Protein: SUB2
ATP-dependent RNA helicase SUB2 (EC 3.6.4.13) (Suppressor of BRR1 protein 2)

Gene: SUB2
Organism: Saccharomyces cerevisiae S288C
Interactions: 139
UniProt ID: Q07478

Gene Ontology (top 5):
GO:0000346 - transcription export complex
GO:0000398 - mRNA splicing, via spliceosome
GO:0000781 - chromosome, telomeric region
GO:0003723 - RNA binding
GO:0003724 - RNA helicase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

862769

THO2
THO complex subunit 2

4

11

Small-scale

0.892

High

558281

RPB3
DNA-directed RNA polymerase II subunit RPB3

3

3

Small-scale

0.827

High

991404

SUB2
ATP-dependent RNA helicase SUB2

2

17

High-throughput

0.800

High

991412

YRA1
RNA annealing protein YRA1

9

20

Small-scale

0.758

High

710228

NCBP1
Nuclear cap-binding protein complex subunit 1

2

4

Small-scale

0.754

High

568912

HPR1
THO complex subunit HPR1

11

0

Small-scale

0.727

High

706170

MFT1
THO complex subunit MFT1

7

0

Small-scale

0.711

High

141758

THP2
THO complex subunit THP2

5

0

Small-scale

0.684

High

865345

TEX1
Protein TEX1

3

14

Small-scale

0.656

High

692088

NAB2
Nuclear polyadenylated RNA-binding protein NAB2

3

4

Small-scale

0.650

High

731490

YRA2
RNA annealing protein YRA2

3

0

Small-scale

0.641

High

366974

HSP82
ATP-dependent molecular chaperone HSP82

3

9

High-throughput

0.633

High

767224

THO1
Protein THO1

2

1

High-throughput

0.620

High

356754

H4
Histone H4

1

5

High-throughput

0.618

High

440109

RPB2
DNA-directed RNA polymerase II subunit RPB2

1

1

High-throughput

0.618

High

485841

IF4A
ATP-dependent RNA helicase eIF4A

1

19

High-throughput

0.618

High

593788

DBP5
ATP-dependent RNA helicase DBP5

1

18

High-throughput

0.618

High

622344

PRP22
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP22

1

10

High-throughput

0.618

High

762030

DHH1
ATP-dependent RNA helicase DHH1

1

18

High-throughput

0.618

High

978019

RUVB1
RuvB-like protein 1

1

3

High-throughput

0.618

High

991411

RRP6
Exosome complex exonuclease RRP6

1

3

High-throughput

0.618

High

633993

GBP2
Serine/arginine

2

14

Small-scale

0.611

High

805134

SAC3
Nuclear mRNA export protein SAC3

2

3

Small-scale

0.601

High

965498

NOP3
Serine/arginine

2

20

Small-scale

0.600

High

991414

SMT3
Ubiquitin-like protein SMT3

2

6

High-throughput

0.600

High

544496

HSC82
ATP-dependent molecular chaperone HSC82

2

9

High-throughput

0.584

High

797601

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

13

High-throughput

0.584

High

771355

PSA6
Proteasome subunit alpha type-6

1

4

Small-scale

0.541

High

985280

MDM30
Mitochondrial distribution and morphology protein 30

1

0

Small-scale

0.537

High

715402

SPT7
Transcriptional activator SPT7

1

10

High-throughput

0.536

High

752274

KIC1
Serine/threonine-protein kinase KIC1

1

4

High-throughput

0.536

High

837472

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

4

High-throughput

0.536

High

864618

BRE5
UBP3-associated protein BRE5

1

6

High-throughput

0.536

High

970407

ADA2
Transcriptional adapter 2

1

2

High-throughput

0.536

High

975978

GCN5
Histone acetyltransferase GCN5

1

15

High-throughput

0.536

High

858575

TAF6
Transcription initiation factor TFIID subunit 6

1

0

High-throughput

0.513

High

355668

H2B1
Histone H2B.1

1

11

High-throughput

0.479

High

356029

H2B2
Histone H2B.2

1

11

High-throughput

0.479

High

361047

TBB
Tubulin beta chain

1

8

High-throughput

0.479

High

