Protein: RIR4
Ribonucleoside-diphosphate reductase small chain 2 (EC 1.17.4.1) (Ribonucleotide reductase R2 subunit 2) (Ribonucleotide reductase small subunit 2)

Gene: RIR4, RNR4
Organism: Saccharomyces cerevisiae S288C
Interactions: 95
UniProt ID: P49723

Gene Ontology (top 5):
GO:0004748 - ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005971 - ribonucleoside-diphosphate reductase complex
GO:0009263 - deoxyribonucleotide biosynthetic process

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

456711

RIR2
Ribonucleoside-diphosphate reductase small chain 1

13

15

Small-scale

0.984

High

832192

RIR4
Ribonucleoside-diphosphate reductase small chain 2

3

15

Small-scale

0.834

High

599188

RIR1
Ribonucleoside-diphosphate reductase large chain 1

2

13

Small-scale

0.777

High

832215

WTM1
Transcriptional modulator WTM1

5

3

Small-scale

0.721

High

832213

WTM2
Transcriptional modulator WTM2

5

3

Small-scale

0.707

High

491790

HSP71
Heat shock protein SSA1

5

6

Small-scale

0.697

High

366575

HSP82
ATP-dependent molecular chaperone HSP82

4

5

High-throughput

0.676

High

494409

HSP72
Heat shock protein SSA2

3

6

Small-scale

0.629

High

599978

RIR3
Ribonucleoside-diphosphate reductase large chain 2

1

13

High-throughput

0.618

High

689910

ASF1
Histone chaperone ASF1

2

1

High-throughput

0.601

High

832217

HUG1
MEC1-mediated checkpoint protein HUG1

2

1

Small-scale

0.595

High

628255

SIS1
Protein SIS1

2

3

High-throughput

0.588

High

680854

HS104
Heat shock protein 104

2

3

High-throughput

0.584

High

797474

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

1

High-throughput

0.584

High

633378

MAS5
Mitochondrial protein import protein MAS5

2

2

Small-scale

0.571

High

511951

SSB1
Ribosome-associated molecular chaperone SSB1

2

6

High-throughput

0.552

High

141902

DIF1
Damage-regulated import facilitator 1

1

1

Small-scale

0.501

High

565691

PHO85
Cyclin-dependent protein kinase PHO85

1

1

High-throughput

0.501

High

703241

PRP40
Pre-mRNA-processing protein PRP40

1

2

High-throughput

0.501

High

752158

KSP1
Serine/threonine-protein kinase KSP1

1

1

High-throughput

0.501

High

832193

FMP48
Probable serine/threonine-protein kinase FMP48

1

1

High-throughput

0.501

High

832206

ESA1
Histone acetyltransferase ESA1

1

1

Small-scale

0.501

High

597861

PWP1
Periodic tryptophan protein 1

1

4

High-throughput

0.500

High

690845

HIR1
Protein HIR1

1

2

High-throughput

0.500

High

832199

CAC2
Chromatin assembly factor 1 subunit p60

1

2

High-throughput

0.500

High

410230

UBC2
Ubiquitin-conjugating enzyme E2 2

1

0

High-throughput

0.493

High

832197

IMA1
Importin subunit alpha

1

0

High-throughput

0.493

High

832201

IMB1
Importin subunit beta-1

1

0

High-throughput

0.493

High

832207

YP191
Ubiquitin carboxyl-terminal hydrolase MIY1

1

0

High-throughput

0.493

High

815316

CTH1
mRNA decay factor CTH1

1

3

Small-scale

0.481

High

815323

CTH2
mRNA decay factor CTH2

1

3

Small-scale

0.481

High

832216

CMR1
DNA damage-binding protein CMR1

1

1

High-throughput

0.481

High

539386

KSS1
Mitogen-activated protein kinase KSS1

1

0

High-throughput

0.480

High

611005

ESS1
Peptidyl-prolyl cis-trans isomerase ESS1

1

0

High-throughput

0.480

High

648209

KCC1
Calcium/calmodulin-dependent protein kinase I

1

0

High-throughput

0.480

High

730522

KKQ8
Probable serine/threonine-protein kinase KKQ8

1

0

High-throughput

0.480

High

797294

WWM1
WW domain-containing protein WWM1

1

0

High-throughput

0.480

High

809739

CTK2
CTD kinase subunit beta

1

0

High-throughput

0.480

High

810338

SET2
Histone-lysine N-methyltransferase, H3 lysine-36 specific

1

0

High-throughput

0.480

High

810816

IKS1
Probable serine/threonine-protein kinase IKS1

1

0

High-throughput

0.480

High

832200

ISR1
Serine/threonine-protein kinase ISR1

1

0

High-throughput

0.480

High

832204

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.480

High

832205

PSK2
Serine/threonine-protein kinase PSK2

1

0

High-throughput

