Protein: STE50
Protein STE50

Gene: STE50
Organism: Saccharomyces cerevisiae S288C
Interactions: 134
UniProt ID: P25344

Gene Ontology (top 5):
GO:0000750 - pheromone-dependent signal transduction involved in conjugation with cellular fusion
GO:0001402 - signal transduction involved in filamentous growth
GO:0005737 - cytoplasm
GO:0007049 - cell cycle
GO:0007232 - osmosensory signaling pathway via Sho1 osmosensor

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

629685

STE50
Protein STE50

3

1

Small-scale

0.850

High

618311

STE11
Serine/threonine-protein kinase STE11

27

1

Small-scale

0.769

High

629782

OPY2
Protein OPY2

5

0

Small-scale

0.692

High

629752

RHO5
GTP-binding protein RHO5

1

1

Small-scale

0.647

High

629720

GIC1
GTPase-interacting component 1

3

1

High-throughput

0.639

High

629730

SHO1
High osmolarity signaling protein SHO1

3

0

Small-scale

0.636

High

629779

ATG17
Autophagy-related protein 17

2

0

High-throughput

0.587

High

580297

CDC42
Cell division control protein 42

1

0

Small-scale

0.586

High

629781

GIC2
GTPase-interacting component 2

3

1

High-throughput

0.583

High

419743

RHO2
GTP-binding protein RHO2

1

1

Small-scale

0.579

High

629758

RHO3
GTP-binding protein RHO3

1

1

Small-scale

0.579

High

629703

STE5
Protein STE5

2

0

Small-scale

0.577

High

490437

HSP71
Heat shock protein SSA1

2

1

High-throughput

0.576

High

493281

HSP72
Heat shock protein SSA2

2

1

High-throughput

0.576

High

579402

GBB
Guanine nucleotide-binding protein subunit beta

2

0

Small-scale

0.559

High

629753

CBK1
Serine/threonine-protein kinase CBK1

2

0

Small-scale

0.559

High

629714

AKL1
Serine/threonine-protein kinase AKL1

2

0

High-throughput

0.551

High

629686

RHEB
Rheb-like protein RHB1

1

0

Small-scale

0.541

High

425305

PHO4
Phosphate system positive regulatory protein PHO4

1

0

High-throughput

0.513

High

629694

XPO1
Exportin-1

1

0

High-throughput

0.513

High

629718

RIM11
Serine/threonine-protein kinase RIM11/MSD1

1

1

Small-scale

0.501

High

622857

DPB2
DNA polymerase epsilon subunit B

1

0

High-throughput

0.493

High

629719

RIM4
Meiotic activator RIM4

1

0

High-throughput

0.493

High

629747

ARI1
NADPH-dependent aldehyde reductase ARI1

1

0

High-throughput

0.493

High

629791

PST2
Protoplast secreted protein 2

1

0

High-throughput

0.486

High

629732

TBP6
Probable 26S proteasome subunit YTA6

1

1

High-throughput

0.481

High

629697

HOG1
Mitogen-activated protein kinase HOG1

1

0

Small-scale

0.480

High

629790

GIN4
Serine/threonine-protein kinase GIN4

1

0

Small-scale

0.480

High

145902

YO304
Uncharacterized protein YOR304C-A

1

0

High-throughput

0.460

High

430751

SYV
Valine--tRNA ligase, mitochondrial

1

0

High-throughput

0.460

High

446117

MYO1
Myosin-1

1

0

High-throughput

0.460

High

629696

SP110
Spindle pole body component 110

1

0

High-throughput

0.460

High

629705

SPC29
Spindle pole component 29

1

0

High-throughput

0.460

High

629710

DYHC
Dynein heavy chain, cytoplasmic

1

0

High-throughput

0.460

High

629713

DAD2
DASH complex subunit DAD2

1

0

High-throughput

0.460

High

629716

FL2D
Protein MUM2

1

0

High-throughput

0.460

High

629723

END3
Actin cytoskeleton-regulatory complex protein END3

1

0

High-throughput

0.460

High

629728

VAB2
Biogenesis of lysosome-related organelles complex 1 subunit VAB2

1

0

High-throughput

0.460

High

629736

FAR3
Factor arrest protein 3

1

0

High-throughput

0.460

High

629737

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.460

High

629738

VPS53
Vacuolar protein sorting-associated protein 53

1

0

High-throughput

0.460

High

629739

MPS3
Spindle pole body assembly component MPS3

1

0

High-throughput

0.460

High

629745

PSP1