375521

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

6

High-throughput

0.479

High

376944

PABP
Polyadenylate-binding protein, cytoplasmic and nuclear

1

13

Small-scale

0.479

High

378248

PUR3
Phosphoribosylglycinamide formyltransferase

1

1

High-throughput

0.479

High

392216

H2A1
Histone H2A.1

1

4

High-throughput

0.479

High

392586

H2A2
Histone H2A.2

1

4

High-throughput

0.479

High

407351

RS3
Small ribosomal subunit protein uS3

1

5

High-throughput

0.479

High

413731

RS14A
Small ribosomal subunit protein uS11A

1

3

High-throughput

0.479

High

426177

RS19A
Small ribosomal subunit protein eS19A

1

6

High-throughput

0.479

High

492589

HSP71
Heat shock protein SSA1

1

12

High-throughput

0.479

High

498601

METK1
S-adenosylmethionine synthase 1

1

3

High-throughput

0.479

High

515019

RNA1
Ran GTPase-activating protein 1

1

5

High-throughput

0.479

High

524458

CAF20
Cap-associated protein CAF20

1

2

High-throughput

0.479

High

549840

UBC4
Ubiquitin-conjugating enzyme E2 4

1

2

High-throughput

0.479

High

578570

SEC18
Vesicular-fusion protein SEC18

1

2

High-throughput

0.479

High

602771

MCK1
Protein kinase MCK1

1

8

High-throughput

0.479

High

608489

SAN1
Protein SAN1

1

1

Small-scale

0.479

High

628518

SIS1
Protein SIS1

1

6

High-throughput

0.479

High

632115

RS2
Small ribosomal subunit protein uS5

1

7

High-throughput

0.479

High

657278

URA7
CTP synthase 1

1

4

High-throughput

0.479

High

663457

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

681035

HS104
Heat shock protein 104

1

5

High-throughput

0.479

High

688451

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

1

High-throughput

0.479

High

691127

HOG1
Mitogen-activated protein kinase HOG1

1

8

High-throughput

0.479

High

694271

PUB1
Nuclear and cytoplasmic polyadenylated RNA-binding protein PUB1

1

20

High-throughput

0.479

High

703749

PRS6A
26S proteasome regulatory subunit 6A

1

5

High-throughput

0.479

High

713266

TSA1
Peroxiredoxin TSA1

1

5

Small-scale

0.479

High

730143

RS27A
Small ribosomal subunit protein eS27A

1

4

High-throughput

0.479

High

746550

IMB2
Importin subunit beta-2

1

8

High-throughput

0.479

High

752086

KPR3
Ribose-phosphate pyrophosphokinase 3

1

1

High-throughput

0.479

High

753965

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.479

High

755984

YHS7
Uncharacterized protein YHR127W

1

1

Small-scale

0.479

High

757035

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.479

High

757873

HRB1
Serine/arginine

1

15

Small-scale

0.479

High

761155

PCF11
Protein PCF11

1

2

Small-scale

0.479

High

774005

MLP2
Protein MLP2

1

13

High-throughput

0.479

High

774822

AIR1
Protein AIR1

1

5

Small-scale

0.479

High

785238

MPG1
Mannose-1-phosphate guanyltransferase

1

3

High-throughput

0.479

High

819882

TRF5
Poly(A) RNA polymerase protein 1

1

3

Small-scale

0.479

High

820199

RS12
Small ribosomal subunit protein eS12

1

3

High-throughput

0.479

High

860621

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

2

High-throughput

0.479

High

861258

RBG2
Ribosome-interacting GTPase 2

1

6

High-throughput

0.479

High

865624

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

8

High-throughput

0.479

High

902099

H3
Histone H3

1

8

High-throughput

0.479

High

967787

RS15
Small ribosomal subunit protein uS19

1

3

High-throughput

0.479

High

968742

MTD1
Methylenetetrahydrofolate dehydrogenase [NAD(+)]

