small nucleolar RNA-associated protein 6

1

0

High-throughput

0.458

High

972659

XRN2
5'-3' exoribonuclease 2

1

0

High-throughput

0.458

High

977868

MTQ2
eRF1 methyltransferase catalytic subunit MTQ2

1

0

High-throughput

0.458

High

978454

RRP17
Ribosomal RNA-processing protein 17

1

0

High-throughput

0.458

High

983790

FCF1
rRNA-processing protein FCF1

1

0

High-throughput

0.458

High

986302

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

986775

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

0

High-throughput

0.458

High

991385

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.458

High

992565

CMS1
Protein CMS1

1

0

High-throughput

0.458

High

993381

RCL1
RNA 3'-terminal phosphate cyclase-like protein

1

0

High-throughput

0.458

High

994591

RRP40
Exosome complex component RRP40

1

0

High-throughput

0.458

High

995642

NOB1
20S-pre-rRNA D-site endonuclease NOB1

1

0

Small-scale

0.458

High

995856

SGO1
Shugoshin

1

0

High-throughput

0.458

High

1014910

FCF2
rRNA-processing protein FCF2

1

0

High-throughput

0.458

High

1015093

SAS10
Something about silencing protein 10

1

0

High-throughput

0.458

High

1015664

RRP36
rRNA biogenesis protein RRP36

1

0

High-throughput

0.458

High

541936

NSP1
Nucleoporin NSP1

1

2

Small-scale

0.457

High

499133

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.445

High

633731

MAS5
Mitochondrial protein import protein MAS5

1

1

High-throughput

0.445

High

695896

HSP7F
Heat shock protein homolog SSE1

1

4

High-throughput

0.445

High

754846

SSZ1
Ribosome-associated complex subunit SSZ1

1

1

High-throughput

0.445

High

769901

SSB2
Ribosome-associated molecular chaperone SSB2

1

2

High-throughput

0.445

High

472470

RL31A
Large ribosomal subunit protein eL31A

1

1

High-throughput

0.437

High

959910

NUM1
Nuclear migration protein NUM1

1

1

High-throughput

0.437

High

340770

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.426

High

556403

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.426

High

681119

HS104
Heat shock protein 104

1

0

High-throughput

0.426

High

766563

PFD2
Prefoldin subunit 2

1

0

High-throughput

0.426

High

960036

SEN1
Helicase SEN1

1

0

Small-scale

0.426

High

1015479

HSP42
Heat shock protein 42

1

0

High-throughput

0.426

High

358332

RS17A
Small ribosomal subunit protein eS17A

2

0

High-throughput

0.318

High

471332

RS22A
Small ribosomal subunit protein uS8A

1

0

High-throughput

0.249

Low

471852

RL27A
Large ribosomal subunit protein eL27A

1

0

High-throughput

0.249

Low

689456

YBT1
ATP-dependent bile acid permease

1

0

Small-scale

0.249

Low

762704

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.249

Low

997016

AP3D
AP-3 complex subunit delta

1

0

High-throughput

0.249

Low

343049

ENO2
Enolase 2

1

0

High-throughput

0.232

Low

751441

FKS1
1,3-beta-glucan synthase component FKS1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024