Protein: CDC7
Cell division control protein 7 (EC 2.7.11.1)

Gene: CDC7
Organism: Saccharomyces cerevisiae S288C
Interactions: 126
UniProt ID: P06243

Gene Ontology (top 5):
GO:0000727 - double-strand break repair via break-induced replication
GO:0000775 - chromosome, centromeric region
GO:0000785 - chromatin
GO:0001100 - negative regulation of exit from mitosis
GO:0004674 - protein serine/threonine kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

412535

DBF4
DDK kinase regulatory subunit DBF4

29

3

Small-scale

0.993

High

412496

CDC7
Cell division control protein 7

4

17

Small-scale

0.905

High

412518

RAD53
Serine/threonine-protein kinase RAD53

3

20

Small-scale

0.867

High

412539

CDC5
Cell cycle serine/threonine-protein kinase CDC5/MSD2

3

17

Small-scale

0.855

High

412529

MCM2
DNA replication licensing factor MCM2

14

20

Small-scale

0.762

High

412532

MCM4
DNA replication licensing factor MCM4

10

20

Small-scale

0.755

High

412576

MCM6
DNA replication licensing factor MCM6

7

20

Small-scale

0.744

High

409873

CDC37
Hsp90 co-chaperone Cdc37

1

20

Small-scale

0.656

High

412519

MCM3
DNA replication licensing factor MCM3

3

20

Small-scale

0.651

High

339335

CDK1
Cyclin-dependent kinase 1

1

18

Small-scale

0.647

High

365553

HSP82
ATP-dependent molecular chaperone HSP82

1

20

High-throughput

0.646

High

412520

SCJ1
DnaJ-related protein SCJ1

1

15

High-throughput

0.646

High

412522

MAS5
Mitochondrial protein import protein MAS5

1

19

High-throughput

0.646

High

412583

ACT
Actin

1

14

High-throughput

0.646

High

412530

MCM5
Minichromosome maintenance protein 5

2

20

Small-scale

0.625

High

412553

RT107
Regulator of Ty1 transposition protein 107

2

4

Small-scale

0.620

High

412502

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

1

20

High-throughput

0.618

High

412538

HOG1
Mitogen-activated protein kinase HOG1

1

19

Small-scale

0.618

High

412536

MCM10
Minichromosome maintenance protein 10

2

4

Small-scale

0.602

High

412607

RLF2
Chromatin assembly factor 1 subunit p90

2

10

Small-scale

0.602

High

412598

CDC53
Cell division control protein 53

2

19

Small-scale

0.595

High

412549

MCM7
DNA replication licensing factor MCM7

2

20

Small-scale

0.594

High

412585

PRS8
26S proteasome regulatory subunit 8 homolog

2

20

Small-scale

0.584

High

412540

RPN2
26S proteasome regulatory subunit RPN2

1

11

Small-scale

0.575

High

412548

CENPA
Histone H3-like centromeric protein CSE4

1

20

Small-scale

0.561

High

412567

MSH4
MutS protein homolog 4

1

6

Small-scale

0.561

High

412556

REV7
DNA polymerase zeta processivity subunit

1

0

Small-scale

0.537

High

412513

PDC5
Pyruvate decarboxylase isozyme 2

