Protein: CHK1
Serine/threonine-protein kinase chk1 (EC 2.7.11.1) (Checkpoint kinase 1)

Gene: CHK1
Organism: Schizosaccharomyces pombe 972h-
Interactions: 20
UniProt ID: P34208

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0004674 - protein serine/threonine kinase activity
GO:0005524 - ATP binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

444666

MPIP
M-phase inducer phosphatase

5

3

Small-scale

0.915

High

410438

CDK1
Cyclin-dependent kinase 1

2

2

Small-scale

0.789

High

757681

RAD24
Checkpoint signal transducer rad24

6

9

Small-scale

0.730

High

757684

RAD3
Protein kinase rad3

4

6

Small-scale

0.694

High

757683

RHP9
DNA repair protein crb2

5

0

Small-scale

0.689

High

376445

CDC10
Start control protein cdc10

1

0

Small-scale

0.687

High

757680

CEK1
Serine/threonine-protein kinase cek1

1

15

Small-scale

0.656

High

458203

WEE1
Mitosis inhibitor protein kinase wee1

1

10

Small-scale

0.647

High

757679

CHK1
Serine/threonine-protein kinase chk1

1

17

Small-scale

0.647

High

149407

DED1
ATP-dependent RNA helicase ded1

2

3

Small-scale

0.627

High

237837

HIM1
Hsk1-interacting molecule 1

1

0

Small-scale

0.586

High

735875

RAD4
S-M checkpoint control protein rad4

2

1

Small-scale

0.584

High

757682

RAD25
Checkpoint signal transducer rad25

1

9

Small-scale

0.552

High

151754

RFP1
E3 ubiquitin-protein ligase complex slx8-rfp subunit rfp1

1

0

Small-scale

0.549

High

151767

DCP2
mRNA decapping complex subunit 2

1

0

Small-scale

0.486

High

757685

PCNA
Proliferating cell nuclear antigen

1

3

Small-scale

0.481

High

757686

IPI3
Pre-rRNA-processing protein crb3/ipi3

1

2

Small-scale

0.481

High

154064

CBH1
CENP-B homolog protein 1

1

0

High-throughput

0.460

High

268460

YCS3
Uncharacterized calcium-binding protein C613.03

1

0

Small-scale

0.265

Low


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Last updated: 11Aug2025