Protein: SEC18
Vesicular-fusion protein SEC18

Gene: SEC18
Organism: Saccharomyces cerevisiae S288C
Interactions: 106
UniProt ID: P18759

Gene Ontology (top 5):
GO:0000045 - autophagosome assembly
GO:0000149 - SNARE binding
GO:0005524 - ATP binding
GO:0005794 - Golgi apparatus
GO:0005795 - Golgi stack

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

578498

SEC18
Vesicular-fusion protein SEC18

2

19

Small-scale

0.781

High

578513

HS104
Heat shock protein 104

2

4

High-throughput

0.754

High

578518

SEC17
Alpha-soluble NSF attachment protein

4

9

Small-scale

0.683

High

578533

RPN1
26S proteasome regulatory subunit RPN1

2

4

High-throughput

0.675

High

578546

COPB2
Coatomer subunit beta'

3

5

High-throughput

0.670

High

578548

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

3

8

High-throughput

0.640

High

578522

PRS7
26S proteasome regulatory subunit 7 homolog

1

17

High-throughput

0.618

High

578542

PRS4
26S proteasome regulatory subunit 4 homolog

1

10

High-throughput

0.618

High

578551

PRS10
26S proteasome subunit RPT4

1

20

High-throughput

0.618

High

578564

RUVB1
RuvB-like protein 1

1

4

High-throughput

0.618

High

578565

RPN9
26S proteasome regulatory subunit RPN9

2

2

High-throughput

0.601

High

578500

TRX1
Thioredoxin-1

2

4

Small-scale

0.595

High

578578

VAM3
Syntaxin VAM3

2

14

Small-scale

0.595

High

578545

MAD2
Mitotic spindle checkpoint component MAD2

1

1

High-throughput

0.587

High

543151

HSC82
ATP-dependent molecular chaperone HSC82

2

8

High-throughput

0.584

High

578499

SEC22
Protein transport protein SEC22

2

6

Small-scale

0.584

High

578528

YKT6
Synaptobrevin homolog YKT6

2

6

Small-scale

0.584

High

578534

RPN10
26S proteasome regulatory subunit RPN10

2

2

High-throughput

0.584

High

578507

MAS5
Mitochondrial protein import protein MAS5

2

5

High-throughput

0.571

High

578504

PSA2
Proteasome subunit alpha type-2

1

11

High-throughput

0.553

High

578567

RPN7
26S proteasome regulatory subunit RPN7

1

2

High-throughput

0.553

High

578579

RPN5
26S proteasome regulatory subunit RPN5

2

4

High-throughput

0.549

High

578529

ATG12
Ubiquitin-like protein ATG12

1

1

High-throughput

0.536

High

578550

BUD32
EKC/KEOPS complex subunit BUD32

1

1

High-throughput

0.536

High

578563

GCN5
Histone acetyltransferase GCN5

1

10

High-throughput

0.536

High

578515

EI2BB
Translation initiation factor eIF2B subunit beta

1

2

High-throughput

0.508

High

578558

IMA1
Importin subunit alpha

1

2

High-throughput

0.508

High

578502

TRX2
Thioredoxin-2

1

3

Small-scale

0.501

High

578521

VAM7
Vacuolar morphogenesis protein 7

1

3

Small-scale

0.501

High

294089

SEM1
26S proteasome complex subunit SEM1

1

0

High-throughput

0.493

High

578524

SPT7
Transcriptional activator SPT7

1

6

High-throughput

0.489

High

578530

NTM1
Alpha N-terminal protein methyltransferase 1

1

0

High-throughput

0.486

High

578559

MUK1
Protein MUK1

1

0

High-throughput

0.486

High

478656

IPB2
Protease B inhibitor 2

1

0

Small-scale

0.480

High

357867

RS17A
Small ribosomal subunit protein eS17A

1

2

High-throughput

0.479

High

365755

HSP82
ATP-dependent molecular chaperone HSP82

1

8

High-throughput

0.479

High

382937

RL25
Large ribosomal subunit protein uL23

1

2

High-throughput

0.479

High

405414

RL26A
Large ribosomal subunit protein uL24A

1

2

High-throughput

0.479

High

406761

RS3
Small ribosomal subunit protein uS3

1

2

High-throughput

0.479

High

407709

RS13
Small ribosomal subunit protein uS15

1

3

High-throughput

0.479

High

425746

RS19A
Small ribosomal subunit protein eS19A

1

1

High-throughput

0.479

High

470847

RS22A
Small ribosomal subunit protein uS8A

1

1

High-throughput

0.479

High

472004

RL31A
Large ribosomal subunit protein eL31A

1

2

High-throughput

0.479

High

482066

RS18A
Small ribosomal subunit protein uS13A

1

2

High-throughput

0.479

High

485634

IF4A
ATP-dependent RNA helicase eIF4A

1

5

High-throughput

0.479

High

578501

VPS34
Phosphatidylinositol 3-kinase VPS34

1

6

High-throughput

0.479

High

578503

BET1
Protein transport protein BET1

1

6

Small-scale

0.479

High

578505

SIS1
Protein SIS1

1

6

High-throughput

0.479

High

578508

RS7A
Small ribosomal subunit protein eS7A

1

3

High-throughput

0.479

High

