Protein: BHE41
Class E basic helix-loop-helix protein 41 (bHLHe41) (Class B basic helix-loop-helix protein 3) (bHLHb3) (Differentially expressed in chondrocytes protein 2) (hDEC2) (Enhancer-of-split and hairy-related protein 1) (SHARP-1)

Gene: BHE41, BHLHE41
Organism: Homo sapiens
Interactions: 38
UniProt ID: Q9C0J9

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 - DNA-binding transcription repressor activity, RNA polymerase II-specific

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1319427

BHE41
Class E basic helix-loop-helix protein 41

3

17

Small-scale

0.835

High

1085667

HIF1A
Hypoxia-inducible factor 1-alpha

1

19

Small-scale

0.715

High

546043

MYOD1
Myoblast determination protein 1

1

13

Small-scale

0.647

High

181561

CLOCK
Circadian locomoter output cycles protein kaput

1

19

High-throughput

0.621

High

146542

BHE40
Class E basic helix-loop-helix protein 40

1

19

Small-scale

0.618

High

1038691

HDAC1
Histone deacetylase 1

2

6

Small-scale

0.595

High

1031606

ATM
Serine-protein kinase ATM

1

1

High-throughput

0.536

High

1291113

CDCA5
Sororin

1

0

High-throughput

0.513

High

1319428

MKNK2
MAP kinase-interacting serine/threonine-protein kinase 2

1

0

High-throughput

0.513

High

1319430

POLK
DNA polymerase kappa

1

0

High-throughput

0.513

High

1289420

SIR1
NAD-dependent protein deacetylase sirtuin-1

1

7

Small-scale

0.501

High

1158577

L2GL2
LLGL scribble cell polarity complex component 2

1

2

High-throughput

0.489

High

166010

PER2
Period circadian protein homolog 2

1

19

High-throughput

0.481

High

586966

CSK22
Casein kinase II subunit alpha'

1

12

High-throughput

0.481

High

672471

2AAB
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

1

2

High-throughput

0.481

High

723195

RORA
Nuclear receptor ROR-alpha

1

14

High-throughput

0.481

High

830471

KC1E
Casein kinase I isoform epsilon

1

5

High-throughput

0.481

High

835982

GSK3B
Glycogen synthase kinase-3 beta

1

5

High-throughput

0.481

High

846426

RORG
Nuclear receptor ROR-gamma

1

20

High-throughput

0.481

High

903499

WDR5
WD repeat-containing protein 5

1

3

High-throughput

0.481

High

915276

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

6

High-throughput

0.481

High

931850

CSK2B
Casein kinase II subunit beta

1

6

High-throughput

0.481

High

934457

CSK21
Casein kinase II subunit alpha

1

15

High-throughput

0.481

High

1069786

NONO
Non-POU domain-containing octamer-binding protein

1

2

High-throughput

0.481

High

1082153

CRY1
Cryptochrome-1

1

10

High-throughput

0.481

High

1082537

2A5E
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit epsilon isoform

1

3

High-throughput

0.481

High

1115754

CRY2
Cryptochrome-2

1

10

High-throughput

0.481

High

1319431

FBW1B
F-box/WD repeat-containing protein 11

1

9

High-throughput

0.481

High

1319433

RASD1
Dexamethasone-induced Ras-related protein 1

1

2

High-throughput

0.481

High

570046

CEBPB
CCAAT/enhancer-binding protein beta

1

6

Small-scale

0.479

High

587197

RXRA
Retinoic acid receptor RXR-alpha

1

8

Small-scale

0.479

High

638190

PSA4
Proteasome subunit alpha type-4

1

2

Small-scale

0.479

High

1300930

CIC
Protein capicua homolog

1

3

High-throughput

0.479

High

1319429

DEC1
Deleted in esophageal cancer 1

1

1

High-throughput

0.439

High

264742

VP26A
Vacuolar protein sorting-associated protein 26A

1

0

High-throughput

0.279

Low

1160002

KLC3
Kinesin light chain 3

1

0

High-throughput

0.279

Low

1319432

MYH13
Myosin-13

1

0

High-throughput

0.279

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024