Protein: CO5
Complement C5 (C3 and PZP-like alpha-2-macroglobulin domain-containing protein 4) [Cleaved into: Complement C5 beta chain; Complement C5 alpha chain; C5a anaphylatoxin; Complement C5 alpha' chain]

Gene: CO5, C5
Organism: Homo sapiens
Interactions: 33
UniProt ID: P01031

Gene Ontology (top 5):
GO:0004866 - endopeptidase inhibitor activity
GO:0005102 - signaling receptor binding
GO:0005576 - extracellular region
GO:0005579 - membrane attack complex
GO:0005615 - extracellular space

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

344753

CO6
Complement component C6

2

10

Small-scale

0.778

High

198332

KLK10
Kallikrein-10

1

8

High-throughput

0.691

High

344608

CO3
Complement C3

1

3

Small-scale

0.647

High

344750

CO8B
Complement component C8 beta chain

1

5

Small-scale

0.647

High

344752

CO7
Complement component C7

1

13

Small-scale

0.647

High

170762

PGRC2
Membrane-associated progesterone receptor component 2

2

0

High-throughput

0.580

High

344763

ANKS6
Ankyrin repeat and SAM domain-containing protein 6

2

1

High-throughput

0.553

High

344766

EMC5
ER membrane protein complex subunit 5

2

1

High-throughput

0.553

High

344767

KI3L3
Killer cell immunoglobulin-like receptor 3DL3

2

2

High-throughput

0.553

High

344757

CCR1
C-C chemokine receptor type 1

1

5

High-throughput

0.536

High

344755

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

8

Small-scale

0.501

High

344770

CBPB2
Carboxypeptidase B2

1

2

Small-scale

0.501

High

344762

UBE2U
Ubiquitin-conjugating enzyme E2 U

1

3

High-throughput

0.489

High

344765

RYBP
RING1 and YY1-binding protein

1

5

High-throughput

0.489

High

344771

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

5

High-throughput

0.489

High

344773

PHF11
PHD finger protein 11

1

5

High-throughput

0.489

High

344751

CATB
Cathepsin B

1

1

Small-scale

0.479

High

344754

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.458

High

344774

ITM2B
Integral membrane protein 2B

1

5

High-throughput

0.445

High

260427

PITX3
Pituitary homeobox 3

1

3

Small-scale

0.437

High

344748

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

3

High-throughput

0.437

High

344749

GCR
Glucocorticoid receptor

1

5

High-throughput

0.437

High

344758

SOX2
Transcription factor SOX-2

1

4

High-throughput

0.437

High

147045

NEMP1
Nuclear envelope integral membrane protein 1

2

0

High-throughput

0.316

High

344756

KELL
Kell blood group glycoprotein

2

0

High-throughput

0.316

High

344759

PO6F2
POU domain, class 6, transcription factor 2

2

0

High-throughput

0.316

High

344760

AQP6
Aquaporin-6

2

0

High-throughput

0.316

High

344761

EBP
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase

2

0

High-throughput

0.316

High

344764

CPLX4
Complexin-4

2

0

High-throughput

0.316

High

344768

SSMM1
Serine-rich single-pass membrane protein 1

2

0

High-throughput

0.316

High

344769

CR3L1
Cyclic AMP-responsive element-binding protein 3-like protein 1

1

0

High-throughput

0.299

High

344747

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

0

High-throughput

0.251

Low

344772

VEZA
Vezatin

1

0

High-throughput

0.251

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024