Protein: HES4
Transcription factor HES-4 (hHES4) (Class B basic helix-loop-helix protein 42) (bHLHb42) (Hairy and enhancer of split 4) (bHLH factor Hes4)

Gene: HES4
Organism: Homo sapiens
Interactions: 34
UniProt ID: Q9HCC6

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0005634 - nucleus
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1327949

PHS2
Pterin-4-alpha-carbinolamine dehydratase 2

1

1

High-throughput

0.541

High

834926

RGS3
Regulator of G-protein signaling 3

1

0

High-throughput

0.537

High

668039

SPB3
Serpin B3

1

4

High-throughput

0.536

High

980651

TLE1
Transducin-like enhancer protein 1

1

20

High-throughput

0.536

High

791999

HD
Huntingtin

1

2

High-throughput

0.515

High

966203

NC2B
Protein Dr1

1

1

High-throughput

0.515

High

1025970

TADBP
TAR DNA-binding protein 43

1

1

High-throughput

0.515

High

1335940

PUS1
Pseudouridylate synthase 1 homolog

1

0

High-throughput

0.513

High

900076

PHS
Pterin-4-alpha-carbinolamine dehydratase

1

1

High-throughput

0.494

High

742544

SYUA
Alpha-synuclein

1

0

High-throughput

0.493

High

959975

TF2B
Transcription initiation factor IIB

1

0

High-throughput

0.493

High

245842

CATL2
Cathepsin L2

1

1

High-throughput

0.489

High

259887

LX12B
Arachidonate 12-lipoxygenase, 12R-type

1

1

High-throughput

0.489

High

453987

CATH
Pro-cathepsin H [Cleaved into: Cathepsin H mini chain; Cathepsin H

1

1

High-throughput

0.489

High

839507

SPB8
Serpin B8

1

4

High-throughput

0.489

High

1218301

SPA12
Serpin A12

1

4

High-throughput

0.489

High

438543

HS90B
Heat shock protein HSP 90-beta

1

3

High-throughput

0.479

High

1132740

ZC3HD
Zinc finger CCCH domain-containing protein 13

1

2

High-throughput

0.479

High

1309131

CMS1
Protein CMSS1

1

0

High-throughput

0.458

High

149312

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.437

High

296982

LTN1
E3 ubiquitin-protein ligase listerin

1

0

High-throughput

0.292

High

1335938

COPG2
Coatomer subunit gamma-2

1

0

High-throughput

0.292

High

611340

TGM1
Protein-glutamine gamma-glutamyltransferase K

1

0

High-throughput

0.279

Low

787785

HUTH
Histidine ammonia-lyase

1

0

High-throughput

0.279

Low

879435

FCGRN
IgG receptor FcRn large subunit p51

1

0

High-throughput

0.279

Low

1134427

KPRP
Keratinocyte proline-rich protein

1

0

High-throughput

0.279

Low

1243650

DR9C7
Short-chain dehydrogenase/reductase family 9C member 7

1

0

High-throughput

0.279

Low

1300234

GSDMA
Gasdermin-A

1

0

High-throughput

0.279

Low

1304055

PAFA2
Platelet-activating factor acetylhydrolase 2, cytoplasmic

1

0

High-throughput

0.279

Low

1335939

TF3C3
General transcription factor 3C polypeptide 3

1

0

High-throughput

0.268

Low

229888

KIF5C
Kinesin heavy chain isoform 5C

1

0

High-throughput

0.249

Low

623175

EF1B
Elongation factor 1-beta

1

0

High-throughput

0.249

Low

1119119

AT134
Probable cation-transporting ATPase 13A4

1

0

High-throughput

0.249

Low

1295423

LRIQ1
Leucine-rich repeat and IQ domain-containing protein 1

1

0

High-throughput

0.249

Low


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Last updated: 15 Jul 2024