Interactor 1: TNF14 (O43557)
Tumor necrosis factor ligand superfamily member 14 (Herpes virus entry mediator ligand) (HVEM-L) (Herpesvirus entry mediator ligand) (CD antigen CD258) [Cleaved into: Tumor necrosis factor ligand superfamily member 14, membrane form; Tumor necrosis factor ligand superfamily member 14, soluble form]
Gene: TNFSF14

Interactor 2: TNF6B (O95407)
Tumor necrosis factor receptor superfamily member 6B (Decoy receptor 3) (DcR3) (Decoy receptor for Fas ligand) (M68)
Gene: TNFRSF6B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.930

The method score is based on:

Property Details
Experiments 11390428, 10318773, 11994433, 21300286, 25087510
Identification Methods pull down, affinity chromatography technology, surface plasmon resonance, molecular sieving, x-ray crystallography, static light scattering, anti tag coimmunoprecipitation, fluorescence-activated cell sorting
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains TNF~TNFR_c6
Common GO terms GO:0005615 - extracellular space
GO:0006915 - apoptotic process
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 240
Hs

1 300
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024