Protein: SIN3A
Paired amphipathic helix protein Sin3a (Histone deacetylase complex subunit Sin3a) (Transcriptional corepressor Sin3a)

Gene: SIN3A
Organism: Mus musculus
Interactions: 52
UniProt ID: Q60520

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000776 - kinetochore
GO:0001701 - in utero embryonic development
GO:0002218 - activation of innate immune response
GO:0002230 - positive regulation of defense response to virus by host

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

148692

HDAC1
Histone deacetylase 1

10

17

Small-scale

0.970

High

1000006

HDAC2
Histone deacetylase 2

5

18

Small-scale

0.909

High

1221132

SDS3
Sin3 histone deacetylase corepressor complex component SDS3

2

9

Small-scale

0.786

High

312639

SAP30
Histone deacetylase complex subunit SAP30

1

4

Small-scale

0.700

High

1221128

KDM5B
Lysine-specific demethylase 5B

1

2

Small-scale

0.691

High

1221146

MECP2
Methyl-CpG-binding protein 2

3

6

Small-scale

0.656

High

1168627

SAP25
Histone deacetylase complex subunit SAP25

1

2

Small-scale

0.653

High

872991

SOX2
Transcription factor SOX-2

2

8

Small-scale

0.621

High

1221126

SIN3B
Paired amphipathic helix protein Sin3b

1

3

Small-scale

0.618

High

1221129

NANOG
Homeobox protein NANOG

2

2

Small-scale

0.611

High

1221138

GON4L
GON-4-like protein

1

0

Small-scale

0.586

High

644326

TAL1
T-cell acute lymphocytic leukemia protein 1 homolog

2

2

Small-scale

0.584

High

1190544

Q3UM65
Runt-related transcription factor

2

1

Small-scale

0.584

High

1190615

TF2L1
Transcription factor CP2-like protein 1

1

1

High-throughput

0.536

High

60008

ARI1A
AT-rich interactive domain-containing protein 1A

1

1

Small-scale

0.515

High

604518

SPI1
Transcription factor PU.1

1

5

Small-scale

0.515

High

1190805

TET1
Methylcytosine dioxygenase TET1

1

3

Small-scale

0.515

High

896180

MAD1
Max dimerization protein 1

1

17

Small-scale

0.506

High

896217

MXI1
Max-interacting protein 1

1

17

Small-scale

0.506

High

700397

CEBPB
CCAAT/enhancer-binding protein beta

1

5

Small-scale

0.501

High

1221139

Q9JIZ5
Activator protein 4

1

2

Small-scale

0.501

High

1221141

KLF13
Krueppel-like factor 13

1

7

Small-scale

0.501

High

1221144

SRBP1
Sterol regulatory element-binding protein 1

1

1

Small-scale

0.501

High

1221125

Q60I23
SRY

1

8

High-throughput

0.484

High

382479

P53
Cellular tumor antigen p53

1

2

High-throughput

0.481

High

1221140

DDX20
Probable ATP-dependent RNA helicase DDX20

1

0

Small-scale

0.480

High

148317

MNT
Max-binding protein MNT

1

20

Small-scale

0.479

High

205749

PER1
Period circadian protein homolog 1

1

3

Small-scale

0.479

High

236753

PER2
Period circadian protein homolog 2

1

3

Small-scale

0.479

High

267162

SP3
Transcription factor Sp3

1

13

Small-scale

0.479

High

703230

APEX1
DNA repair nuclease/redox regulator APEX1

1

1

Small-scale

0.479

High

921251

CEBPA
CCAAT/enhancer-binding protein alpha

1

4

Small-scale

0.479

High

1021228

ETV6
Transcription factor ETV6

1

4

Small-scale

0.479

High

1021501

SMAD4
Mothers against decapentaplegic homolog 4

1

1

Small-scale

0.479

High

1194875

TET2
Methylcytosine dioxygenase TET2

1

3

Small-scale

0.479

High

1221124

NCOR1
Nuclear receptor corepressor 1

1

7

Small-scale

0.479

High

1221133

P66A
Transcriptional repressor p66 alpha

1

5

Small-scale

0.479

High

1221135

ELF5
ETS-related transcription factor Elf-5

1

3

High-throughput

0.479

High

1221136

SFPQ
Splicing factor, proline- and glutamine-rich

1

2

Small-scale

0.479

High

1221137

Q91VN7
Max dimerization protein 4

1

18

Small-scale

0.479

High

1221143

DACH1
Dachshund homolog 1

1

1

Small-scale

0.479

High

947431

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

0

Small-scale

0.458

High

1027936

TYY1
Transcriptional repressor protein YY1

1

0

Small-scale

0.458

High

1221142

CAF1A
Chromatin assembly factor 1 subunit A

1

0

High-throughput

0.458

High

1221145

SUFU
Suppressor of fused homolog

1

0

Small-scale

0.458

High

1221127

Q6AXH7
Histone-lysine N-methyltransferase EZH2

1

4

High-throughput

0.445

High

1221130

Q8BK32
Nuclear receptor co-repressor 1

1

3

Small-scale

0.439

High

358028

CP1A1
Cytochrome P450 1A1

1

1

Small-scale

0.437

High

1221131

BICD1
Protein bicaudal D homolog 1

1

1

High-throughput

0.407

High

398447

CFAD
Complement factor D

1

0

High-throughput

0.249

Low

441583

CD4
T-cell surface glycoprotein CD4

1

0

Small-scale

0.249

Low

1221134

FNDC5
Fibronectin type III domain-containing protein 5

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025