578511

SEC1
Protein transport protein SEC1

1

4

High-throughput

0.479

High

578512

SNC1
Synaptobrevin homolog 1

1

8

Small-scale

0.479

High

578514

RPN12
26S proteasome regulatory subunit RPN12

1

1

High-throughput

0.479

High

578519

PEP12
Syntaxin PEP12

1

17

Small-scale

0.479

High

578520

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

578523

RS3A1
Small ribosomal subunit protein eS1A

1

2

High-throughput

0.479

High

578527

RS27A
Small ribosomal subunit protein eS27A

1

3

High-throughput

0.479

High

578531

RS20
Small ribosomal subunit protein uS10

1

1

High-throughput

0.479

High

578538

LAA1
AP-1 accessory protein LAA1

1

2

High-throughput

0.479

High

578544

SEC24
Protein transport protein SEC24

1

3

High-throughput

0.479

High

578549

UBC9
SUMO-conjugating enzyme UBC9

1

3

High-throughput

0.479

High

578553

PPID
Peptidyl-prolyl cis-trans isomerase CPR6

1

2

High-throughput

0.479

High

578556

SED5
Integral membrane protein SED5

1

17

Small-scale

0.479

High

578557

RS15
Small ribosomal subunit protein uS19

1

1

High-throughput

0.479

High

578560

BECN1
Vacuolar protein sorting-associated protein 30

1

2

High-throughput

0.479

High

578566

SYRC
Arginine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.479

High

578570

SUB2
ATP-dependent RNA helicase SUB2

1

2

High-throughput

0.479

High

578572

RS10A
Small ribosomal subunit protein eS10A

1

5

High-throughput

0.479

High

578573

AP3D
AP-3 complex subunit delta

1

8

High-throughput

0.479

High

578574

MLH3
DNA mismatch repair protein MLH3

1

2

High-throughput

0.479

High

578575

ATG9
Autophagy-related protein 9

1

2

High-throughput

0.479

High

578576

RIO1
Serine/threonine-protein kinase RIO1

1

1

High-throughput

0.479

High

578536

MET30
F-box protein MET30

1

9

High-throughput

0.464

High

578554

CAF40
Protein CAF40

1

2

High-throughput

0.464

High

578506

BOS1
Protein transport protein BOS1

1

0

Small-scale

0.458

High

578543

SEC9
Protein transport protein SEC9

1

0

High-throughput

0.458

High

578552

MSO1
Protein MSO1

1

0

High-throughput

0.458

High

578581

AHA1
Hsp90 co-chaperone AHA1

1

0

High-throughput

0.458

High

493147

HSP72
Heat shock protein SSA2

1

7

High-throughput

0.445

High

578517

HSP7F
Heat shock protein homolog SSE1

1

13

High-throughput

0.445

High

578541

SSB2
Ribosome-associated molecular chaperone SSB2

1

7

High-throughput

0.445

High

355336

H2B1
Histone H2B.1

1

4

High-throughput

0.437

High

355767

H2B2
Histone H2B.2

1

4

High-throughput

0.437

High

392047

H2A1
Histone H2A.1

1

4

High-throughput

0.437

High

392281

H2A2
Histone H2A.2

1

4

High-throughput

0.437

High

578510

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.437

High

578516

RPN2
26S proteasome regulatory subunit RPN2

1

4

High-throughput

0.437

High

578532

ECM29
Proteasome component ECM29

1

4

High-throughput

0.437

High

578539

RPN3
26S proteasome regulatory subunit RPN3

1

4

High-throughput

0.437

High

578547

UFE1
Syntaxin UFE1

1

1

High-throughput

0.437

High

578555

H3
Histone H3

1

6

High-throughput

0.437

High

578561

ESP1
Separin

1

1

High-throughput

0.437

High

578562

TOM1
E3 ubiquitin-protein ligase TOM1

1

6

High-throughput

0.437

High

578568

TFC6
Transcription factor tau 91 kDa subunit

1

1

High-throughput

0.437

High

578569

ATG23
Autophagy-related protein 23

1

1

High-throughput

0.437

High

578571

RPN8
26S proteasome regulatory subunit RPN8

1

1

High-throughput

0.437

High

578577

SIZ2
E3 SUMO-protein ligase SIZ2

1

1

High-throughput

0.437

High

578580

RPN6
26S proteasome regulatory subunit RPN6

1

1

High-throughput

0.437

High

578582

CMR1
DNA damage-binding protein CMR1

1

5

High-throughput

0.437

High

578535

SPT8
Transcription factor SPT8

1

1

High-throughput

0.407

High

578540

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

6

High-throughput

0.407

High

141822

RPN13
26S proteasome regulatory subunit RPN13

1

0

High-throughput

0.249

Low

578509

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.249

Low

578525

SPT10
Protein SPT10

1

0

High-throughput

0.249

Low

578526

SPT21
Protein SPT21

1

0

High-throughput

0.249

Low

578537

YM11
Uncharacterized protein YMR124W

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024