1

3

High-throughput

0.479

High

972640

XRN2
5'-3' exoribonuclease 2

1

3

Small-scale

0.479

High

974317

ESP1
Separin

1

1

High-throughput

0.479

High

978107

CTK1
CTD kinase subunit alpha

1

12

Small-scale

0.479

High

983798

SYRC
Arginine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

986200

DCPS
m7GpppX diphosphatase

1

1

High-throughput

0.479

High

987050

TFC6
Transcription factor tau 91 kDa subunit

1

1

High-throughput

0.479

High

991405

THP1
Nuclear mRNA export protein THP1

1

3

Small-scale

0.479

High

991406

RS10A
Small ribosomal subunit protein eS10A

1

3

High-throughput

0.479

High

991409

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

1

High-throughput

0.479

High

991413

RIO1
Serine/threonine-protein kinase RIO1

1

6

High-throughput

0.479

High

991415

AHA1
Hsp90 co-chaperone AHA1

1

1

High-throughput

0.479

High

519638

ERF1
Eukaryotic peptide chain release factor subunit 1

1

0

High-throughput

0.458

High

541954

MTF1
Mitochondrial transcription factor 1

1

0

Small-scale

0.458

High

597608

CCA1
CCA tRNA nucleotidyltransferase, mitochondrial

1

0

High-throughput

0.458

High

748323

SDS24
Protein SDS24

1

0

High-throughput

0.458

High

812023

GPN1
GPN-loop GTPase 1

1

0

High-throughput

0.458

High

812510

JHD2
Histone demethylase JHD2

1

0

Small-scale

0.458

High

866098

NRK1
Nicotinamide riboside kinase

1

0

High-throughput

0.458

High

958871

GPD1
Glycerol-3-phosphate dehydrogenase [NAD(+)] 1

1

0

High-throughput

0.458

High

975585

HOT1
High-osmolarity-induced transcription protein 1

1

0

Small-scale

0.458

High

986255

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.458

High

991410

SWT1
Transcriptional protein SWT1

1

0

Small-scale

0.458

High

969225

UBC7
Ubiquitin-conjugating enzyme E2 7

1

9

High-throughput

0.457

High

478560

HSP77
Import motor subunit, mitochondrial

1

12

High-throughput

0.445

High

495085

HSP72
Heat shock protein SSA2

1

13

High-throughput

0.445

High

512913

SSB1
Ribosome-associated molecular chaperone SSB1

1

14

High-throughput

0.445

High

520001

TCPA
T-complex protein 1 subunit alpha

1

10

High-throughput

0.445

High

695636

HSP7F
Heat shock protein homolog SSE1

1

16

High-throughput

0.445

High

705715

HSP78
Heat shock protein 78, mitochondrial

1

5

High-throughput

0.445

High

744704

TAF5
Transcription initiation factor TFIID subunit 5

1

16

High-throughput

0.445

High

769601

SSB2
Ribosome-associated molecular chaperone SSB2

1

14

High-throughput

0.445

High

977530

TAF12
Transcription initiation factor TFIID subunit 12

1

3

High-throughput

0.445

High

991416

SET6
Potential protein lysine methyltransferase SET6

1

1

High-throughput

0.445

High

343153

THDH
Threonine dehydratase, mitochondrial

1

1

High-throughput

0.437

High

358283

RS17A
Small ribosomal subunit protein eS17A

1

4

High-throughput

0.437

High

471280

RS22A
Small ribosomal subunit protein uS8A

1

5

High-throughput

0.437

High

480911

RS8A
Small ribosomal subunit protein eS8A

1

5

High-throughput

0.437

High

503147

ARF1
ADP-ribosylation factor 1

1

3

High-throughput

0.437

High

594431

SAR1
Small COPII coat GTPase SAR1

1

8

High-throughput

0.437

High

706515

RS3A1
Small ribosomal subunit protein eS1A

1

7

High-throughput

0.437

High

731083

YKT6
Synaptobrevin homolog YKT6

1

1

High-throughput

0.437

High

744370

ARL1
ADP-ribosylation factor-like protein 1

1

6

High-throughput

0.437

High

762603

LAA1
AP-1 accessory protein LAA1

1

3

High-throughput

0.437

High

774673

LYS12
Homoisocitrate dehydrogenase, mitochondrial

1

3

High-throughput

0.437

High

867527

ALDH6
Magnesium-activated aldehyde dehydrogenase, cytosolic

1

2

High-throughput

0.437

High

979856

POB3
FACT complex subunit POB3

1

6

Small-scale

0.437

High

991407

AP3D
AP-3 complex subunit delta

1

2

High-throughput

0.437

High

982946

TAF9
Transcription initiation factor TFIID subunit 9

1

0

High-throughput

0.426

High

991408

HFI1
Transcriptional coactivator HFI1/ADA1

1

0

High-throughput

0.426

High

628686

CANB
Calcineurin subunit B

1

0

High-throughput

0.249

Low

690799

ERG1
Squalene epoxidase ERG1

1

0

High-throughput

0.249

Low

746560

POA1
ADP-ribose 1''-phosphate phosphatase

1

0

High-throughput

0.249

Low

863057

COPZ
Coatomer subunit zeta

1

0

High-throughput

0.249

Low

866004

YNO0
Uncharacterized protein YNL140C

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024