1

5

High-throughput

0.536

High

412526

PDC6
Pyruvate decarboxylase isozyme 3

1

5

High-throughput

0.536

High

412527

RPAC2
DNA-directed RNA polymerases I and III subunit RPAC2

1

2

High-throughput

0.536

High

412558

HSP7E
Heat shock protein SSC3, mitochondrial

1

20

High-throughput

0.536

High

412589

KYNU
Kynureninase

1

1

High-throughput

0.536

High

412595

THI3
Thiamine metabolism regulatory protein THI3

1

5

High-throughput

0.536

High

412588

LRS4
Monopolin complex subunit LRS4

1

1

Small-scale

0.515

High

412537

HYM1
Protein HYM1

1

1

Small-scale

0.514

High

412586

CENPP
Inner kinetochore subunit CTF19

1

0

Small-scale

0.513

High

412574

BIR1
Protein BIR1

1

0

High-throughput

0.513

High

412577

MED5
Mediator of RNA polymerase II transcription subunit 5

1

0

High-throughput

0.513

High

412557

DHH1
ATP-dependent RNA helicase DHH1

1

20

High-throughput

0.508

High

412533

ZIP1
Synaptonemal complex protein ZIP1

1

20

Small-scale

0.501

High

412546

SLD2
DNA replication regulator SLD2

1

2

Small-scale

0.501

High

412547

CENPC
Inner kinetochore subunit MIF2

1

1

Small-scale

0.501

High

412561

RT106
Histone chaperone RTT106

1

1

Small-scale

0.501

High

412570

ECO1
N-acetyltransferase ECO1

1

2

Small-scale

0.501

High

412572

COM1
DNA endonuclease SAE2

1

1

Small-scale

0.501

High

412573

EAF6
Chromatin modification-related protein EAF6

1

2

High-throughput

0.501

High

341866

ATPB
ATP synthase subunit beta, mitochondrial

1

13

High-throughput

0.500

High

360685

TBB
Tubulin beta chain

1

20

High-throughput

0.500

High

381398

GAL1
Galactokinase

1

2

High-throughput

0.500

High

412497

ATPA
ATP synthase subunit alpha, mitochondrial

1

14

High-throughput

0.500

High

412499

TBA1
Tubulin alpha-1 chain

1

15

High-throughput

0.500

High

412500

TBA3
Tubulin alpha-3 chain

1

19

High-throughput

0.500

High

412512

VATB
V-type proton ATPase subunit B

1

14

High-throughput

0.500

High

412515

PFKA2
ATP-dependent 6-phosphofructokinase subunit beta

1

6

High-throughput

0.500

High

412516

HSP60
Heat shock protein 60, mitochondrial

1

20

High-throughput

0.500

High

412525

CDC48
Cell division control protein 48

1

8

High-throughput

0.500

High

412596

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

1

High-throughput

0.500

High

412597

THI21
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI21

1

1

High-throughput

0.500

High

412606

RUVB2
RuvB-like protein 2

1

8

High-throughput

0.500

High

412511

STI1
Heat shock protein STI1

1

16

High-throughput

0.489

High

412517

SAR1
Small COPII coat GTPase SAR1

1

11

High-throughput

0.489

High

412568

COPB2
Coatomer subunit beta'