0.480

High

778507

PAC11
WD repeat-containing protein PAC11

1

0

High-throughput

0.479

High

544066

HSC82
ATP-dependent molecular chaperone HSC82

1

5

High-throughput

0.479

High

558145

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

1

High-throughput

0.479

High

662735

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.479

High

732202

SRX1
Sulfiredoxin

1

1

High-throughput

0.479

High

753879

RPN1
26S proteasome regulatory subunit RPN1

1

1

High-throughput

0.479

High

756980

RPN10
26S proteasome regulatory subunit RPN10

1

1

High-throughput

0.479

High

764999

IF4F1
Eukaryotic initiation factor 4F subunit p150

1

1

High-throughput

0.479

High

832194

PIL1
Sphingolipid long chain base-responsive protein PIL1

1

1

High-throughput

0.479

High

832195

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

1

High-throughput

0.479

High

832202

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

832203

TFC6
Transcription factor tau 91 kDa subunit

1

1

High-throughput

0.479

High

832209

YO283
Broad-specificity phosphatase YOR283W

1

1

High-throughput

0.479

High

832210

YL11B
Transposon Ty1-LR1 Gag-Pol polyprotein

1

1

High-throughput

0.479

High

343409

TPIS
Triosephosphate isomerase

1

0

High-throughput

0.458

High

389306

HXKA
Hexokinase-1

1

0

High-throughput

0.458

High

411043

PDC1
Pyruvate decarboxylase isozyme 1

1

0

High-throughput

0.458

High

421778

KAD2
Adenylate kinase

1

0

High-throughput

0.458

High

606700

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

0

High-throughput

0.458

High

716287

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

716465

SPT21
Protein SPT21

1

0

High-throughput

0.458

High

768313

YEY6
MYG1 protein YER156C

1

0

Small-scale

0.458

High

774044

PANC
Pantoate--beta-alanine ligase

1

0

High-throughput

0.458

High

812041

MOG1
Nuclear import protein MOG1

1

0

High-throughput

0.458

High

832211

RRP6
Exosome complex exonuclease RRP6

1

0

High-throughput

0.458

High

832212

SCC1
Sister chromatid cohesion protein 1

1

0

High-throughput

0.458

High

784622

BNI1
Protein BNI1

1

1

High-throughput

0.457

High

450107

HSP73
Heat shock protein SSA3

1

6

High-throughput

0.445

High

695067

HSP7F
Heat shock protein homolog SSE1

1

9

High-throughput

0.445

High

705408

HSP78
Heat shock protein 78, mitochondrial

1

3

High-throughput

0.445

High

761386

XDJ1
DnaJ protein homolog XDJ1

1

2

High-throughput

0.445

High

762147

YM11
Uncharacterized protein YMR124W

1

1

High-throughput

0.445

High

768895

SSB2
Ribosome-associated molecular chaperone SSB2

1

6

High-throughput

0.445

High

733871

RPF2
Ribosome biogenesis protein RPF2

1

1

High-throughput

0.437

High

832196

MLP1
Protein MLP1

1

2

High-throughput

0.437

High

832208

AP3D
AP-3 complex subunit delta

1

1

High-throughput

0.437

High

675757

RENT1
ATP-dependent helicase NAM7

1

0

High-throughput

0.426

High

734140

PXL1
Paxillin-like protein 1

1

0

High-throughput

0.426

High

792383

TCPH
T-complex protein 1 subunit eta

1

0

High-throughput

0.426

High

832214

HSP42
Heat shock protein 42

1

0

High-throughput

0.426

High

817278

HLJ1
Protein HLJ1

1

2

High-throughput

0.407

High

474266

NFT1
ABC transporter NFT1

1

0

High-throughput

0.282

High

832198

PKH3
Serine/threonine-protein kinase PKH3

1

0

High-throughput

0.261

Low

701227

SUI1
Eukaryotic translation initiation factor eIF-1

1

0

High-throughput

0.261

Low

772649

UTP18
U3 small nucleolar RNA-associated protein 18

1

0

High-throughput

0.261

Low

474288

YK104
Putative uncharacterized protein YKR104W

1

0

High-throughput

0.251

Low

521010

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.249

Low

745761

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

747398

PHO88
SRP-independent targeting protein 3

1

0

High-throughput

0.249

Low

750962

YGP1
Protein YGP1

1

0

High-throughput

0.249

Low

832218

ENV10
SRP-independent targeting protein 2

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024