Protein PSP1

1

0

High-throughput

0.460

High

629756

HSK3
DASH complex subunit HSK3

1

0

High-throughput

0.460

High

629760

MDM1
Structural protein MDM1

1

0

High-throughput

0.460

High

629772

VPS20
Vacuolar protein sorting-associated protein 20

1

0

High-throughput

0.460

High

629783

VAM6
Vacuolar morphogenesis protein 6

1

0

High-throughput

0.460

High

629792

GYP5
GTPase-activating protein GYP5

1

0

High-throughput

0.460

High

629793

SKS1
Serine/threonine-protein kinase SKS1

1

0

High-throughput

0.460

High

543260

HSC82
ATP-dependent molecular chaperone HSC82

1

0

High-throughput

0.458

High

629704

HSP78
Heat shock protein 78, mitochondrial

1

0

High-throughput

0.458

High

629727

SAP1
Protein SAP1

1

1

High-throughput

0.457

High

629699

HSP7F
Heat shock protein homolog SSE1

1

2

High-throughput

0.445

High

629746

MGA1
Protein MGA1

1

1

High-throughput

0.439

High

629759

SED5
Integral membrane protein SED5

1

1

High-throughput

0.439

High

629764

TLG1
t-SNARE affecting a late Golgi compartment protein 1

1

1

High-throughput

0.439

High

629689

AHC2
ADA histone acetyltransferase complex component 2

1

0

High-throughput

0.438

High

629749

DAM1
DASH complex subunit DAM1

1

0

Small-scale

0.438

High

629755

RUXF
Small nuclear ribonucleoprotein F

1

0

High-throughput

0.438

High

629763

BECN1
Vacuolar protein sorting-associated protein 30

1

0

High-throughput

0.438

High

629780

HPA2
Histone acetyltransferase HPA2

1

0

High-throughput

0.438

High

629784

ADY3
Accumulates dyads protein 3

1

0

High-throughput

0.438

High

629795

HRP1
Nuclear polyadenylated RNA-binding protein 4

1

0

High-throughput

0.438

High

510368

SSB1
Ribosome-associated molecular chaperone SSB1

1

0

High-throughput

0.426

High

554567

HSP26
Heat shock protein 26

1

0

High-throughput

0.426

High

629773

SPC24
Kinetochore protein SPC24

2

0

Small-scale

0.310

High

629691

DPB3
DNA polymerase epsilon subunit C

1

0

High-throughput

0.269

Low

629717

MBA1
Inner membrane mitoribosome receptor MBA1, mitochondrial

1

0

High-throughput

0.269

Low

629748

ITC1
Imitation switch two complex protein 1

1

0

High-throughput

0.269

Low

614560

KC11
Casein kinase I homolog 1

1

0

Small-scale

0.261

Low

404044

ATPF
ATP synthase subunit 4, mitochondrial

1

0

High-throughput

0.251

Low

424948

GCR1
Glycolytic genes transcriptional activator GCR1

1

0

High-throughput

0.251

Low

599895

RE107
Recombination protein 107

1

0

High-throughput

0.251

Low

603278

SNF2
Transcription regulatory protein SNF2

1

0

High-throughput

0.251

Low

629687

BOS1
Protein transport protein BOS1

1

0

High-throughput

0.251

Low

629688

SGF29
SAGA-associated factor 29

1

0

High-throughput

0.251

Low

629690

MSH1
DNA mismatch repair protein MSH1, mitochondrial

1

0

High-throughput

0.251

Low

629695

ATP7
ATP synthase subunit d, mitochondrial

1

0

High-throughput

0.251

Low

629702

VAM7
Vacuolar morphogenesis protein 7

1

0

High-throughput

0.251

Low

629706

NIP80
Protein NIP100

1

0

High-throughput

0.251

Low

629707

SCD5
Protein SCD5

1

0

High-throughput

0.251

Low

629709

YKF0
Uncharacterized protein YKL050C

1

0

High-throughput

0.251

Low

629711

EBP2
rRNA-processing protein EBP2

1

0

High-throughput

0.251

Low

629715

QDR3
Quinidine resistance protein 3

1

0

High-throughput

0.251

Low

629721

LAM4
Membrane-anchored lipid-binding protein LAM4

1

0

High-throughput

0.251

Low

629722

SKN7
Transcription factor SKN7

1

0

High-throughput

0.251

Low

629725

LAA1
AP-1 accessory protein LAA1

1

0

High-throughput

0.251

Low

629729

SPC25
Kinetochore protein SPC25

1

0

High-throughput

0.251

Low

629731

NACB2
Nascent polypeptide-associated complex subunit beta-2

1