1

10

High-throughput

0.489

High

412584

TPS1
Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 56 kDa subunit

1

6

High-throughput

0.489

High

412592

BFR2
Protein BFR2

1

1

High-throughput

0.489

High

412604

PST2
Protoplast secreted protein 2

1

3

High-throughput

0.489

High

412575

TEL2
Telomere length regulation protein TEL2

1

0

High-throughput

0.486

High

412600

TSR3
18S rRNA aminocarboxypropyltransferase

1

0

High-throughput

0.486

High

412541

ORC2
Origin recognition complex subunit 2

1

7

Small-scale

0.481

High

412531

RIF1
Telomere length regulator protein RIF1

1

0

Small-scale

0.480

High

412593

CENPO
Inner kinetochore subunit MCM21

1

0

Small-scale

0.480

High

412608

CENPI
Inner kinetochore subunit CTF3

1

0

Small-scale

0.480

High

412528

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.479

High

412550

MMS4
Crossover junction endonuclease MMS4

1

1

Small-scale

0.479

High

412566

DSN1
Kinetochore-associated protein DSN1

1

1

High-throughput

0.479

High

412578

NMA2
Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 2

1

1

High-throughput

0.479

High

412581

NAT10
RNA cytidine acetyltransferase

1

2

High-throughput

0.479

High

412587

SCC2
Sister chromatid cohesion protein 2

1

4

High-throughput

0.479

High

412599

MLH3
DNA mismatch repair protein MLH3

1

2

High-throughput

0.479

High

412590

CORO
Coronin-like protein

1

7

High-throughput

0.470

High

397559

OTC
Ornithine carbamoyltransferase

1

7

High-throughput

0.464

High

412564

SPO22
Sporulation-specific protein 22

1

0

Small-scale

0.458

High

412582

ORC3
Origin recognition complex subunit 3

1

0

Small-scale

0.458

High

412591

NOC4
Nucleolar complex protein 4

1

0

Small-scale

0.458

High

412562

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

14

High-throughput

0.457

High

367600

EF1A
Elongation factor 1-alpha

1

8

High-throughput

0.457

High

378253

LEU3
3-isopropylmalate dehydrogenase

1

12

High-throughput

0.457

High

412508

ODP2
Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial

1

4

High-throughput

0.457

High

412603

HSP42
Heat shock protein 42

1

3

High-throughput

0.457

High

412503

HSP77
Import motor subunit, mitochondrial

1

20

High-throughput

0.445

High

412504

IF4A
ATP-dependent RNA helicase eIF4A

1

20

Small-scale

0.445

High

412505

HSP71
Heat shock protein SSA1

1

20

High-throughput

0.445

High

412507

SSB1
Ribosome-associated molecular chaperone SSB1

1

20

High-throughput

0.445

High

412510

PP2B2
Serine/threonine-protein phosphatase 2B catalytic subunit A2

1

20

Small-scale

0.445

High

412514

BIP
Endoplasmic reticulum chaperone BiP

1

20

Small-scale

0.445

High

412543

PRS6A
26S proteasome regulatory subunit 6A

1

20

Small-scale

0.445

High

412544

PRS6B
26S proteasome regulatory subunit 6B homolog

1

17

Small-scale

0.445

High

412545

PRS7
26S proteasome regulatory subunit 7 homolog

1

20

Small-scale

0.445

High

412552

RPN1
26S proteasome regulatory subunit RPN1

1

12

Small-scale

0.445

High

412560

SSB2
Ribosome-associated molecular chaperone SSB2

1

20

High-throughput

0.445

High

412563

PRS4
26S proteasome regulatory subunit 4 homolog

1

20

Small-scale

0.445

High

412579

PRS10
26S proteasome subunit RPT4

1

20

Small-scale

0.445

High

141811

RPN13
26S proteasome regulatory subunit RPN13

1

0

Small-scale

0.426

High

412554

SSP1
Sporulation-specific protein 1

1

0

Small-scale

0.426

High

412555

ADY1
Prospore formation at selected spindle poles protein 1

1

0

Small-scale

0.426

High

412601

REC8
Meiotic recombination protein REC8

1

0

Small-scale

0.426

High

412605

MPC70
Sporulation-specific protein 21

1

0

Small-scale

0.426

High

412498

SPS2
Sporulation-specific protein 2

1

1

Small-scale

0.407

High

412506

ARF1
ADP-ribosylation factor 1

1

7

Small-scale

0.407

High

412509

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

4

Small-scale

0.407

High

412521

SPS22
Sporulation-specific protein 22

1

1

Small-scale

0.407

High

412551

SDS24
Protein SDS24

1

3

Small-scale

0.407

High

412569

SPR3
Sporulation-regulated protein 3

1

4

Small-scale

0.407

High

412594

VAC14
Vacuole morphology and inheritance protein 14

1

0

High-throughput

0.279

Low

412524

YCU0
Uncharacterized protein YCR050C

1

0

High-throughput

0.265

Low

412542

PTM1
Membrane protein PTM1

1

0

High-throughput

0.265

Low

412559

YEC3
Uncharacterized protein YEL023C

1

0

High-throughput

0.265

Low

412571

YFM7
Uncharacterized protein YFR057W

1

0

High-throughput

0.265

Low

412580

YN8S
Phospholipid-transporting ATPase accessory subunit CRF1

1

0

High-throughput

0.265

Low

141793

JIP3
Uncharacterized protein JIP3

1

0

High-throughput

0.261

Low

412609

EFG1P
rRNA-processing protein EFG1

1

0

High-throughput

0.249

Low

412523

YCR2
Uncharacterized protein YCR022C

1

0

High-throughput

0.238

Low

412501

SPS4
Sporulation-specific protein 4

1

0

Small-scale

0.232

Low

412534

LDS1
Outer spore wall protein LDS1

1

0

Small-scale

0.232

Low

412565

GVP36
Protein GVP36

1

0

Small-scale

0.232

Low

412602

YO214
Cell wall protein YOR214C

1

0

Small-scale

0.232

Low


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Last updated: 15 Jul 2024