0

High-throughput

0.251

Low

629733

ATAD2
ATPase histone chaperone YTA7

1

0

High-throughput

0.251

Low

629734

CBF3B
Centromere DNA-binding protein complex CBF3 subunit B

1

0

High-throughput

0.251

Low

629740

EAF6
Chromatin modification-related protein EAF6

1

0

High-throughput

0.251

Low

629743

CCM1
Mitochondrial 15S rRNA processing factor CCM1

1

0

High-throughput

0.251

Low

629744

KEL2
Kelch repeat-containing protein 2

1

0

High-throughput

0.251

Low

629751

RM50
Large ribosomal subunit protein bL9m

1

0

High-throughput

0.251

Low

629757

CTR9
RNA polymerase-associated protein CTR9

1

0

High-throughput

0.251

Low

629762

LGE1
Transcriptional regulatory protein LGE1

1

0

High-throughput

0.251

Low

629766

RCF1
Respiratory supercomplex factor 1, mitochondrial

1

0

High-throughput

0.251

Low

629767

YAP6
AP-1-like transcription factor YAP6

1

0

High-throughput

0.251

Low

629768

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.251

Low

629770

LRS4
Monopolin complex subunit LRS4

1

0

High-throughput

0.251

Low

629774

IVY1
Protein IVY1

1

0

High-throughput

0.251

Low

629775

ENT2
Epsin-2

1

0

High-throughput

0.251

Low

629776

NKP2
Inner kinetochore subunit NKP2

1

0

High-throughput

0.251

Low

629778

VTA1
Vacuolar protein sorting-associated protein VTA1

1

0

High-throughput

0.251

Low

629787

DSC3
DSC E3 ubiquitin ligase complex subunit 3

1

0

High-throughput

0.251

Low

629789

CENPH
Inner kinetochore subunit MCM16

1

0

High-throughput

0.251

Low

629794

NOP14
Nucleolar complex protein 14

1

0

High-throughput

0.251

Low

629692

HIBCH
Small ribosomal subunit protein mS47

1

0

High-throughput

0.249

Low

629693

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.249

Low

629777

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

0

High-throughput

0.249

Low

141907

YP076
Putative uncharacterized protein YPR076W

1

0

High-throughput

0.238

Low

577290

GLN3
Nitrogen regulatory protein GLN3

1

0

High-throughput

0.238

Low

606315

SEC15
Exocyst complex component SEC15

1

0

High-throughput

0.238

Low

629698

VPP1
V-type proton ATPase subunit a, vacuolar isoform

1

0

High-throughput

0.238

Low

629700

VATD
V-type proton ATPase subunit D

1

0

High-throughput

0.238

Low

629701

PEP12
Syntaxin PEP12

1

0

High-throughput

0.238

Low

629708

BLI1
Biogenesis of lysosome-related organelles complex 1 subunit BLI1

1

0

High-throughput

0.238

Low

629712

VPS51
Vacuolar protein sorting-associated protein 51

1

0

High-throughput

0.238

Low

629724

IFH1
Protein IFH1

1

0

High-throughput

0.238

Low

629726

MBO1
Gamma tubulin complex adapter SPC72

1

0

High-throughput

0.238

Low

629735

FIP1
Pre-mRNA polyadenylation factor FIP1

1

0

High-throughput

0.238

Low

629741

MED21
Mediator of RNA polymerase II transcription subunit 21

1

0

High-throughput

0.238

Low

629742

SNAPN
Biogenesis of lysosome-related organelles complex 1 subunit SNN1

1

0

High-throughput

0.238

Low

629750

RRN9
RNA polymerase I-specific transcription initiation factor RRN9

1

0

High-throughput

0.238

Low

629754

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.238

Low

629761

UBC7
Ubiquitin-conjugating enzyme E2 7

1

0

High-throughput

0.238

Low

629765

NAA30
N-alpha-acetyltransferase 30

1

0

High-throughput

0.238

Low

629769

SYF1
Pre-mRNA-splicing factor SYF1

1

0

High-throughput

0.238

Low

629771

MUS81
Crossover junction endonuclease MUS81

1

0

High-throughput

0.238

Low

629785

LDB18
Protein LDB18

1

0

High-throughput

0.238

Low

629786

NTH2
Endonuclease III homolog 2

1

0

High-throughput

0.238

Low

629788

YD016
Putative uncharacterized protein YDL016C

1

0

High-throughput

0.238

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024